Activation of NF-κB is a critical element in the antiapoptotic effect of anesthetic preconditioning

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 296, Issue 5, 2009, Pages

  Lu, Xiyuan ^a   Liu, Hong ^b   Wang, Lianguo ^d   Schaefer, Saul ^a,b,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c Northern California Health Care System   (United States)

^d UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Nuclear factor B; Reactive oxygen species

Indexed keywords

CASPASE 3; CYTOCHROME C; I KAPPA B KINASE; I KAPPA B KINASE ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; SEVOFLURANE; CASP3 PROTEIN, RAT; ETHER DERIVATIVE; I KAPPA B; INHALATION ANESTHETIC AGENT; NF KAPPAB INHIBITOR ALPHA; NF-KAPPAB INHIBITOR ALPHA; PROTEIN KINASE INHIBITOR; SC 514; THIOPHENE DERIVATIVE;

ANESTHESIA; ANESTHESIA INDUCTION; ANESTHETIC PRECONDITIONING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; CONVALESCENCE; ENZYME DEGRADATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; ENZYME RELEASE; HEART INJURY; HEART LEFT VENTRICLE FUNCTION; HEART MUSCLE ISCHEMIA; HEART VENTRICLE ENDDIASTOLIC PRESSURE; ISOLATED HEART; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SECRETION; RAT; REPERFUSION INJURY; ANIMAL; DRUG ANTAGONISM; DRUG EFFECT; HEART MUSCLE; HEART VENTRICLE PRESSURE; IN VITRO STUDY; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; PERFUSION; PHOSPHORYLATION; SPRAGUE DAWLEY RAT;

ANESTHETICS, INHALATION; ANIMALS; APOPTOSIS; CASPASE 3; CYTOCHROMES C; I-KAPPA B KINASE; I-KAPPA B PROTEINS; MALE; METHYL ETHERS; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; NF-KAPPA B; PERFUSION; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; RECOVERY OF FUNCTION; THIOPHENES; VENTRICULAR FUNCTION, LEFT; VENTRICULAR PRESSURE;

EID: 66149094966     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.01282.2008     Document Type: Article

References (54)

1. 2+ responses in intact hearts. Am J Physiol Heart Circ Physiol 281: H1508-H1523, 2001.
2. Bouwman RA, Musters RJ, van Beek-Harmsen BJ, de Lange JJ, Boer C. Reactive oxygen species precede protein kinase C-delta activation independent of adenosine triphosphate-sensitive mitochondrial channel opening in sevoflurane-induced cardioprotection. Anesthesiology 100: 506-514, 2004. (Pubitemid 38268866)
3. Bouwman RA, Musters RJ, van Beek-Harmsen BJ, de Lange JJ, Lamberts RR, Loer SA, Boer C. Sevoflurane-induced cardioprotection depends on PKC-alpha activation via production of reactive oxygen species. Br J Anaesth 99: 639-645, 2007.
4. Bowie A, O'Neill LA. Oxidative stress and nuclear factor-kappaB activation: a reassessment of the evidence in the light of recent discoveries. Biochem Pharmacol 59: 13-23, 2000.
5. ATP channels. Anesthesiology 97: 912-920, 2002.
6. Choi H, Kim SH, Chun YS, Cho YS, Park JW, Kim MS. In vivo hyperoxic preconditioning prevents myocardial infarction by expressing bcl-2. Exp Biol Med (Maywood) 231: 463-472, 2006.
7. Christman JW, Lancaster LH, Blackwell TS. Nuclear factor kappa B: a pivotal role in the systemic inflammatory response syndrome and new target for therapy. Intensive Care Med 24: 1131-1138, 1998.
8. De Hert SG, Turani F, Mathur S, Stowe DF. Cardioprotection with volatile anesthetics: mechanisms and clinical implications. Anesth Analg 100: 1584-1593, 2005. (Pubitemid 40712704)
9. 2+ overload during ischemia/reperfusion: role of reactive oxygen species. Exp Clin Cardiol 10: 96-103, 2005.
10. Efstathiou A, Seraskeris S, Papakonstantinou C, Aidonopoulos A, Lazou A. Differential effect of preconditioning on post-ischaemic myocardial performance in the absence of substantial infarction and in extensively infarcted rat hearts. Eur J Cardiothorac Surg 19: 493-499, 2001. (Pubitemid 32303152)
11. Eisner V, Criollo A, Quiroga C, Olea-Azar C, Santibanez JF, Troncoso R, Chiong M, Diaz-Araya G, Foncea R, Lavandero S. Hyperosmotic stress-dependent NFkappaB activation is regulated by reactive oxygen species and IGF-1 in cultured cardiomyocytes. FEBS Lett 580: 4495-4500, 2006. (Pubitemid 44118276)
12. El Eter E, Hagar HH, Al-Tuwaijiri A, Arafa M. Nuclear factor-kappaB inhibition by pyrrolidinedithiocarbamate attenuates gastric ischemia-reperfusion injury in rats. Can J Physiol Pharmacol 83: 483-492, 2005. (Pubitemid 41176366)
13. Frassdorf J, Weber NC, Obal D, Toma O, Mullenheim J, Kojda G, Preckel B, Schlack W. Morphine induces late cardioprotection in rat hearts in vivo: the involvement of opioid receptors and nuclear transcription factor kappaB. Anesth Analg 101: 934-941, 2005. (Pubitemid 41383050)
14. Hanouz JL, Zhu L, Lemoine S, Durand C, Lepage O, Massetti M, Khayat A, Plaud B, Gerard JL. Reactive oxygen species mediate sevoflurane- and desflurane-induced preconditioning in isolated human right atria in vitro. Anesth Analg 105: 1534-1539, 2007. (Pubitemid 350190540)
15. Julier K, da Silva R, Garcia C, Bestmann L, Frascarolo P, Zollinger A, Chassot PG, Schmid ER, Turina MI, von Segesser LK, Pasch T, Spahn DR, Zaugg M. Preconditioning by sevoflurane decreases biochemical markers for myocardial and renal dysfunction in coronary artery bypass graft surgery: a double-blinded, placebo-controlled, multicenter study. Anesthesiology 98: 1315-1327, 2003.
16. Kajstura J, Cheng W, Reiss K, Clark WA, Sonnenblick EH, Krajewski S, Reed JC, Olivetti G, Anversa P. Apoptotic and necrotic myocyte cell deaths are independent contributing variables of infarct size in rats. Lab Invest 74: 86-107, 1996. (Pubitemid 26041012)
17. Kaneda K, Miyamae M, Sugioka S, Okusa C, Inamura Y, Domae N, Kotani J, Figueredo VM. Sevoflurane enhances ethanol-induced cardiac preconditioning through modulation of protein kinase C, mitochondrial KATP channels, and nitric oxide synthase, in guinea pig hearts. Anesth Analg 106: 9-16, 2008.
18. Kersten JR, Schmeling TJ, Pagel PS, Gross GJ, Warltier DC. Isoflurane mimics ischemic preconditioning via activation of KATP channels: reduction of myocardial infarct size with an acute memory phase. Anesthesiology 87: 361-370, 1997.
19. Kevin LG, Novalija E, Riess ML, Camara AK, Rhodes SS, Stowe DF. Sevoflurane exposure generates superoxide but leads to decreased superoxide during ischemia and reperfusion in isolated hearts. Anesth Analg 96: 949-955, 2003. (Pubitemid 36359021)
20. Kevin LG, Novalija E, Stowe DF. Reactive oxygen species as mediators of cardiac injury and protection: the relevance to anesthesia practice. Anesth Analg 101: 1275-1287, 2005. (Pubitemid 41531857)
21. Kishore N, Sommers C, Mathialagan S, Guzova J, Yao M, Hauser S, Huynh K, Bonar S, Mielke C, Albee L, Weier R, Graneto M, Hanau C, Perry T, Tripp CS. A selective IKK-2 inhibitor blocks NF-kappa B-dependent gene expression in interleukin-1 beta-stimulated synovial fibroblasts. J Biol Chem 278: 32861-32871, 2003. (Pubitemid 37055728)
22. Knebel F, Schimke I, Pliet K, Schattke S, Martin S, Borges AC, Baumann G. NT-ProBNP in acute heart failure: correlation with invasively measured hemodynamic parameters during recompensation. J Card Fail 11: S38-S41, 2005.
23. Landoni G, Biondi-Zoccai GG, Zangrillo A, Bignami E, D'Avolio S, Marchetti C, Calabro MG, Fochi O, Guarracino F, Tritapepe L, De Hert S, Torri G. Desflurane and sevoflurane in cardiac surgery: a meta-analysis of randomized clinical trials. J Cardiothorac Vasc Anesth 21: 502-511, 2007. (Pubitemid 47135634)
24. Lee MC, Chen CH, Kuo MC, Kang PL, Lo A, Liu K. Isoflurane preconditioning-induced cardio-protection in patients undergoing coronary artery bypass grafting. Eur J Anaesthesiol 23: 841-847, 2006. (Pubitemid 44464934)
25. Li C, Browder W, Kao RL. Early activation of transcription factor NF-κB during ischemia in perfused rat heart. Am J Physiol Heart Circ Physiol 276: H543-H552, 1999. (Pubitemid 29100623)
26. Li C, Kao RL, Ha T, Kelley J, Browder IW, Williams DL. Early activation of IKK-β during in vivo myocardial ischemia. Am J Physiol Heart Circ Physiol 280: H1264-H1271, 2001. (Pubitemid 32537890)
27. 2+ in ischemic newborn myocardium. Anesth Analg 101: 349-355, 2005.
28. Liu X, Shen J, Jin Y, Duan M, Xu J. Recombinant human erythropoietin (rhEPO) preconditioning on nuclear factor-kappa B (NF-κB) activation and proinflammatory cytokines induced by myocardial ischaemia-reperfusion. Indian J Med Res 124: 343-354, 2006.
29. Lutz M, Liu H. Inhaled sevoflurane produces better delayed myocardial protection at 48 versus 24 hours after exposure. Anesth Analg 102: 984-990, 2006.
30. Maulik N, Goswami S, Galang N, Das DK. Differential regulation of Bcl-2, AP-1 and NF-kappaB on cardiomyocyte apoptosis during myocardial ischemic stress adaptation. FEBS Lett 443: 331-336, 1999. (Pubitemid 29080821)
31. Mullenheim J, Molojavyi A, Preckel B, Thamer V, Schlack W. Thiopentone does not block ischemic preconditioning in the isolated rat heart. Can J Anaesth 48: 784-789, 2001. (Pubitemid 33040236)
32. Nguyen LT, Rebecchi MJ, Moore LC, Glass PS, Brink PR, Liu L. Attenuation of isoflurane-induced preconditioning and reactive oxygen species production in the senescent rat heart. Anesth Analg 107: 776-782, 2008.
33. Novalija E, Kevin LG, Camara AK, Bosnjak ZJ, Kampine JP, Stowe DF. Reactive oxygen species precede the epsilon isoform of protein kinase C in the anesthetic preconditioning signaling cascade. Anesthesiology 99: 421-428, 2003. (Pubitemid 36909568)
34. Pagel PS. Induction of heat shock protein 70 and preconditioning by sevoflurane: a potent protective interaction against myocardial ischemia-reperfusion injury. Anesth Analg 107: 742-745, 2008.
35. Paparella D, Yau TM, Young E. Cardiopulmonary bypass induced inflammation: pathophysiology and treatment. An update. Eur J Cardiothorac Surg 21: 232-244, 2002. (Pubitemid 34135370)
36. Petersen CA, Krumholz KA, Carmen J, Sinai AP, Burleigh BA. Trypanosoma cruzi infection and nuclear factor kappa B activation prevent apoptosis in cardiac cells. Infect Immun 74: 1580-1587, 2006. (Pubitemid 43346791)
37. Qian LP, Zhu SS, Cao JL, Zeng YM. Isoflurane preconditioning protects against ischemia-reperfusion injury partly by attenuating cytochrome c release from subsarcolemmal mitochondria in isolated rat hearts. Acta Pharmacol Sin 26: 813-820, 2005.
38. Raphael J, Abedat S, Rivo J, Meir K, Beeri R, Pugatsch T, Zuo Z, Gozal Y. Volatile anesthetic preconditioning attenuates myocardial apoptosis in rabbits after regional ischemia and reperfusion via Akt signaling and modulation of Bcl-2 family proteins. J Pharmacol Exp Ther 318: 186-194, 2006. (Pubitemid 43920755)
39. Regula KM, Baetz D, Kirshenbaum LA. Nuclear factor-kappaB represses hypoxia-induced mitochondrial defects and cell death of ventricular myocytes. Circulation 110: 3795-3802, 2004. (Pubitemid 40023978)
40. Regula KM, Ens K, Kirshenbaum LA. IKK beta is required for Bcl-2-mediated NF-kappa B activation in ventricular myocytes. J Biol Chem 277: 38676-38682, 2002. (Pubitemid 35154728)
41. Renard P, Ernest I, Houbion A, Art M, Le Calvez H, Raes M, Remacle J. Development of a sensitive multi-well colorimetric assay for active NFkappaB. Nucleic Acids Res 29: E21, 2001.
42. 2+ overload during ischemia in Guinea pig intact hearts: reversal by 5-hydroxydecanoic acid. Anesth Analg 95: 1540-1546, 2002.
43. Riess ML, Kevin LG, McCormick J, Jiang MT, Rhodes SS, Stowe DF. Anesthetic preconditioning: the role of free radicals in sevoflurane-induced attenuation of mitochondrial electron transport in Guinea pig isolated hearts. Anesth Analg 100: 46-53, 2005. (Pubitemid 40013601)
44. Riou B. Halogenated anesthetics and human myocardium. Anesthesiology 92: 1-2, 2000. (Pubitemid 30027438)
45. Siracusano L, Girasole V, Alvaro S, Chiavarino ND. Myocardial preconditioning and cardioprotection by volatile anaesthetics. J Cardiovasc Med (Hagerstown) 7: 86-95, 2006. (Pubitemid 44152948)
46. Sniecinski R, Liu H. Reduced efficacy of volatile anesthetic preconditioning with advanced age in isolated rat myocardium. Anesthesiology 100: 589-597, 2004. (Pubitemid 38268877)
47. Tahepold P, Vaage J, Starkopf J, Valen G. Hyperoxia elicits myocardial protection through a nuclear factor kappaB-dependent mechanism in the rat heart. J Thorac Cardiovasc Surg 125: 650-660, 2003. (Pubitemid 36373913)
48. Vatner SF, Baig H, Manders WT, Maroko PR. Effects of coronary artery reperfusion on myocardial infarct size calculated from creatine kinase. J Clin Invest 61: 1048-1056, 1978. (Pubitemid 8321082)
49. Wang S, Chen F, Zhang Z, Jiang BH, Jia L, Shi X. NF-kappaB prevents cells from undergoing Cr(VI)-induced apoptosis. Mol Cell Biochem 255: 129-137, 2004. (Pubitemid 38159773)
50. Wu D, Soong Y, Zhao GM, Szeto HH. A highly potent peptide analgesic that protects against ischemia-reperfusion-induced myocardial stunning. Am J Physiol Heart Circ Physiol 283: H783-H791, 2002.
51. Xia Z, Kuo KH, Godin DV, Walker MJ, Tao MC, Ansley DM. 15-F(2t)-isoprostane exacerbates myocardial ischemia-reperfusion injury of isolated rat hearts. Am J Physiol Heart Circ Physiol 289: H1366-H1372, 2005. (Pubitemid 41368976)
52. Yang H, Liang G, Hawkins BJ, Madesh M, Pierwola A, Wei H. Inhalational anesthetics induce cell damage by disruption of intracellular calcium homeostasis with different potencies. Anesthesiology 109: 243-250, 2008.
53. ATP channel. J Mol Cell Cardiol 34: 263-277, 2002.
54. Zhong C, Zhou Y, Liu H. Nuclear factor kappaB and anesthetic preconditioning during myocardial ischemia-reperfusion. Anesthesiology 100: 540-546, 2004. (Pubitemid 38268870)