메뉴 건너뛰기




Volumn 19, Issue 5, 2009, Pages 413-423

Improved spatial learning in aged rats by genetic activation of protein kinase C in small groups of hippocampal neurons

Author keywords

Aged rats; Dentate granule neurons; Herpes simplex virus vector; Protein kinase C; Spatial discrimination

Indexed keywords

PROTEIN KINASE C;

EID: 66049123115     PISSN: 10509631     EISSN: 10981063     Source Type: Journal    
DOI: 10.1002/hipo.20506     Document Type: Article
Times cited : (29)

References (76)
  • 1
    • 0027745596 scopus 로고
    • Modified hippocampal long-term potentiation in PKC-mutant mice
    • DOI 10.1016/0092-8674(93)90613-U
    • Abeliovich A, Chen C, Goda Y, Silva AJ, Stevens CF, Tonegawa S. 1993a. Modified hippocampal long-term potentiation in PKC gamma-mutant mice. Cell 75:1253-1262. (Pubitemid 24021901)
    • (1993) Cell , vol.75 , Issue.7 , pp. 1253-1262
    • Abeliovich, A.1    Chen, C.2    Goda, Y.3    Silva, A.J.4    Stevens, C.F.5    Tonegawa, S.6
  • 2
    • 0027787664 scopus 로고
    • PKCgamma mutant mice exhibit mild deficits in spatial and contextual learning
    • Abeliovich A, Paylor R, Chen C, Kim JJ, Wehner JM, Tonegawa S. 1993b. PKC gamma mutant mice exhibit mild deficits in spatial and contextual learning. Cell 75:1263-1271. (Pubitemid 2029892)
    • (1993) Cell , vol.75 , Issue.7 , pp. 1263-1271
    • Abeliovich, A.1    Paylor, R.2    Chen Chong3    Kim, J.J.4    Wehner, J.M.5    Tonegawa, S.6
  • 3
    • 0032837892 scopus 로고    scopus 로고
    • The effects of nicotine on learning and memory: A neuropsychological assessment in young and senescent Fischer 344 rats
    • DOI 10.1016/S0031-9384(99)00081-5, PII S0031938499000815
    • Attaway CM, Compton DM, Turner MD. 1999. The effects of nicotine on learning and memory: A neuropsychological assessment in young and senescent Fischer 344 rats. Physiol Behav 67:421-431. (Pubitemid 29469547)
    • (1999) Physiology and Behavior , vol.67 , Issue.3 , pp. 421-431
    • Attaway, C.M.1    Compton, D.M.2    Turner, M.D.3
  • 5
    • 0030813899 scopus 로고    scopus 로고
    • The role of anchoring protein RACKI in PCK activation in the ageing rat brain
    • DOI 10.1016/S0166-2236(97)01084-9
    • Battaini F, Pascale A, Paoletti R, Govoni S. 1997. The role of anchoring protein RACK1 in PKC activation in the ageing rat brain. Trends Neurosci 20:410-415. (Pubitemid 27364512)
    • (1997) Trends in Neurosciences , vol.20 , Issue.9 , pp. 410-415
    • Battaini, F.1    Pascale, A.2    Paoletti, R.3    Govoni, S.4
  • 6
    • 0032865258 scopus 로고    scopus 로고
    • Protein kinase C anchoring deficit in postmortem brains of Alzheimer's disease patients
    • DOI 10.1006/exnr.1999.7151
    • Battaini F, Pascale A, Lucchi L, Pasinetti GM, Govoni S. 1999. Protein kinase C anchoring deficit in postmortem brains of Alzheimer's disease patients. Exp Neurol 159:559-564. (Pubitemid 29485243)
    • (1999) Experimental Neurology , vol.159 , Issue.2 , pp. 559-564
    • Battaini, F.1    Pascale, A.2    Lucchi, L.3    Pasinetti, G.M.4    Govoni, S.5
  • 7
    • 13844257516 scopus 로고    scopus 로고
    • Neurogenesis in a rat model of age-related cognitive decline
    • DOI 10.1111/j.1474-9728.2004.00099.x
    • Bizon JL, Lee HJ, Gallagher M. 2004. Neurogenesis in a rat model of age-related cognitive decline. Aging Cell 3:227-234. (Pubitemid 40246687)
    • (2004) Aging Cell , vol.3 , Issue.4 , pp. 227-234
    • Bizon, J.L.1    Lee, H.J.2    Gallagher, M.3
  • 8
    • 19444371789 scopus 로고    scopus 로고
    • Regulated lentiviral NGF gene transfer controls rescue of medial septal cholinergic neurons
    • DOI 10.1016/j.ymthe.2005.01.007, PII S152500160500016X
    • Blesch A, Conner J, Pfeifer A, Gasmi M, Ramirez A, Britton W, Alfa R, Verma I, Tuszynski MH. 2005. Regulated lentiviral NGF gene transfer controls rescue of medial septal cholinergic neurons. Mol Ther 11:916-925. (Pubitemid 40724110)
    • (2005) Molecular Therapy , vol.11 , Issue.6 , pp. 916-925
    • Blesch, A.1    Conner, J.2    Pfeifer, A.3    Gasmi, M.4    Ramirez, A.5    Britton, W.6    Alfa, R.7    Verma, I.8    Tuszynski, M.H.9
  • 9
    • 0021804749 scopus 로고
    • On the number of neurons in the dentate gyrus of the rat
    • DOI 10.1016/0006-8993(85)90257-4
    • Boss BD, Peterson GM, Cowan WM. 1985. On the number of neurons in the dentate gyrus of the rat. Brain Res 338:144-150. (Pubitemid 15012466)
    • (1985) Brain Research , vol.338 , Issue.1 , pp. 144-150
    • Boss, B.D.1    Peterson, G.M.2    Cowan, W.M.3
  • 10
    • 0037790709 scopus 로고    scopus 로고
    • Immune responses to replication-defective HSV-1 type vectors within the CNS: Implications for gene therapy
    • DOI 10.1038/sj.gt.3302047
    • Bowers WJ, Olschowka JA, Federoff HJ. 2003. Immune responses to replication-defective HSV-1 type vectors within the CNS: Implications for gene therapy. Gene Ther 10:941-945. (Pubitemid 36722428)
    • (2003) Gene Therapy , vol.10 , Issue.SPEC. , pp. 941-945
    • Bowers, W.J.1    Olschowka, J.A.2    Federoff, H.J.3
  • 11
    • 0025365940 scopus 로고
    • Opiate antagonists enhance the working memory of rats in the radial maze
    • DOI 10.1016/0091-3057(90)90250-L
    • Canli T, Cook RG, Miczek KA. 1990. Opiate antagonists enhance the working memory of rats in the radial maze. Pharmacol Biochem Behav 36:521-525. (Pubitemid 20223017)
    • (1990) Pharmacology Biochemistry and Behavior , vol.36 , Issue.3 , pp. 521-525
    • Canli, T.1    Cook, R.G.2    Miczek, K.A.3
  • 12
    • 0029620817 scopus 로고
    • Impaired motor coordination correlates with persistent multiple climbing fiber innervation in PKC mutant mice
    • DOI 10.1016/0092-8674(95)90148-5
    • Chen C, Kano M, Abeliovich A, Chen L, Bao S, Kim JJ, Hashimoto K, Thompson RF, Tonegawa S. 1995. Impaired motor coordination correlates with persistent multiple climbing fiber innervation in PKC gamma mutant mice. Cell 83:1233-1242. (Pubitemid 26007813)
    • (1995) Cell , vol.83 , Issue.7 , pp. 1233-1242
    • Chen, C.1    Kano, M.2    Abeliovich, A.3    Chen, L.4    Bao, S.5    Kim, J.J.6    Hashimoto, K.7    Thompson, R.F.8    Tonegawa, S.9
  • 13
    • 0028965223 scopus 로고
    • Somatic gene transfer of NGF to the aged brain: Behavioral and morphological amelioration
    • Chen KS, Gage FH. 1995. Somatic gene transfer of NGF to the aged brain: Behavioral and morphological amelioration. J Neurosci 15:2819-2825.
    • (1995) J Neurosci , vol.15 , pp. 2819-2825
    • Chen, K.S.1    Gage, F.H.2
  • 14
    • 0038518145 scopus 로고    scopus 로고
    • Requirement of AMPA receptor GluR2 phosphorylation for cerebellar long-term depression
    • DOI 10.1126/science.1082915
    • Chung HJ, Steinberg JP, Huganir RL, Linden DJ. 2003. Requirement of AMPA receptor GluR2 phosphorylation for cerebellar long-term depression. Science 300:1751-1755. (Pubitemid 36712572)
    • (2003) Science , vol.300 , Issue.5626 , pp. 1751-1755
    • Chung, H.J.1    Steinberg, J.P.2    Huganir, R.L.3    Linden, D.J.4
  • 15
    • 0036229301 scopus 로고    scopus 로고
    • Individual differences in spatial memory among aged rats are related to hippocampal PKC immunoreactivity
    • DOI 10.1002/hipo.10016
    • Colombo PJ, Gallagher M. 2002. Individual differences in spatial memory among aged rats are related to hippocampal PKCgamma immunoreactivity. Hippocampus 12:285-289. (Pubitemid 34436711)
    • (2002) Hippocampus , vol.12 , Issue.2 , pp. 285-289
    • Colombo, P.J.1    Gallagher, M.2
  • 18
    • 0036380845 scopus 로고    scopus 로고
    • Dissecting the effect of aging on the neural substrates of memory: Deterioration, preservation or functional reorganization?
    • Della-Maggiore V, Grady CL, McIntosh AR. 2002. Dissecting the effect of aging on the neural substrates of memory: Deterioration, preservation or functional reorganization? Rev Neurosci 13:167-181.
    • (2002) Rev Neurosci , vol.13 , pp. 167-181
    • Della-Maggiore, V.1    Grady, C.L.2    McIntosh3
  • 19
    • 0032562162 scopus 로고    scopus 로고
    • Hippocampal grafts of acetylcholine-producing cells are sufficient to improve behavioural performance following a unilateral fimbria-fornix lesion
    • DOI 10.1016/S0306-4522(97)00543-5, PII S0306452297005435
    • Dickinson-Anson H, Aubert I, Gage FH, Fisher LJ. 1998. Hippocampal grafts of acetylcholine-producing cells are sufficient to improve behavioural performance following a unilateral fimbria-fornix lesion. Neuroscience 84:771-781. (Pubitemid 28137893)
    • (1998) Neuroscience , vol.84 , Issue.3 , pp. 771-781
    • Dickinson-Anson, H.1    Aubert, I.2    Gage, F.H.3    Fisher, L.J.4
  • 21
  • 22
    • 0027177629 scopus 로고
    • Effects of aging on spatial learning and hippocampal protein kinase C in mice
    • DOI 10.1016/0197-4580(93)90116-S
    • Fordyce DE, Wehner JM. 1993. Effects of aging on spatial learning and hippocampal protein kinase C in mice. Neurobiol Aging 14:309-317. (Pubitemid 23214697)
    • (1993) Neurobiology of Aging , vol.14 , Issue.4 , pp. 309-317
    • Fordyce, D.E.1    Wehner, J.M.2
  • 23
    • 0029844849 scopus 로고    scopus 로고
    • Helper virus-free transfer of herpes simplex virus type 1 plasmid vectors into neural cells
    • Fraefel C, Song S, Lim F, Lang P, Yu L, Wang Y, Wild P, Geller AI. 1996. Helper virus-free transfer of herpes simplex virus type 1 plasmid vectors into neural cells. J Virol 70:7190-7197. (Pubitemid 26307436)
    • (1996) Journal of Virology , vol.70 , Issue.10 , pp. 7190-7197
    • Fraefel, C.1    Song, S.2    Lim, F.3    Lang, P.4    Yu, L.5    Wang, Y.6    Wild, P.7    Geller, A.I.8
  • 24
    • 0023784651 scopus 로고
    • A defective HSV-1 vector expresses Escherichia coli -galactosidase in cultured peripheral neurons
    • Geller AI, Breakefield XO. 1988. A defective HSV-1 vector expresses Escherichia coli beta-galactosidase in cultured peripheral neurons. Science 241:1667-1669. (Pubitemid 18238708)
    • (1988) Science , vol.241 , Issue.4873 , pp. 1667-1669
    • Geller, A.I.1    Breakefield, X.O.2
  • 25
    • 0023885305 scopus 로고
    • The protein kinase family: Conserved features and deduced phylogeny of the catalytic domains
    • Hanks SK, Quinn AM, Hunter T. 1988. The protein kinase family: Conserved features and deduced phylogeny of the catalytic domains. Science 241:42-52. (Pubitemid 18168114)
    • (1988) Science , vol.241 , Issue.4861 , pp. 42-52
    • Hanks, S.K.1    Quinn, A.M.2    Hunter, T.3
  • 27
    • 0141890287 scopus 로고    scopus 로고
    • Protein kinase M zeta synthesis from a brain mR.N.A encoding an independent protein kinase C zeta catalytic domain. Implications for the molecular mechanism of memory
    • Hernandez AI, Blace N, Crary JF, Serrano PA, Leitges M, Libien JM, Weinstein G, Tcherapanov A, Sacktor TC. 2003. Protein kinase M zeta synthesis from a brain mRNA encoding an independent protein kinase C zeta catalytic domain. Implications for the molecular mechanism of memory. J Biol Chem 278:40305-40316.
    • (2003) J Biol Chem , vol.278 , pp. 40305-40316
    • Hernandez, A.I.1    Blace, N.2    Crary, J.F.3    Serrano, P.A.4    Leitges, M.5    Libien, J.M.6    Weinstein, G.7    Tcherapanov, A.8    Sacktor, T.C.9
  • 28
    • 0019917243 scopus 로고
    • Molecular biology of learning: Modulation of transmitter release
    • Kandel ER, Schwartz JH. 1982. Molecular biology of learning: Modulation of transmitter release. Science 218:433-443.
    • (1982) Science , vol.218 , pp. 433-443
    • Kandel, E.R.1    Schwartz, J.H.2
  • 29
    • 0029591742 scopus 로고
    • Impaired synapse elimination during cerebellar development in PKC mutant mice
    • DOI 10.1016/0092-8674(95)90147-7
    • Kano M, Hashimoto K, Chen C, Abeliovich A, Aiba A, Kurihara H, Watanabe M, Inoue Y, Tonegawa S. 1995. Impaired synapse elimination during cerebellar development in PKC gamma mutant mice. Cell 83:1223-1231. (Pubitemid 26007812)
    • (1995) Cell , vol.83 , Issue.7 , pp. 1223-1231
    • Kano, M.1    Hashimoto, K.2    Chen, C.3    Abeliovich, A.4    Aiba, A.5    Kurihara, H.6    Watanabe, M.7    Inoue, Y.8    Tonegawa, S.9
  • 31
    • 0034284813 scopus 로고    scopus 로고
    • NGF gene transfer to intrinsic basal forebrain neurons increases cholinergic cell size and protects from age-related, spatial memory deficits in middle-aged rats
    • Klein RL, Hirko AC, Meyers CA, Grimes JR, Muzyczka N, Meyer EM. 2000. NGF gene transfer to intrinsic basal forebrain neurons increases cholinergic cell size and protects from age-related, spatial memory deficits in middle-aged rats. Brain Res 875:144-151.
    • (2000) Brain Res , vol.875 , pp. 144-151
    • Klein, R.L.1    Hirko, A.C.2    Meyers, C.A.3    Grimes, J.R.4    Muzyczka, N.5    Meyer, E.M.6
  • 33
    • 0033578855 scopus 로고    scopus 로고
    • Long-term potentiation-a decade of progress?
    • Malenka RC, Nicoll RA. 1999. Long-term potentiation-a decade of progress? Science 285:1870-1874.
    • (1999) Science , vol.285 , pp. 1870-1874
    • Malenka, R.C.1    Nicoll, R.A.2
  • 34
    • 0033044592 scopus 로고    scopus 로고
    • Nerve growth factor expressed in the medial septum following in vivo gene delivery using a recombinant adeno-associated viral vector protects cholinergic neurons from fimbria-fornix lesion-induced degeneration
    • DOI 10.1006/exnr.1998.6961
    • Mandel RJ, Gage FH, Clevenger DG, Spratt SK, Snyder RO, Leff SE. 1999. Nerve growth factor expressed in the medial septum following in vivo gene delivery using a recombinant adeno-associated viral vector protects cholinergic neurons from fimbria-fornix lesioninduced degeneration. Exp Neurol 155:59-64. (Pubitemid 29072605)
    • (1999) Experimental Neurology , vol.155 , Issue.1 , pp. 59-64
    • Mandel, R.J.1    Gage, F.H.2    Clevenger, D.G.3    Spratt, S.K.4    Snyder, R.O.5    Leff, S.E.6
  • 36
    • 0019957779 scopus 로고
    • Place navigation impaired in rats with hippocampal lesions
    • Morris RG, Garrud P, Rawlins JN, O'Keefe J. 1982. Place navigation impaired in rats with hippocampal lesions. Nature 297:681-683.
    • (1982) Nature , vol.297 , pp. 681-683
    • Morris, R.G.1    Garrud, P.2    Rawlins, J.N.3    O'Keefe, J.4
  • 38
    • 0035975648 scopus 로고    scopus 로고
    • Enhanced auditory reversal learning by genetic activation of protein kinase C in small groups of rat hippocampal neurons
    • DOI 10.1016/S0165-3806(01)00204-8, PII S0165380601002048
    • Neill JC, Sarkisian MR, Wang Y, Liu Z, Yu L, Tandon P, Zhang G, Holmes GL, Geller AI. 2001. Enhanced auditory reversal learning by genetic activation of protein kinase C in small groups of rat hippocampal neurons. Mol Brain Res 93:127-136. (Pubitemid 32925173)
    • (2001) Molecular Brain Research , vol.93 , Issue.2 , pp. 127-136
    • Neill, J.C.1    Sarkisian, M.R.2    Wang, Y.3    Liu, Z.4    Yu, L.5    Tandon, P.6    Zhang, G.-R.7    Holmes, G.L.8    Geller, A.I.9
  • 39
    • 0023139527 scopus 로고
    • Phorbol ester enhancement of neurotransmitter release from rat brain synaptosomes
    • DOI 10.1111/j.1471-4159.1987.tb04137.x
    • Nichols RA, Haycock JW, Wang JK, Greengard P. 1987. Phorbol ester enhancement of neurotransmitter release from rat brain synaptosomes. J Neurochem 48:615-621. (Pubitemid 17005176)
    • (1987) Journal of Neurochemistry , vol.48 , Issue.2 , pp. 615-621
    • Nichols, R.A.1    Haycock, J.W.2    Wang, J.K.T.3    Greengard, P.4
  • 40
    • 0033232920 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor-mediated hippocampal phosphoinositide turnover is blunted in spatial learning-impaired aged rats
    • Nicolle MM, Colombo PJ, Gallagher M, McKinney M. 1999. Metabotropic glutamate receptor-mediated hippocampal phosphoinositide turnover is blunted in spatial learning-impaired aged rats. J Neurosci 19:9604-9610. (Pubitemid 30228111)
    • (1999) Journal of Neuroscience , vol.19 , Issue.21 , pp. 9604-9610
    • Nicolle, M.M.1    Colombo, P.J.2    Gallagher, M.3    McKinney, M.4
  • 41
    • 0037414411 scopus 로고    scopus 로고
    • Gene transfer of constitutively active protein kinase C into striatal neurons accelerates onset of levodopa-induced motor response alterations in parkinsonian rats
    • DOI 10.1016/S0006-8993(03)02348-5
    • Oh JD, Geller AI, Zhang G, Chase TN. 2003. Gene transfer of constitutively active protein kinase C into striatal neurons accelerates onset of levodopa-induced motor response alterations in parkinsonian rats. Brain Res 971:18-30. (Pubitemid 36412060)
    • (2003) Brain Research , vol.971 , Issue.1 , pp. 18-30
    • Oh, J.D.1    Geller, A.I.2    Zhang, G.-R.3    Chase, T.N.4
  • 42
    • 0024423978 scopus 로고
    • Imaging of memory-specific changes in the distribution of protein kinase C in the hippocampus
    • Olds JL, Anderson ML, McPhie DL, Staten LD, Alkon DL. 1989. Imaging of memory-specific changes in the distribution of protein kinase C in the hippocampus. Science 245:866-869. (Pubitemid 19223666)
    • (1989) Science , vol.245 , Issue.4920 , pp. 866-869
    • Olds, J.L.1    Anderson, M.L.2    McPhie, D.L.3    Staten, L.D.4    Alkon, D.L.5
  • 43
    • 0025514412 scopus 로고
    • Discrimination learning alters the distribution of protein kinase C in the hippocampus of rats
    • Olds JL, Golski S, McPhie DL, Olton D, Mishkin M, Alkon DL. 1990. Discrimination learning alters the distribution of protein kinase C in the hippocampus of rats. J Neurosci 10:3707-3713.
    • (1990) J Neurosci , vol.10 , pp. 3707-3713
    • Olds, J.L.1    Golski, S.2    McPhie, D.L.3    Olton, D.4    Mishkin, M.5    Alkon, D.L.6
  • 45
    • 0029851919 scopus 로고    scopus 로고
    • Functional impairment in protein kinase C by RACK1 (receptor for activated C kinase 1) deficiency in aged rat brain cortex
    • Pascale A, Fortino I, Govoni S, Trabucchi M, Wetsel WC, Battaini F. 1996. Functional impairment in protein kinase C by RACK1 (receptor for activated C kinase 1) deficiency in aged rat brain cortex. J Neurochem 67:2471-2477. (Pubitemid 26392518)
    • (1996) Journal of Neurochemistry , vol.67 , Issue.6 , pp. 2471-2477
    • Pascale, A.1    Fortino, I.2    Govoni, S.3    Trabucchi, M.4    Wetsel, W.C.5    Battaini, F.6
  • 46
    • 33748049463 scopus 로고    scopus 로고
    • Storage of spatial information by the maintenance mechanism of LTP
    • DOI 10.1126/science.1128657
    • Pastalkova E, Serrano P, Pinkhasova D, Wallace E, Fenton AA, Sacktor TC. 2006. Storage of spatial information by the maintenance mechanism of LTP. Science 313:1141-1144. (Pubitemid 44300243)
    • (2006) Science , vol.313 , Issue.5790 , pp. 1141-1444
    • Pastalkova, E.1    Serrano, P.2    Pinkhasova, D.3    Wallace, E.4    Fenton, A.A.5    Sacktor, T.C.6
  • 48
    • 0028030068 scopus 로고
    • Autonomously active protein kinase C in the maintenance phase of N-methyl-D-aspartate receptor-independent long term potentiation
    • Powell CM, Johnston D, Sweatt JD. 1994. Autonomously active protein kinase C in the maintenance phase of N-methyl-D-aspartate receptor-independent long term potentiation. J Biol Chem 269: 27958-27963. (Pubitemid 24982995)
    • (1994) Journal of Biological Chemistry , vol.269 , Issue.45 , pp. 27958-27963
    • Powell, C.M.1    Johnston, D.2    Sweatt, J.D.3
  • 50
    • 0037936789 scopus 로고    scopus 로고
    • Impact of aging on hippocampal function: Plasticity, network dynamics, and cognition
    • DOI 10.1016/S0301-0082(02)00126-0
    • Rosenzweig ES, Barnes CA. 2003. Impact of aging on hippocampal function: Plasticity, network dynamics, and cognition. Prog Neurobiol 69:143-179. (Pubitemid 36577321)
    • (2003) Progress in Neurobiology , vol.69 , Issue.3 , pp. 143-179
    • Rosenzweig, E.S.1    Barnes, C.A.2
  • 52
    • 0035474310 scopus 로고    scopus 로고
    • Adaptor proteins in protein kinase C-mediated signal transduction
    • DOI 10.1038/sj.onc.1204778
    • Schechtman D, Mochly-Rosen D. 2001. Adaptor proteins in protein kinase C-mediated signal transduction. Oncogene 20:6339-6347. (Pubitemid 32977843)
    • (2001) Oncogene , vol.20 , Issue.REV. ISS. 5 , pp. 6339-6347
    • Schechtman, D.1    Mochly-Rosen, D.2
  • 53
    • 0141919571 scopus 로고    scopus 로고
    • Glutamate receptor subunit 2 serine 880 phosphorylation modulates synaptic transmission and mediates plasticity in CA1 pyramidal cells
    • Seidenman KJ, Steinberg JP, Huganir R, Malinow R. 2003. Glutamate receptor subunit 2 Serine 880 phosphorylation modulates synaptic transmission and mediates plasticity in CA1 pyramidal cells. J Neurosci 23:9220-9228. (Pubitemid 37243823)
    • (2003) Journal of Neuroscience , vol.23 , Issue.27 , pp. 9220-9228
    • Seidenman, K.J.1    Steinberg, J.P.2    Huganir, R.3    Malinow, R.4
  • 54
    • 34548125816 scopus 로고    scopus 로고
    • Rapid erasure of long-term memory associations in the cortex by an inhibitor of PKM
    • DOI 10.1126/science.1144334
    • Shema R, Sacktor TC, Dudai Y. 2007. Rapid erasure of long-term memory associations in the cortex by an inhibitor of PKM zeta. Science 317:951-953. (Pubitemid 47301323)
    • (2007) Science , vol.317 , Issue.5840 , pp. 951-953
    • Shema, R.1    Sacktor, T.C.2    Dudai, Y.3
  • 55
    • 0026547375 scopus 로고
    • Evidence that the herpes simplex virus immediate early protein ICP27 acts posttranscriptionally during infection to regulate gene expression
    • Smith IL, Hardwicke MA, Sandri-Goldin RM. 1992. Evidence that the herpes simplex virus immediate early protein ICP27 acts posttranscriptionally during infection to regulate gene expression. Virology 186:74-86.
    • (1992) Virology , vol.186 , pp. 74-86
    • Smith, I.L.1    Hardwicke, M.A.2    Sandri-Goldin, R.M.3
  • 57
    • 0033543074 scopus 로고    scopus 로고
    • Improved titers for helper virus-free herpes simplex virus type 1 plasmid vectors by optimization of the packaging protocol and addition of noninfectious herpes simplex virus-related particles (previral DNA replication enveloped particles) to the packaging procedure
    • DOI 10.1089/10430349950017365
    • Sun M, Zhang GR, Yang T, Yu L, Geller AI. 1999. Improved titers for helper virus-free herpes simplex virus type 1 plasmid vectors by optimization of the packaging protocol and addition of noninfectious herpes simplex virus-related particles (previral DNA replication enveloped particles) to the packaging procedure. Hum Gene Ther 10:2005-2011. (Pubitemid 29387914)
    • (1999) Human Gene Therapy , vol.10 , Issue.12 , pp. 2005-2011
    • Sun, M.1    Zhang, G.-R.2    Yang, T.3    Yu, L.4    Geller, A.I.5
  • 58
    • 0037456986 scopus 로고    scopus 로고
    • Correction of a rat model of Parkinson's disease by coexpression of tyrosine hydroxylase and aromatic amino acid decarboxylase from a helper virus-free herpes simplex virus type 1 vector
    • DOI 10.1089/104303403321467180
    • Sun M, Zhang G, Kong L, Holmes C, Wang X, Zhang W, Goldstein DS, Geller AI. 2003. Correction of a rat model of Parkinson's disease by coexpression of tyrosine hydroxylase and aromatic amino acid decarboxylase from a helper virus-free herpes simplex virus type 1 vector. Hum Gene Ther 14:415-424. (Pubitemid 36403534)
    • (2003) Human Gene Therapy , vol.14 , Issue.5 , pp. 415-424
    • Sun, M.1    Zhang, G.-R.2    Kong, L.3    Holmes, C.4    Wang, X.5    Zhang, W.6    Goldstein, D.S.7    Geller, A.I.8
  • 59
    • 11144245251 scopus 로고    scopus 로고
    • Coexpression of tyrosine hydroxylase, GTP cyclohydrolase I, aromatic amino acid decarboxylase, and vesicular monoamine transporter 2 from a helper virus-free herpes simplex virus type 1 vector supports high-level, long-term biochemical and behavioral correction of a rat model of Parkinson's disease
    • Sun M, Kong L, Wang X, Holmes C, Gao Q, Zhang W, Pfeilschifter J, Goldstein DS, Geller AI. 2004. Coexpression of tyrosine hydroxylase, GTP cyclohydrolase I, aromatic amino acid decarboxylase, and vesicular monoamine transporter-2 from a helper virus-free HSV-1 vector supports high-level, long-term biochemical and behavioral correction of a rat model of Parkinson's disease. Hum Gene Ther 15:1177-1196. (Pubitemid 40052431)
    • (2004) Human Gene Therapy , vol.15 , Issue.12 , pp. 1177-1196
    • Sun, M.1    Kong, L.2    Wang, X.3    Holmes, C.4    Gao, Q.5    Zhang, G.-R.6    Pfeilschifter, J.7    Goldstein, D.S.8    Geller, A.I.9
  • 60
    • 23644437308 scopus 로고    scopus 로고
    • Comparison of the capability of GDNF, BDNF, or both, to protect nigrostriatal neurons in a rat model of Parkinson's disease
    • DOI 10.1016/j.brainres.2005.05.072, PII S0006899305007912
    • Sun M, Kong L, Wang X, Lu X, Gao Q, Geller AI. 2005. Comparison of protection of nigrostriatal neurons by expression of GDNF, BDNF, or both neurotrophic factors. Brain Res 1052:119-129. (Pubitemid 41116769)
    • (2005) Brain Research , vol.1052 , Issue.2 , pp. 119-129
    • Sun, M.1    Kong, L.2    Wang, X.3    Lu, X.-G.4    Gao, Q.5    Geller, A.I.6
  • 61
    • 0028216874 scopus 로고
    • The protein kinase C family for neuronal signaling
    • Tanaka C, Nishizuka Y. 1994. The protein kinase C family for neuronal signaling. Ann Rev Neurosci 17:551-567. (Pubitemid 24117042)
    • (1994) Annual Review of Neuroscience , vol.17 , pp. 551-567
    • Tanaka, C.1    Nishizuka, Y.2
  • 63
    • 0030002982 scopus 로고    scopus 로고
    • Gene therapy in the adult primate brain. Intraparenchymal grafts of cells genetically modified to produce nerve growth factor prevent cholinergic neuronal degeneration
    • Tuszynski MH, Roberts J, Senut MC, U HS, Gage FH. 1996. Gene therapy in the adult primate brain: Intraparenchymal grafts of cells genetically modified to produce nerve growth factor prevent cholinergic neuronal degeneration. Gene Ther 3:305-314. (Pubitemid 26144640)
    • (1996) Gene Therapy , vol.3 , Issue.4 , pp. 305-314
    • Tuszynski, M.H.1    Roberts, J.2    Senut, M.-C.3    U, H.S.4    Gage, F.H.5
  • 65
    • 0034959451 scopus 로고    scopus 로고
    • General strategy for constructing large HSV-1 plasmid vectors that co-express multiple genes
    • Wang X, Zhang G, Sun M, Geller AI. 2001. General strategy for constructing large HSV-1 plasmid vectors that co-express multiple genes. BioTechniques 31:204-212. (Pubitemid 32645926)
    • (2001) BioTechniques , vol.31 , Issue.1 , pp. 204-212
    • Wang, X.1    Zhang, G.R.2    Sun, M.3    Geller, A.I.4
  • 66
    • 0034329818 scopus 로고    scopus 로고
    • Phorbol esters potentiate evoked and spontaneous release by different presynaptic mechanisms
    • Waters J, Smith SJ. 2000. Phorbol esters potentiate evoked and spontaneous release by different presynaptic mechanisms. J Neurosci 20:7863-7870.
    • (2000) J Neurosci , vol.20 , pp. 7863-7870
    • Waters, J.1    Smith, S.J.2
  • 68
    • 0036859751 scopus 로고    scopus 로고
    • Age-related declines in prospective memory: Behavioral and electrophysiological evidence
    • DOI 10.1016/S0149-7634(02)00069-6, PII S0149763402000696
    • West R, Jakubek K, Wymbs N. 2002. Age-related declines in prospective memory: Behavioral and electrophysiological evidence. Neurosci Biobehav Rev 26:827-833. (Pubitemid 35430287)
    • (2002) Neuroscience and Biobehavioral Reviews , vol.26 , Issue.7 , pp. 827-833
    • West, R.1    Jakubek, K.2    Wymbs, N.3
  • 69
    • 0036549053 scopus 로고    scopus 로고
    • Age-related biophysical alterations of hippocampal pyramidal neurons: Implications for learning and memory
    • DOI 10.1016/S1568-1637(01)00009-5, PII S1568163701000095
    • Wu WW, Oh MM, Disterhoft JF. 2002. Age-related biophysical alterations of hippocampal pyramidal neurons: Implications for learning and memory. Ageing Res Rev 1:181-207. (Pubitemid 38340341)
    • (2002) Ageing Research Reviews , vol.1 , Issue.2 , pp. 181-207
    • Wu, W.W.1    Oh, M.M.2    Disterhoft, J.F.3
  • 70
    • 1342290210 scopus 로고    scopus 로고
    • The effects of rAAV2-mediated NGF gene delivery in adult and aged rats
    • DOI 10.1016/j.ymthe.2003.11.010
    • Wu K, Meyers CA, Guerra NK, King MA, Meyer EM. 2004. The effects of rAAV2-mediated NGF gene delivery in adult and aged rats. Mol Ther 9:262-269. (Pubitemid 38256552)
    • (2004) Molecular Therapy , vol.9 , Issue.2 , pp. 262-269
    • Wu, K.1    Meyers, C.A.2    Guerra, N.K.3    King, M.A.4    Meyer, E.M.5
  • 71
    • 27744516865 scopus 로고    scopus 로고
    • AAV2/5-mediated NGF gene delivery protects septal cholinergic neurons following axotomy
    • DOI 10.1016/j.brainres.2005.08.056, PII S0006899305012795
    • Wu K, Meyer EM, Bennett JA, Meyers CA, Hughes JA, King MA. 2005. AAV2/5-mediated NGF gene delivery protects septal cholinergic neurons following axotomy. Brain Res 1061: 107-113. (Pubitemid 41587918)
    • (2005) Brain Research , vol.1061 , Issue.2 , pp. 107-113
    • Wu, K.1    Meyer, E.M.2    Bennett, J.A.3    Meyers, C.A.4    Hughes, J.A.5    King, M.A.6
  • 72
    • 0034624216 scopus 로고    scopus 로고
    • A tyrosine hydroxylase-neurofilament chimeric promoter enhances long-term expression in rat forebrain neurons from helper virus-free HSV-1 vectors
    • Zhang G, Wang X, Yang T, Sun M, Zhang W, Wang Y, Geller AI. 2000. A tyrosine hydroxylase-neurofilament chimeric promoter enhances long-term expression in rat forebrain neurons from helper virus-free HSV-1 vectors. Molec Brain Res 84:17-31.
    • (2000) Molec Brain Res , vol.84 , pp. 17-31
    • Zhang, G.1    Wang, X.2    Yang, T.3    Sun, M.4    Zhang, W.5    Wang, Y.6    Geller, A.I.7
  • 73
    • 2342558135 scopus 로고    scopus 로고
    • Comparison of the immune response to gene transfer into the rat brain with helper or helper virus-free HSV-1 vectors [in Chinese]
    • Zhang W, Geller A. 2002. Comparison of the immune response to gene transfer into the rat brain with helper or helper virus-free HSV-1 vectors [in Chinese]. Hua Xi Yi Ke Da Xue Xue Bao 33:175-178.
    • (2002) Hua Xi Yi Ke Da Xue Xue Bao , vol.33 , pp. 175-178
    • Zhang, W.1    Geller, A.2
  • 74
    • 24944578263 scopus 로고    scopus 로고
    • Genetic enhancement of visual learning by activation of protein kinase C pathways in small groups of rat cortical neurons
    • DOI 10.1523/JNEUROSCI.2271-05.2005
    • Zhang G, Wang X, Kong L, Lu X, Lee B, Liu M, Sun M, Franklin C, Cook RG, Geller AI. 2005. Genetic enhancement of visual learning by activation of protein kinase C pathways in small groups of rat cortical neurons. J Neurosci 25:8468-8481. (Pubitemid 41324733)
    • (2005) Journal of Neuroscience , vol.25 , Issue.37 , pp. 8468-8481
    • Zhang, G.-R.1    Wang, X.2    Kong, L.3    Lu, X.-G.4    Lee, B.5    Liu, M.6    Sun, M.7    Franklin, C.8    Cook, R.G.9    Geller, A.I.10
  • 75
    • 0036978779 scopus 로고    scopus 로고
    • Improvement of spatial learning and memory after adenovirus-mediated transfer of the nerve growth factor gene to aged rat brain
    • DOI 10.1089/104303402320987860
    • Zou L, Yuan X, Long Y, Shine HD, Yang K. 2002. Improvement of spatial learning and memory after adenovirus-mediated transfer of the nerve growth factor gene to aged rat brain. Hum Gene Ther 13:2173-2184. (Pubitemid 36418811)
    • (2002) Human Gene Therapy , vol.13 , Issue.18 , pp. 2173-2184
    • Zou, L.1    Yuan, X.2    Long, Y.3    Shine, H.D.4    Yang, K.5
  • 76
    • 0036978779 scopus 로고    scopus 로고
    • Improvement of spatial learning and memory after adenovirus-mediated transfer of the nerve growth factor gene to aged rat brain
    • DOI 10.1089/104303402320987860
    • Zou L, Yuan X, Long Y, Shine HD, Yang K. 2002. Improvement of spatial learning and memory after adenovirus-mediated transfer of the nerve growth factor gene to aged rat brain. Hum Gene Ther 13:2173-2184. (Pubitemid 36418811)
    • (2002) Human Gene Therapy , vol.13 , Issue.18 , pp. 2173-2184
    • Zou, L.1    Yuan, X.2    Long, Y.3    Shine, H.D.4    Yang, K.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.