Fatal case of deer tick virus encephalitis

New England Journal of Medicine

Volumn 360, Issue 20, 2009, Pages 2099-2107

  Tavakoli, Norma P ^a,b,g   Wang, Heng ^a   Dupuis, Michelle ^a   Hull, Rene ^a   Ebel, Gregory D ^c   Gilmore, Emily J ^d,f   Faust, Phyllis L ^e,f  

^a WADSWORTH CENTER   (United States)

^b STATE UNIVERSITY OF NEW YORK   (United States)

^c UNIVERSITY OF NEW MEXICO SCHOOL OF MEDICINE   (United States)

^d Och Spine at New York Presbyterian Hospitals   (United States)

^e NewYork Presbyterian Hospital   (United States)

^f NEW YORK PRESBYTERIAN HOSPITAL   (United States)

^g NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACICLOVIR; AMOXICILLIN PLUS CLAVULANIC ACID; ANTIBIOTIC AGENT; FLUDARABINE; NONSTEROID ANTIINFLAMMATORY AGENT; NUCLEIC ACID; DIAGNOSTIC AGENT; VIRUS ANTIBODY;

ADULT; ARTICLE; AUTOPSY; BASAL GANGLION; BRAIN INFECTION; BRAIN STEM; CASE REPORT; CEREBELLUM; CHRONIC LYMPHATIC LEUKEMIA; CHRONIC SINUSITIS; DEER TICK VIRUS; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; LYMPHOCYTOMA; MALE; MENINGOENCEPHALITIS; NERVE CELL; NUCLEIC ACID ANALYSIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SEQUENCE ANALYSIS; SPINAL CORD; THALAMUS; TICK BORNE ENCEPHALITIS FLAVIVIRUS; TISSUE SECTION; VIRUS ENCEPHALITIS; VIRUS IDENTIFICATION; ANIMAL; BRAIN; DNA SEQUENCE; FATALITY; GENETICS; ISOLATION AND PURIFICATION; IXODES; MIDDLE AGED; PATHOLOGY; PHYLOGENY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TICK BORNE ENCEPHALITIS; VIROLOGY;

ANIMALS; ANTIBODIES, VIRAL; BRAIN; ENCEPHALITIS VIRUSES, TICK-BORNE; ENCEPHALITIS, TICK-BORNE; FATAL OUTCOME; HUMANS; IMMUNOHISTOCHEMISTRY; IXODES; MALE; MIDDLE AGED; PHYLOGENY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS, DNA;

EID: 65649150678     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMoa0806326     Document Type: Article

References (28)

1. Telford SR III, Armstrong PM, Katavolos P, et al. A new tick-borne encephalitislike virus infecting New England deer ticks, Ixodes dammini. Emerg Infect Dis 1997;3:165-170
2. Kuno G, Artsob H, Karabatos N, Tsuchiya KR, Chang GJJ. Genomic sequencing of deer tick virus and phylogeny of Powassan-related viruses of North America. Am J Trop Med Hyg 2001;65:671-676
3. Beasley DWC, Suderman MT, Holbrook MR, Barrett ADT. Nucleotide sequencing and serological evidence that the recently recognized deer tick virus is a genotype of Powassan virus. Virus Res 2001;79:81-89
4. Ebel GD, Spielman A, Telford SR III. Phylogeny of North American Powassan virus. J Gen Virol 2001;82:1657-1665
5. Charrel RN, Attoui H, Butenko AM, et al. Tick-borne virus diseases of human interest in Europe. Clin Microbiol Infect 2004;10:1040-1055
6. Artsob H. Powassan encephalitis. In: Monath TP, ed. The arboviruses: epidemiology and ecology. Boca Raton, FL: CRC Press, 1988:29-49.
7. Gritsun TS, Nuttall PA, Gould EA. Tick-borne flaviviruses. Adv Virus Res 2003;61:317-371
8. Burke DS, Monath TP. Flaviviruses. In: Knipe DM, Howley PM, Griffin DE, Lamb RA, Martin MA, Roizman B, eds. Fields virology. 4th ed. Philadelphia: Lippincott Williams & Wilkins, 2001:1043-1126
9. Ebel GD, Campbell EN, Goethert HK, Spielman A, Telford SR III. Enzootic transmission of deer tick virus in New England and Wisconsin sites. Am J Trop Med Hyg 2000;63:36-42.
10. Ebel GD, Foppa I, Spielman A, Telford SR III. A focus of deer tick virus transmission in the northcentral United States. Emerg Infect Dis 1999;5:570-574
11. Scaramozzino N, Crance J-M, Jouan A, DeBriel DA, Stoll F, Garin D. Comparison of flavivirus universal primer pairs and development of a rapid, highly sensitive heminested reverse transcription-PCR assay for detection of flavivirus targeted to a conserved region of the NS5 gene sequences. J Clin Microbiol 2001;39:1922-1927
12. Tavakoli NP, Tobin EH, Wong SJ, et al. Identification of dengue virus in respiratory specimens from a patient who had recently traveled from a region where dengue virus is endemic. J Clin Microbiol 2007;45:1523-1527
13. Pfeffer M, Proebster B, Kinney RM, Kaaden O-R. Genus-specific detection of alphaviruses by a semi-nested reverse transcription-polymerase chain reaction. Am J Trop Med Hyg 1997;57:709-718
14. Saitou N, Nei M. The neighbor-joining method: a new method for reconstructing phylogenetic trees. Mol Biol Evol 1987;4:406-425
15. Tamura K, Nei M, Kumar S. Prospects for inferring very large phylogenies by using the neighbor-joining method. Proc Natl Acad Sci U S A 2004;101:11030-11035
16. Tamura K, Dudley J, Nei M, Kumar S. MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) software version 4.0. Mol Biol Evol 2007;24:1596-1599
17. Gholam BA, Puksa S, Provias JP. Powassan encephalitis: a case report with neuropathology and literature review. CMAJ 1999;161:1419-1422
18. Embil JA, Camfield P, Artsob H, Chase DP. Powassan virus encephalitis resembling herpes simplex encephalitis. Arch Intern Med 1983;143:341-343
19. Wilson MS, Wherrett BA, Mahday MS. Powassan virus meningoencephalitis: a case report. Can Med Assoc J 1979;121:320-323
20. Goldfield M, Austin SM, Black HC, Taylor BF, Altman R. A non-fatal human case of Powassan virus encephalitis. Am J Trop Med Hyg 1973;22:78-81.
21. McLean DM, Donohue WL. Powassan virus: isolation of virus from a fatal case of encephalitis. Can Med Assoc J 1959;80:708-711
22. McLean DM, McQueen EJ, Petite HE, MacPherson LW, Scholten TH, Ronald K. Powassan virus: field investigations in northern Ontario, 1959 to 1961. CMAJ 1962;86:971-974
23. Love S, Wiley CA. Viral infections. In: Love S, Louis DW, Ellison DW, eds. Greenfield's neuropathology. 8th ed. London: Hodder Arnold, 2008:1323-1333
24. Penn RG, Guarner J, Sejvar JJ, et al. Persistent neuroinvasive West Nile virus infection in an immunocompromised patient. Clin Infect Dis 2006;42:680-683
25. Ravindra KV, Freifeld AG, Kalil AC, et al. West Nile virus-associated encephalitis in recipients of renal and pancreas transplants: case series and literature review. Clin Infect Dis 2004;38:1257-1260
26. Gelpi E, Preusser M, Garzuly F, Holzmann H, Heinz FX, Budka H. Visualization of Central European tick-borne encephalitis infection in fatal human cases. J Neuropathol Exp Neurol 2005;64:506-512
27. Gelpi E, Preusser M, Laggner U, et al. Inflammatory response in human tick-borne encephalitis: analysis of postmortem brain tissue. J Neurovirol 2006;12:322-327
28. Thompson C, Spielman A, Krause PJ. Coinfecting deer-associated zoonoses: Lyme disease, babesiosis, and ehrlichiosis. Clin Infect Dis 2001;33:676-685