Lean despite a genetic predisposition for obesity - Configuration of environmental factors as a chance? A case report;Schlank trotz genetischer prädisposition für adipositas - beeinflussung von umweltfaktoren als chance? Eine kasuistik
CHILD, PRESCHOOL;
ENERGY INTAKE;
FEMALE;
HUMANS;
HYPERPHAGIA;
LIFE STYLE;
OBESITY;
PEDIGREE;
POINT MUTATION;
RECEPTOR, MELANOCORTIN, TYPE 4;
SATIETY RESPONSE;
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Epidemiologie, Behandlungsstrategie und Prävention von Typ 2-Diabetes bei Kindern und Jugendlichen
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Lifestyle intervention in obese children with variations in the melanocortin 4 receptor gene
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Melanocortin-4 receptor mutations are a frequent and heterogeneous cause of morbid obesity
Vaisse C, Clement K Durand E et al. Melanocortin-4 receptor mutations are a frequent and heterogeneous cause of morbid obesity. J Clin Invest 2000; 106: 253-262
Pharmacological characterization of 40 human melanocortin-4 receptor polymorphisms with the endogenous proopiomelanocortin-derived agonists and the Agouti-related protein (AGRP) antagonist
Xiang Z, Litherland SA, Sorensen NB et al. Pharmacological characterization of 40 Human Melanocortin-4 receptor polymorphisms with the endogenous proopiomelanocortin-derived agonists and the Agouti-related protein (AGRP) antagonist. Biochemistry 2006; 45: 7277-7288
Mutations in the human melanocortin-4 receptor gene associated with severe familial obesity disrupts receptor function through multiple molecular mechanisms
Yeo GSH, Lank EJ, Farooqi IS et al. Mutations in the human melanocortin-4 receptor gene associated with severe familial obesity disrupts receptor function through multiple molecular mechanisms. Hum Molec Genet 2003; 5: 561-574