High-throughput micro-computed tomography imaging as a method to evaluate rat and rabbit fetal skeletal abnormalities for developmental toxicity studies

Journal of Pharmacological and Toxicological Methods

Volumn 59, Issue 3, 2009, Pages 156-165

  Winkelmann, Christopher T ^a   Wise, L David ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Alizarin red staining; Fetus; Imaging; Methods; Micro CT; Rabbit; Rat; Skeletal evaluation; Toxicology; X ray computed tomography

Indexed keywords

ALIZARIN RED S;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE DISEASE; CONTROLLED STUDY; DEVELOPMENTAL DISORDER; DIAGNOSTIC ACCURACY; EX VIVO STUDY; FETOTOXICITY; HIGH THROUGHPUT MICRO-COMPUTED TOMOGRAPHY; IMAGE ANALYSIS; IMAGE PROCESSING; IN VIVO STUDY; INTERMETHOD COMPARISON; MICRO-COMPUTED TOMOGRAPHY; NONHUMAN; RABBIT; RAT; STAINING;

ANIMALS; ANTHRAQUINONES; BONE AND BONES; BONE DEVELOPMENT; FEMALE; FETUS; PREGNANCY; RABBITS; RATS; STAINING AND LABELING; TOXICITY TESTS; X-RAY MICROTOMOGRAPHY;

ORYCTOLAGUS CUNICULUS; RATTUS;

EID: 65849192511     PISSN: 10568719     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vascn.2009.03.004     Document Type: Article

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