Labeling monocytes for imaging chronic inflammation

Quarterly Journal of Nuclear Medicine and Molecular Imaging

Volumn 53, Issue 1, 2009, Pages 78-88

  Van Hemert, F J ^a   Voermans, C ^a,b   Van Eck Smit, B L F ^a   Bennink, R J ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b SANQUIN RESEARCH   (Netherlands)

Author keywords

Fluorodeoxyglucose F18; Monocytes; Radionuclide imaging; Technetium TC 99m exametazime

Indexed keywords

8 QUINOLINOL INDIUM IN 111; CD14 ANTIGEN; CD16 ANTIGEN; CHEMOKINE; CHEMOKINE RECEPTOR CCR2; CHEMOKINE RECEPTOR CCR5; CXCL14 CHEMOKINE; FLUORODEOXYGLUCOSE F 18; HEXAMETHYLPROPYLENE AMINE OXIME TECHNETIUM TC 99M; L SELECTIN; PROTEOGLYCAN;

ATHEROSCLEROSIS; CELL ACTIVITY; CELL ADHESION; CELL DENSITY; CELL DIFFERENTIATION; CELL FUNCTION; CELL ISOLATION; CELL LABELING; CELL MIGRATION; CHRONIC INFLAMMATION; CYTOTOXICITY; DENDRITIC CELL; DRUG HALF LIFE; ENDOTHELIUM CELL; GENETIC TRANSFORMATION; GLUCOSE METABOLISM; GLUCOSE TRANSPORT; HUMAN; MONOCYTE; MONONUCLEAR PHAGOCYTE; PATHOGENESIS; PHOSPHORYLATION; PROTEIN EXPRESSION; PURIFICATION; REVIEW; RHEUMATOID ARTHRITIS; SCINTISCANNING;

CHRONIC DISEASE; HUMANS; INFLAMMATION; MONOCYTES; STAINING AND LABELING;

EID: 65749100356     PISSN: 18244785     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (79)

1. Thompson M, Wall DM, Hicks RJ, Prince HM. In vivo tracking for cell therapies. Q J Nucl Med Mol Imaging 2005;49:339-48.
2. Cummings JR, Keshav S, Travis SP. Medical management of Crohn's disease. BMJ 2008;336:1062-6.
3. Sizova L. Approaches to the treatment of early rheumatoid arthritis with disease-modifying antirheumatic drugs. Br J Clin Pharmacol 2008;66:173-8.
4. Zhang SJ, Wu JC. Comparison of imaging techniques for tracking cardiac stem cell therapy. J Nucl Med 2007;48:1916-9.
5. Thurlings RM, Vos K, Wijbrandts CA, Zwinderman AH, Gerlag DM, Tak PP. Synovial tissue response to rituximab: mechanism of action and identification of biomarkers of response. Ann Rheum Dis 2008;67:917-25.
6. Kircher MF, Grimm J, Swirski FK, Libby P, Gerszten RE, Allport JR et al. Noninvasive in vivo imaging of monocyte trafficking to atherosclerotic lesions. Circulation 2008; 117:388-95.
7. Fujita J, Mori M, Kawada H, Ieda Y, Tsuma M, Matsuzaki Y et al. Administration of granulocyte colony-stimulating factor after myocardial infarction enhances the recruitment of hematopoietic stem cell-derived myofibroblasts and contributes to cardiac repair. Stem Cells 2007;25:2750-9.
8. Banchereau J, Palucka AK. Dendritic cells as therapeutic vaccines against cancer. Nat Rev Immunol 2005;5:296-306.
9. Prince HM, Wall DM, Ritchie D, Honemann D, Harrrison S, Quach H et al. In vivo tracking of dendritic cells in patients with multiple myeloma. J Immunother 2008;31:166-79.
10. 99mTc-HMPAO at very high specific radioactivity. Nucl Med Biol 2007;34:933-8.
11. Grage-Griebenow E, Flad HD, Ernst M. Heterogeneity of human peripheral blood monocyte subsets. J Leukoc Biol 2001;69:11-20.
12. Fogg DK, Sibon C, Miled C, Jung S, Aucouturier P, Littman DR et al. A clonogenic bone marrow progenitor specific for macrophages and dendritic cells. Science 2006;311:83-7.
13. Whitelaw DM. Observations on human monocyte kinetics after pulse labeling. Cell Tissue Kinet 1972;5:311-7.
14. Figdor CG, Bont WS, Touw I, de Roos J, Roosnek EE, de Vries JE. Isolation of functionally different human monocytes by counter-flow centrifugation elutriation. Blood 1982;60:46-53.
15. Akiyama Y, Stevenson GW, Schlick E, Matsushima K, Miller PJ, Stevenson HC. Differential ability of human blood monocyte subsets to release various cytokines. J Leukoc Biol 1985;37:519-30
16. Akiyama Y, Miller PJ, Thurman GB, Neubauer RH, Oliver C, Favilla T et al. Characterization of a human blood monocyte subset with low peroxidase activity. J Clin Invest 1983;72:1093-105.
17. Tacke F, Randolph GJ. Migratory fate and differentiation of blood monocyte subsets. Immunobiology 2006;211:609-18.
18. Passlick B, Flieger D, Ziegler-Heitbrock HW. Identification and characterization of a novel monocyte subpopulation in human peripheral blood. Blood 1989;74:2527-34.
19. Ziegler-Heitbrock HW, Fingerle G, Strobel M, Schraut W, Stelter F, Schutt C et al. The novel subset of CD14+/CD16+ blood monocytes exhibits features of tissue macrophages. Eur J Immunol 1993;23:2053-8.
20. Ziegler-Heitbrock HW. Heterogeneity of human blood monocytes: the CD14+ CD16+ subpopulation. Immunol Today 1996;17:424-8.
21. Thieblemont N, Weiss L, Sadeghi HM, Estcourt C, Haeffner-Cavaillon N. CD14lowCD16high: a cytokine-producing monocyte subset which expands during human immunodeficiency virus infection. Eur J Immunol 1995;25:3418-24.
22. Strauss-Ayali D, Conrad SM, Mosser DM. Monocyte subpopulations and their differentiation patterns during infection. J Leukoc Biol 2007;82:244-52.
23. Ziegler-Heitbrock L. The CD14+ CD16+ blood monocytes: their role in infection and inflammation. J Leukoc Biol 2007;81:584-92.
24. Baeten D, Boots AM, Steenbakkers PG, Elewaut D, Bos E, Verheijden GF et al. Human cartilage gp-39+,CD16+ monocytes in peripheral blood and synovium: correlation with joint destruction in rheumatoid arthritis. Arthritis Rheum 2000;43:1233-43.
25. Springer TA. Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm. Cell 1994;76:301-14.
26. Gerard C, Rollins BJ. Chemokines and disease. Nat Immunol 2001;2:108-15.
27. Schenkel AR, Mamdouh Z, Muller WA. Locomotion of monocytes on endothelium is a critical step during extravasation. Nat Immunol 2004;5:393-400.
28. Imhof BA, Aurrand-Lions M. Adhesion mechanisms regulating the migration of monocytes. Nat Rev Immunol 2004;4:432-44.
29. Puri KD, Finger EB, Springer TA. The faster kinetics of L-selectin than of E-selectin and P-selectin rolling at comparable binding strength. J Immunol 1997;158:405-13.
30. Finger EB, Puri KD, Alon R, Lawrence MB, von Andrian UH, Springer TA. Adhesion through L-selectin requires a threshold hydrodynamic shear. Nature 1996;379:266-9.
31. Luscinskas FW, Lawler J. Integrins as dynamic regulators of vascular function. FASEB J 1994;8:929-38.
32. Luscinskas FW, Kansas GS, Ding H, Pizcueta P, Schleiffenbaum BE, Tedder TF et al. Monocyte rolling, arrest and spreading on IL-4-activated vascular endothelium under flow is mediated via sequential action of L-selectin, beta 1-integrins, and beta 2-integrins. J Cell Biol 1994;125:1417-27.
33. Muller WA, Weigl SA, Deng X, Phillips DM. PECAM-1 is required for transendothelial migration of leukocytes. J Exp Med 1993;178:449-60.
34. Liao F, Huynh HK, Eiroa A, Greene T, Polizzi E, Muller WA. Migration of monocytes across endothelium and passage through extracellular matrix involve separate molecular domains of PECAM-1. J Exp Med 1995;182:1337-43.
35. Xu H, Manivannan A, Crane IJ, Dawson R, Liversidge J. Critical but divergent roles for CD62L and CD44 in directing blood monocyte trafficking in vivo during inflammation. Blood 2008; 112:1166-74.
36. Weber C, Belge KU, von Hundelshausen P, Draude G, Steppich B, Mack M et al. Differential chemokine receptor expression and function in human monocyte subpopulations. J Leukoc Biol 2000;67:699-704.
37. Ancuta P, Rao R, Moses A, Mehle A, Shaw SK, Luscinskas FW et al. Fractalkine preferentially mediates arrest and migration of CD16+ monocytes. J Exp Med 2003;197:1701-7.
38. Geissmann F, Jung S, Littman DR. Blood monocytes consist of two principal subsets with distinct migratory properties. Immunity 2003;19:71-82.
39. Gerszten RE, Garcia-Zepeda EA, Lim YC, Yoshida M, Ding HA, Gimbrone MA, Jr. et al. MCP-1 and IL-8 trigger firm adhesion of monocytes to vascular endothelium under flow conditions. Nature 1999;398:718-23.
40. Kurth I, Willimann K, Schaerli P, Hunziker T, Clark-Lewis I, Moser B. Monocyte selectivity and tissue localization suggests a role for breast and kidney-expressed chemokine (BRAK) in macrophage development. J Exp Med 2001;194:855-61.
41. Serbina NV, Pamer EG. Monocyte emigration from bone marrow during bacterial infection requires signals mediated by chemokine receptor CCR2. Nat Immunol 2006;7:311-7.
42. Ross R. Atherosclerosis - an inflammatory disease. N Engl J Med 1999;340:115-26.
43. Sanz J, Moreno PR, Fuster V. Update on advances in atherothrombosis. Nat Clin Pract Cardiovasc Med 2007;4:78-89.
44. Tacke F, Alvarez D, Kaplan TJ, Jakubzick C, Spanbroek R, Llodra J et al. Monocyte subsets differentially employ CCR2, CCR5, and CX3CR1 to accumulate within atherosclerotic plaques. J Clin Invest 2007;117:185-94.
45. Sweeney SE, Firestein GS. Rheumatoid arthritis: regulation of synovial inflammation. Int J Biochem Cell Biol 2004;36:372-8.
46. Kunkel EJ, Butcher EC. Chemokines and the tissue-specific migration of lymphocytes. Immunity 2002;16:1-4.
47. Tak PP. Chemokine inhibition in inflammatory arthritis. Best Pract Res Clin Rheumatol 2006;20:929-39.
48. 99mTc-HMPAO-labeled monocytes in patients with rheumatoid arthritis. J Nucl Med 2008;49:1380-5.
49. Hartung D, Petrov A, Haider N, Fujimoto S, Blankenberg F, Fujimoto A et al. Radiolabeled monocyte chemotactic protein 1 for the detection of inflammation in experimental atherosclerosis. J Nucl Med 2007;48:1816-21.
50. Buscombe JR. The future of infection imaging. Q J Nucl Med Mol Imaging 2006;50:99-103.
51. Hou JC, Pessin JE. Ins (endocytosis) and outs (exocytosis) of GLUT4 trafficking. Curr Opin Cell Biol 2007;19:466-73.
52. Huang S, Czech MP. The GLUT4 glucose transporter. Cell Metab 2007;5:237-52.
53. 18F]fluorodeoxyglucose in human monocyte-macrophages in vitro. Eur J Nucl Med Mol Imaging 2003;30:267-73.
54. Gross MD, Rubello D, editors. Advances in PET. Q J Nucl Med Mol Imaging 2008;52(Part II).
55. Ritchie D, Mileshkin L, Wall D, Bartholeyns J, Thompson M, Coverdale J et al. In vivo tracking of macrophage activated killer cells to sites of metastatic ovarian carcinoma. Cancer Immunol Immunother 2007;56:155-63.
56. Paik JY, Lee KH, Choe YS, Choi Y, Kim BT. Augmented 18F-FDG uptake in activated monocytes occurs during the priming process and involves tyrosine kinases and protein kinase C. J Nucl Med 2004;45:124-8.
57. 18F-FDG uptake in human endothelial cells in vitro. J Nucl Med 2004;45:455-60.
58. 18F-FDG-labeled leukocytes. Q J Nucl Med Mol Imaging 2006; 50:143-6.
59. 18F] fluoro-2-deoxy-D-glucose as a potential in vitro agent for labelling human granulocytes for clinical studies by positron emission tomography. Int J Rad Appl Instrum B 1992;19:183-90.
60. Jacobs AE, Oosterhof A, Veerkamp JH. 2-Deoxy-D-glucose uptake in cultured human muscle cells. Biochim Biophys Acta 1990;1051:230-6.
61. Newsholme EA, Rolleston FS, Taylor K. Factors affecting the glucose 6-phosphate inhibition of hexokinase from cerebral cortex tissue of the guinea pig. Biochem J 1968;106:193-201.
62. Whitesell RR, Ardehali H, Beechem JM, Powers AC, Van der Meer W, Perriott LM et al. Compartmentalization of transport and phosphorylation of glucose in a hepatoma cell line. Biochem J 2005;386:245-53.
63. Whitesell RR, Ardehali H, Printz RL, Beechem JM, Knobel SM, Piston DW et al. Control of glucose phosphorylation in L6 myotubes by compartmentalization, hexokinase, and glucose transport. Biochem J 2003;370:47-56.
64. 18F-FDG labelling of human leukocytes. Nucl Med Commun 2000;21:691-4.
65. 18F] fluoro-D-glucose-labeled white blood cells. Mol Imaging Biol 2003;5:271-7.
66. 111In-oxine-labeled leukocytes for detection of infection. Radiology 2006;238:978-87.
67. Ballinger JR, Gnanasegaran G. Radiolabelled leukocytes for imaging inflammation: how radiochemistry affects clinical use. Q J Nucl Med Mol Imaging 2005;49:308-18.
68. Thakur ML, Segal AW, Louis L, Welch MJ, Hopkins J, Peters TJ. Indium-111-labeled cellular blood components: mechanism of labeling and intracellular location in human neutrophils. J Nucl Med 1977;18:1022-6.
69. Thakur ML, Lavender JF, Arnot RN, Silvester DJ, Segal AW. Indium-111-labeled autologous leukocytes in man. J Nucl Med 1977;18:1014-21.
70. Green MA, Huffman JC. The molecular structure of indium oxine. J Nucl Med 1988;29:417-20.
71. Daniel KG, Chen D, Yan B, Dou QP. Copper-binding compounds as proteasome inhibitors and apoptosis inducers in human cancer. Front Biosci 2007;12:135-44.
72. Martinez-Larranaga MR, Anadon A, Fernandez-Cruz ML, Diaz MJ, Martinez MA, Frejo MT et al. Cytotoxicity in pig hepatocytes induced by 8-quinolinol, chloramine-T and natamycin. J Vet Pharmacol Ther 2000;23:37-44.
73. ten Berge RJ, Natarajan AT, Hardeman MR, van Royen EA, Schellekens PT. Labeling with indium-111 has detrimental effects on human lymphocytes: concise communication. J Nucl Med 1983;24:615-20.
74. Kuyama J, McCormack A, George AJ, Heelan BT, Osman S, Batchelor JR et al. Indium-111 labelled lymphocytes: isotope distribution and cell division. Eur J Nucl Med 1997;24:488-96.
75. Sparshott SM, Sharma H, Kelly JD, Ford WL. Factors influencing the fate of 111-indium-labelled lymphocytes after transfer to syngeneic rats. J Immunol Methods 1981;41:303-20.
76. Davies JR, Rudd JH, Weissberg PL, Narula J. Radionuclide imaging for the detection of inflammation in vulnerable plaques. J Am Coll Cardiol 2006;47:C57-C68.
77. Doherty DE, Downey GP, Worthen GS, Haslett C, Henson PM. Monocyte retention and migration in pulmonary inflammation. Requirement for neutrophils. Lab invest 1988;59:200-13.
78. Doherty DE, Hirose N, Zagarella L, Cherniack RM. Prolonged monocyte accumulation in the lung during bleomycin-induced pulmonary fibrosis. A noninvasive assessment of monocyte kinetics by scintigraphy. Lab Invest 1992;66:231-42.
79. Grimm MC, Pullman WE, Bennett GM, Sullivan PJ, Pavli P, Doe WF. Direct evidence of monocyte recruitment to inflammatory bowel disease mucosa. J Gastroenterol Hepatol 1995;10:387-95.