Sc(OTf)3-catalyzed conjugate allylation of alkylidene meldrum's acids

Organic Letters

Volumn 11, Issue 9, 2009, Pages 1919-1922

  Dumas, Aaron M ^a   Fillion, Eric ^a  

^a UNIVERSITY OF WATERLOO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 66149097468     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol9003959     Document Type: Article

References (52)

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41. The initial product formed by allylation is a triphenyltin enolate of Meldrum's acid that is protonated by acidic workup. See Supporting Information.
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48. Relative stereochemistry was determined by analysis of coupling constants and proceeds with the same facial selectivity as the addition of indole (ref 22).
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51. Similar products have been obtained by the reaction of alkylidene Meldrum's acids with butadiene sulfone: Fillion, E.; Dumas, A. M.; Hogg, S. A. J. Org. Chem. 2006, 71, 9899-9902.
52. See Supporting Information for details.