Bladder hyperactivity and increased excitability of bladder afferent neurons associated with reduced expression of Kv1.4 α-subunit in rats with cystitis

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 296, Issue 5, 2009, Pages

  Hayashi, Yukio ^a   Takimoto, Koichi ^b   Chancellor, Michael B ^a   Erickson, Kristin A ^a   Erickson, Vickie L ^a   Kirimoto, Tsukasa ^c   Nakano, Koushi ^c   De Groat, William C ^a   Yoshimura, Naoki ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PITTSBURGH GRADUATE SCHOOL OF PUBLIC HEALTH   (United States)

^c TAIHO PHARMACEUTICAL CO LTD   (Japan)

Author keywords

C fiber afferent; Hyperalgesia; Inflammation; Potassium channel; Urinary bladder

Indexed keywords

CAPSAICIN; FAST BLUE; HYDROCHLORIC ACID; POTASSIUM CHANNEL KV1.4;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLADDER FUNCTION; CONTROLLED STUDY; CYSTALGIA; CYSTOMETRY; ELECTRODIAGNOSIS; ELECTROPHYSIOLOGY; FEMALE; HYPERALGESIA; IMMUNOHISTOCHEMISTRY; INTERSTITIAL CYSTITIS; NERVE EXCITABILITY; NONHUMAN; OVERACTIVE BLADDER; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SENSORY NERVE; SPIKE WAVE;

ANIMALS; CAPSAICIN; CYSTITIS; DISEASE MODELS, ANIMAL; FEMALE; HYDROCHLORIC ACID; KV1.4 POTASSIUM CHANNEL; NERVE FIBERS, UNMYELINATED; NEURONS, AFFERENT; PATCH-CLAMP TECHNIQUES; PROTEIN SUBUNITS; RATS; RATS, SPRAGUE-DAWLEY; SENSORY SYSTEM AGENTS; URINARY BLADDER; URINARY BLADDER, OVERACTIVE;

EID: 66149098481     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.91054.2008     Document Type: Article

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