Na+/H+ exchanger mediates TNF-α-induced hepatocyte apoptosis via the calpain-dependent degradation of Bcl-xL

Journal of Gastroenterology and Hepatology (Australia)

Volumn 24, Issue 5, 2009, Pages 879-885

  Liu, Zhan ^a,b   Wang, Shuangxi ^c   Zhou, Huixin ^b   Yang, Yuming ^b   Zhang, Mingliang ^d  

^a People's Hospital of Hunan Province   (China)

^b HUNAN NORMAL UNIVERSITY   (China)

^c UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

^d Hospital of Nanhua University   (China)

Author keywords

Apoptosis; Bcl xL; Calpain; Hepatocyte; Tumor necrosis factor

Indexed keywords

BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; CALPAIN; CARIPORIDE; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; MESSENGER RNA; PROTEIN BAK; PROTEIN BAX; PROTEIN BCL XL; SODIUM PROTON EXCHANGE PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CELL CULTURE; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; HUMAN; HUMAN CELL; LIVER CELL; LIVER DISEASE; PRIORITY JOURNAL; PROTEIN DEGRADATION;

APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BCL-X PROTEIN; CALCIUM; CALPAIN; CELLS, CULTURED; CHELATING AGENTS; CYSTEINE PROTEINASE INHIBITORS; DIPEPTIDES; DOSE-RESPONSE RELATIONSHIP, DRUG; EGTAZIC ACID; GUANIDINES; HEPATOCYTES; HUMANS; SIGNAL TRANSDUCTION; SODIUM-HYDROGEN ANTIPORTER; SULFONES; TIME FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 65949123582     PISSN: 08159319     EISSN: 14401746     Source Type: Journal    
DOI: 10.1111/j.1440-1746.2008.05715.x     Document Type: Article

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