Avoiding unintended toxicity

Science

Volumn 324, Issue 5927, 2009, Pages 603-604

  Golde, Todd E ^a   Kukar, Thomas L ^a  

^a MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-42]; AMYLOID PRECURSOR PROTEIN; ANTERIOR PHARYNX DEFECTIVE 1 PROTEIN; BETA SECRETASE; DEXAMETHASONE; GAMMA SECRETASE; GAMMA SECRETASE INHIBITOR; ISOPROTEIN; NICASTRIN; NOTCH RECEPTOR; PRESENILIN 1; PRESENILIN 2; PROTEINASE; TARENFLURBIL; APH1A PROTEIN, MOUSE; APH1B PROTEIN, MOUSE; APH1C PROTEIN, MOUSE; PROTEIN SUBUNIT; PROTEINASE INHIBITOR; SECRETASE;

BRAIN; DISEASE; PATHOLOGY; PROTEIN;

ALZHEIMER DISEASE; AMINO TERMINAL SEQUENCE; BLOOD BRAIN BARRIER; CARBOXY TERMINAL SEQUENCE; COMPLEX FORMATION; DRUG ANTAGONISM; DRUG BINDING; ENZYME INHIBITION; HUMAN; MEMBRANE DAMAGE; MOLECULAR CLONING; NEOPLASM; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN SYNTHESIS; SHORT SURVEY; SIGNAL TRANSDUCTION; ANIMAL; CHEMISTRY; DRUG EFFECT; METABOLISM; MOUSE; NOTE;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ENDOPEPTIDASES; HUMANS; MICE; PROTEASE INHIBITORS; PROTEIN SUBUNITS; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION;

EID: 65549117881     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1174267     Document Type: Short Survey

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