Quality of life in multiple sclerosis is associated with lesion burden and brain volume measures

Neurology

Volumn 72, Issue 20, 2009, Pages 1760-1765

  Mowry, E M ^a,b   Beheshtian, A ^a   Waubant, E ^a   Goodin, D S ^a   Cree, B A ^a   Qualley, P ^a   Lincoln, R ^a   George, M F ^a   Gomez, R ^a   Hauser, S L ^a   Okuda, D T ^a   Pelletier, D ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UCSF Multiple Sclerosis Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; BRAIN ATROPHY; BRAIN SIZE; COHORT ANALYSIS; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTIPLE SCLEROSIS; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; PROSPECTIVE STUDY; QUALITY OF LIFE; SCORING SYSTEM; WELLBEING; WHITE MATTER; ADOLESCENT; AGED; BRAIN; CROSS-SECTIONAL STUDY; DISEASE COURSE; HISTOLOGY; MIDDLE AGED; NEUROPSYCHOLOGICAL TEST; PATHOLOGY; PATHOPHYSIOLOGY;

ADOLESCENT; ADULT; AGED; BRAIN; CROSS-SECTIONAL STUDIES; DISEASE PROGRESSION; FEMALE; HUMANS; MALE; MIDDLE AGED; MULTIPLE SCLEROSIS; NEUROPSYCHOLOGICAL TESTS; QUALITY OF LIFE; YOUNG ADULT;

EID: 66149091139     PISSN: 00283878     EISSN: 1526632X     Source Type: Journal    
DOI: 10.1212/WNL.0b013e3181a609f8     Document Type: Article

References (40)

1. Norcvedt MW, Riise T, Myhr KM, Nyland HI. Quality of life in multiple sclerosis: measuring the disease effects more broadly. Neurology 1999;53:1098-1103.
2. Miller DM, Kinkel RP. Health-related quality of life assessment in multiple sclerosis. Rev Neurol Dis 2008;5:56-64.
3. Pascual AM, Martinez-Bisbal MC, Bosca I, et al. Axonal loss is progressive and partly dissociated from lesion load in early multiple sclerosis. Neurology 2007;69:63-67.
4. Henry RG, Shieh M, Okuda DT, Evangelista A, Gorno-Tempini ML, Pelletier D. Regional grey matter atrophy in clinically isolated syndromes at presentation. J Neurol Neurosurg Psychiatry 2008;79:1236-1244.
5. Chard DT, Griffin CM, Parker GJ, Kapoor R, Thompson AJ, Miller DH. Brain atrophy in clinically early relapsing remitting multiple sclerosis. Brain 2002; 125:327-337.
6. Simon JH, Jacobs LD, Campion MK, et al. A longitudinal study of brain atrophy in relapsing multiple sclerosis. The Multiple Sclerosis Collaborative Research Group. Neurology 1999;53:139-148.
7. Trapp BD, Peterson J, Ransohoff RM, Rudick R, Mork S, Bo L. Axonal transection in the lesions of multiple sclerosis. N Engl J Med 1998;338:278-285.
8. Janssens AC, van Doom PA, de Boer JB, van der Meche FG, Passchier J, Hintzen RQ. Impact of recently diagnosed multiple sclerosis on quality of life, anxiety, depression and distress of partners. Acta Neural Scand 2003;108: 389-395.
9. McDonald WI, Compston A, Edan G, et al. Recommended diagnostic criteria for multiple sclerosis: guidelines from the international panel on the diagnosis of multiple sclerosis. Ann Neurol 2001:50:121-127.
10. Polman CH, Reingold SC, Edan G, et al. Diagnostic criteria for multiple sclerosis: 2005 revisions to the "McDonald criteria." Ann Neurol 2005;58:840-846.
11. Kurtzke JF. Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS). Neurology 1983;33:1444-1452.
12. Fischer JS, Rudick RA, Cutter GR, Reingold SC. The multiple sclerosis functional composite measure (MSFC): an integrated approach to MS clinical outcome assessment. Mult Scler 1999;5:244-250.
13. Cella DF, Dineen K, Arnason B, et al. Validation of the functional assessment of multiple sclerosis quality of life instrument. Neurology 1996;47:129-139.
14. Blum D, Yonelinas AP, Luks T, et al. Dissociating perceptual and conceptual implicit memory in multiple sclerosis patients. Brain Cogn 2002;50:51-61.
15. Samsa G, Edelman D, Rothman ML, Williams GR, Lips-comb J, Matchar D. Determining clinically important differences in health status measures. Pharmacoeconomics 1999:15:141-155.
16. Arnoldus JH, Killestein J, Pfennings LE, Jelles B, Uitde-haag BM, Polman CH. Quality of life during the first 6 months of interferon-beta treatment in patients with MS. Mult Scler 2000:6:338-342.
17. Rice GP, Oger J, Duquette P, et al. Treatment with inter-feron beta-lb improves quality of life in multiple sclerosis. Can J Neurol Sci 1999;26:276-282.
18. Vittinghoff E, Glidden DV, Shiboski SC, McCullouch CE. Regression Methods in Biostatistics. New York: Springer Science & Business Media; 2005.
19. Dalton CM, Chard DT, Davies GR, et al. Early development of multiple sclerosis is associated with progressive grey matter atrophy in patients presenting with clinically isolated syndromes. Brain 2004;127:1101-1107.
20. Losseff NA, Wang L, Lai HM, et al. Progressive cerebral atrophy in multiple sclerosis: a serial MRI study. Brain 1996;119:2009-2019.
21. Fisher E, Lee JC, Nakamura K, Rudick RA. Gray matter atrophy in multiple sclerosis: a longitudinal study. Ann Neurol 2008;64:255-265.
22. Fisniku LK, Chard DT, Jackson JS, et al. Gray matter atrophy is related to long-term disability in multiple sclerosis. Ann Neurol 2008;64:247-254.
23. Fisher E, Rudick RA, Cutter G, et al. Relationship between brain atrophy and disability: an 8-year follow-up study of multiple sclerosis patients. Mult Scler 2000;6: 373-377.
24. van der Werf SP, Jongen PJ, Lycklama a Nijeholt GJ, et al. Fatigue in multiple sclerosis: interrelations between fatigue complaints, cerebral MRI abnormalities and neurological disability. J Neurol Sci 1998;160:164-170.
25. Mainero C, Faroni J, Gasperini C, et al. Fatigue and magnetic resonance imaging activity in multiple sclerosis. J Neurol 1999;246:454-458.
26. Bakshi R, Miletich RS, Henschel K, et al. Fatigue in multiple sclerosis: cross-sectional correlation with brain MRI findings in 71 patients. Neurology 1999;53:1151-1153.
27. Janardhan V, Bakshi R. Quality of life and its relationship to brain lesions and atrophy on magnetic resonance images in 60 patients with multiple sclerosis. Arch Neurol 2000; 57:1485-1491.
28. Codella M, Rocca MA, Colombo B, Martinelli-Boneschi F, Comi G, Filippi M. Cerebral grey matter pathology and fatigue in patients with multiple sclerosis: a preliminary study. J Neurol Sci 2002;194:71-74.
29. Codella M, Rocca MA, Colombo B, Rossi P, Comi G, Filippi M. A preliminary study of magnetization transfer and diffusion tensor MRI of multiple sclerosis patients with fatigue. J Neurol 2002;249:535-537.
30. Marrie RA, Fisher E, Miller DM, Lee JC, Rudick RA. Association of fatigue and brain atrophy in multiple sclerosis. J Neurol Sci 2005;228:161-166.
31. Filippi M, Rocca MA, Colombo B, et al. Functional magnetic resonance imaging correlates of fatigue in multiple sclerosis. Neuroimage 2002;15:559-567.
32. Cook DB, O'Connor PJ, Lange G, Steffener J. Functional neuroimaging correlates of mental fatigue induced by cognition among chronic fatigue syndrome patients and controls. Neuroimage 2007;36:108-122.
33. Rocca MA, Agosta F, Colombo B, et al. fMRI changes in relapsing-remitting multiple sclerosis patients complaining of fatigue after IFNβ-1A injection. Hum Brain Mapp 2007;28:373-382.
34. de Lange FP, Kalkman JS, Bleijenberg G, Hagoort P, van der Meer JW, Toni I. Gray matter volume reduction in the chronic fatigue syndrome. Neuroimage 2005;26:777-781.
35. Christodoulou C, Krupp LB, Liang Z, et al. Cognitive performance and MR markers of cerebral injury in cognitively impaired MS patients. Neurology 2003;60:1793-1798.
36. Rovaris M, Filippi M, Falautano M, et al. Relation between MR abnormalities and patterns of cognitive impairment in multiple sclerosis. Neurology 1998;50:1601-1608.
37. Benedict RH, Weinstock-Guttman B, Fishman I, Sharma J, Tjoa CW, Bakshi R. Prediction of neuropsychological impairment in multiple sclerosis: comparison of conventional magnetic resonance imaging measures of atrophy and lesion burden. Arch Neurol 2004;61:226-230.
38. Zivadinov R, Sepcic J, Nasuelli D, et al. A longitudinal study of brain atrophy and cognitive disturbances in the early phase of relapsing-remitting multiple sclerosis. J Neural Neurosurg Psychiatry 2001;70:773-780.
39. Visschedijk MA, Uitdehaag BM, Klein M, et al. Value of health-related quality of life to predict disability course in multiple sclerosis. Neurology 2004;63:2046-2050.
40. Nortvedt MW, Riise T, Myhr KM, Nyland HI. Quality of life as predictor for change in disability in MS. Neurology 2000;55:51-54.