Correlation between molecular and histopathological diagnoses of B cell lymphomas in bone marrow biopsy and aspirates

Journal of Clinical Pathology

Volumn 62, Issue 4, 2009, Pages 357-360

  Ilgenfritz, R B ^a   Kayasut, K ^a   Tourneau, A Le ^a   Calendini, O A ^a   Ouafi, L ^a   Marzac, C ^a   Diebold, J ^a   Devez, F ^a   Ducruit, V ^a   Bouchet, P E ^a   Audouin, J ^a   Molina, T J ^a  

^a HÔTEL DIEU   (France)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN HEAVY CHAIN; MOLECULAR MARKER; PROTEIN BCL 2;

ARTICLE; B CELL LYMPHOMA; BONE MARROW BIOPSY; CANCER DIAGNOSIS; CANCER LOCALIZATION; CELL STRUCTURE; CHRONIC LYMPHATIC LEUKEMIA; COMPARATIVE STUDY; CONTROLLED STUDY; FOLLICULAR LYMPHOMA; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MANTLE CELL LYMPHOMA; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RETROSPECTIVE STUDY;

BIOPSY; BONE MARROW; BONE MARROW EXAMINATION; GENES, BCL-2; HUMANS; IMMUNOGLOBULIN HEAVY CHAINS; LYMPHOMA, B-CELL; POLYMERASE CHAIN REACTION; REPRODUCIBILITY OF RESULTS; RETROSPECTIVE STUDIES;

EID: 65849289339     PISSN: 00219746     EISSN: 14724146     Source Type: Journal    
DOI: 10.1136/jcp.2008.061622     Document Type: Article

References (28)

1. Thiele J, Zirbes TK, Kvasicka HM, et al. Focal lymphoid aggregates (nodules) in bone marrow biopsies: differentiation between benign hyperplasia and malignant lymphoma-a practical guideline. J Clin Pathol 1999;52:294-300. (Pubitemid 29161494)
2. Swerdlow SH, Campo E, Harris NL, et al. World Health Organization Classification of Tumors. Vol 2. Pathology and genetics of tumors of haematopoietic and lymphoid tissues. 4th edn. Lyon: IARC Press; 2008.
3. Lust JA. Molecular genetics and lymphoproliferative disorders. J Clin Lab Anal 1996;10:359-367 (Pubitemid 26398922)
4. Segal GH, Jorgensen T, Scott M, et al. Optimal primer selection for clonality assessment by polymerase chain reaction analysis. Hum Pathol 1994;25:1276-1282
5. Coad JE, Olson DJ, Christensen DR, et al. Correlation of PCR-detected clonal gene rearrangements with bone marrow morphology in patients with B-lineage lymphomas. Am J Surg Pathol 1997;21:1047-1056 (Pubitemid 27407289)
6. Lossos IS, Okada CY, Tibshirani R, etal. Molecular analysis of immunoglobulin genes in diffuse large B-cell lymphomas. Blood 2000;95:1797-1803 (Pubitemid 30120845)
7. Krober SM, Horny HP, Greschniok A, et al. Reactive and neoplastic lymphocytes in human bone marrow: morphological, immunohistological, and molecular biological investigations on biopsy specimens. J Clin Pathol 1999;52:521-526 (Pubitemid 29309211)
8. Maes B, Achten R, Demunter A, et al. Evaluation of B cell lymphoid infiltrates in bone marrow biopsies by morphology, immunohistochemistry, and molecular analysis. J Clin Pathol 2000;53:835-840
9. Diss TC, Liu HX, Du MQ, et al. Improvement to B cell clonality analysis using PCR amplification of immunoglobulin l IGHt chain genes. J Clin Pathol 2002;55:98-101. (Pubitemid 34293411)
10. Kang YH, Park CJ, Seo EJ, et al. Polymerase chain reaction-based diagnosis of bone marrow involvement in 170 cases of non-Hodgkin lymphoma. Cancer 2002;94:3073-3082 (Pubitemid 34670489)
11. Evans PA, Pott Ch, Groenen PJ, et al. Significantly improved PCR-based clonality testing in B-cell malignancies by use of multiple immunoglobulin gene targets. Report of the BIOMED-2 Concerted Action BHM4-CT98-3936. Leukemia 2007;21:207-214 (Pubitemid 46158111)
12. Camilleri-Broet S, Devez F, Tissier F, et al. Quality control and sensitivity of polymerase chain reaction techniques for the assessment of immunoglobulin heavy chain gene rearrangements from fixed- and paraffin-embedded samples. Ann Diagn Pathol 2000;4:71-76
13. Molina TJ, Devez F, Bigorgne C, et al. Detection of Bcl-2 rearrangement in HIV- related follicular lymphoid hyperplasia. Br J Haematol 1996;94:705-8.
14. Braunschweig R, Baur AS, Delacretaz F, et al. Contribution of IGH-PCR to the evaluation of B-cell lymphoma involvement in paraffin-embedded bone marrow biopsy specimens. Am J Clin Pathol 2003;119:634-712
15. Zhou XG, Sandvej K, Gregersen N, et al. Detection of clonal B cells in microdissected reactive lymphoproliferations: possible diagnostic pitfalls in PCR analysis of immunoglobulin heavy chain gene rearrangement. J Clin Pathol 1999;52:104-110 (Pubitemid 29166733)
16. Elenitoba-Johson KSJ, Bohling SD, Mitchell RS, et al. PCR analysis of immunoglobulin heavy chain gene in polyclonal processes can yield pseudoclonal bands as an artifact of low B cell number. J Mol Diag 2000;2:92-96
17. Aarts WM, Bende RJ, Steenbergen EJ, et al. Variable heavy chain gene analysis of follicular lymphomas: correlation between heavy chain isotype expression and somatic mutation load. Blood 2000;95:2922-2929 (Pubitemid 30235904)
18. Aarts WM, Bende RJ, Bossenbroek JG, et al. Variable heavy-chain gene analysis of follicular lymphomas: subclone selection rather than clonal evolution over time. Blood 2001;98:238-240
19. Ottensmeier CH, Thompsett AR, Zhu D, et al. Analysis of VRHR genes in follicular and diffuse lymphoma shows ongoing somatic mutation and multiple isotype transcripts in early disease with changes during disease progression. Blood 1998;91:4292-4299 (Pubitemid 28261994)
20. Matolcsy A, Schattner EJ, Knowles DM, et al. Clonal evolution of B cells in transformation from low- to high-grade lymphoma. Eur J Immunol 1999;29:1253-1264 (Pubitemid 29164172)
21. Rambaldi A, Lazzari M, Manzoni C, et al. Monitoring of minimal residual disease after CHOP and rituximab in previously untreated patients with follicular lymphoma. Blood 2002;99:856-862 (Pubitemid 34525546)
22. Lopez-Guillermo A, Cabanillas F, McLaughlin P, et al. The clinical significance of molecular response in indolent follicular lymphomas. Blood 1998;91:2955-2960 (Pubitemid 28227546)
23. Corradini P, Astolfi M, Cherasco C, et al. Molecular monitoring of minimal residual disease in follicular and mantle cell non-Hodgkin's lymphomas treated with high-dose chemotherapy and peripheral blood progenitor cell autografting. Blood 1997;89:724-731 (Pubitemid 27051709)
24. Freedman AS, Neuberg D, Mauch P, et al. Long-term follow-up of autologous bone marrowtransplantation in patients with relapsed follicular lymphoma. Blood 1999;94:3325. (Pubitemid 29536125)
25. Rambaldi A, Carlotti E, Oldani E, Della Starza I, Baccarani M, et al. Quantitative PCR of bone marrow BCL2/IGH+ cells at diagnosis predicts treatment response and long-term outcome in follicular non-Hodgkin lymphoma. Blood 2005;105:3428-3433 (Pubitemid 40628182)
26. Ladetto M, Drandi D, Compagno M, et al. PCR-detectable nonneoplastic Bcl-2/IGH rearrangements are common in normal subjects and cancer patients at diagnosis but rare in subjects treated with chemotherapy. J Clin Oncol 2003;21:1398-1403 (Pubitemid 46606422)
27. Limpens J, Stad R, Vos C, et al. Lymphoma-associated translocation t(14;18) in blood B cells of normal individuals. Blood 1995;85:2528-2536
28. Summers KE, Goff LK, Wilson AG, et al. Frequency of the Bcl-2/IGH rearrangement in normal individuals: implications for the monitoring of disease in patients with follicular lymphoma. J Clin Oncol 2001;19:420-424 (Pubitemid 32112854)