메뉴 건너뛰기




Volumn 86, Issue 2, 2009, Pages 144-156

Postnatal development in cynomolgus monkeys following prenatal exposure to natalizumab, an α4 integrin inhibitor

Author keywords

4 integrin; Cynomolgus monkey; Infants; Monoclonal antibody; Natalizumab; Postnatal evaluation; Safety assessment

Indexed keywords

NATALIZUMAB;

EID: 65549168791     PISSN: 15429733     EISSN: None     Source Type: Journal    
DOI: 10.1002/bdrb.20193     Document Type: Article
Times cited : (50)

References (33)
  • 2
    • 0000417746 scopus 로고
    • Some examples of statistical methods of research in agriculture and applied biology
    • Bartlett MS. 1937. Some examples of statistical methods of research in agriculture and applied biology. J R Stat Soc 4:137-170.
    • (1937) J R Stat Soc , vol.4 , pp. 137-170
    • Bartlett, M.S.1
  • 7
    • 0002140672 scopus 로고    scopus 로고
    • Comparative embryology
    • Hood RD, editor., New York: CRC Press
    • DeSesso JM. 1997. Comparative embryology. In: Hood RD, editor. Handbook of developmental toxicology. New York: CRC Press. p 111-173.
    • (1997) Handbook of developmental toxicology , pp. 111-173
    • DeSesso, J.M.1
  • 8
    • 0000080398 scopus 로고
    • New tables for multiple comparisons with a control
    • Dunnett CW. 1964. New tables for multiple comparisons with a control. Biometrics 20:482-491.
    • (1964) Biometrics , vol.20 , pp. 482-491
    • Dunnett, C.W.1
  • 9
    • 0024672712 scopus 로고
    • Maternal factors affecting reproduction in a breeding colony of cynomolgus macaques (macaca fascicularis)
    • Gardin JF, Jerome CP, Jayo MJ, Weaver DS. 1989. Maternal factors affecting reproduction in a breeding colony of cynomolgus macaques (Macaca fascicularis). Lab Anim Sci 39:205-212.
    • (1989) Lab Anim Sci , vol.39 , pp. 205-212
    • Gardin, J.F.1    Jerome, C.P.2    Jayo, M.J.3    Weaver, D.S.4
  • 10
    • 0028855419 scopus 로고
    • Targeted disruption of the murine vcam1 gene: Essential role of vcam-1 in chorioallantoic fusion and placentation
    • Gurtner GC, Davis V, Li H, McCoy MJ, Sharpe A, Cybulsky MT. 1995. Targeted disruption of the murine VCAM1 gene: Essential role of VCAM-1 in chorioallantoic fusion and placentation. Genes Dev 9:1-14.
    • (1995) Genes Dev , vol.9 , pp. 1-14
    • Gurtner, G.C.1    Davis, V.2    Li, H.3    McCoy, M.J.4    Sharpe, A.5    Cybulsky, M.T.6
  • 11
    • 11344265415 scopus 로고    scopus 로고
    • Effects of human and murine antisense oligonucleotide inhibitors of icam-1 on reproductive performance, fetal development, and post-natal development in mice
    • Henry SP, Denny KH, Templin MV, Yu RZ, Levin AA. 2004. Effects of human and murine antisense oligonucleotide inhibitors of ICAM-1 on reproductive performance, fetal development, and post-natal development in mice. Birth Defects Res B Dev Reprod Toxicol 71:359-367.
    • (2004) Birth Defects Res B Dev Reprod Toxicol , vol.71 , pp. 359-367
    • Henry, S.P.1    Denny, K.H.2    Templin, M.V.3    Yu, R.Z.4    Levin, A.A.5
  • 12
    • 0016420798 scopus 로고
    • Infant mortality in macaca mulatto.: Neonatal and post-neonatal mortality at the california primate research center, 1968-1972. a retrospective study
    • Hird DW, Hendrickson RV, Hendrickx AG. 1975. Infant mortality in Macaca mulatto.: Neonatal and post-neonatal mortality at the California Primate Research Center, 1968-1972. A retrospective study. J Med Primatol 4:4-22.
    • (1975) J Med Primatol , vol.4 , pp. 4-22
    • Hird, D.W.1    Hendrickson, R.V.2    Hendrickx, A.G.3
  • 13
    • 0242681945 scopus 로고
    • ICH Guideline for industry. FDA Website, Accessed July 11, 2008
    • ICH Guideline for industry. 1994. Detection of toxicity to reproduction for medicinal products. FDA Website, http://www.fda.gov/cder/Gui-dance/sSa.pdf., Accessed July 11, 2008.
    • (1994) Detection of toxicity to reproduction for medicinal products
  • 15
    • 0028978773 scopus 로고
    • Localization of alpha 4m integrin at sites of mesenchyme condensation during embryonic mouse development
    • Jaspers M, Wu RR, Van der Schueren B, Cassiman JJ. 1995. Localization of alpha 4m integrin at sites of mesenchyme condensation during embryonic mouse development. Differentiation 59:79-86.
    • (1995) Differentiation , vol.59 , pp. 79-86
    • Jaspers, M.1    Wu, R.R.2    Van Der Schueren, B.3    Cassiman, J.J.4
  • 16
    • 84943709252 scopus 로고
    • Use of ranks in one-criterion variance analysis
    • Kruskal WH, Wallis WA. 1952. Use of ranks in one-criterion variance analysis. J Am Stat Assoc 47:583-621.
    • (1952) J Am Stat Assoc , vol.47 , pp. 583-621
    • Kruskal, W.H.1    Wallis, W.A.2
  • 17
    • 65549131870 scopus 로고    scopus 로고
    • Evaluation of a surrogate antibody for safety testing. toxicology of a murine anti-cdlla antibody in mice
    • Leach W, Beyer J, Shih D, Washington C, Howell K, Zuckerman L, Clarke J. 2002. Evaluation of a surrogate antibody for safety testing. Toxicology of a murine anti-CDlla antibody in mice. Toxicologist 66:735.
    • (2002) Toxicologist , vol.66 , pp. 735
    • Leach, W.1    Beyer, J.2    Shih, D.3    Washington, C.4    Howell, K.5    Zuckerman, L.6    Clarke, J.7
  • 18
    • 2942638009 scopus 로고    scopus 로고
    • Emerging biologic therapies in inflammatory bowel disease
    • Lim WC, Hanauer SB. 2004. Emerging biologic therapies in inflammatory bowel disease. Rev Gastroenterol Disord 4:66-85.
    • (2004) Rev Gastroenterol Disord , vol.4 , pp. 66-85
    • Lim, W.C.1    Hanauer, S.B.2
  • 19
    • 0037415553 scopus 로고    scopus 로고
    • Integrin-dependence of lymphocyte entry into the splenic white pulp
    • Lo CG, Lu TT, Cyster JG. 2003. Integrin-dependence of lymphocyte entry into the splenic white pulp. J Exp Med 197:353-361.
    • (2003) J Exp Med , vol.197 , pp. 353-361
    • Lo, C.G.1    Lu, T.T.2    Cyster, J.G.3
  • 20
    • 0037135158 scopus 로고    scopus 로고
    • Integrin-rnediated long-term b cell retention in the splenic marginal zone
    • Lu TT, Cyster JG 2002. Integrin-rnediated long-term B cell retention in the splenic marginal zone. Science 297:409-412.
    • (2002) Science , vol.297 , pp. 409-412
    • Lu, T.T.1    Cyster, J.G.2
  • 21
    • 33646232502 scopus 로고    scopus 로고
    • Safety and efficacy of two dose formulations of alicaforsen enema compared with mesalazine enema for treatment of mild to moderate left-sided ulcerative colitis: A randomized, double-blind, active-controlled trial
    • Miner Jr PB, Wedel MK, Xia S, Baker BF. 2006. Safety and efficacy of two dose formulations of alicaforsen enema compared with mesalazine enema for treatment of mild to moderate left-sided ulcerative colitis: A randomized, double-blind, active-controlled trial. Aliment Pharmacol Ther 23:1403-1413.
    • (2006) Aliment Pharmacol Ther , vol.23 , pp. 1403-1413
    • Miner Jr., P.B.1    Wedel, M.K.2    Xia, S.3    Baker, B.F.4
  • 25
    • 0343853017 scopus 로고    scopus 로고
    • Integrins and reproductive physiology: Expression and modulation in fertilization, embryogenesis, and implantation
    • Sueoka K, Shiokawa S, Miyazaki T, Ku]i N, Tanaka M, Yoshimura Y. 1997. Integrins and reproductive physiology: Expression and modulation in fertilization, embryogenesis, and implantation. Fertil Steril 67: 799-811.
    • (1997) Fertil Steril , vol.67 , pp. 799-811
    • Sueoka, K.1    Shiokawa, S.2    Miyazaki, T.3    Kuji, N.4    Tanaka, M.5    Yoshimura, Y.6
  • 26
    • 0023692109 scopus 로고
    • Characterization of prenatal growth and development in the crab-eating macaque (macaca faskularis) by ultra sound
    • Tarantal AF, Hendrickx AG. 1988. Characterization of prenatal growth and development in the crab-eating macaque (Macaca faskularis) by ultra sound. Anat Rec 222:177-184.
    • (1988) Anat Rec , vol.222 , pp. 177-184
    • Tarantal, A.F.1    Hendrickx, A.G.2
  • 27
    • 65549143014 scopus 로고    scopus 로고
    • TYSABR1 (natalizumab) [prescribing information]., Inc.; available at
    • TYSABRI (natalizumab) [prescribing information]. 2008. South San Francisco, CA: Elan Pharmaceuticals, Inc.; available at www.tysabri.com.
    • (2008) Elan Pharmaceuticals
  • 28
    • 65549154548 scopus 로고    scopus 로고
    • Embryo/fetal development in cynomolgus monkeys exposed to natalizumab, an α4 integrin inhibitor
    • Wehner NG, Shopp G, Gneda S. 2009a. Embryo/Fetal development in cynomolgus monkeys exposed to natalizumab, an α4 integrin inhibitor. Birth Defects Res B Dev Reprod Toxicol 86: 117-130.
    • (2009) Birth Defects Res B Dev Reprod Toxicol , vol.86 , pp. 117-130
    • Wehner, N.G.1    Shopp, G.2    Gneda, S.3
  • 29
    • 65549090686 scopus 로고    scopus 로고
    • Effects of natalizumab, an α4 integrin inhibitor, on the development of hartley guinea pigs
    • Wehner NG, Shopp G, Rocca MS. 2009b. Effects of natalizumab, an α4 integrin inhibitor, on the development of Hartley guinea pigs. Birth Defects Res B Dev Reprod Toxicol 86:98-107.
    • (2009) Birth Defects Res B Dev Reprod Toxicol , vol.86 , pp. 98-107
    • Wehner, N.G.1    Shopp, G.2    Rocca, M.S.3
  • 30
    • 65549091168 scopus 로고    scopus 로고
    • Effects of natalizumab, an α4 integrin inhibitor, on fertility in male and female guinea pigs
    • Wehner NG, Skov S, Shopp G, Rocca MS. 2009c. Effects of natalizumab, an α4 integrin inhibitor, on fertility in male and female guinea pigs. Birth Defects Res B Dev Reprod Toxicol 86:108-116.
    • (2009) Birth Defects Res B Dev Reprod Toxicol , vol.86 , pp. 108-116
    • Wehner, N.G.1    Skov, S.2    Shopp, G.3    Rocca, M.S.4
  • 32
    • 33846804162 scopus 로고    scopus 로고
    • A randomized, double-masked, placebo-controlled study of alicaforsen, an antisense inhibitor of intercellular adhesion molecule 1, for the treatment of subjects with active crohn's disease
    • Yacyshyn B, Chey WY, Wedel MK, Yu RZ, Paul D, Chuang E. 2007. A randomized, double-masked, placebo-controlled study of alicaforsen, an antisense inhibitor of intercellular adhesion molecule 1, for the treatment of subjects with active Crohn's disease. Clin Gastro-enterol Hepatol 5:215-220.
    • (2007) Clin Gastro-enterol Hepatol , vol.5 , pp. 215-220
    • Yacyshyn, B.1    Chey, W.Y.2    Wedel, M.K.3    Yu, R.Z.4    Paul, D.5    Chuang, E.6
  • 33
    • 0028955748 scopus 로고
    • Cell adhesion events mediated by α4 integrins are essential in placental and cardiac development
    • Yang JT, Rayburn H, Hynes RO. 1995. Cell adhesion events mediated by α4 integrins are essential in placenta] and cardiac development. Development 121:549-560.
    • (1995) Development , vol.121
    • Yang, J.T.1    Rayburn, H.2    Hynes, R.O.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.