Specific expression of E-Tmod (Tmod1) in horizontal cells: Implications in neuronal cell mechanics and glaucomatous retina

MCB Molecular and Cellular Biomechanics

Volumn 6, Issue 1, 2009, Pages 71-82

  Yao, Weijuan ^a   Sung, Lanping Amy ^a  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

Erythrocyte tropomodulin; Glaucoma; Horizontal cells; Retina

Indexed keywords

A PLANES; ACTIN-CAPPING PROTEINS; CONE PHOTORECEPTORS; ERYTHROCYTE TROPOMODULIN; EYE DISEASE; GLAUCOMA; HORIZONTAL CELLS; INTRA-OCULAR PRESSURES; MECHANICAL DAMAGES; MECHANICAL STRESS; MOLECULAR RULERS; NEURODEGENERATIVE DISEASE; NEURONAL CELLS; OPTICAL NERVES; PROTOFILAMENTS; RETINA; STRESS AND STRAINS; STRESS-STRAIN ANALYSIS; STRESS-STRAIN RELATIONSHIPS; TROPOMYOSIN;

CYTOLOGY; NEURONS; OPHTHALMOLOGY; STRESS-STRAIN CURVES; STRESSES;

CELL MEMBRANES;

MUS;

TMOD1 PROTEIN, MOUSE; TROPOMODULIN;

ANIMAL; ARTICLE; BIOMECHANICS; DENDRITE; GLAUCOMA; INTRAOCULAR PRESSURE; MECHANICAL STRESS; METABOLISM; MOUSE; MOUSE MUTANT; NERVE FIBER; OPTIC DISK; PATHOLOGY; PATHOPHYSIOLOGY; PHOTORECEPTOR CELL; PHYSIOLOGY; RETINA BIPOLAR GANGLION CELL; RETINA GANGLION CELL; RETINA HORIZONTAL NERVE CELL;

ANIMALS; AXONS; BIOMECHANICS; DENDRITES; GLAUCOMA; INTRAOCULAR PRESSURE; MICE; MICE, KNOCKOUT; OPTIC DISK; PHOTORECEPTOR CELLS, VERTEBRATE; RETINAL BIPOLAR CELLS; RETINAL GANGLION CELLS; RETINAL HORIZONTAL CELLS; STRESS, MECHANICAL; TROPOMODULIN;

EID: 65549124115     PISSN: 15565297     EISSN: 15565300     Source Type: Journal    
DOI: None     Document Type: Article

References (60)

1. Agar, A., Li, S., Agarwal, N., Coroneo, M.T., Hill, M.A. (2006) Retinal ganglion cell line apoptosis induced by hydrostatic pressure. Brain Res. 1086, 191-200.
2. Alamouti, B., Funk, J. (2003) Retinal thickness decreases with age: an OCT study. Br. J. Ophthalmol. 87, 899-901.
3. Almenar-Queralt, A., Lee, A., Conley, C.A., Ribas de Pouplana, L., Fowler, V.M. (1999) Identification of a novel tropomodulin isoform, skeletal tropomodulin, that caps actin filament pointed ends in fast skeletal muscle. J. Biol. Chem. 274, 28466-28475.
4. Candiello, J., Balasubramani, M., Schreiber, E.M., Cole, G.J., Mayer, U., Halfter, W., Lin, H. (2007) Biomechanical properties of native basement membranes. FEBS J. 274, 2897-2908
5. Chu, X., Chen, J., Reedy, M.C., Vera, C., Sung, K.L., Sung, L.A. (2003) E-Tmod capping of actin filaments at the slow-growing end is required to establish mouse embryonic circulation. Am. J. Physiol. Heart Circ. Physiol. 284, H1827-1838.
6. Chu, X., Thompson, D., Yee, L.J., Sung, L.A. (2000) Genomic organization of mouse and human erythrocyte tropomodulin genes encoding the pointed end capping protein for the actin filaments. Gene 256, 271-281.
7. Chun, M., Kim, I., Ju, W., Kim, K., Lee, M., Joo, C., Chung, J. (1999) Horizontal cells of the rat retina are resistant to degenerative processes induced by ischemia-reperfusion. Neurosci. Lett. 260, 125-128.
8. Clark, J.H. (1932) A method for measuring elasticity in vivo and results obtained on the eyeball at different intraocular pressures. Am. J. Physiol. 101, 474-481.
9. Danesh-Meyer, H.V., Gaskin, B.J., Tayusundera, T., Donaldson,M., Gamble, G.D. (2006) Comparison of disc damage likelihood scale, cup to disc ratio, and Heidelberg retina tomograph in the diagnosis of glaucoma. Br. J. Ophthalmol. 90, 437-441.
10. Edwards, M.E, Good, T.A. (2001) Use of a mathematical model to estimate stress and strain during elevated pressure induced lamina cribrosa deformation. Curr. Eye Res. 23, 215-225.
11. Fowler, V.M. (1987) Identification and purification of a novel Mr 43,000 tropomyosinbinding protein from human erythrocyte membranes. J. Biol. Chem. 262, 12792-12800.
12. Fowler, V.M., Sussmann M.A., Miller P.G., Flucher, B.E., Daniels, M.P. (1993) Tropomodulin is associated with the free (pointed) ends of the thin filaments in rat skeletal muscle. J. Cell Biol. 120, 411-420.
13. Fritz-Six, K.L., Cox, P.R., Fischer, R.S., Xu, B., Gregorio, C.C., Zoghbi, H.Y., Fowler, V.M. (2003) Aberrant myofibril assembly in tropomodulin1 null mice leads to aborted heart development and embryonic lethality. J. Cell Biol. 163, 1033-1044.
14. Friedenwald, J.S. (1937) Contribution to the theory and practice of tonometry. Am. J. Ophthalmol. 20, 985-1024.
15. Fu, X., Sun, H., Klein, W.H., Mu, X. (2006) β-catenin is essential for lamination but not neurogenesis in mouse retinal development. Dev. Biol. 299, 424-437.
16. Fung, Y.C. (1993) Biomechanics: mechanical properties of living tissues. Second Edition. Springer-Verlag, New York.
17. Gregorio, C.C., Weber, A., Bondad, M., Pennise, C.R., Fowler, V.M. (1995) Requirement of pointed-end capping by tropomodulin to maintain actin filament length in embryonic chick cardiac myocytes. Nature 377, 83-86.
18. Gupta, N., Yücel, Y.H. (2007) Glaucoma as a neurodegenerative disease. Curr. Opin. Ophthalmol. 18,110-114.
19. Heredia, A., Bui, C.C., Suter, U., Young, P., Schäffer, T.E. (2007) AFM combines functional and morphological analysis of peripheral myelinated and demyelinated nerve fibers. NeuroImage 37, 1218-1226.
20. Higdon, A., Ohlsen, E.H., Stiles, W.B., Weese, J.A., Riley, W.F. (1985) Mechanics of Materials, Fourth Edition, John Wiley & Sons.
21. Hogan, B., Constantini, F., Lacy, E. (1986) Manipulating themouse, a laboratory manual. Cold Spring Harbor. NY: Cold Spring Harbor Laboratory, 375.
22. Isayama, T., Goodman, S.R., Zagon, I.S. (1991). Spectrin isoforms in the mammalian retina. J. Neurosci. 11, 3531-3538.
23. Jakobs, T.C., Libby, R.T., Ben, Y., John, S.W., Masland, R.H. (2005) Retinal ganglion cell degeneration is topological but not cell type specific in DBA/2J mice. J. Cell Biol. 171, 313-325.
24. Janssen, P., Naskar, R., Moore, S., Thanos, S., Thiel, H.J. (1996) Evidence for glaucoma-induced horizontal cell alterations in the human retina. Ger. J. Ophthalmol. 5, 378-385.
25. Jonas, J.B., Hayreh, S.S. (1999) Localised retinal nerve fibre layer defects in chronic experimental high pressure glaucoma in rhesus monkeys. Br. J. Ophthalmol. 83, 1291-1295.
26. Jonas, J.B., Mardin, C.Y. Schlörzer-Schrehardr, U., Naumann, G.O.H. (1991) Morphometry of the human lamina cribrosa surface. Invest. Ophthalmol. Vis. Sci., 32, 401-405.
27. Jones, I.L., Warner, M., Stevens, J.D. (1992) Mathematical modeling of the elastic properties of retina: A determination of Young's modulus. Eye 6, 556-559.
28. Ju, W.k., Liu, Q., Kim, K.Y., Crowston, J.G., Kindsy, J.D., Agarwal, N., Ellisman, M.H., Perkins, G.A., Weinreb, R.N. (2007) Elevated hydrostatic pressure triggers mitochondrial fission and decreases cellular ATP in differentiated RGC-5 cells. Invest Ophthalmol Vis Sci 48, 2145-2151.
29. Kendell, K.R., Quigley, H.A., Kerrigan, L.A., Pease, M.E., Quigley, E.N. (1995) Primary open-angle glaucoma is not associated with photoreceptor loss. Invest. Ophthalmol. Vis. Sci. 36, 200-205.
30. Liu, J.H.K. (1998). Circadian rhythm of intraocular pressure. J. Glaucoma 7, 141-147.
31. Liu, J.H.K., Zhang, X., Kripke, D.F., Weinreb, R.N. (2003) Twenty-four-hour intraocular pressure pattern associated with early glaucomatous changes. Invest. Ophthalmol. Vis. Sci. 44, 1586-1590.
32. Liu, Q., Ju, W.K., Crowston, J.G., Xie, F., Perry, G., Smith, M.A., Lindsey, J.D., Weinreb, R.N. (2007) Oxidative stress is an early event in hydrostatic pressure induced retinal ganglion cell damage. Invest. Ophthalmol. Vis. Sci. 48, 4580-4589.
33. Morgan, J.E., Jeffery, G., Foss, A.J.E. (1998) Axon deviation in the human lamina cribrosa. Br. J. Ophthalmol. 82, 680-683.
34. Oyster, C.W. (1999) The human eye: structure and function. 1stEdition, Sinauer, Sunderland, Massachusetts, pp. 595-631.
35. Pierscoinek, B.K., Asejczyk-Widlicka, M., Schachar, R.A. (2007) The effect of changing intraocular pressure on the corneal and scleral curvatures in the fresh porcine eye. Br. J. Ophthalmol. 91, 801-803.
36. Quigley, H.A.,Green, W.R. (1979). The histology of human glaucoma cupping and optic nerve damage: clinicopathologic correlation in 21 eyes. Ophthalmology 10, 1803-1827.
37. Raven, M.A., Stagg, S.B., Nassar, H., Reese, B.E. (2005) Developmental improvement in the regularity and packing of mouse horizontal cells: implications for mechanisms underlying mosaic pattern formation. Vis. Neurosci. 22, 569-573.
38. Sano, Y., Furuta, A., Setsuie, R., Kikuchi, H., Wang, Y., Sakurai, M., Kwon, J., Noda, M., Wada, K. (2006) Photoreceptor Cell Apoptosis in the Retinal Degeneration of Uchl3-Deficient Mice. Am. J. Pathol. 169, 132-141.
39. Schevzov, G., Gunning, P., Jeffrey, P.L., Temm-Grove, C., Helfman, D.M., Lin, J.J., Weinberger, R.P., (1997) Tropomyosin localization reveals distinct population of microfilaments in neurites and growth cones. Mol. Cell Neurosci. 8, 439-454.
40. Sigal, I.A., Flanagan, J.G., Tertinegg, I., Ethier, C.R. (2004) Finite element modeling of optic nerve head biomechanics. Invest Ophthalmol. Vis. Sci. 45, 4378-4387.
41. Sigal, I.A., Flanagan, J.G., Tertinegg, I., Ethier, C.R. (2007) Predicted extension, compression and shearing of optic nerve head tissues. Exp. Eye Res. 85, 312-322.
42. Silver, D.M., Geyer, O. (2000) Pressure-volume relation for the living human eye. Curr. Eye Res. 20, 115-120.
43. Sung, L.A., Fowler, V.M., Lambert, K., Sussman, M.A., Karr, D., Chien, S. (1992) Molecular cloning and characterization of human fetal liver tropomodulin.A tropomyosinbinding protein. J. Biol. Chem. 267, 2616-2621.
44. Sung, L.A., Gao, K.M., Yee, L.J., Temm-Grove, C.J., Helfman, D.M., Lin, J.J., Mehrpouryan, M. (2000) Tropomyosin isoform 5b is expressed in human erythrocytes: implications of tropomodulin-TM5 or tropomodulin-TM5b complexes in the protofilament and hexagonal organization of membrane skeletons. Blood 95, 1473-1480.
45. Sung, L.A., Lin, J.J. (1994) Erythrocyte tropomodulin binds to the N-terminus of hTM5, a tropomyosin isoform encoded by the gamma-tropomyosin gene. Biochemical and biophysical research communications 201, 627-634.
46. Sung, LA, Vera, C. (2003) Protofilament and hexagon: a three-dimensional mechanical model for the junctional complex in the erythrocyte membrane skeleton. Ann. Biomed. Eng. 31, 1314-1326.
47. Sussman, M.A., Sakhi, S., Tocco, G., Najm, I., Baudry, M., Kedes, L., Schreiber, S.S. (1994) Neural tropomodulin: developmental expression and effect of seizure activity. Brain Res. Dev. Brain Res. 80, 45-53.
48. Tan, J.C.H., Kalapesi F.B., Coroneo, M.T. (2006) Mechanosensitivity and the eye: cells coping with the pressure. Br. J. Ophthalmol. 90, 383-388.
49. Vaughan, D.K., Lasater, E.M. (1990) Distribution of F-actin in bipolar and horizontal cells of bass retinas. Am. J. Physiol. Cell Physiol. 259, C205-C214.
50. Vera, C., Lao, J., Hamelberg, D., Sung, L.A. (2005) Mapping the tropomyosin isoform 5 binding site on human erythrocyte tropomodulin: further insights into E-Tmod/TM5 interaction. Arch. Biochem. Biophys. 444, 130-138.
51. Vera, C., Sood, A., Gao, K.M., Yee, L.J., Lin, J.J., Sung, L.A. (2000) Tropomodulin-Binding Site Mapped to Residues 7 C14 at the N-Terminal Heptad Repeats of Tropomyosin Isoform 5. Archives of Biochemistry and Biophysics 378, 16-24.
52. Vrhovski, B., Schevzov, G., Dingle, S., Lessard, J.L., Gunning, P., Weinberger, R.P. (2003) Tropomyosin isoforms from the gamma gene differing at the C-terminus are spatially and developmentally regulated in the brain. J. Neurosci. Res. 72, 373-383.
53. Weber, A., Pennise, C.R., Babcock, G.G., Fowler, V.M. (1994) Tropomodulin caps the pointed ends of actin filaments. J. Cell Biol. 127, 1627-1635.
54. Weber, A., Pennise, C.R., Fowler, V.M. (1999) Tropomodulin increases the critical concentration of barbed end-capped actin filaments by converting ADP. P(i)-actin to ADP-actin at all pointed filament ends. J. Biol. Chem. 274, 34637-34645.
55. Woo, M.K., Fowler, V.M. (1994). Identification and characterization of tropomodulin and tropomyosin in the adult rat lens. J. Cell Sci. 107, 1359-1367.
56. Yang, X., Gao, F., Wu, S.M. (1999) Modulation of horizontal cell function by GABAA and GABAC receptors in dark- and light-adapted tiger salamander retina. Vis. Neurosci. 16, 967-979.
57. Yao, W., Nathanson, J., Lian, I., Gage, F.H., Sung, L.A. (2007) Mouse erythrocyte tropomodulin in the brain reported by lacZ knocked-in downstream from the E1 promoter. Gene Expr. Patterns 8, 36-46.
58. Zhou, Y., Wang, G., Ding, H., Jiao, Y. (2005) Finite Element Modeling and Biomechanical Analysis of Eyeball and Extraocular Muscles. Proc. 2005 IEEE. 4978-4981.
59. Zhu, Q., Vera, C., Asaro, R.J., Sche, P., Sung, L.A. (2007) A hybrid model for erythrocyte membrane: a single unit of protein network coupled with lipid bilayer. Biophysical Journal 93, 386-400.
60. Zinn, W., Solomon, H. (1965) Eye care, eye glasses and contact lenses. City: Lifetime Books, 10.