Early-stage investigations of ultrasmall superparamagnetic iron oxide-induced signal change after permanent middle cerebral artery occlusion in mice

Stroke

Volumn 40, Issue 5, 2009, Pages 1834-1841

  Desestret, Virginie ^a,b,c,d   Brisset, Jean Christophe ^a,b,c,d   Moucharrafie, Samir ^a   Devillard, Emilie ^b,c,d,e   Nataf, Serge ^a,e   Honnorat, Jérôme ^a,e   Nighoghossian, Norbert ^a,b,c,d   Berthezène, Yves ^a,b,c,d   Wiart, Marlène ^a,b,c,d  

^a UNIVERSITÉ LYON 1   (France)

^b UNIVERSITÉ DE LYON   (France)

^c CNRS   (France)

^d UNIVERSITÉ DE LYON   (France)

^e INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

GADOLINIUM; IMMUNOGLOBULIN; IRON; ULTRASMALL SUPERPARAMAGNETIC IRON OXIDE; COLORING AGENT; CONTRAST MEDIUM; DIAGNOSTIC AGENT; FERRIC ION; FERRIC OXIDE; OXIDE;

ACUTE DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN REGION; CONTROLLED STUDY; HISTOPATHOLOGY; MACROPHAGE; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PHAGOCYTE; PRIORITY JOURNAL; ANIMAL; BONE MARROW CELL; BRAIN VENTRICLE; CHEMISTRY; CORPUS CALLOSUM; DRUG EFFECT; ELECTRON SPIN RESONANCE; FLOW CYTOMETRY; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; INTRAVENOUS DRUG ADMINISTRATION; METHODOLOGY; MIDDLE CEREBRAL ARTERY; MONOCYTE; PATHOLOGY; PERIPHERAL OCCLUSIVE ARTERY DISEASE; PHAGOCYTOSIS; PHYSIOLOGY; TRANSIENT ISCHEMIC ATTACK;

ANIMALS; ARTERIAL OCCLUSIVE DISEASES; BONE MARROW CELLS; CEREBRAL VENTRICLES; COLORING AGENTS; CONTRAST MEDIA; CORPUS CALLOSUM; ELECTRON SPIN RESONANCE SPECTROSCOPY; FERRIC COMPOUNDS; FLOW CYTOMETRY; HIPPOCAMPUS; IMMUNOGLOBULINS; IMMUNOHISTOCHEMISTRY; INJECTIONS, INTRAVENOUS; IRON; ISCHEMIC ATTACK, TRANSIENT; MACROPHAGES; MAGNETIC RESONANCE IMAGING; MALE; MICE; MIDDLE CEREBRAL ARTERY; MONOCYTES; OXIDES; PHAGOCYTOSIS;

EID: 65549152740     PISSN: 00392499     EISSN: None     Source Type: Journal    
DOI: 10.1161/STROKEAHA.108.531269     Document Type: Article

References (27)

1. Muir KW, Tyrrell P, Sattar N, Warburton E. Inflammation and ischaemic stroke. Curr Opin Neurol. 2007;20:334-342.
2. Corot C, Petry KG, Trivedi R, Saleh A, Jonkmanns C, Le Bas JF, Blezer E, Rausch M, Brochet B, Foster-Gareau P, Baleriaux D, Gaillard S, Dousset V. Macrophage imaging in central nervous system and in carotid atherosclerotic plaque using ultrasmall superparamagnetic iron oxide in magnetic resonance imaging. Invest Radiol. 2004;39:619-625.
3. Jander S, Schroeter M, Saleh A. Imaging inflammation in acute brain ischemia. Stroke. 2007;38:642-645.
4. Saleh A, Schroeter M, Jonkmanns C, Hartung HP, Modder U, Jander S. In vivo MRI of brain inflammation in human ischaemic stroke. Brain. 2004;127:1670-1677.
5. Nighoghossian N, Wiart M, Cakmak S, Berthezene Y, Derex L, Cho TH, Nemoz C, Chapuis F, Tisserand GL, Pialat JB, Trouillas P, Froment JC, Hermier M. Inflammatory response after ischemic stroke: a USPIO-enhanced MRI study in patients. Stroke. 2007;38:303-307.
6. Bendszus M, Kleinschnitz C, Stoll, G. Iron-enhanced MRI in ischemic stroke: intravascular trapping versus cellular inflammation [Letter]. Stroke. 2007;38:e12.
7. Kleinschnitz C, Schutz A, Nolte I, Horn T, Frank M, Solymosi L, Stoll G, Bendszus M. In vivo detection of developing vessel occlusion in photo-thrombotic ischemic brain lesions in the rat by iron particle enhanced MRI. J Cereb Blood Flow Metab. 2005;25:1548-1555.
8. Kleinschnitz C, Bendszus M, Frank M, Solymosi L, Toyka KV, Stoll G. In vivo monitoring of macrophage infiltration in experimental ischemic brain lesions by magnetic resonance imaging. J Cereb Blood Flow Metab. 2003;23:1356-1361.
9. Petry KG, Boiziau C, Dousset V, Brochet B. Magnetic resonance imaging of human brain macrophage infiltration. Neurotherapeutics. 2007;4: 434-442.
10. Bulte JW, Frank JA. Imaging macrophage activity in the brain by using ultrasmall particles of iron oxide. AJNR Am J Neuroradiol. 2000;21: 1767-1768.
11. Engberink RD, Blezer EL, Hoff EI, van der Pol SM, van der Toorn A, Dijkhuizen RM, de Vries HE. MRI of monocyte infiltration in an animal model of neuroinflammation using SPIO-labeled monocytes or free USPIO. J Cereb Blood Flow Metab. 2007;28:841-851.
12. Rupalla K, Allegrini PR, Sauer D, Wiessner C. Time course of microglia activation and apoptosis in various brain regions after permanent focal cerebral ischemia in mice. Acta Neuropathol. 1998;96:172-178.
13. Wiart M, Davoust N, Pialat JB, Desestret V, Moucharaffie S, Cho TH, Mutin M, Langlois JB, Beuf O, Honnorat J, Nighoghossian N, Berthezene Y. MRI monitoring of neuroinflammation in mouse focal ischemia. Stroke. 2007;38:131-137.
14. Davoust N, Vuiallat C, Cavillon G, Domenget C, Hatterer E, Bernard A, Dumontel C, Jurdic P, Malcus C, Confavreux C, Belin MF, Nataf S. Bone marrow CD34+/B220+ progenitors target the inflamed brain and display in vitro differentiation potential toward microglia. FASEB J. 2006;20: 2081-2092.
15. Billotey C, Wilhelm C, Devaud M, Bacri JC, Bittoun J, Gazeau F. Cell internalization of anionic maghemite nanoparticles: quantitative effect on magnetic resonance imaging. Magn Reson Med. 2003;49:646-654.
16. Petit-Bertron AF, Pedron T, Gross U, Coppee JY, Sansonetti PJ, Cavaillon JM, Adib-Conguy M. Adherence modifies the regulation of gene expression induced by interleukin-10. Cytokine. 2005;29:1-12.
17. Schilling M, Besselmann M, Leonhard C, Mueller M, Ringelstein EB, Kiefer R. Microglial activation precedes and predominates over macro-phage infiltration in transient focal cerebral ischemia: a study in green fluorescent protein transgenic bone marrow chimeric mice. Exp Neurol. 2003;183:25-33.
18. Denes A, Vidyasagar R, Feng J, Narvainen J, Mc Coll BW, Kauppinen RA, Allan SM. Proliferating resident microglia after focal cerebral ischaemia in mice. J Cereb Blood Flow Metab. 2007;27:1941-1953.
19. von zur Muhlen C, von Elverfeldt D, Bassler N, Neudorfer I, Steitz B, Petri-Fink A, Hofmann H, Bode C, Peter K. Superparamagnetic iron oxide binding and uptake as imaged by magnetic resonance is mediated by integrin receptor Mac-1 (CD11b/CD18): implications on imaging of atherosclerotic plaques. Atherosclerosis. 2007;193:102-111.
20. Geissmann F, Jung S, Littman DR. Blood monocytes consist of two principal subsets with distinct migratory properties. Immunity. 2003;19:71-82.
21. Kida S, Steart PV, Zhang ET, Weller RO. Perivascular cells act as scavengers in the cerebral perivascular spaces and remain distinct from pericytes, microglia and macrophages. Acta Neuropathol. 1993;85: 646-652.
22. Rausch M, Baumann D, Neubacher U, Rudin M. In-vivo visualization of phagocytotic cells in rat brains after transient ischemia by USPIO. NMR Biomed. 2002;15:278-283.
23. Stroh A, Zimmer C, Werner N, Gertz K, Weir K, Kronenberg G, Steinbrink J, Mueller S, Sieland K, Dirnagl U, Nickenig G, Endres M. Tracking of systematically administrated mononuclear cells in the ische-mic brain by high-field magnetic resonance imaging. Neuroimage. 2006; 33:886-897.
24. Brisset JC, Desestret V, Marcellino S, Devillard E, Lagarde F, Nataf S, Nighoghossian N, Berthezene Y, Wiart M. T1 and T2 quantification of free USPIO and USPIO-labeled macrophages at 4.7T and 7T. 16th annual meeting of the ISMRM; Toronto, Ontario, Canada; May 3-9, 2008.
25. Durukan A, Tatlisumak T. Acute ischemic stroke: overview of major experimental rodent models, pathophysiology, and therapy of focal cerebral ischemia. Pharmacol Biochem Behav. 2007;87:179-197.
26. Saleh A, Schroeter M, Ringelstein A, Hartung HP, Siebler M, Modder U, Jander S. Iron oxide particle-enhanced MRI suggests variability of brain inflammation at early stages after ischemic stroke. Stroke. 2007;38: 2733-2737.
27. Cho TH, Nighoghossian N, Wiart M, Desestret V, Cakmak S, Berthezene Y, Derex L, Louis-Tisserand G, Honnorat J, Froment JC, Hermier M. USPIO-Enhanced MRI of neuroinflammation at the sub-acute stage of ischemic stroke: preliminary data. Cerebrovasc Dis. 2007;24:544-546.