Preferential glutathione conjugation of a reverse diol epoxide compared to a bay region diol epoxide of phenanthrene in human hepatocytes: Relevance to molecular epidemiology studies of glutathione-s-transferase polymorphisms and cancer

Chemical Research in Toxicology

Volumn 22, Issue 3, 2009, Pages 426-432

  Hecht, Stephen S ^a   Berg, Jeannette Zinggeler ^a   Hochalter, J Bradley ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; ACETYLCYSTEINE DERIVATIVE; ANTIPHENANTHRENE 1,2 DIOL 3,4 EPOXIDE; ANTIPHENANTHRENE 3,4 DIOL 1,2 EPOXIDE; EPOXIDE; GLUTATHIONE; GLUTATHIONE TRANSFERASE; PHENANTHRENE DERIVATIVE; PHENANTHRENEQUINONE; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; BAY REGION BINDING SITE; CONJUGATION; CONTROLLED STUDY; FEMALE; GENETIC POLYMORPHISM; HUMAN; HUMAN CELL; INCUBATION TIME; LIVER CELL; MALE; MOLECULAR EPIDEMIOLOGY;

ACETYLCYSTEINE; ADULT; AGED; AGED, 80 AND OVER; BAY-REGION, POLYCYCLIC AROMATIC HYDROCARBON; FEMALE; GLUTATHIONE; GLUTATHIONE TRANSFERASE; HEPATOCYTES; HUMANS; MALE; METABOLIC DETOXICATION, PHASE II; MIDDLE AGED; NEOPLASMS; PHENANTHRENES; POLYMORPHISM, GENETIC;

EID: 65949121359     PISSN: 0893228X     EISSN: 15205010     Source Type: Journal    
DOI: 10.1021/tx800315m     Document Type: Article

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