The treatment of CIN:What are the risks?

Cytopathology

Volumn 20, Issue 3, 2009, Pages 145-153

  Prendiville, W ^a  

^a ROYAL COLLEGE OF SURGEONS IN IRELAND   (Ireland)

Author keywords

Cervical intraepithelial neoplasia; CIN; Colposcopy; Pregnancy related morbidity; Treatment

Indexed keywords

ADENOCARCINOMA; CANCER INVASION; CANCER RISK; CANCER SURGERY; CANCER THERAPY; COLPOSCOPY; COUNSELING; HEALTH CARE COST; HISTOPATHOLOGY; HUMAN; MORBIDITY; OUTPATIENT CARE; PRACTICE GUIDELINE; PREGNANCY; PREMATURE LABOR; PRIORITY JOURNAL; REVIEW; SURGICAL TECHNIQUE; UTERINE CERVIX BIOPSY; UTERINE CERVIX CARCINOMA IN SITU;

BIOPSY; CERVICAL INTRAEPITHELIAL NEOPLASIA; COLPOSCOPY; FEMALE; GUIDELINES AS TOPIC; HUMANS; OBSTETRIC LABOR, PREMATURE; PREGNANCY; RISK FACTORS; UTERINE CERVICAL NEOPLASMS;

EID: 65649131241     PISSN: 09565507     EISSN: 13652303     Source Type: Journal    
DOI: 10.1111/j.1365-2303.2009.00669.x     Document Type: Review

References (47)

1. Sasieni P, Adams J, Cuzick J. Benefit of cervical screening at different ages: evidence from the UK audit of screening histories. Br J Cancer 2003 89 : 88 93. (Pubitemid 36897941)
2. Quinn M, Babb P, Jones J, Allen E. Effect of screening on incidence of and mortality from cancer of cervix in England: evaluation based on routinely collected statistics. BMJ 1999 318 : 904 8. (Pubitemid 29191925)
3. Peto J, Gilham C, Fletcher O, Matthews FE. The cervical cancer epidemic that screening has prevented in the UK. Lancet 2004 364 : 249 56. (Pubitemid 38942814)
4. Kitchener HC, Castle PE, Cox JT. Chapter 7: achievements and limitations of cervical cytology screening. Vaccine 2006 24 (Suppl. 3 S63 70. (Pubitemid 44308671)
5. Schiffman M, Castle PE. The promise of global cervical-cancer prevention. N Engl J Med 2005 353 : 2101 4. (Pubitemid 41653100)
6. NHS Cervical Screening Programme. Colposcopy and Programme Management: Guidelines for the NHS Cervical Screening Programme. Sheffield : NHSCSP Publication No 20 2004.
7. Wright TC, Cox TJ, Massad S et al. 2001 Consensus guidelines for the management of women with cervical intraepithelial neoplasia. Am J Obstet Gynecol 2004 189 : 295 304.
8. Jordan J, Arbyn M, Martin-Hirsch P et al. European guidelines for quality assurance in cervical cancer screening: recommendations for clinical management of abnormal cervical cytology, part 1. Cytopathology 2008 19 : 342 54.
9. Jordan J, Martin-Hirsch P, Arbyn M et al. European guidelines for clinical management of abnormal cervical cytology, Part 2. Cytopathology 2009 20 : 5 16.
10. Prendiville W, Walker P, Jordan J, Shafi MI. Standards for Service Provision in Colposcopy Services. London : Royal College of Obstetricians and Gynaecologists 2006.
11. Luesley DM, McCrum A, Tery PB et al. Complications of cone biopsy related to the dimensions of the cone and the influence of prior colposcopic assessment. Br J Obstet Gynaecol 1985 92 : 158 64. (Pubitemid 15162721)
12. Sommaruga P, Schwatr D, Pelte MF et al. Predictive value of loop electrosurgical excision procedure (LEEP) margin for cervical intraepithelial neoplasia (CIN) recurrence. Int J Gynecol Cancer 2005 15 (Suppl. 2 58 9.
13. Prendiville W, De Camargo M, Walker P. The use and abuse of LLETZ. CME J Gynaecol Oncol 2000 5 : 85 7.
14. Walker P, Dexeus S, De Paol G et al. International Federation for Cervical Pathology and Colposcopy Nomenclature Committee. Obstet Gynecol 2003 101 : 175 7.
15. Anderson M, Hartley T. Cervical crypt involvement by intra-epithelial neoplasia. Obstet Gynecol 1980 55 : 546 50. (Pubitemid 10068248)
16. Duncan IA. The Semm cold coagulator in the management of CIN. Clin Obstet Gynecol 1983 26 : 996 1006.
17. Duncan IA. Cold coagulation. Bailliere's Clin Obstet Gynaecol 1995 9 : 145 55.
18. Gordon HK, Duncan ID. Effective destruction of cervical intraepithelial neoplasia (CIN) at 100 C using the Semm cold coagulator. 14 years experience. Br J Obstet Gynaecol 1991 98 : 14 21.
19. Crisp WE, Asadourian L, Romberger W. Application of cryosurgery to gynecologic malignancy. Obstet Gynecol 1967 30 : 668 73.
20. Creasman WT, Weed JC Jr, Curry SL, Johnston WW, Parker RT. Efficacy of cryosurgical treatment of severe cervical intraepithelial neoplasia. Obstet Gynaecol 1973 41 : 501 6.
21. Jordan JA, Woodman CB, Mylotte MJ et al. The treatment of cervical intraepithelial neoplasia by laser vaporization. Br J Obstet Gynaecol 1985 92 : 394 8. (Pubitemid 15114222)
22. Monaghan JM. Laser vaporization and excisional techniques in the treament of cervical intraepithelial neoplasia. Bailliere's Clin Obstet Gynaecol 1995 9 : 173 87.
23. Chanen W. Electrocoagulation diathermy. Baillieres Clin Obstet Gynecol 1995 9 : 157 72.
24. Arbyn M, Kyrgiou M, Simoens C et al. Perinatal mortality and other severe adverse pregnancy outcomes associated with treatment of cervical intraepithelial neoplasia: meta-analysis. BMJ 2008 337 : a1284. doi : (Published 18 September 2008).
25. Prendiville W, Cullimore J, Norman S. Large loop excision of the transformation zone (LLETZ). A new method of management for women with cervical intra-epithelial neoplasia. Br J Obstet Gynaecol 1989 96 : 1054 60. (Pubitemid 19241567)
26. Prendiville W. LLETZ: theoretical rationale, practical aspects, clinical experience, optimizing the technique. In : Colposcopy: Management Options. Prendiville W, Ritter J, Tatti S, Twiggs L (eds). Philadelphia WB : Saunders 2003 : Ch10.
27. Prendiville W. Excision of the transformation zone. In : Lower Genital Tract Neoplasia. Maclean A, Singer A, Critchley H (eds). London : RCOG Press 2003 : pp. 179 88.
28. Prendiville W. The treatment of grade 3 cervical intraepithelial neoplasia. In : Colposcopy: Management Options. Prendiville W, Ritter J, Tatti S, Twiggs L (eds). Philadelphia WB : Saunders 2003 : Ch15.
29. Martin-Hirsch PL, Paraskevaidis E, Kitchener H. Surgery for cervical intraepithelial neoplasia. Cochrane Database Syst Rev 2002 3 : CD001318.
30. Shafi MI, Jordan JA, Singer A. The management of cervical intraepithelial neoplasia. In : The Cervix. Jordan JA, Singer A, Jones H, Shafi MI (eds). Oxford : Blackwell publications 2006 : p. 465.
31. Dobbs P, Asmussen TM, Nuns D et al. Does histological incomplete excision of CIN following LLETZ increase recurrence rates? A six-year cytological follow-up. Br J Obstet Gynaecol 2000 107 : 1298 301.
32. Flannelly G, Langham H, Jandial L et al. A study of treatment failures following large loop excision of the transformation zone for the treatment of cervical intraepithelial neoplasia. Br J Obstet Gynaecol 1997 104 : 718 32. (Pubitemid 27278356)
33. Flannelly G, Bolger B, Fawzi HD et al. Follow-up after LLETZ: could schedules be modified according to risk of recurrence. Br J Obstet Gynaecol 2001 108 : 1025 30. (Pubitemid 32971734)
34. Gardeil F, Barry-Walsh C, Prendiville W, Clinch J, Turner MJ. Persistent intraepithelial neoplasia after excision for cervical intraepithelial neoplasia grade III. Obstet Gynecol 1997 89 : 419 22. (Pubitemid 27086099)
35. Ghaem-Maghami S, Sagi S, Majeed G, Soutter WP. Incomplete excision of cervical intraepithelial neoplasia and risk of treatment failure: a meta-analysis. Lancet Oncol 2007 8 : 985 93. (Pubitemid 47629886)
36. Dimitriou E, Khalid S, Prendiville W. The Relation of Type Of Excision and Clear Histopathological Margins After LLETZ. Dublin : BSCCP presentation 2009.
37. Wright VC. Color Atlas of Colposcopy: Cervix, Vagina and Vulva. Houston : Biomedical Communications 2000.
38. Cullimore JE, Luesley DM, Rollason TP et al. A prospective study of conization of the cervix in the management of cervical intraepithelial glandular neoplasia (CIGN) - a preliminary report. Br J Obstet Gynaecol 1992 99 : 314 8.
39. Lopes A, Baynon G, Robertson G, Varas V, Monaghan JM. Short term morbidity following large loop excision of the cervical transformation zone. J Obstet Gynaecol 1994 14 : 197 9. (Pubitemid 24204148)
40. Larson G. Conisation for pre-invasive and invasive carcinoma. Acta Obstet Gynecol Scand 1983 Supplementary Issue 114 : 1 40.
41. Kyrgiou M, Koliopoulos G, Martin-Hirsch P et al. Obstetric outcomes after conservative treatment for intra-epithelial or early invasive cervical lesions: a systematic review and meta-analysis of the literature. Lancet 2006 367 : 489 98. (Pubitemid 43208905)
42. Khalid S, Dimitriou E, Prendiville W. Risk of Premature Labour After LLETZ: Does Size Matter. Dublin : Presentation BSCCP Scientific Meeting 2009.
43. Arbyn M, Paraskevaidis E, Martin-Hirsch P, Prendiville W, Dillner J. Clinical utility of HPV-DNA detection: triage of minor cervical lesions, follow-up of women treated for high-grade CIN: an update of pooled evidence. Gynecol Oncol 2005 99 (3 Suppl. 1 S7 11. (Pubitemid 41774340)
44. Kitchener HC, Walker PG, Nelson L et al. HPV testing as an adjunct to cytology in the follow up of women treated for cervical intraepithelial neoplasia. Br J Obstet Gynaecol 2008 115 : 1001 7.
45. Soutter WP, Sasieni P, Panoskaltsis T. Long-term risk of invasive cercical cancer after treatment of squamous cervical intraepithelial neoplasia. Int J Cancer 2006 118 : 2048 55.
46. Kalliala I, Anttla A, Pukkala E, Nieminen P. Risk of cervical and other cancers after treatment of cervical intraepithelial neoplasia: retrospective cohort study. BMJ (Primary Care) 2005 381 : 1183 5. (Pubitemid 41689433)
47. Strander B, Andersson-Ellström A, Milsom I, Sparén P. Long term risk of invasive cancer after treatment for cervical intraepithelial neoplasia grade 3: population based cohort study. BMJ 2007 335 : 1077. (Pubitemid 350206279)