Inhibin A and B in vitro bioactivities are modified by their degree of glycosylation and their affinities to betaglycan

Endocrinology

Volumn 148, Issue 5, 2007, Pages 2309-2316

  Makanji, Yogeshwar ^a   Harrison, Craig A ^a   Stanton, Peter G ^a   Krishna, Radha ^b   Robertson, David M ^a,c  

^a MONASH UNIVERSITY   (Australia)

^b Beckman Coulter Inc   (United States)

^c HUDSON INSTITUTE OF MEDICAL RESEARCH   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GLYCAN; FOLLITROPIN; GLYCAN DERIVATIVE; INHIBIN A; INHIBIN B; ISOPROTEIN; UNCLASSIFIED DRUG; BETAGLYCAN; INHIBIN; PROTEOGLYCAN; RECOMBINANT PROTEIN; TRANSFORMING GROWTH FACTOR BETA RECEPTOR;

ALPHA CHAIN; ANIMAL CELL; ARTICLE; BINDING AFFINITY; BIOLOGICAL ACTIVITY; CELL CULTURE; CONTROLLED STUDY; FOLLITROPIN RELEASE; GLYCOSYLATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYPOPHYSIS CELL; IMMUNOAFFINITY CHROMATOGRAPHY; IMMUNOASSAY; IMMUNOREACTIVITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INTERACTION; RAT; ANIMAL; CELL STRAIN COS1; CERCOPITHECUS; CHEMISTRY; CHO CELL; CRICETULUS; CYTOLOGY; GENETIC TRANSFECTION; GENETICS; HAMSTER; HUMAN; HYPOPHYSIS; IN VITRO STUDY; ISOLATION AND PURIFICATION; ISOMERISM; METABOLISM; PROTEIN BINDING;

ANIMALS; CERCOPITHECUS AETHIOPS; CHO CELLS; COS CELLS; CRICETINAE; CRICETULUS; FOLLICLE STIMULATING HORMONE; GLYCOSYLATION; HUMANS; INHIBINS; ISOMERISM; PITUITARY GLAND; PROTEIN BINDING; PROTEOGLYCANS; RATS; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; RECOMBINANT PROTEINS; TRANSFECTION;

EID: 34249807636     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2006-1612     Document Type: Article

References (38)

1. Shi Y, Massague J 2003 Mechanisms of TGF-β signaling from cell membrane to the nucleus. Cell 113:685-700
2. Mason AJ, Hayflick JS, Ling N, Esch F, Ueno N, Ying SY, Guillemin R, Niall H, Seeburg PH 1985 Complementary DNA sequences of ovarian follicular fluid inhibin show precursor structure and homology with transforming growth factor-β. Nature 318:659-663
3. Findlay JK 1993 An update on the roles of inhibin, activin, and follistatin as local regulators of folliculogenesis. Biol Reprod 48:15-23
4. Magoffin DA, Jakimiuk AJ 1997 Inhibin A, inhibin B and activin A in the follicular fluid of regularly cycling women. Hum Reprod 12:1714-1719
5. Robertson DM, Giacometti MS, de Kretser DM 1986 The effects of inhibin purified from bovine follicular fluid in several in vitro pituitary cell culture systems. Mol Cell Endocrinol 46:29-36
6. Woodruff TK, Krummen LA, Lyon RJ, Stocks DL, Mather JP 1993 Recombinant human inhibin A and recombinant human activin A regulate pituitary and ovarian function in the adult female rat. Endocrinology 132:2332-2341
7. Welt CK, Schneyer AL 2001 Differential regulation of inhibin B and inhibin a by follicle-stimulating hormone and local growth factors in human granulosa cells from small antral follicles. J Clin Endocrinol Metab 86:330-336
8. Welt CK, Adams JM, Sluss PM, Hall JE 1999 Inhibin A and inhibin B responses to gonadotropin withdrawal depends on stage of follicle development. J Clin Endocrinol Metab 84:2163-2169
9. Marchetti C, Hamdane M, Mitchell V, Mayo K, Devisme L, Rigot JM, Beauvillain JC, Hermand E, Defossez A 2003 Immunolocalization of inhibin and activin α and βB subunits and expression of corresponding messenger RNAs in the human adult testis. Biol Reprod 68:230-235
10. McNeilly AS, Souza CJ, Baird DT, Swanston IA, McVerry J, Crawford J, Cranfield M, Lincoln GA 2002 Production of inhibin A not B in rams: changes in plasma inhibin A during testis growth, and expression of inhibin/activin subunit mRNA and protein in adult testis. Reproduction 123:827-835
11. Wiater E, Vale W 2003 Inhibin is an antagonist of bone morphogenetic protein signaling. J Biol Chem 278:7934-7941
12. Lewis KA, Gray PC, Blount AL, MacConell LA, Wiater E, Bilezikjian LM, Vale W 2000 Betaglycan binds inhibin and can mediate functional antagonism of activin signalling. Nature 404:411-414
13. Chapman SC, Bernard DJ, Jelen J, Woodruff TK 2002 Properties of inhibin binding to betaglycan, InhBP/p120 and the activin type II receptors. Mol Cell Endocrinol 196:79-93
14. Harrison CA, Farnworth PG, Chan KL, Stanton PG, Ooi GT, Findlay JK, Robertson DM 2001 Identification of specific inhibin A-binding proteins on mouse Leydig (TM3) and Sertoli (TM4) cell lines. Endocrinology 142:1393-1402
15. Farnworth PG, Harrison CA, Leembruggen P, Chan KL, Stanton PG, Ooi GT, Rahman NA, Huhtaniemi IT, Findlay JK, Robertson DM 2001 Inhibin binding sites and proteins in pituitary, gonadal, adrenal and bone cells. Mol Cell Endocrinol 180:63-71
16. Wiater E, Harrison CA, Lewis KA, Gray PC, Vale WW 2006 Identification of distinct inhibin and transforming growth factor β-binding sites on betaglycan: functional separation of betaglycan co-receptor actions. J Biol Chem 281:17011-17022
17. Mayo KE, Cerelli GM, Spiess J, Rivier J, Rosenfeld MG, Evans RM, Vale W 1986 Inhibin A-subunit cDNAs from porcine ovary and human placenta. Proc Natl Acad Sci USA 83:5849-5853
18. Tierney ML, Goss NH, Tomkins SM, Kerr DB, Pitt DE, Forage RG, Robertson DM, Hearn MT, de Kretser DM 1990 Physicochemical and biological characterization of recombinant human inhibin A. Endocrinology 126:3268-3270
19. Mason AJ, Farnworth PG, Sullivan J 1996 Characterization and determination of the biological activities of noncleavable high molecular weight forms of inhibin A and activin A. Mol Endocrinol 10:1055-1065
20. Rose MP, Gaines Das RE 1996 International collaborative study by in vitro bioassays and immunoassays of the First International Standard for Inhibin, Human Recombinant. Biologicals 24:1-18
21. Scott RS, Burger HG, Quigg H 1980 A simple and rapid in vitro bioassay for inhibin. Endocrinology 107:1536-1542
22. van Casteren JI, Schoonen WG, Kloosterboer HJ 2000 Development of time-resolved immunofluorometric assays for rat follicle-stimulating hormone and luteinizing hormone and application on sera of cycling rats. Biol Reprod 62:886-894
23. Finney DJ 1971 Statistical method in biological assay. 2nd ed. London: Charles Griffin
24. Robertson DM, Stephenson T, Pruysers E, McCloud P, Tsigos A, Groome N, Mamers P, Burger HG 2002 Characterization of inhibin forms and their measurement by an inhibin α-subunit ELISA in serum from postmenopausal women with ovarian cancer. J Clin Endocrinol Metab 87:816-824
25. Robertson DM, Cahir N, Findlay JK, Burger HG, Groome N 1997 The biological and immunological characterization of inhibin A and B forms in human follicular fluid and plasma. J Clin Endocrinol Metab 82:889-896
26. Robertson D, Burger HG, Sullivan J, Cahir N, Groome N, Poncelet E, Franchimont P, Woodruff T, Mather JP 1996 Biological and immunological characterization of inhibin forms in human plasma. J Clin Endocrinol Metab 81:669-676
27. Grinyer J, McKay M, Nevalainen H, Herbert BR 2004 Fungal proteomics: initial mapping of biological control strain Trichoderma harzianum. Curr Genet 45:163-169
28. Hertan R, Farnworth PG, Fitzsimmons KL, Robertson DM 1999 Identification of high affinity binding sites for inhibin on ovine pituitary cells in culture. Endocrinology 140:6-12
29. Ling N, Ying SY, Ueno N, Shimasaki S, Esch F, Hotta M, Guillemin R 1986 Pituitary FSH is released by a heterodimer of the β-subunits from the two forms of inhibin. Nature 321:779-782
30. Mason AJ, Berkemeier LM, Schmelzer CH, Schwall RH 1989 Activin B: precursor sequences, genomic structure and in vitro activities. Mol Endocrinol 3:1352-1358
31. Ying SY, Czvik J, Becker A, Ling N, Ueno N, Guillemin R 1987 Secretion of follicle-stimulating hormone and production of inhibin are reciprocally related. Proc Natl Acad Sci USA 84:4631-4635
32. McLachlan RI, Robertson DM, Burger HG, de Kretser DM 1986 The radioimmunoassay of bovine and human follicular fluid and serum inhibin. Mol Cell Endocrinol 46:175-185
33. Ulloa F, Real FX 2001 Differential distribution of sialic acid in α2,3 and α2,6 linkages in the apical membrane of cultured epithelial cells and tissues. J Histochem Cytochem 49:501-510
34. Stanton PG, Burgon PG, Hearn MT, Robertson DM 1996 Structural and functional characterisation of hFSH and hLH isoforms. Mol Cell Endocrinol 125:133-141
35. Matzuk MM, Finegold MJ, Su JG, Hsueh AJ, Bradley A 1992 α-Inhibin is a tumour-suppressor gene with gonadal specificity in mice. Nature 360:313-319
36. Shelling AN, Burton KA, Chand AL, van Ee CC, France JT, Farquhar CM, Milsom SR, Love DR, Gersak K, Aittomaki K, Winship IM 2000 Inhibin: a candidate gene for premature ovarian failure. Hum Reprod 15:2644-2649
37. Thirunavukarasu P, Stephenson T, Forray J, Stanton PG, Groome N, Wallace E, Robertson DM 2001 Changes in molecular weight forms of inhibin A and pro-αC in maternal serum during human pregnancy. J Clin Endocrinol Metab 86:5794-5804
38. Hasegawa Y, Miyamoto K, Sugino H, Takio K, Inoue M, Ibuki Y 1994 Progress with human and rat inhibin characterization. In: Frontiers in endocrinology: inhibin and inhibin-related proteins. Rome: Ares-Serono Symposia; 5-24