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Volumn 46, Issue 10, 2009, Pages 2080-2089

IL-4 alters expression patterns of storage components of vascular endothelial cell-specific granules through STAT6- and SOCS-1-dependent mechanisms

Author keywords

IL 4; SOCS 1; STAT6; Vascular endothelial cell; Weibel Palade body

Indexed keywords

ANGIOPOIETIN 2; EOTAXIN 3; INTERLEUKIN 4; INTERLEUKIN 8; PADGEM PROTEIN; STAT6 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 1; VON WILLEBRAND FACTOR;

EID: 65549150532     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2009.02.015     Document Type: Article
Times cited : (10)

References (44)
  • 1
    • 0032482159 scopus 로고    scopus 로고
    • Abrogation of bronchial eosinophilic inflammation and airway hyperreactivity in signal transducers and activators of transcription (STAT)6-deficient mice
    • Akimoto T., Numata F., Tamura M., Takata Y., Higashida N., Takashi T., Takeda K., and Akira S. Abrogation of bronchial eosinophilic inflammation and airway hyperreactivity in signal transducers and activators of transcription (STAT)6-deficient mice. J. Exp. Med. 187 (1998) 1537-1542
    • (1998) J. Exp. Med. , vol.187 , pp. 1537-1542
    • Akimoto, T.1    Numata, F.2    Tamura, M.3    Takata, Y.4    Higashida, N.5    Takashi, T.6    Takeda, K.7    Akira, S.8
  • 2
    • 14044268829 scopus 로고    scopus 로고
    • Cutting edge: IL-4 induces suppressor of cytokine signaling-3 expression in B cells by a mechanism dependent on activation of p38 MAPK
    • Canfield S., Lee Y., Schroder A., and Rothman P. Cutting edge: IL-4 induces suppressor of cytokine signaling-3 expression in B cells by a mechanism dependent on activation of p38 MAPK. J. Immunol. 174 (2005) 2494-2498
    • (2005) J. Immunol. , vol.174 , pp. 2494-2498
    • Canfield, S.1    Lee, Y.2    Schroder, A.3    Rothman, P.4
  • 3
    • 4644289163 scopus 로고    scopus 로고
    • Interleukin-4 receptor signaling pathways in asthma pathogenesis
    • Chatila T.A. Interleukin-4 receptor signaling pathways in asthma pathogenesis. Trends Mol. Med. 10 (2004) 493-499
    • (2004) Trends Mol. Med. , vol.10 , pp. 493-499
    • Chatila, T.A.1
  • 5
    • 0035957410 scopus 로고    scopus 로고
    • Defect in regulated secretion of P-selectin affects leukocyte recruitment in von Willebrand factor-deficient mice
    • Denis C.V., Andre P., Saffaripour S., and Wagner D.D. Defect in regulated secretion of P-selectin affects leukocyte recruitment in von Willebrand factor-deficient mice. Proc. Natl. Acad. Sci. U.S.A. 98 (2001) 4072-4077
    • (2001) Proc. Natl. Acad. Sci. U.S.A. , vol.98 , pp. 4072-4077
    • Denis, C.V.1    Andre, P.2    Saffaripour, S.3    Wagner, D.D.4
  • 8
    • 10344262891 scopus 로고    scopus 로고
    • SOCS-1 and SOCS-3 inhibit IL-4 and IL-13 induced activation of Eotaxin-3/CCL26 gene expression in HEK293 cells
    • Hebenstreit D., Luft P., Schmiedlechner A., Duschl A., and Horejs-Hoeck J. SOCS-1 and SOCS-3 inhibit IL-4 and IL-13 induced activation of Eotaxin-3/CCL26 gene expression in HEK293 cells. Mol. Immunol. 42 (2005) 295-303
    • (2005) Mol. Immunol. , vol.42 , pp. 295-303
    • Hebenstreit, D.1    Luft, P.2    Schmiedlechner, A.3    Duschl, A.4    Horejs-Hoeck, J.5
  • 9
    • 0345447641 scopus 로고    scopus 로고
    • IL-4 and IL-13 induce SOCS-1 gene expression in A549 cells by three functional STAT6-binding motifs located upstream of the transcription initiation site
    • Hebenstreit D., Luft P., Schmiedlechner A., Regl G., Frischauf A.M., Aberger F., Duschl A., and Horejs-Hoeck J. IL-4 and IL-13 induce SOCS-1 gene expression in A549 cells by three functional STAT6-binding motifs located upstream of the transcription initiation site. J. Immunol. 171 (2003) 5901-5907
    • (2003) J. Immunol. , vol.171 , pp. 5901-5907
    • Hebenstreit, D.1    Luft, P.2    Schmiedlechner, A.3    Regl, G.4    Frischauf, A.M.5    Aberger, F.6    Duschl, A.7    Horejs-Hoeck, J.8
  • 11
    • 35548976679 scopus 로고    scopus 로고
    • Arginine-specific gingipain A from Porphyromonas gingivalis induces Weibel-Palade body exocytosis and enhanced activation of vascular endothelial cells through protease-activated receptors
    • Inomata M., Into T., Ishihara Y., Nakashima M., Noguchi T., and Matsushita K. Arginine-specific gingipain A from Porphyromonas gingivalis induces Weibel-Palade body exocytosis and enhanced activation of vascular endothelial cells through protease-activated receptors. Microbes Infect. 9 (2007) 1500-1506
    • (2007) Microbes Infect. , vol.9 , pp. 1500-1506
    • Inomata, M.1    Into, T.2    Ishihara, Y.3    Nakashima, M.4    Noguchi, T.5    Matsushita, K.6
  • 12
    • 38949178374 scopus 로고    scopus 로고
    • Regulation of MyD88-dependent signaling events by S nitrosylation retards Toll-like receptor signal transduction and initiation of acute-phase immune responses
    • Into T., Inomata M., Nakashima M., Shibata K., Hacker H., and Matsushita K. Regulation of MyD88-dependent signaling events by S nitrosylation retards Toll-like receptor signal transduction and initiation of acute-phase immune responses. Mol. Cell. Biol. 28 (2008) 1338-1347
    • (2008) Mol. Cell. Biol. , vol.28 , pp. 1338-1347
    • Into, T.1    Inomata, M.2    Nakashima, M.3    Shibata, K.4    Hacker, H.5    Matsushita, K.6
  • 13
    • 34247265992 scopus 로고    scopus 로고
    • Pathogen recognition by Toll-like receptor 2 activates Weibel-Palade body exocytosis in human aortic endothelial cells
    • Into T., Kanno Y., Dohkan J., Nakashima M., Inomata M., Shibata K., Lowenstein C.J., and Matsushita K. Pathogen recognition by Toll-like receptor 2 activates Weibel-Palade body exocytosis in human aortic endothelial cells. J. Biol. Chem. 282 (2007) 8134-8141
    • (2007) J. Biol. Chem. , vol.282 , pp. 8134-8141
    • Into, T.1    Kanno, Y.2    Dohkan, J.3    Nakashima, M.4    Inomata, M.5    Shibata, K.6    Lowenstein, C.J.7    Matsushita, K.8
  • 15
    • 0024558097 scopus 로고
    • Cloning of GMP-140, a granule membrane protein of platelets and endothelium: sequence similarity to proteins involved in cell adhesion and inflammation
    • Johnston G.I., Cook R.G., and McEver R.P. Cloning of GMP-140, a granule membrane protein of platelets and endothelium: sequence similarity to proteins involved in cell adhesion and inflammation. Cell 56 (1989) 1033-1044
    • (1989) Cell , vol.56 , pp. 1033-1044
    • Johnston, G.I.1    Cook, R.G.2    McEver, R.P.3
  • 16
    • 3442896883 scopus 로고    scopus 로고
    • Cytokine-regulated accumulation of eosinophils in inflammatory disease
    • Lampinen M., Carlson M., Hakansson L.D., and Venge P. Cytokine-regulated accumulation of eosinophils in inflammatory disease. Allergy 59 (2004) 793-805
    • (2004) Allergy , vol.59 , pp. 793-805
    • Lampinen, M.1    Carlson, M.2    Hakansson, L.D.3    Venge, P.4
  • 17
    • 33144456896 scopus 로고    scopus 로고
    • Role of interleukin-4 in atherosclerosis
    • Lee Y.W., and Hirani A.A. Role of interleukin-4 in atherosclerosis. Arch. Pharm. Res. 29 (2006) 1-15
    • (2006) Arch. Pharm. Res. , vol.29 , pp. 1-15
    • Lee, Y.W.1    Hirani, A.A.2
  • 18
    • 0033136694 scopus 로고    scopus 로고
    • IL-4 inhibits the production of TNF-α and IL-12 by STAT6-dependent and -independent mechanisms
    • Levings M.K., and Schrader J.W. IL-4 inhibits the production of TNF-α and IL-12 by STAT6-dependent and -independent mechanisms. J. Immunol. 162 (1999) 5224-5229
    • (1999) J. Immunol. , vol.162 , pp. 5224-5229
    • Levings, M.K.1    Schrader, J.W.2
  • 19
    • 0142197612 scopus 로고    scopus 로고
    • Regulation of IL4 gene expression by T cells and therapeutic perspectives
    • Li-Weber M., and Krammer P.H. Regulation of IL4 gene expression by T cells and therapeutic perspectives. Nat. Rev. Immunol. 3 (2003) 534-543
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 534-543
    • Li-Weber, M.1    Krammer, P.H.2
  • 20
    • 0033120880 scopus 로고    scopus 로고
    • Cutting edge: SOCS-1 is a potent inhibitor of IL-4 signal transduction
    • Losman J.A., Chen X.P., Hilton D., and Rothman P. Cutting edge: SOCS-1 is a potent inhibitor of IL-4 signal transduction. J. Immunol. 162 (1999) 3770-3774
    • (1999) J. Immunol. , vol.162 , pp. 3770-3774
    • Losman, J.A.1    Chen, X.P.2    Hilton, D.3    Rothman, P.4
  • 21
    • 0035523289 scopus 로고    scopus 로고
    • Role of chemokines in the pathogenesis of asthma
    • Lukacs N.W. Role of chemokines in the pathogenesis of asthma. Nat. Rev. Immunol. 1 (2001) 108-116
    • (2001) Nat. Rev. Immunol. , vol.1 , pp. 108-116
    • Lukacs, N.W.1
  • 22
    • 0024364675 scopus 로고
    • GMP-140, a platelet α-granule membrane protein, is also synthesized by vascular endothelial cells and is localized in Weibel-Palade bodies
    • McEver R.P., Beckstead J.H., Moore K.L., Marshall-Carlson L., and Bainton D.F. GMP-140, a platelet α-granule membrane protein, is also synthesized by vascular endothelial cells and is localized in Weibel-Palade bodies. J. Clin. Invest. 84 (1989) 92-99
    • (1989) J. Clin. Invest. , vol.84 , pp. 92-99
    • McEver, R.P.1    Beckstead, J.H.2    Moore, K.L.3    Marshall-Carlson, L.4    Bainton, D.F.5
  • 25
    • 42649145091 scopus 로고    scopus 로고
    • IL-13 attenuates vascular tube formation via JAK2-STAT6 pathway
    • Nishimura Y., Nitto T., Inoue T., and Node K. IL-13 attenuates vascular tube formation via JAK2-STAT6 pathway. Circ. J. 72 (2008) 469-475
    • (2008) Circ. J. , vol.72 , pp. 469-475
    • Nishimura, Y.1    Nitto, T.2    Inoue, T.3    Node, K.4
  • 26
    • 3142548720 scopus 로고    scopus 로고
    • Rapid chemokine secretion from endothelial cells originates from 2 distinct compartments
    • Øynebråten I., Bakke O., Brandtzaeg P., Johansen F.E., and Haraldsen G. Rapid chemokine secretion from endothelial cells originates from 2 distinct compartments. Blood 104 (2004) 314-320
    • (2004) Blood , vol.104 , pp. 314-320
    • Øynebråten, I.1    Bakke, O.2    Brandtzaeg, P.3    Johansen, F.E.4    Haraldsen, G.5
  • 27
    • 24644462937 scopus 로고    scopus 로고
    • Mast cells and eosinophils: a novel link between inflammation and angiogenesis in allergic diseases
    • Puxeddu I., Ribatti D., Crivellato E., and Levi-Schaffer F. Mast cells and eosinophils: a novel link between inflammation and angiogenesis in allergic diseases. J. Allergy Clin. Immunol. 116 (2005) 531-536
    • (2005) J. Allergy Clin. Immunol. , vol.116 , pp. 531-536
    • Puxeddu, I.1    Ribatti, D.2    Crivellato, E.3    Levi-Schaffer, F.4
  • 29
    • 0347955360 scopus 로고    scopus 로고
    • Regulation of NF-kappaB signaling by Pin1-dependent prolyl isomerization and ubiquitin-mediated proteolysis of p65/RelA
    • Ryo A., Suizu F., Yoshida Y., Perrem K., Liou Y.C., Wulf G., Rottapel R., Yamaoka S., and Lu K.P. Regulation of NF-kappaB signaling by Pin1-dependent prolyl isomerization and ubiquitin-mediated proteolysis of p65/RelA. Mol. Cell 12 (2003) 1413-1426
    • (2003) Mol. Cell , vol.12 , pp. 1413-1426
    • Ryo, A.1    Suizu, F.2    Yoshida, Y.3    Perrem, K.4    Liou, Y.C.5    Wulf, G.6    Rottapel, R.7    Yamaoka, S.8    Lu, K.P.9
  • 31
    • 0036467533 scopus 로고    scopus 로고
    • Cutting edge: STAT6 serves as a positive and negative regulator of gene expression in IL-4-stimulated B lymphocytes
    • Schroder A.J., Pavlidis P., Arimura A., Capece D., and Rothman P.B. Cutting edge: STAT6 serves as a positive and negative regulator of gene expression in IL-4-stimulated B lymphocytes. J. Immunol. 168 (2002) 996-1000
    • (2002) J. Immunol. , vol.168 , pp. 996-1000
    • Schroder, A.J.1    Pavlidis, P.2    Arimura, A.3    Capece, D.4    Rothman, P.B.5
  • 35
    • 0025083185 scopus 로고
    • IL-4 induces allergic-like inflammatory disease and alters T cell development in transgenic mice
    • Tepper R.I., Levinson D.A., Stanger B.Z., Campos-Torres J., Abbas A.K., and Leder P. IL-4 induces allergic-like inflammatory disease and alters T cell development in transgenic mice. Cell 62 (1990) 457-467
    • (1990) Cell , vol.62 , pp. 457-467
    • Tepper, R.I.1    Levinson, D.A.2    Stanger, B.Z.3    Campos-Torres, J.4    Abbas, A.K.5    Leder, P.6
  • 36
    • 0025305624 scopus 로고
    • IL-4 increases human endothelial cell adhesiveness for T cells but not for neutrophils
    • Thornhill M.H., Kyan-Aung U., and Haskard D.O. IL-4 increases human endothelial cell adhesiveness for T cells but not for neutrophils. J. Immunol. 144 (1990) 3060-3065
    • (1990) J. Immunol. , vol.144 , pp. 3060-3065
    • Thornhill, M.H.1    Kyan-Aung, U.2    Haskard, D.O.3
  • 37
    • 0025309259 scopus 로고
    • Characterization of the enhanced adhesion of neutrophil leukocytes to thrombin-stimulated endothelial cells
    • Toothill V.J., Van Mourik J.A., Niewenhuis H.K., Metzelaar M.J., and Pearson J.D. Characterization of the enhanced adhesion of neutrophil leukocytes to thrombin-stimulated endothelial cells. J. Immunol. 145 (1990) 283-291
    • (1990) J. Immunol. , vol.145 , pp. 283-291
    • Toothill, V.J.1    Van Mourik, J.A.2    Niewenhuis, H.K.3    Metzelaar, M.J.4    Pearson, J.D.5
  • 38
    • 0032476678 scopus 로고    scopus 로고
    • Rapid secretion of prestored interleukin 8 from Weibel-Palade bodies of microvascular endothelial cells
    • Utgaard J.O., Jahnsen F.L., Bakka A., Brandtzaeg P., and Haraldsen G. Rapid secretion of prestored interleukin 8 from Weibel-Palade bodies of microvascular endothelial cells. J. Exp. Med. 188 (1998) 1751-1756
    • (1998) J. Exp. Med. , vol.188 , pp. 1751-1756
    • Utgaard, J.O.1    Jahnsen, F.L.2    Bakka, A.3    Brandtzaeg, P.4    Haraldsen, G.5
  • 40
    • 0000534956 scopus 로고
    • New cytoplasmic components in arterial endothelia
    • Weibel E.R., and Palade G.E. New cytoplasmic components in arterial endothelia. J. Cell. Biol. 23 (1964) 101-112
    • (1964) J. Cell. Biol. , vol.23 , pp. 101-112
    • Weibel, E.R.1    Palade, G.E.2
  • 41
    • 0032968706 scopus 로고    scopus 로고
    • Immunologic basis of antigen-induced airway hyperresponsiveness
    • Wills-Karp M. Immunologic basis of antigen-induced airway hyperresponsiveness. Annu. Rev. Immunol. 17 (1999) 255-281
    • (1999) Annu. Rev. Immunol. , vol.17 , pp. 255-281
    • Wills-Karp, M.1
  • 42
    • 0032476679 scopus 로고    scopus 로고
    • Endothelial cell "memory" of inflammatory stimulation: human venular endothelial cells store interleukin 8 in Weibel-Palade bodies
    • Wolff B., Burns A.R., Middleton J., and Rot A. Endothelial cell "memory" of inflammatory stimulation: human venular endothelial cells store interleukin 8 in Weibel-Palade bodies. J. Exp. Med. 188 (1998) 1757-1762
    • (1998) J. Exp. Med. , vol.188 , pp. 1757-1762
    • Wolff, B.1    Burns, A.R.2    Middleton, J.3    Rot, A.4
  • 43
    • 0030056097 scopus 로고    scopus 로고
    • Interleukin 4 or oncostatin M induces a prolonged increase in P-selectin mRNA and protein in human endothelial cells
    • Yao L., Pan J., Setiadi H., Patel K.D., and McEver R.P. Interleukin 4 or oncostatin M induces a prolonged increase in P-selectin mRNA and protein in human endothelial cells. J. Exp. Med. 184 (1996) 81-92
    • (1996) J. Exp. Med. , vol.184 , pp. 81-92
    • Yao, L.1    Pan, J.2    Setiadi, H.3    Patel, K.D.4    McEver, R.P.5
  • 44
    • 34249660614 scopus 로고    scopus 로고
    • SOCS proteins, cytokine signalling and immune regulation
    • Yoshimura A., Naka T., and Kubo M. SOCS proteins, cytokine signalling and immune regulation. Nat. Rev. Immunol. 7 (2007) 454-465
    • (2007) Nat. Rev. Immunol. , vol.7 , pp. 454-465
    • Yoshimura, A.1    Naka, T.2    Kubo, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.