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Volumn 1, Issue 4, 2007, Pages 465-472

Inhalation of activated protein C: A possible new adjunctive intervention in acute respiratory distress syndrome

Author keywords

Activated protein c inhalation; Ards; Pulmonary hemostasis; Pulmonary host defense

Indexed keywords


EID: 65849197141     PISSN: 11775475     EISSN: 11775491     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (10)

References (39)
  • 1
    • 0037394676 scopus 로고    scopus 로고
    • Neutrophils and acute lung injury
    • Abraham E. 2003. Neutrophils and acute lung injury. Crit Care Med, 31: S195-S199.
    • (2003) Crit Care Med , vol.31
    • Abraham, E.1
  • 3
    • 34447294235 scopus 로고    scopus 로고
    • The alveolar epithelium can initiate the extrinsic coagulation cascade through expression of tissue factor
    • Bastarache JA, Wang L, Geiser T, et al. 2007. The alveolar epithelium can initiate the extrinsic coagulation cascade through expression of tissue factor. Thorax, 62:608-16.
    • (2007) Thorax , vol.62 , pp. 608-616
    • Bastarache, J.A.1    Wang, L.2    Geiser, T.3
  • 4
    • 0035164538 scopus 로고    scopus 로고
    • Safety and dose relationship of recombinant human activated protein C for coagulopathy in severe sepsis
    • Bernard GR, Ely EW, Wright TJ, et al. 2001a. Safety and dose relationship of recombinant human activated protein C for coagulopathy in severe sepsis. Crit Care Med, 29:2051-9.
    • (2001) Crit Care Med , vol.29 , pp. 2051-2059
    • Bernard, G.R.1    Ely, E.W.2    Wright, T.J.3
  • 5
    • 0035826096 scopus 로고    scopus 로고
    • Recombinant human protein C Worldwide Evaluation in Severe Sepsis (PROWESS) study group. Efficacy and safety of recombinant human activated protein C for severe sepsis
    • Bernard GR, Vincent JL, Laterre PF, et al. 2001b. Recombinant human protein C Worldwide Evaluation in Severe Sepsis (PROWESS) study group. Efficacy and safety of recombinant human activated protein C for severe sepsis. N Engl J Med, 344:699-709.
    • (2001) N Engl J Med , vol.344 , pp. 699-709
    • Bernard, G.R.1    Vincent, J.L.2    Laterre, P.F.3
  • 6
    • 34247388903 scopus 로고    scopus 로고
    • Recombinant human activated protein C inhibits local and systemic activation of coagulation without influencing inflammation during Pseudomonas aeruginosa pneumonia in rats
    • Choi G, Hofstra JJ, Roelofs JJ, et al. 2007. Recombinant human activated protein C inhibits local and systemic activation of coagulation without influencing inflammation during Pseudomonas aeruginosa pneumonia in rats. Crit Care Med, 35:1362-8.
    • (2007) Crit Care Med , vol.35 , pp. 1362-1368
    • Choi, G.1    Hofstra, J.J.2    Roelofs, J.J.3
  • 7
    • 21544447526 scopus 로고    scopus 로고
    • Regulation of blood coagulation by the protein C anticoagulant pathway: Novel insights into structure-function relationships and molecular recognition
    • Dahlback B, Villoutreix BO. 2005. Regulation of blood coagulation by the protein C anticoagulant pathway: novel insights into structure-function relationships and molecular recognition. Arterioscler Thromb Vasc Biol, 25:1311-20.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 1311-1320
    • Dahlback, B.1    Villoutreix, B.O.2
  • 8
    • 34247632571 scopus 로고    scopus 로고
    • The apoptotic pathway as a therapeutic target in sepsis
    • Doreen E. Wesche-Soldato, Ryan Z, et al. 2007. The apoptotic pathway as a therapeutic target in sepsis. Curr Drug Targets, 8(4):493-500.
    • (2007) Curr Drug Targets , vol.8 , Issue.4 , pp. 493-500
    • Doreen, E.1    Ryan, Z.2
  • 9
    • 22044454812 scopus 로고    scopus 로고
    • Aerosol deposition in neonatal ventilation
    • Dubus JC, Vecellio L, De Monte M, et al. 2005. Aerosol deposition in neonatal ventilation. Pediatr Res, 58:10-14.
    • (2005) Pediatr Res , vol.58 , pp. 10-14
    • Dubus, J.C.1    Vecellio, L.2    de Monte, M.3
  • 10
    • 33646480218 scopus 로고    scopus 로고
    • Inflammation and the activated protein C anticoagulant pathway
    • Suppl
    • Esmon CT. 2006. Inflammation and the activated protein C anticoagulant pathway. Semin Thromb Hemost, Suppl 1:49-60.
    • (2006) Semin Thromb Hemost , vol.1 , pp. 49-60
    • Esmon, C.T.1
  • 11
    • 30744439278 scopus 로고    scopus 로고
    • Endothelial protein C receptor-dependent inhibition of migration of human lymphocytes by protein C involves epidermal growth factor receptor
    • Feistritzer C, Mosheimer BA, Sturn DH, et al. 2006. Endothelial protein C receptor-dependent inhibition of migration of human lymphocytes by protein C involves epidermal growth factor receptor. J Immunol, 176:1019-25.
    • (2006) J Immunol , vol.176 , pp. 1019-1025
    • Feistritzer, C.1    Mosheimer, B.A.2    Sturn, D.H.3
  • 12
    • 0038467214 scopus 로고    scopus 로고
    • Thrombin-activatable fibrinolysis inhibitor and protein C inhibitor in interstitial lung disease
    • Fujimoto H, Gabazza EC, Hataji O, et al. 2003. Thrombin-activatable fibrinolysis inhibitor and protein C inhibitor in interstitial lung disease. Am J Respir Crit Care Med, 167:1687-94.
    • (2003) Am J Respir Crit Care Med , vol.167 , pp. 1687-1694
    • Fujimoto, H.1    Gabazza, E.C.2    Hataji, O.3
  • 13
    • 33947394457 scopus 로고    scopus 로고
    • Mechanical ventilation in ARDS: A state-of-the-art review
    • Girard TD, Bernard GR. 2007. Mechanical ventilation in ARDS: a state-of-the-art review Chest, 131:921-9.
    • (2007) Chest , vol.131 , pp. 921-929
    • Girard, T.D.1    Bernard, G.R.2
  • 15
    • 34247268318 scopus 로고    scopus 로고
    • Reduced toll-like receptor 4 and substance P gene expression is associated with airway bacterial colonization in children
    • Grissell TV, Chang AB, Gibson PG. 2007. Reduced toll-like receptor 4 and substance P gene expression is associated with airway bacterial colonization in children. Pediatr Pulmonol, 42:380-5.
    • (2007) Pediatr Pulmonol , vol.42 , pp. 380-385
    • Grissell, T.V.1    Chang, A.B.2    Gibson, P.G.3
  • 16
    • 0343158249 scopus 로고    scopus 로고
    • Alveolar fibrin formation caused by enhanced procoagulant and depressed fibrinolytic capacities in severe pneumonia: Comparison with the acute respiratory distress syndrome
    • Günther A, Mosavi P, Heinemann S, et al. 2000. Alveolar fibrin formation caused by enhanced procoagulant and depressed fibrinolytic capacities in severe pneumonia: comparison with the acute respiratory distress syndrome. Am J Respir Crit Care Med, 161:454-62.
    • (2000) Am J Respir Crit Care Med , vol.161 , pp. 454-462
    • Günther, A.1    Mosavi, P.2    Heinemann, S.3
  • 17
    • 0029626658 scopus 로고
    • Binding of activated protein C to a specific receptor on human mononuclear phagocytes inhibits intracellular calcium signaling and monocyte-dependent proliferative responses
    • Hancock WW, Grey ST, Hau L, et al. 1995. Binding of activated protein C to a specific receptor on human mononuclear phagocytes inhibits intracellular calcium signaling and monocyte-dependent proliferative responses. Transplantation, 60:1525-32.
    • (1995) Transplantation , vol.60 , pp. 1525-1532
    • Hancock, W.W.1    Grey, S.T.2    Hau, L.3
  • 18
    • 0021972727 scopus 로고
    • Pulmonary complications of bone marrow transplantation
    • Krowka MJ, Rosenow EC 3rd, Hoagland HC. 1985. Pulmonary complications of bone marrow transplantation. Chest, 87:237-46.
    • (1985) Chest , vol.87 , pp. 237-246
    • Krowka, M.J.1    Rosenow, E.C.2    Hoagland, H.C.3
  • 19
    • 33845914938 scopus 로고    scopus 로고
    • Salmeterol enhances pulmonary fibrinolysis in healthy volunteers
    • Maris NA, Vos AF, Bresser P, et al. 2007. Salmeterol enhances pulmonary fibrinolysis in healthy volunteers. Crit Care Med, 35:57-63.
    • (2007) Crit Care Med , vol.35 , pp. 57-63
    • Maris, N.A.1    Vos, A.F.2    Bresser, P.3
  • 20
    • 34147119744 scopus 로고    scopus 로고
    • The cytoprotective protein C pathway
    • Mosnier LO, Zlokovic BV, Griffin JH. 2007. The cytoprotective protein C pathway. Blood, 109:3161-72.
    • (2007) Blood , vol.109 , pp. 3161-3172
    • Mosnier, L.O.1    Zlokovic, B.V.2    Griffin, J.H.3
  • 21
    • 10244229104 scopus 로고    scopus 로고
    • Recombinant human activated protein C reduces human endotoxin-induced pulmonary inflammation via inhibition of neutrophil chemotaxis
    • Nick JA, Coldren CD, Geraci MW, et al. 2004. Recombinant human activated protein C reduces human endotoxin-induced pulmonary inflammation via inhibition of neutrophil chemotaxis. Blood, 104:3878-85.
    • (2004) Blood , vol.104 , pp. 3878-3885
    • Nick, J.A.1    Coldren, C.D.2    Geraci, M.W.3
  • 22
    • 11144241287 scopus 로고    scopus 로고
    • Aerosols of compacted DNA nanoparticles retain structural integrity and biological activity
    • Oette SM, Gedeon CR, Kowalczyk TH, et al. 2004. Aerosols of compacted DNA nanoparticles retain structural integrity and biological activity. Mol Ther, 9:S190.
    • (2004) Mol Ther , vol.9
    • Oette, S.M.1    Gedeon, C.R.2    Kowalczyk, T.H.3
  • 23
    • 0037318946 scopus 로고    scopus 로고
    • Bench-to-bedside review: Functional relationships between coagulation and the innate immune response and their respective roles in the pathogenesis of sepsis
    • Opal SM, and Esmon CT. 2003. Bench-to-bedside review: functional relationships between coagulation and the innate immune response and their respective roles in the pathogenesis of sepsis. Crit Care, 7(1):23-38.
    • (2003) Crit Care , vol.7 , Issue.1 , pp. 23-38
    • Opal, S.M.1    Esmon, C.T.2
  • 24
    • 33644845172 scopus 로고    scopus 로고
    • Outcome of critically ill allogeneic hematopoietic stem-cell transplantation recipients: A reappraisal of indications for organ failure supports
    • Pène F, Aubron C, Azoulay E et al. 2006. Outcome of critically ill allogeneic hematopoietic stem-cell transplantation recipients: a reappraisal of indications for organ failure supports. J Clin Oncol, 24:643-9.
    • (2006) J Clin Oncol , vol.24 , pp. 643-649
    • Pène, F.1    Aubron, C.2    Azoulay, E.3
  • 25
    • 0033037431 scopus 로고    scopus 로고
    • Secretory leukocyte proteinase inhibitor is preferentially increased in patients with acute respiratory distress syndrome
    • Sallenave JM, Donnelly SC, Grant IS. 1999. Secretory leukocyte proteinase inhibitor is preferentially increased in patients with acute respiratory distress syndrome. Eur Respir J, 13:1029-36.
    • (1999) Eur Respir J , vol.13 , pp. 1029-1036
    • Sallenave, J.M.1    Donnelly, S.C.2    Grant, I.S.3
  • 26
    • 33644598461 scopus 로고    scopus 로고
    • Pulmonary coagulopathy as a new target in therapeutic studies of acute lung injury or pneumonia a review
    • Schultz MJ, Haitsma JJ, Zhang H, et al. 2006. Pulmonary coagulopathy as a new target in therapeutic studies of acute lung injury or pneumonia a review. Crit Care Med, 34:871-7.
    • (2006) Crit Care Med , vol.34 , pp. 871-877
    • Schultz, M.J.1    Haitsma, J.J.2    Zhang, H.3
  • 27
    • 33749342903 scopus 로고    scopus 로고
    • Urokinase induces activation of STAT3 in lung epithelial cells
    • Shetty S, Rao GN, Cines DB, et al. 2006. Urokinase induces activation of STAT3 in lung epithelial cells. Am J Physiol Lung Cell Mol Physiol, 291:772-80.
    • (2006) Am J Physiol Lung Cell Mol Physiol , vol.291 , pp. 772-780
    • Shetty, S.1    Rao, G.N.2    Cines, D.B.3
  • 28
    • 0032717834 scopus 로고    scopus 로고
    • Mechanical ventilation in hematopoietic stem cell transplantation: Can we effectively predict outcomes?
    • Shorr AF, Moores LK, Edenfield WJ, et al. 1999. Mechanical ventilation in hematopoietic stem cell transplantation: can we effectively predict outcomes? Chest, 116:1012-18.
    • (1999) Chest , vol.116 , pp. 1012-1018
    • Shorr, A.F.1    Moores, L.K.2    Edenfield, W.J.3
  • 29
    • 33750979835 scopus 로고    scopus 로고
    • Inhalation of activated protein C inhibits endotoxin-induced pulmonary inflammation in mice indepen-dent of neutrophil recruitment
    • Slofstra SH, Groot AP, Maris NA, et al. 2006. Inhalation of activated protein C inhibits endotoxin-induced pulmonary inflammation in mice indepen-dent of neutrophil recruitment. Br J Pharmacol, 149:740-6.
    • (2006) Br J Pharmacol , vol.149 , pp. 740-746
    • Slofstra, S.H.1    Groot, A.P.2    Maris, N.A.3
  • 30
    • 33746888276 scopus 로고    scopus 로고
    • Modulation of monocyte function by activated protein C, a natural anticoagulant
    • Stephenson DA, Toltl LJ, Beaudin S, et al. 2006. Modulation of monocyte function by activated protein C, a natural anticoagulant. J Immunol, 177:2115-22.
    • (2006) J Immunol , vol.177 , pp. 2115-2122
    • Stephenson, D.A.1    Toltl, L.J.2    Beaudin, S.3
  • 31
    • 0043240071 scopus 로고    scopus 로고
    • Expression and function of the endothelial protein C receptor in human neutrophils
    • Sturn DH, Kaneider NC, Feistritzer C, et al. 2003. Expression and function of the endothelial protein C receptor in human neutrophils. Blood, 102:1499-505.
    • (2003) Blood , vol.102 , pp. 1499-1505
    • Sturn, D.H.1    Kaneider, N.C.2    Feistritzer, C.3
  • 32
    • 33645855220 scopus 로고    scopus 로고
    • Lung Inflammation in ARDS-Friend or Foe? Editorial
    • Suter PM. 2006. Lung Inflammation in ARDS-Friend or Foe? Editorial. N Engl J Med, 354:1739-41.
    • (2006) N Engl J Med , vol.354 , pp. 1739-1741
    • Suter, P.M.1
  • 33
    • 33645865234 scopus 로고    scopus 로고
    • Efficacy and safety of corticosteroids for persistent acute respiratory distress syndrome
    • The National Heart, Lung, and Blood Institute Acute Respiratory Distress Syndrome (ARDS) Clinical Trials Network
    • The National Heart, Lung, and Blood Institute Acute Respiratory Distress Syndrome (ARDS) Clinical Trials Network. 2006. Efficacy and safety of corticosteroids for persistent acute respiratory distress syndrome. N Engl J Med, 354:1671-84.
    • (2006) N Engl J Med , vol.354 , pp. 1671-1684
  • 34
    • 18644373364 scopus 로고    scopus 로고
    • Activated protein C inhibits local coagulation after intrapulmonary delivery of endotoxin in humans
    • van der Poll T, Levi M, Nick JA, et al. 2005.Activated protein C inhibits local coagulation after intrapulmonary delivery of endotoxin in humans. Am J Respir Crit Care Med, 171:1125-8.
    • (2005) Am J Respir Crit Care Med , vol.171 , pp. 1125-1128
    • van der Poll, T.1    Levi, M.2    Nick, J.A.3
  • 35
    • 34247216695 scopus 로고    scopus 로고
    • Novel role of the human alveolar epithelium in regulating intra-alveolar coagulation
    • Wang L, Bastarache JA, Wickersham N, et al. 2007. Novel role of the human alveolar epithelium in regulating intra-alveolar coagulation. Am J Respir Cell Mol Biol, 36:497-503.
    • (2007) Am J Respir Cell Mol Biol , vol.36 , pp. 497-503
    • Wang, L.1    Bastarache, J.A.2    Wickersham, N.3
  • 37
    • 27644463452 scopus 로고    scopus 로고
    • Graft versus host-associated pulmonary disease and other idiopathic pulmonary complications after hematopoietic stem cell transplant
    • Watkins TR, Chien JW, Crawford SW. 2005. Graft versus host-associated pulmonary disease and other idiopathic pulmonary complications after hematopoietic stem cell transplant. Semin Respir Crit Care Med, 26:482-89.
    • (2005) Semin Respir Crit Care Med , vol.26 , pp. 482-489
    • Watkins, T.R.1    Chien, J.W.2    Crawford, S.W.3
  • 38
    • 34247588117 scopus 로고    scopus 로고
    • Acute lung injury and the acute respiratory distress syndrome: A clinical review
    • Wheeler AP, Bernard GR. 2007. Acute lung injury and the acute respiratory distress syndrome: a clinical review. Lancet, 369(9572):1553-64.
    • (2007) Lancet , vol.369 , Issue.9572 , pp. 1553-1564
    • Wheeler, A.P.1    Bernard, G.R.2
  • 39
    • 12144291151 scopus 로고    scopus 로고
    • Activated protein C inhibits bronchial hyperresponsiveness and Th2 cytokine expression in mice
    • Yuda H, Adachi Y, Taguchi O, et al. 2004. Activated protein C inhibits bronchial hyperresponsiveness and Th2 cytokine expression in mice. Blood, 103:2196-204.
    • (2004) Blood , vol.103 , pp. 2196-2204
    • Yuda, H.1    Adachi, Y.2    Taguchi, O.3


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