메뉴 건너뛰기




Volumn 66, Issue 10, 2009, Pages 899-907

Treatment of Alzheimer's disease in the long-term-care setting

Author keywords

Alzheimer disease; Central nervous system drugs; Donepezil; Galantamine; Long term care facilities; Mechanism of action; Memantine; Parasympathomimetic agents; Rivastigmine; Toxicity

Indexed keywords

DONEPEZIL; GALANTAMINE; MEMANTINE; RIVASTIGMINE;

EID: 65649137775     PISSN: 10792082     EISSN: None     Source Type: Journal    
DOI: 10.2146/ajhp070622     Document Type: Article
Times cited : (38)

References (59)
  • 1
    • 0042023711 scopus 로고    scopus 로고
    • Alzheimer disease in the US population: Prevalence estimates using the 2000 census
    • DOI 10.1001/archneur.60.8.1119
    • Hebert LE, Scherr PA, Bienias JL et al. Alzheimer disease in the US population: prevalence estimates using the 2000 census. Arch Neurol. 2003; 60:1119-1122 (Pubitemid 36975801)
    • (2003) Archives of Neurology , vol.60 , Issue.8 , pp. 1119-1122
    • Hebert, L.E.1    Scherr, P.A.2    Bienias, J.L.3    Bennett, D.A.4    Evans, D.A.5
  • 3
    • 0031791222 scopus 로고    scopus 로고
    • An integrated approach to the management of Alzheimer's disease: Assessing cognition, function and behaviour
    • Galasko D. An integrated approach to the management of Alzheimer's disease: assessing cognition, function and behavior. Eur J Neurol. 1998; 5(suppl 4):S9-S17. (Pubitemid 28550113)
    • (1998) European Journal of Neurology , vol.5 , Issue.SUPPL. 4
    • Galasko, D.1
  • 5
    • 0035661596 scopus 로고    scopus 로고
    • A randomized, double-blind, placebo-controlled study of the efficacy and safety of donepezil in patients with Alzheimer's disease in the nursing home setting
    • DOI 10.1046/j.1532-5415.2001.t01-1-49266.x
    • Tariot PN, Cummings JL, Katz IR et al. A randomized, double-blind, placebo-controlled study of the efficacy and safety of donepezil in patients with Alzheimer's disease in the nursing home setting. J Am Geriatr Soc. 2001; 49:1590-1599 (Pubitemid 34007984)
    • (2001) Journal of the American Geriatrics Society , vol.49 , Issue.12 , pp. 1590-1599
    • Tariot, P.N.1    Cummings, J.L.2    Katz, I.R.3    Mintzer, J.4    Perdomo, C.A.5    Schwam, E.M.6    Whalen, E.7
  • 6
    • 33645741379 scopus 로고    scopus 로고
    • Donepezil in patients with severe Alzheimer's disease: Double-blind, parallel-group, placebo-controlled study
    • [Erratum, Lancet. 2006; 367:1980.] [Erratum, Lancet. 2006; 368:1650.]
    • Winblad B, Kilander L, Eriksson S et al. Donepezil in patients with severe Alzheimer's disease: double-blind, parallel-group, placebo-controlled study. Lancet. 2006; 367:1057-65. [Erratum, Lancet. 2006; 367:1980.] [Erratum, Lancet. 2006; 368:1650.]
    • (2006) Lancet , vol.367 , pp. 1057-1065
    • Winblad, B.1    Kilander, L.2    Eriksson, S.3
  • 7
    • 0032983786 scopus 로고    scopus 로고
    • 9M-best study (benefit and efficacy in severly demented patients during treatment with memantine)
    • DOI 10.1002/(SICI)1099-1166(199902)14:2<135::AID-GPS906>3.0.CO;2-0
    • Winblad B, Poritis N. Memantine in severe dementia: results of the 9M-Best Study (Benefit and efficacy in severely demented patients during treatment with memantine). Int J Geriatr Psychiatry. 1999; 14:135-146 (Pubitemid 29110331)
    • (1999) International Journal of Geriatric Psychiatry , vol.14 , Issue.2 , pp. 135-146
    • Winblad, B.1    Poritis, N.2
  • 9
    • 7644237621 scopus 로고    scopus 로고
    • Long-term effects of rivastigmine treatment on neuropsychiatric and behavioral disturbances in nursing home residents with moderate to severe Alzheimer's disease: Results of a 52-week open-label study
    • DOI 10.1185/030079904125004204
    • Aupperle PM, Koumaras B, Chen M et al. Long-term effects of rivastigmine treatment on neuropsychiatric and behavioral disturbances in nursing home residents with moderate to severe Alzheimer's disease: results of a 52-week open-label study. Curr Med Res Opin. 2004; 20:1605-1612 (Pubitemid 39457548)
    • (2004) Current Medical Research and Opinion , vol.20 , Issue.10 , pp. 1605-1612
    • Aupperle, P.M.1    Koumaras, B.2    Chen, M.3    Rabinowicz, A.4    Mirski, D.5
  • 10
    • 41049104686 scopus 로고    scopus 로고
    • Current pharmacologic treatment of dementia: A clinical practice guideline from the American College of Physicians and the American Academy of Family Physicians
    • Qaseem A, Snow V, Cross JT Jr et al. Current pharmacologic treatment of dementia: a clinical practice guideline from the American College of Physicians and the American Academy of Family Physicians. Ann Intern Med. 2008; 148:370-378
    • (2008) Ann Intern Med , vol.148 , pp. 370-378
    • Qaseem, A.1    Snow, V.2    Cross Jr., J.T.3
  • 11
    • 0021271971 scopus 로고
    • Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA work group under the auspices of Department of Health and Human Services Task Force on Alzheimer's disease
    • McKhann G, Drachman D, Folstein M et al. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology. 1984; 34:939-944 (Pubitemid 14076461)
    • (1984) Neurology , vol.34 , Issue.7 , pp. 939-944
    • McKhann, G.1    Drachman, D.2    Folstein, M.3
  • 12
    • 39749199492 scopus 로고
    • American Psychiatric Association. Washington, DC: American Psychiatric Association
    • American Psychiatric Association. Diagnostic and statistical manual of mental disorders, 4th ed. Washington, DC: American Psychiatric Association; 1994:142, 684.
    • (1994) Diagnostic and Statistical Manual of Mental Disorders, 4th Ed. , vol.142 , pp. 684
  • 15
    • 0002815550 scopus 로고    scopus 로고
    • American Medical Directors Association. Columbia, MD: American Medical Directors Association
    • American Medical Directors Association. Dementia: clinical practice guideline 1998. Columbia, MD: American Medical Directors Association; 1998.
    • (1998) Dementia: Clinical Practice Guideline 1998
  • 16
    • 0141459644 scopus 로고    scopus 로고
    • Missing the diagnosis: Senile dementia in patients admitted to nursing homes
    • DOI 10.1080/02813430310001798
    • Nygaard HA, Ruths S. Missing the diagnosis: senile dementia in patients admitted to nursing homes. Scand J Prim Health Care. 2003; 21:148-152 (Pubitemid 37174003)
    • (2003) Scandinavian Journal of Primary Health Care , vol.21 , Issue.3 , pp. 148-152
    • Nygaard, H.A.1    Ruths, S.2
  • 17
    • 0037326297 scopus 로고    scopus 로고
    • The recognition of dementia in "non-EMI" nursing home residents in South East England
    • Macdonald AJ, Carpenter GI. The recognition of dementia in "non-EMI" nursing home residents in South East England. Int J Geriatr Psychiatry. 2003; 18:105-108
    • (2003) Int J Geriatr Psychiatry , vol.18 , pp. 105-108
    • Macdonald, A.J.1    Carpenter, G.I.2
  • 18
    • 32444436912 scopus 로고    scopus 로고
    • Improved evaluation and management of cognitive impairment: Results of a comprehensive intervention in long-term care
    • DOI 10.1016/j.jamda.2005.06.008, PII S1525861005004378
    • Barton C, Miller B, Yaffe K. Improved evaluation and management of cognitive impairment: results of a comprehensive intervention in long-term care. J Am Med Dir Assoc. 2006; 7:84-89 (Pubitemid 43224466)
    • (2006) Journal of the American Medical Directors Association , vol.7 , Issue.2 , pp. 84-89
    • Barton, C.1    Miller, B.2    Yaffe, K.3
  • 19
    • 0029086231 scopus 로고
    • Validation of the Minimum Data Set Cognitive Performance Scale: Agreement with the Mini-Mental State Examination
    • Hartmaier SL, Sloane PD, Guess HA et al. Validation of the Minimum Data Set Cognitive Performance Scale: agreement with the Mini-Mental State Examination. J Gerontol Biol Sci Med Sci. 1995; 50:M128-33.
    • (1995) J Gerontol Biol Sci Med Sci , vol.50
    • Hartmaier, S.L.1    Sloane, P.D.2    Guess, H.A.3
  • 22
    • 0034720864 scopus 로고    scopus 로고
    • A 5-month, randomized, placebo-controlled trial of galantamine in AD
    • Tariot PN, Solomon PR, Morris JC et al. A 5-month, randomized, placebo-controlled trial of galantamine in AD. Neurology. 2000; 54:2269-2276
    • (2000) Neurology , vol.54 , pp. 2269-2276
    • Tariot, P.N.1    Solomon, P.R.2    Morris, J.C.3
  • 25
    • 85077294808 scopus 로고    scopus 로고
    • Galantamine delays nursing home transfers in Alzheimer's disease (AD) patients residing in assisted living facilities
    • Abstract
    • Shua-Haim JR, Smith JM, Patel SR et al. Galantamine delays nursing home transfers in Alzheimer's disease (AD) patients residing in assisted living facilities. Alzheimers Demen. 2006; 2:S636. Abstract.
    • (2006) Alzheimers Demen , vol.2
    • Shua-Haim, J.R.1    Smith, J.M.2    Patel, S.R.3
  • 26
    • 0021520020 scopus 로고
    • A new rating scale for Alzheimer's disease
    • Rosen WG, Mohs RC, Davis KL. A new rating scale for Alzheimer's disease. Am J Psychiatry. 1984; 141:1356-1364
    • (1984) Am J Psychiatry , vol.141 , pp. 1356-1364
    • Rosen, W.G.1    Mohs, R.C.2    Davis, K.L.3
  • 29
    • 0027425211 scopus 로고
    • The Clinical Dementia Rating (CDR): Current version and scoring rules
    • Morris JC. The Clinical Dementia Rating Scale (CDR): current version and scoring rules. Neurology. 1993; 43:2412-2414 (Pubitemid 23346995)
    • (1993) Neurology , vol.43 , Issue.11 , pp. 2412-2414
    • Morris, J.C.1
  • 30
    • 0000238671 scopus 로고
    • Clinical global impressions
    • Guy W, ed. Rockville, MD: National Institutes of Health
    • Guy W. Clinical global impressions. In: Guy W, ed. ECDEU assessment manual for psychopharmacology. Rockville, MD: National Institutes of Health; 1976:217-220
    • (1976) ECDEU Assessment Manual for Psychopharmacology , pp. 217-220
    • Guy, W.1
  • 31
    • 0016823810 scopus 로고
    • "Mini-mental state." A practical method for grading the cognitive state of patients for the clinician
    • Folstein MF, Folstein SE, McHugh PR. "Mini-mental state." A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res. 1975; 12:189-198
    • (1975) J Psychiatr Res , vol.12 , pp. 189-198
    • Folstein, M.F.1    Folstein, S.E.2    McHugh, P.R.3
  • 36
    • 30344444750 scopus 로고    scopus 로고
    • A 24-week open-label extension study of memantine in moderate to severe alzheimer disease
    • DOI 10.1001/archneur.63.1.49
    • Reisberg B, Doody R, Stöffler A et al. A 24-week open-label extension study of memantine in moderate-to-severe Alzheimer disease. Arch Neurol. 2006; 63:49-54. (Pubitemid 43063861)
    • (2006) Archives of Neurology , vol.63 , Issue.1 , pp. 49-54
    • Reisberg, B.1    Doody, R.2    Stoffler, A.3    Schmitt, F.4    Ferris, S.5    Mobius, H.J.6
  • 37
    • 0034463115 scopus 로고    scopus 로고
    • An efficacy and safety analysis of Exelon in Alzheimer's disease patients with concurrent vascular risk factors
    • DOI 10.1046/j.1468-1331.2000.00046.x
    • Farlow M, Anand R, Messina J Jr et al. A 52-week study of the efficacy of rivastigmine in patients with mild to moderately severe Alzheimer's disease. Eur Neurol. 2000; 44:238-241 (Pubitemid 32260563)
    • (2000) European Journal of Neurology , vol.7 , Issue.2 , pp. 159-169
    • Kumar, V.1    Anand, R.2    Messina, J.3    Hartman, R.4    Veach, J.5
  • 38
    • 84903220316 scopus 로고    scopus 로고
    • Long-term outcomes of galantamine treatment in patients with Alzheimer disease
    • DOI 10.1176/appi.ajgp.12.5.473
    • Lyketsos CG, Reichman WE, Kershaw P et al. Long-term outcomes of galantamine treatment in patients with Alzheimer disease. Am J Geriatr Psychiatry. 2004; 12:473-482 (Pubitemid 39181062)
    • (2004) American Journal of Geriatric Psychiatry , vol.12 , Issue.5 , pp. 473-482
    • Lyketsos, C.G.1    Reichman, W.E.2    Kershaw, P.3    Zhu, Y.4
  • 39
    • 41049111771 scopus 로고    scopus 로고
    • Effectiveness of cholinesterase inhibitors and memantine for treating dementia: Evidence review for a clinical practice guideline
    • Raina P, Santaguida P, Ismaila A et al. Effectiveness of cholinesterase inhibitors and memantine for treating dementia: evidence review for a clinical practice guideline. Ann Intern Med. 2008; 148:379-397
    • (2008) Ann Intern Med , vol.148 , pp. 379-397
    • Raina, P.1    Santaguida, P.2    Ismaila, A.3
  • 40
    • 0035209309 scopus 로고    scopus 로고
    • The Alzheimer's disease assessment scale: Evaluation of psychometric properties and patterns of cognitive decline in multicenter clinical trials of mild to moderate Alzheimer's disease
    • DOI 10.1097/00002093-200110000-00003
    • Doraiswamy PM, Kaiser L, Bieber F et al. The Alzheimer's Disease Assessment Scale: evaluation of psychometric properties and patterns of cognitive decline in multicenter clinical trials of mild to moderate Alzheimer's disease. Alzheimer Dis Assoc Disord. 2001; 15:174-183 (Pubitemid 33117033)
    • (2001) Alzheimer Disease and Associated Disorders , vol.15 , Issue.4 , pp. 174-183
    • Doraiswamy, P.M.1    Kaiser, L.2    Bieber, F.3    Garman, R.L.4
  • 41
    • 23644441615 scopus 로고    scopus 로고
    • An assessment of the diagnosis and management of dementia in nursing homes
    • Mann JL, Evans TS, O'Hara LM. An assessment of the diagnosis and management of dementia in nursing homes. Consult Pharm. 2005; 20:306-312 (Pubitemid 41132138)
    • (2005) Consultant Pharmacist , vol.20 , Issue.4 , pp. 306-312
    • Mann, J.L.1    Evans, T.S.2    O'Hara, L.M.3
  • 42
    • 33745932853 scopus 로고    scopus 로고
    • Patterns of cholinesterase-inhibitor use in the nursing home setting: A retrospective analysis
    • DOI 10.1016/j.amjopharm.2006.06.002, PII S1543594606000249
    • Dybicz SB, Keohane DJ, Erwin WG et al. Patterns of cholinesterase- inhibitor use in the nursing home setting: a retrospective analysis. Am J Geriatr Pharmacother. 2006; 4:154-160 (Pubitemid 44057811)
    • (2006) American Journal Geriatric Pharmacotherapy , vol.4 , Issue.2 , pp. 154-160
    • Dybicz, S.B.1    Keohane, D.J.2    Gary, E.W.3    McRae, T.4    Shah, S.N.5
  • 45
    • 65649118871 scopus 로고    scopus 로고
    • Titusville, NJ: Ortho-McNeil Neurologics, Inc.; Apr.
    • Razadyne (galantamine) package insert. Titusville, NJ: Ortho-McNeil Neurologics, Inc.; 2007 Apr.
    • (2007) Razadyne (Galantamine) Package Insert
  • 50
    • 21544467552 scopus 로고    scopus 로고
    • Cholinesterase inhibitors for patients with Alzheimer's disease: Systematic review of randomised clinical trials
    • Kaduszkiewicz H, Zimmermann T, Beck-Bornholdt HP et al. Cholinesterase inhibitors for patients with Alzheimer's disease: systematic review of randomised clinical trials. BMJ. 2005; 331:321-327 (Pubitemid 41113141)
    • (2005) British Medical Journal , vol.331 , Issue.7512 , pp. 321-323
    • Kaduszkiewicz, H.1    Zimmermann, T.2    Beck-Bornholdt, H.-P.3    Van, B.H.D.4
  • 51
    • 33750329955 scopus 로고    scopus 로고
    • Clinical practice with anti-dementia drugs: A consensus statement from British Association for Psychopharmacology
    • DOI 10.1177/0269881106068299
    • Burns A, O'Brien J, BAP Dementia Consensus group et al. Clinical practice with anti-dementia drugs: a consensus statement from British Association for Psychopharmacology. J Psychopharmacol. 2006; 20:732-755 (Pubitemid 44622739)
    • (2006) Journal of Psychopharmacology , vol.20 , Issue.6 , pp. 732-755
    • Burns, A.1    O'Brien, J.2
  • 52
    • 0035190585 scopus 로고    scopus 로고
    • Alzheimer's disease and other dementia in nursing homes: Levels of management and cost
    • DOI 10.1017/S1041610201007736
    • O'Brien JA, Caro JJ. Alzheimer's disease and other dementia in nursing homes: levels of management and cost. Int Psychogeriatr. 2001; 13:347-358 (Pubitemid 33101673)
    • (2001) International Psychogeriatrics , vol.13 , Issue.3 , pp. 347-358
    • O'Brien, J.A.1    Jaime, C.J.2
  • 53
    • 33644862199 scopus 로고    scopus 로고
    • Functional impairment, healthcare costs and the prevalence of institutionalisation in patients with Alzheimer's disease and other dementias
    • Hill J, Fillit H, Thomas SK et al. Functional impairment, healthcare costs and the prevalence of institutionalisation in patients with Alzheimer's disease and other dementias. Pharmacoeconomics. 2006; 24:265-280
    • (2006) Pharmacoeconomics , vol.24 , pp. 265-280
    • Hill, J.1    Fillit, H.2    Thomas, S.K.3
  • 54
    • 0000409280 scopus 로고    scopus 로고
    • Time and costs of managing specific disruptive behaviors in long-term care facilities: A descriptive study
    • Kleinman L, Schmier J, Rothman M et al. Time and costs of managing specific disruptive behaviors in long-term care facilities: a descriptive study. Consult Pharm. 2002; 17:497-507.
    • (2002) Consult Pharm , vol.17 , pp. 497-507
    • Kleinman, L.1    Schmier, J.2    Rothman, M.3
  • 56
    • 34548081204 scopus 로고    scopus 로고
    • Donepezil preserves cognition and global function in patients with severe Alzheimer disease
    • DOI 10.1212/01.wnl.0000266627.96040.5a, PII 0000611420070731000008
    • Black SE, Doody RS, Li H et al. Donepezil preserves cognition and global function in severe Alzheimer's disease patients. Neurology. 2007; 69:459-469 (Pubitemid 47450281)
    • (2007) Neurology , vol.69 , Issue.5 , pp. 459-469
    • Black, S.E.1    Doody, R.2    Li, H.3    McRae, T.4    Jambor, K.M.5    Xu, Y.6    Sun, Y.7    Perdomo, C.A.8    Richardson, S.9
  • 57
    • 0035964226 scopus 로고    scopus 로고
    • A 24-week, randomized, double-blind study of donepezil in moderate to severe Alzheimer's disease
    • Feldman H, Gauthier S, Hecker J et al. A 24-week, randomized, double-blind study of donepezil in moderate to severe Alzheimer's disease. Neurology. 2001; 57:613-620 (Pubitemid 32782987)
    • (2001) Neurology , vol.57 , Issue.4 , pp. 613-620
    • Feldman, H.1    Gauthier, S.2    Hecker, J.3    Vellas, B.4    Subbiah, P.5    Whalen, E.6
  • 58
    • 3042642016 scopus 로고    scopus 로고
    • Effects of galantamine on behavioural and psychological disturbances and caregiver burden in patients with Alzheimer's disease
    • DOI 10.1185/030079904125003890
    • Monsch AU, Giannakopoulos P, GAL-SUI-1 Study Group. Effects of galantamine on behavioural and psychological disturbances and caregiver burden in patients with Alzheimer's disease. Curr Med Res Opin. 2004; 20:931-938 (Pubitemid 38821532)
    • (2004) Current Medical Research and Opinion , vol.20 , Issue.6 , pp. 931-938
    • Monsch, A.U.1    Giannakopoulos, P.2
  • 59
    • 34248341709 scopus 로고    scopus 로고
    • EXACT: Rivastigmine improves the high prevalence of attention deficits and mood and behaviour symptoms in Alzheimer's disease
    • DOI 10.1111/j.1742-1241.2007.01387.x
    • Gauthier S, Juby A, Rehel B et al. EXACT: rivastigmine improves the high prevalence of attention deficits and mood and behaviour symptoms in Alzheimer's disease. Int J Clin Pract. 2007; 61: 886-895 (Pubitemid 46744076)
    • (2007) International Journal of Clinical Practice , vol.61 , Issue.6 , pp. 886-895
    • Gauthier, S.1    Juby, A.2    Rehel, B.3    Schecter, R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.