A peptidyl-prolyl isomerase, FKBP12, accumulates in Alzheimer neurofibrillary tangles

Neuroscience Letters

Volumn 459, Issue 2, 2009, Pages 96-99

  Sugata, Hisato ^a   Matsuo, Kazuhiko ^a   Nakagawa, Taisuke ^a   Takahashi, Mikiko ^a   Mukai, Hideyuki ^a   Ono, Yoshitaka ^a   Maeda, Kiyoshi ^b   Akiyama, Haruhiko ^c   Kawamata, Toshio ^a  

^a KOBE UNIVERSITY   (Japan)

^b Faculty of Science   (Japan)

^c TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

Author keywords

Alzheimer's disease; FKBP12; Intermediate filament; Neurofibrillary tangles; Peptidyl prolyl isomerase; Tau

Indexed keywords

FK BINDING PROTEIN 12; GLIAL FIBRILLARY ACIDIC PROTEIN; PEPTIDYLPROLYL ISOMERASE; TAU PROTEIN; UNCLASSIFIED DRUG;

ADULT; AGED; ALZHEIMER DISEASE; ARTICLE; AUTOPSY; CELLULAR DISTRIBUTION; CLINICAL ARTICLE; CONTROLLED STUDY; ENTORHINAL CORTEX; ENZYME LOCALIZATION; FEMALE; HIPPOCAMPUS; HUMAN; HUMAN TISSUE; MALE; NEUROFIBRILLARY TANGLE; NEUROPIL THREAD; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; SENILE PLAQUE; SUBICULUM;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; ASTROCYTES; AXONS; BRAIN; FEMALE; GLIAL FIBRILLARY ACIDIC PROTEIN; HUMANS; MALE; MIDDLE AGED; NEUROFIBRILLARY TANGLES; NEUROFILAMENT PROTEINS; NEURONS; PHOSPHORYLATION; SENILE PLAQUES; TACROLIMUS BINDING PROTEIN 1A; TAU PROTEINS;

EID: 65749119808     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2009.04.062     Document Type: Article

References (16)

1. Alafuzoff I., Iqbal K., Friden H., Adolfsson R., and Winblad B. Histopathological criteria for progressive dementia disorders: clinicopathologial correlation and classification by multivariate data analysis. Acta Neuropathol. 74 (1987) 209-225
2. Ballatore C., Lee V.M.-Y., and Trojanowski J.Q. Tau-mediated neurodegeneration in Alzheimer's disease and related disorders. Nat. Rev. Neurosci. 8 (2007) 663-672
3. Cong B.K., Hong Y., Sirano D.P., and Ho S.Y. FKBP12 family proteins: immunophilins with versatile biological functions. Neurosignals 16 (2008) 318-325
4. Edlich F., and Fischer G. Pharmacological targeting of catalyzed protein folding: the example of peptide bond cis-trans isomerases. Handb. Exp. Pharmacol. 172 (2006) 359-404
5. Hamdane M., Dourlen P., Bretteville A., Sambo A.V., Ferreira S., Ando K., Kerdraon O., Bégard S., Geay L., Lippens G., Sergeant N., Delacourte A., Maurage C.A., Galas M.C., and Buée L. Pin1 allows for differential tau dephosphorylation in neuronal cells. Mol. Cell Neurosci. 32 (2006) 155-160
6. Hashimoto T., Kawamata T., Saito N., Sasaki M., Nakai M., Niu S., Taniguchi T., Terashima A., Yasuda M., Maeda K., and Tanaka C. Isoform-specific redistribution of calcineurin Aα and Aβ in the hippocampal CA1 region of gerbils after ischemia. J. Neurochem. 70 (1998) 1289-1298
7. Iqbal K., and Grundke-Iqbal I. Ubiquitination and abnormal phosphorylation of paired helical filaments in Alzheimer's disease. Mol. Neurobiol. 5 (1992) 399-410
8. Iqbal K., Alonso Adel C., Chen S., Chohan M.O., El-Akkad E., Cheng-Xin G., Khatoon S., Li B., Liu F., Rahman A., Tanimukai H., and Iqbal I.G.-. Tau pathology in Alzheimer disease and other tauopathies. Biochim. Biophys. Acta 1739 (2005) 198-210
9. Jayaraman T., Brillantes A.M., Timerman A.P., Fleischer S., Erdjument-Bromage H., Tempst P., and Marks A.R. FK506 binding protein associated with the calcium release channel (ryanodine receptor). J. Biol. Chem. 267 (1992) 9474-9477
10. Kawamata T., Tooyama I., Yamada T., Walker D.G., and McGeer P.L. Lactotransferrin immunocytochemistry in Alzheimer and normal human brain. Am. J. Pathol. 142 (1993) 1574-1585
11. Kayyali U.S., Zhang W., Yee A.G., Seidman J.G., and Potter H. Cytoskeletal changes in the brains of mice lacking calcineurin Aα. J. Neurochem. 68 (1997) 1668-1678
12. Kohnken R., Buerger K., Zinkowski R., Miller C., Kerkman D., DeBernardis J., Shen J., Möller H.J., Davies P., and Hampel H. Detection of tau phosphorylated threonine 231 in cerebrospinal fluid of Alzheimer's disease patients. Neurosci. Lett. 287 (2000) 187-190
13. Lu P.J., Wulf G., Zhou X.Z., Davies P., and Lu K.P. The prolyl isomerase Pin1 restores the function of Alzheimer-associated phosphorylated tau protein. Nature 399 (1999) 784-788
14. McGeer P.L., and McGeer E.G. Innate immunity, local inflammation and degenerative disease. Sci. Aging Knowl. Environ. 29 (2002) re 3
15. Mukai H., and Ono Y. A novel protein kinase with leucine zipper-like sequence: its catalytic domain is highly homologous to that of protein kinase C. Biochem. Biophys. Res. Commun. 199 (1994) 897-904
16. Zhou X.Z., Kops O., Werner A., Lu P., Shen M., Stoller G., Küllertz G., Stark M., Fischer G., and Lu K. Pin1-dependent prolyl isomerization regulates dephosphorylation of Cdc25c and tau proteins. Mol. Cell 6 (2000) 873-883