-
1
-
-
0037902947
-
2-Methoxyestradiol alters cell motility, migration, and adhesion
-
DOI 10.1182/blood-2002-03-0729
-
Sattler M, Quinnan LR, Pride YB, Gramlich JL, Chu SC, Even GC, Kraeft SK, Chen LB, Salgia R: 2-Methoxyestradiol alters cell motility, migration, and adhesion. Blood 2003; 102: 289-296. (Pubitemid 36759667)
-
(2003)
Blood
, vol.102
, Issue.1
, pp. 289-296
-
-
Sattler, M.1
Quinnan, L.R.2
Pride, Y.B.3
Gramlich, J.L.4
Chu, S.C.5
Even, G.C.6
Kraeft, S.-K.7
Chen, L.B.8
Salgia, R.9
-
2
-
-
0037439693
-
2-Methoxyestradiol up-regulates death receptor 5 and induces apoptosis through activation of the extrinsic pathway
-
LaVallee TM, Zhan XH, Johnson MS, Herbstritt CJ, Swartz G, Williams MS, Hembrough WA, Green SJ, Pribluda VS: 2-Methoxyestradiol up-regulates death receptor 5 and induces apoptosis through activation of the extrinsic pathway. Cancer Res 2003; 63: S468-S475. (Pubitemid 36152509)
-
(2003)
Cancer Research
, vol.63
, Issue.2
, pp. 468-475
-
-
Lavallee, T.M.1
Zhan, X.H.2
Johnson, M.S.3
Herbstritt, C.J.4
Swartz, G.5
Williams, M.S.6
Hembrough, W.A.7
Green, S.J.8
Pribluda, V.S.9
-
3
-
-
0037382060
-
Novel 2-methoxyestradiol analogues with antitumor activity
-
Tinley TL, Leal RM, Randall-Hulbek DA, Cessac JW, Wilkens LR, Rao PN, Mooberry SL: Novel 2-methoxyestradiol analogues with antitumor activity. Cancer Res 2003; 63: 1538-1549. (Pubitemid 36373641)
-
(2003)
Cancer Research
, vol.63
, Issue.7
, pp. 1538-1549
-
-
Tinley, T.L.1
Leal, R.M.2
Randall-Hlubek, D.A.3
Cessac, J.W.4
Wilkens, L.R.5
Rao, P.N.6
Mooberry, S.L.7
-
4
-
-
10744231706
-
2ME2 inhibits tumor growth and angiogenesis by disrupting microtubules and dysregulating HIF
-
DOI 10.1016/S1535-6108(03)00077-1, PII S1535610803000771
-
Mabjeesh NJ, Escuin D, La Vallee TM, Pribluda VS, Swartz GM, Johnson MS, Willard MT, Zhong H, Simons JW, Giannakakou P: 2ME2 inhibits tumor growth and angiogenesis by disrupting microtubules and dysregulating HIF. Cancer Cell 2003; 3: 363-373. (Pubitemid 38340305)
-
(2003)
Cancer Cell
, vol.3
, Issue.4
, pp. 363-375
-
-
Mabjeesh, N.J.1
Escuin, D.2
Lavallee, T.M.3
Pribluda, V.S.4
Swartz, G.M.5
Johnson, M.S.6
Willard, M.T.7
Zhong, H.8
Simons, J.W.9
Giannakakou, P.10
-
5
-
-
0034283773
-
Comparison of 2-methoxyestradiol-induced, doxetaxel-induced, and paclitaxel-induced apoptosis in hepatoma cells and its correlation with reactive oxygen species
-
Lin HL, Liu TY, Chau GY, Lui WY, Chi CW: Comparison of 2-methoxyestradiol-induced, doxetaxel-induced, and paclitaxel-induced apoptosis in hepatoma cells and its correlation with reactive oxygen species. Cancer 2000; 89: 983-994.
-
(2000)
Cancer
, vol.89
, pp. 983-994
-
-
Lin, H.L.1
Liu, T.Y.2
Chau, G.Y.3
Lui, W.Y.4
Chi, C.W.5
-
6
-
-
58049202339
-
2-Methoxyestradiol and multidrug resistance: Can 2-methoxyestradiol chemosensitize resistant breast cancer cells?
-
Azab SS, Salama SA, Abdel-Naim AB, Khalifa AE, El-Demerdash E, Al-Hendy A: 2-Methoxyestradiol and multidrug resistance: can 2-methoxyestradiol chemosensitize resistant breast cancer cells? Breast Cancer Res Treat 2009; 113: 9-19.
-
(2009)
Breast Cancer Res Treat
, vol.113
, pp. 9-19
-
-
Azab, S.S.1
Salama, S.A.2
Abdel-Naim, A.B.3
Khalifa, A.E.4
El-Demerdash, E.5
Al-Hendy, A.6
-
8
-
-
0037105379
-
2-Methoxyestradiol overcomes drug resistance in multiple myeloma cells
-
DOI 10.1182/blood-2002-02-0376
-
Chauhan D, Catley L, Hideshima T, Li G, Leblanc R, Gupta D, Sattler M, Richardson P, Schlossman RL, Podar K, Weller E, Munshi N, Anderson KC: 2-Methoxyestradiol overcomes drug resistance in multiple myeloma cells. Blood 2002; 100: 2187-2194. (Pubitemid 35001255)
-
(2002)
Blood
, vol.100
, Issue.6
, pp. 2187-2194
-
-
Chauhan, D.1
Catley, L.2
Hideshima, T.3
Li, G.4
Leblanc, R.5
Gupta, D.6
Sattler, M.7
Richardson, P.8
Schlossman, R.L.9
Podar, K.10
Weller, E.11
Munshi, N.12
Anderson, K.C.13
-
9
-
-
33750483598
-
Phase I safety, pharmacokinetic and pharmacodynamic studies of 2-methoxyestradiol alone or in combination with docetaxel in patients with locally recurrent or metastatic breast cancer
-
DOI 10.1007/s10637-006-9008-5
-
James J, Murry DL, Treston AM, Storniolo AM, Sledge GW, Sidor C, Miller KD: Phase I safety, pharmacokinetic and pharmacodynamic studies of 2-methoxyestradiol alone or in combination with docetaxel in patients with locally recurrent or metastatic breast cancer. Invest New Drugs 2006; 25: 41-48. (Pubitemid 44657641)
-
(2007)
Investigational New Drugs
, vol.25
, Issue.1
, pp. 41-48
-
-
James, J.1
Murry, D.J.2
Treston, A.M.3
Storniolo, A.M.4
Sledge, G.W.5
Sidor, C.6
Miller, K.D.7
-
10
-
-
35948946128
-
Novel therapy with 2-methoxyestradiol for the treatment of relapsed and plateau phase multiple myeloma
-
DOI 10.1158/1078-0432.CCR-07-0807
-
Rajkumar SV, Richardson PG, Lacy MQ, Dispenzieri A, Greipp PR, Witzig TE, Schlossman R, Sidor CF, Anderson KC, Gertz MA: Novel therapy with 2-methoxyestradiol for the treatment of relapsed and plateau phase multiple myeloma. Clin Cancer Res 2007; 13: 6162-6167. (Pubitemid 350075076)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.20
, pp. 6162-6167
-
-
Rajkumar, S.V.1
Richardson, P.G.2
Lacy, M.Q.3
Dispenzieri, A.4
Greipp, P.R.5
Witzig, T.E.6
Schlossman, R.7
Sidor, C.F.8
Anderson, K.C.9
Gertz, M.A.10
-
11
-
-
17044421361
-
Treatment modalities of hepatocellular carcinoma
-
Hung H: Treatment modalities of hepatocellular carcinoma. Curr Cancer Drug Targets 2005; 5: 131-138.
-
(2005)
Curr Cancer Drug Targets
, vol.5
, pp. 131-138
-
-
Hung, H.1
-
12
-
-
34547690632
-
Hypoxia and hepatocellular carcinoma: The therapeutic target for hepatocellular carcinoma
-
DOI 10.1111/j.1440-1746.2007.04997.x
-
Wu XZ, Xie GR, Chen D: Hypoxia and hepatocellular carcinoma: the therapeutic target for hepatocellular carcinoma. J Gastroenterol Hepatol 2007; 8: 1178-1182. (Pubitemid 47222667)
-
(2007)
Journal of Gastroenterology and Hepatology
, vol.22
, Issue.8
, pp. 1178-1182
-
-
Wu, X.-Z.1
Xie, G.-R.2
Chen, D.3
-
13
-
-
0036883658
-
MDR1 gene expression in hepatocellular carcinoma and the peritumoral liver of patients with and without cirrhosis
-
DOI 10.1016/S0304-3835(02)00155-6, PII S0304383502001556
-
Grude P, Conti F, Mennecier D, Louvel A, Houssin D, Weill B, Calmus Y: MDR1 gene expression in hepatocellular carcinoma and peritumoral liver of patients with and without cirrhosis. Cancer Lett 2002; 186: 107-113. (Pubitemid 35245333)
-
(2002)
Cancer Letters
, vol.186
, Issue.1
, pp. 107-113
-
-
Grude, P.1
Conti, F.2
Mennecier, D.3
Louvel, A.4
Houssin, D.5
Weill, B.6
Calmus, Y.7
-
14
-
-
3042761526
-
Angiogenesis in hepatocellular carcinoma: The retrospectives and perspectives
-
DOI 10.1007/s00432-003-0530-y
-
Sun HC, Tang ZY: Angiogenesis in hepatocellular carcinoma: the retrospectives and perspectives. J Cancer Res Clin Oncol 2004; 130: 307-319. (Pubitemid 38858340)
-
(2004)
Journal of Cancer Research and Clinical Oncology
, vol.130
, Issue.6
, pp. 307-319
-
-
Sun, H.-C.1
Tang, Z.-Y.2
-
15
-
-
33645092643
-
Hepatocyte growth factor and inducible nitric oxide synthase are involved in multidrug resistance-induced angiogenesis in hepatocellular carcinoma cell lines
-
Lasagna N, Fantappiè O, Solazzo M, Morbidelli L, Marchetti S, Cipriani G, Ziche M, Mazzanti R: Hepatocyte growth factor and inducible nitric oxide synthase are involved in multidrug resistance-induced angiogenesis in hepatocellular carcinoma cell lines. Cancer Res 2006; 66: 2673-2682.
-
(2006)
Cancer Res
, vol.66
, pp. 2673-2682
-
-
Lasagna, N.1
Fantappiè, O.2
Solazzo, M.3
Morbidelli, L.4
Marchetti, S.5
Cipriani, G.6
Ziche, M.7
Mazzanti, R.8
-
16
-
-
33646236421
-
A very low toxic agent induces apoptosis and reduces growth of human hepatocellular carcinoma cells
-
DOI 10.1111/j.1440-1746.2006.04327.x
-
Schumacher G, Scheunert S, Rueggeberg A, Bachem MG, Nussler AK, Spinelli A, Mukhopadhyay T, Prastschke J, Neuhaus P: A very low toxic agent induces apoptosis and reduces growth of human hepatocellular carcinoma cells. J Gastroenterol Hepatol 2006; 21: 1207-1212. (Pubitemid 43910016)
-
(2006)
Journal of Gastroenterology and Hepatology
, vol.21
, Issue.7
, pp. 1207-1212
-
-
Schumacher, G.1
Scheunert, S.2
Rueggeberg, A.3
Bachem, M.G.4
Nussler, A.K.5
Spinelli, A.6
Mukhopadhyay, T.7
Pratschke, J.8
Neuhaus, P.9
-
17
-
-
13944281987
-
Comparative effects of food-derived polyphenols on the viability and apoptosis of a human hepatoma cell line (HepG2)
-
DOI 10.1021/jf0490798
-
Ramos S, Alía M, Bravo L, Goya L: Comparative effects of food-derived polyphenols on the viability and apoptosis of a human hepatoma cell line (HepG2). J Agric Food Chem 2005; 53: 1271-1280. (Pubitemid 40270427)
-
(2005)
Journal of Agricultural and Food Chemistry
, vol.53
, Issue.4
, pp. 1271-1280
-
-
Ramos, S.1
Alia, M.2
Bravo, L.3
Goya, L.4
-
18
-
-
0025341331
-
New colorimetric cytotoxicity assay for anticancer-drug screening
-
Skehan P, Storeng R, Scudiero D, Monks A, McMahon J, Vistica D, Warren JT, Bokesch H, Kenney S, Boyd MR: New colorimetric cytotoxicity assay for anticancer drug screening. J Natl Cancer Inst 1990; 82: 1107-1112. (Pubitemid 20213250)
-
(1990)
Journal of the National Cancer Institute
, vol.82
, Issue.13
, pp. 1107-1112
-
-
Skehan, P.1
Storeng, R.2
Scudiero, D.3
Monks, A.4
McMahon, J.5
Vistica, D.6
Warren, J.T.7
Bokesch, H.8
Kenney, S.9
Boyd, M.R.10
-
19
-
-
0034945212
-
Reversal effects of nomegestrol acetate on multidrug resistance in adriamycin-resistant MCF7 breast cancer cell line
-
DOI 10.1186/bcr303
-
Li J, Xu L, He K, Guo W, Zheng Y, Xia P, Chen Y: Reversal effects on nomegestrol acetate on multi-drug resistance in adriamycin-resistant MCF-7 breast cancer cell line. Breast Cancer Res 2001; 3: 253-263. (Pubitemid 32633348)
-
(2001)
Breast Cancer Research
, vol.3
, Issue.4
, pp. 253-263
-
-
Li, J.1
Xu, L.-Z.2
He, K.-L.3
Guo, W.-J.4
Zheng, Y.-H.5
Xia, P.6
Chen, Y.7
-
20
-
-
3042740431
-
Mechanism of apoptosis induced by S100A8/A9 in colon cancer cell lines: The role of ROS and the effect of metal ions
-
DOI 10.1189/jlb.0903435
-
Ghavami S, Kerkhoff C, Los M, Hashemi M, Sorg C, Karami-Tehrani F: Mechanism of apoptosis induced by S100A8/A9 in colon cancer cell lines: the role of ROS and the effect of metal ions. J Leukoc Biol 2004; 76: 169-175. (Pubitemid 38857184)
-
(2004)
Journal of Leukocyte Biology
, vol.76
, Issue.1
, pp. 169-175
-
-
Ghavami, S.1
Kerkhoff, C.2
Los, M.3
Hashemi, M.4
Sorg, C.5
Karami-Tehrani, F.6
-
21
-
-
0028625746
-
A rapid and simple method for the isolation of apoptotic DNA fragments
-
Herrmann M, Lorenz HM, Voll R, Grunke M, Woith W, Kalden JR: A rapid and simple method for the isolation of apoptotic DNA fragments. Nucleic Acid Res 1994; 2: 5506-5507.
-
(1994)
Nucleic Acid Res
, vol.2
, pp. 5506-5507
-
-
Herrmann, M.1
Lorenz, H.M.2
Voll, R.3
Grunke, M.4
Woith, W.5
Kalden, J.R.6
-
22
-
-
1842430782
-
Effects of PI3K and p42/p44 MAPK on overexpression of vascular endothelial growth factor in hepatocellular carcinoma
-
Huang GW, Yang LY, Lu WQ: Effects of P13K and p42/p44 MAPK on overexpression of vascular endothelial growth factor in hepatocellular carcinoma. World J Gastroenterol 2004; 10: 809-812. (Pubitemid 38418351)
-
(2004)
World Journal of Gastroenterology
, vol.10
, Issue.6
, pp. 809-812
-
-
Huang, G.-W.1
Yang, L.-Y.2
Lu, W.-Q.3
-
24
-
-
0013449549
-
Cell cycle block and apoptosis induction in a human melanoma cell line following treatment with 2-methoxyestradiol: Therapeutic implications?
-
Ghosh R, Ott AM, Seetharam D, Slaga TJ, Kumar AP: Cell cycle block and apoptosis induction in a human melanoma cell line following treatment with 2-methoxyestradiol: therapeutic implications? Melanoma Res 2003; 13: 119-127.
-
(2003)
Melanoma Res
, vol.13
, pp. 119-127
-
-
Ghosh, R.1
Ott, A.M.2
Seetharam, D.3
Slaga, T.J.4
Kumar, A.P.5
-
25
-
-
49749142056
-
2-Methoxyestradiol inhibits hepatocellular carcinoma cell growth by inhibiting Cdc25 and inducing cell cycle arrest and apoptosis
-
Kar S, Wang M, Car BI: 2-Methoxyestradiol inhibits hepatocellular carcinoma cell growth by inhibiting Cdc25 and inducing cell cycle arrest and apoptosis. Cancer Chemother Pharmacol 2008; 62: 831-840.
-
(2008)
Cancer Chemother Pharmacol
, vol.62
, pp. 831-840
-
-
Kar, S.1
Wang, M.2
Car, B.I.3
-
27
-
-
2142761525
-
Concentration-dependent mitogenic and antiproliferative actions of 2-methoxyestradiol in estrogen receptor-positive human breast cancer cells
-
DOI 10.1016/j.jsbmb.2003.12.003, PII S0960076004000196
-
Liu ZJ, Zhu BT: Concentration-dependent mitogenic and antiproliferative actions of 2-methoxyestradiol in estrogen receptor-positive human breast cancer cells. J Steroid Biochem Mol Biol 2004; 88: 265-275. (Pubitemid 38553758)
-
(2004)
Journal of Steroid Biochemistry and Molecular Biology
, vol.88
, Issue.3
, pp. 265-275
-
-
Liu, Z.-J.1
Zhu, B.T.2
-
28
-
-
0038407728
-
Methoxyestrogens exert feedback inhibition on cytochrome P450 1A1 and 1B1
-
Dawling S, Roodi N, Parl FF: Methoxyestrogens exert feedback inhibition on cytochrome P450 1A1 and 1B1. Cancer Res 2003; 63: 3127-3132. (Pubitemid 36735863)
-
(2003)
Cancer Research
, vol.63
, Issue.12
, pp. 3127-3132
-
-
Dawling, S.1
Roodi, N.2
Parl, F.F.3
-
29
-
-
0344923319
-
Effect of 2-methoxyestradiol on the growth of methyl-nitroso-urea (MNU)-induced rat mammary carcinoma
-
DOI 10.1016/S0960-0760(02)00268-6
-
Lippert TH, Adlercreutz H, Berger MR, Seeger H, Elger W, Mueck AO: Effect of 2- methoxyestradiol on the growth of methylnitroso- urea (MNU)-induced rat mammary carcinoma. J Steroid Biochem Mol Biol 2003; 84: 51-56. (Pubitemid 36324437)
-
(2003)
Journal of Steroid Biochemistry and Molecular Biology
, vol.84
, Issue.1
, pp. 51-56
-
-
Lippert, T.H.1
Adlercreutz, H.2
Berger, M.R.3
Seeger, H.4
Elger, W.5
Mueck, A.O.6
-
30
-
-
0036645421
-
2-Methoxyestradiol inhibits proliferation and induces apoptosis independently of estrogen receptors α and β
-
LaVallee TM, Zhan XH, Herbstritt CJ, Kough E, Green SJ, Pribluda VS: 2-Methoxyestradiol inhibits proliferation and induces apoptosis independently of estrogen receptors α and β . Cancer Res 2002; 62: 3691-3697.
-
(2002)
Cancer Res
, vol.62
, pp. 3691-3697
-
-
Lavallee, T.M.1
Zhan, X.H.2
Herbstritt, C.J.3
Kough, E.4
Green, S.J.5
Pribluda, V.S.6
-
31
-
-
0034699513
-
Superoxide dismutase as a target for the selective killing of cancer cells
-
DOI 10.1038/35030140
-
Huang P, Feng L, Oldham EA, Keating MJ, Plunkett W: Superoxide dismutase as a target for the selective killing of cancer cells. Nature 2000; 407: 390-395. (Pubitemid 30736017)
-
(2000)
Nature
, vol.407
, Issue.6802
, pp. 390-395
-
-
Huang, P.1
Feng, L.2
Oldham, E.A.3
Keating, M.J.4
Plunkett, W.5
-
32
-
-
11144239579
-
2-Methoxyestradiol inhibits hypoxia-inducible factor 1α, tumor growth, and angiogenesis and augments efficacy in head and neck squamous cell carcinoma
-
Ricker JL, Chen Z, Yang XP, Pribluda VS, Swartz GM, Waes CV: 2-Methoxyestradiol inhibits hypoxia-inducible factor 1α , tumor growth, and angiogenesis and augments efficacy in head and neck squamous cell carcinoma. Clin Cancer Res 2004; 10: 8665-8673.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 8665-8673
-
-
Ricker, J.L.1
Chen, Z.2
Yang, X.P.3
Pribluda, V.S.4
Swartz, G.M.5
Waes, C.V.6
-
33
-
-
0038719671
-
JNK-dependent release of mitochondrial protein, Smac, during apoptosis in multiple myeloma (MM) cells
-
DOI 10.1074/jbc.C300076200
-
Chauhan D, Li G, Hideshima T, Podar K, Mitsiades C, Mitsiades N, Munshi N, Kharbanda S, Anderson KC: JNK-dependent release of mitochondrial protein, Smac, during apoptosis in multiple myeloma (MM) cells. J Biol Chem 2003; 278: 17593-17596. (Pubitemid 36799359)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.20
, pp. 17593-17596
-
-
Chauhan, D.1
Li, G.2
Hideshima, T.3
Podar, K.4
Mitsiades, C.5
Mitsiades, N.6
Munshi, N.7
Kharbanda, S.8
Anderson, K.C.9
-
34
-
-
0345258488
-
2-Methoxyestradiol exhibits a biphasic effect on VEGF-A in tumor cells and upregulation is mediated through ER-α: A possible signaling pathway associated with the impact of 2-ME2 on proliferative cells
-
Banerjee SN, Sengputa K, Banerjee S, Saxena NK, Banerjee SK: 2-Methoxyestradiol exhibits a biphasic effect on VEGF-A in tumor cells and upregulation is mediated through ER-α : a possible signaling pathway associated with the impact of 2-ME2 on proliferative cells. Neoplasia 2003; 5: 417-426.
-
(2003)
Neoplasia
, vol.5
, pp. 417-426
-
-
Banerjee, S.N.1
Sengputa, K.2
Banerjee, S.3
Saxena, N.K.4
Banerjee, S.K.5
|