-
1
-
-
0037603589
-
Mutations in PCSK9 cause autosomal dominant hypercholesterolemia
-
Abifadel M, Varret M, Rabes JP, Allard D, Ouguerram K, Devillers M, Cruaud C, Benjannet S, Wickham L, Erlich D, Derre A, Villeger L, Farnier M, Beucler I, Bruckert E, Chambaz J, Chanu B, Lecerf JM, Luc G, Moulin P, Weissenbach J, Prat A, Krempf M, Junien C, Seidah NG, Boileau C. Mutations in PCSK9 cause autosomal dominant hypercholesterolemia. Nat Genet 2003;34:154-156.
-
(2003)
Nat Genet
, vol.34
, pp. 154-156
-
-
Abifadel, M.1
Varret, M.2
Rabes, J.P.3
Allard, D.4
Ouguerram, K.5
Devillers, M.6
Cruaud, C.7
Benjannet, S.8
Wickham, L.9
Erlich, D.10
Derre, A.11
Villeger, L.12
Farnier, M.13
Beucler, I.14
Bruckert, E.15
Chambaz, J.16
Chanu, B.17
Lecerf, J.M.18
Luc, G.19
Moulin, P.20
Weissenbach, J.21
Prat, A.22
Krempf, M.23
Junien, C.24
Seidah, N.G.25
Boileau, C.26
more..
-
2
-
-
33846679386
-
Molecular biology of PCSK9: Its role in LDL metabolism
-
Horton JD, Cohen JC, Hobbs HH. Molecular biology of PCSK9: its role in LDL metabolism. Trends Biochem Sci. 2007;32:71-77.
-
(2007)
Trends Biochem Sci
, vol.32
, pp. 71-77
-
-
Horton, J.D.1
Cohen, J.C.2
Hobbs, H.H.3
-
3
-
-
34547108600
-
Binding of PCSK9 to EGF-A repeat of LDL receptor decreases receptor recycling and increases degradation
-
Zhang DW, Lagace TA, Garuti R, Zhao Z, McDonald M, Horton JD, Cohen JC, Hobbs HH. Binding of PCSK9 to EGF-A repeat of LDL receptor decreases receptor recycling and increases degradation. J Biol Chem. 2007;282:18602-18612.
-
(2007)
J Biol Chem
, vol.282
, pp. 18602-18612
-
-
Zhang, D.W.1
Lagace, T.A.2
Garuti, R.3
Zhao, Z.4
McDonald, M.5
Horton, J.D.6
Cohen, J.C.7
Hobbs, H.H.8
-
4
-
-
33645103550
-
Sequence variations in PCSK9, low LDL, and protection against coronary heart disease
-
Cohen JC, Boerwinkle E, Mosley TH Jr, Hobbs HH. Sequence variations in PCSK9, low LDL, and protection against coronary heart disease. N Engl J Med. 2006;354:1264-1272.
-
(2006)
N Engl J Med
, vol.354
, pp. 1264-1272
-
-
Cohen, J.C.1
Boerwinkle, E.2
Mosley Jr, T.H.3
Hobbs, H.H.4
-
5
-
-
13944265645
-
Low LDL cholesterol in individuals of African descent resulting from frequent nonsense mutations in PCSK9
-
Cohen J, Pertsemlidis A, Kotowski IK, Graham R, Garcia CK, Hobbs HH. Low LDL cholesterol in individuals of African descent resulting from frequent nonsense mutations in PCSK9. Nat Genet. 2005;37: 161-165.
-
(2005)
Nat Genet
, vol.37
, pp. 161-165
-
-
Cohen, J.1
Pertsemlidis, A.2
Kotowski, I.K.3
Graham, R.4
Garcia, C.K.5
Hobbs, H.H.6
-
6
-
-
34447520136
-
Fasting compared with nonfasting triglycerides and risk of cardiovascular events in women
-
Bansal S, Buring JE, Rifai N, Mora S, Sacks FM, Ridker PM. Fasting compared with nonfasting triglycerides and risk of cardiovascular events in women. JAMA. 2007;298:309-316.
-
(2007)
JAMA
, vol.298
, pp. 309-316
-
-
Bansal, S.1
Buring, J.E.2
Rifai, N.3
Mora, S.4
Sacks, F.M.5
Ridker, P.M.6
-
7
-
-
34447511196
-
Nonfasting triglycerides and risk of myocardial infarction, ischemic heart disease, and death in men and women
-
Nordestgaard BG, Benn M, Schnoh P, Tybjaerg-Hansen A. Nonfasting triglycerides and risk of myocardial infarction, ischemic heart disease, and death in men and women. JAMA. 2007;298:299-308.
-
(2007)
JAMA
, vol.298
, pp. 299-308
-
-
Nordestgaard, B.G.1
Benn, M.2
Schnoh, P.3
Tybjaerg-Hansen, A.4
-
8
-
-
17244377696
-
Decreased plasma cholesterol and hypersensitivity to statins in mice lacking Pcsk9
-
Rashid S, Curtis DE, Garuti R, Anderson NN, Bashmakov Y, Ho YK, Hammer RE, Moon YA, Horton JD. Decreased plasma cholesterol and hypersensitivity to statins in mice lacking Pcsk9. Proc Natl Acad Sci U S A. 2005;102:5374-5379.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 5374-5379
-
-
Rashid, S.1
Curtis, D.E.2
Garuti, R.3
Anderson, N.N.4
Bashmakov, Y.5
Ho, Y.K.6
Hammer, R.E.7
Moon, Y.A.8
Horton, J.D.9
-
9
-
-
35348955284
-
Development and physiological regulation of intestinal lipid absorption. II. Dietary lipid absorption, complex lipid synthesis, and the intracellular packaging and secretion of chylomicrons
-
Mansbach CM, Gorelick F. Development and physiological regulation of intestinal lipid absorption. II. Dietary lipid absorption, complex lipid synthesis, and the intracellular packaging and secretion of chylomicrons. Am J Physiol Gastrointest Liver Physiol. 2007;293:G645-G650.
-
(2007)
Am J Physiol Gastrointest Liver Physiol
, vol.293
-
-
Mansbach, C.M.1
Gorelick, F.2
-
10
-
-
0025149320
-
Fat feeding increases size, but not number, of chylomicrons produced by small intestine
-
Hayashi H, Fujimoto K, Cardelli JA, Nutting DF, Bergstedt S, Tso P. Fat feeding increases size, but not number, of chylomicrons produced by small intestine. Am J Physiol. 1990;259:G709-G719.
-
(1990)
Am J Physiol
, vol.259
-
-
Hayashi, H.1
Fujimoto, K.2
Cardelli, J.A.3
Nutting, D.F.4
Bergstedt, S.5
Tso, P.6
-
11
-
-
15644373479
-
A single copy of apolipoprotein B-48 is present on the human chylomicron remnant
-
Phillips ML, Pullinger C, Kroes I, Kroes J, Hardman DA, Chen G, Curtiss LK, Gutierrez MM, Kane JP, Schumaker VN. A single copy of apolipoprotein B-48 is present on the human chylomicron remnant. J Lipid Res. 1997;38:1170-1177.
-
(1997)
J Lipid Res
, vol.38
, pp. 1170-1177
-
-
Phillips, M.L.1
Pullinger, C.2
Kroes, I.3
Kroes, J.4
Hardman, D.A.5
Chen, G.6
Curtiss, L.K.7
Gutierrez, M.M.8
Kane, J.P.9
Schumaker, V.N.10
-
12
-
-
38349186574
-
Why does the gut choose apolipoprotein B48 but not B100 for chylomicron formation?
-
Lo CM, Nordskog BK, Nauli AM, Zheng S, Vonlehmden SB, Yang Q, Lee D, Swift LL, Davidson NO, Tso P. Why does the gut choose apolipoprotein B48 but not B100 for chylomicron formation? Am J Physiol Gastrointest Liver Physiol. 2008;294:G344-G352.
-
(2008)
Am J Physiol Gastrointest Liver Physiol
, vol.294
-
-
Lo, C.M.1
Nordskog, B.K.2
Nauli, A.M.3
Zheng, S.4
Vonlehmden, S.B.5
Yang, Q.6
Lee, D.7
Swift, L.L.8
Davidson, N.O.9
Tso, P.10
-
13
-
-
0034001470
-
Relative roles of LDLr and LRP in the metabolism of chylomicron remnants in genetically manipulated mice
-
Martins IJ, Hone E, Chi C, Seydel U, Martins RN, Redgrave TG. Relative roles of LDLr and LRP in the metabolism of chylomicron remnants in genetically manipulated mice. J Lipid Res. 2000;41:205-213.
-
(2000)
J Lipid Res
, vol.41
, pp. 205-213
-
-
Martins, I.J.1
Hone, E.2
Chi, C.3
Seydel, U.4
Martins, R.N.5
Redgrave, T.G.6
-
14
-
-
0035023285
-
-
Recommendations for cryopreservation of cells tumor tissues to be used for molecular analyses
-
[Recommendations for cryopreservation of cells tumor tissues to be used for molecular analyses]. Ann Pathol. 2001;21:184-201.
-
(2001)
Ann Pathol
, vol.21
, pp. 184-201
-
-
-
16
-
-
67749146985
-
-
Deleted in proof
-
Deleted in proof.
-
-
-
-
17
-
-
0024420536
-
Immunohistochemical localization of low density lipoprotein receptors in adrenal gland, liver, and intestine
-
Fong LG, Bonney E, Kosek JC, Cooper AD. Immunohistochemical localization of low density lipoprotein receptors in adrenal gland, liver, and intestine. J Clin Invest. 1989;84:847- 856.
-
(1989)
J Clin Invest
, vol.84
, pp. 847-856
-
-
Fong, L.G.1
Bonney, E.2
Kosek, J.C.3
Cooper, A.D.4
-
18
-
-
3943060193
-
Statins upregulate PCSK9, the gene encoding the proprotein convertase neural apoptosis-regulated convertase-1 implicated in familial hypercholesterolemia
-
Dubuc G, Chamberland A, Wassef H, Davignon J, Seidah NG, Bernier L, Prat A. Statins upregulate PCSK9, the gene encoding the proprotein convertase neural apoptosis-regulated convertase-1 implicated in familial hypercholesterolemia. Arterioscler Thomb Vasc Biol. 2004;24: 1454-1459.
-
(2004)
Arterioscler Thomb Vasc Biol
, vol.24
, pp. 1454-1459
-
-
Dubuc, G.1
Chamberland, A.2
Wassef, H.3
Davignon, J.4
Seidah, N.G.5
Bernier, L.6
Prat, A.7
-
19
-
-
44349177547
-
Dual mechanisms for the fibrate-mediated repression of proprotein convertase subtilisin/kexin type 9
-
Kourimate S, Le May C, Langhi C, Jarnoux AL, Ouguerram K, Zair Y, Nguyen P, Krempf M, Cariou B, Costet P. Dual mechanisms for the fibrate-mediated repression of proprotein convertase subtilisin/kexin type 9. J Biol Chem. 2008;283:9666-9673.
-
(2008)
J Biol Chem
, vol.283
, pp. 9666-9673
-
-
Kourimate, S.1
Le May, C.2
Langhi, C.3
Jarnoux, A.L.4
Ouguerram, K.5
Zair, Y.6
Nguyen, P.7
Krempf, M.8
Cariou, B.9
Costet, P.10
-
20
-
-
40349110828
-
Activation of the farnesoid X receptor represses pcsk9 expression in human hepatocytes
-
Langhi C, Le May C, Kourimate S, Caron S, Staels B, Krempf M, Costet P, Cariou B. Activation of the farnesoid X receptor represses pcsk9 expression in human hepatocytes. FEBS Lett. 2008;19:949-955.
-
(2008)
FEBS Lett
, vol.19
, pp. 949-955
-
-
Langhi, C.1
Le May, C.2
Kourimate, S.3
Caron, S.4
Staels, B.5
Krempf, M.6
Costet, P.7
Cariou, B.8
-
21
-
-
34547939912
-
Mesenteric lymph: The bridge to future management of critical illness
-
Fanous MY, Phillips AJ, Windsor JA. Mesenteric lymph: the bridge to future management of critical illness. JOP. 2007;8:374 -399.
-
(2007)
JOP
, vol.8
, pp. 374-399
-
-
Fanous, M.Y.1
Phillips, A.J.2
Windsor, J.A.3
-
22
-
-
34147136507
-
Antisense inhibition of proprotein convertase subtilisin/kexin type 9 reduces serum LDL in hyperlipidemic mice
-
Graham MJ, Lemonidis KM, Whipple CP, Subramaniam A, Monia BP, Crooke ST, Crooke RM. Antisense inhibition of proprotein convertase subtilisin/kexin type 9 reduces serum LDL in hyperlipidemic mice. J Lipid Res. 2007;48:763-767.
-
(2007)
J Lipid Res
, vol.48
, pp. 763-767
-
-
Graham, M.J.1
Lemonidis, K.M.2
Whipple, C.P.3
Subramaniam, A.4
Monia, B.P.5
Crooke, S.T.6
Crooke, R.M.7
-
23
-
-
0027172292
-
Apoli-poprotein B mRNA editing in 12 different mammalian species: Hepatic expression is reflected in low concentrations of apoB-containing plasma lipoproteins
-
Greeve J, Altkemper I, Dieterich JH, Greten H, Windler E. Apoli-poprotein B mRNA editing in 12 different mammalian species: hepatic expression is reflected in low concentrations of apoB-containing plasma lipoproteins. J Lipid Res. 1993;34:1367-1383.
-
(1993)
J Lipid Res
, vol.34
, pp. 1367-1383
-
-
Greeve, J.1
Altkemper, I.2
Dieterich, J.H.3
Greten, H.4
Windler, E.5
-
24
-
-
0034003980
-
The role of the LDL receptor in apolipoprotein B secretion
-
Twisk J, Gillian-Daniel DL, Tebon A, Wang L, Barrett PH, Attie AD. The role of the LDL receptor in apolipoprotein B secretion. J Clin Invest. 2000;105:521-532.
-
(2000)
J Clin Invest
, vol.105
, pp. 521-532
-
-
Twisk, J.1
Gillian-Daniel, D.L.2
Tebon, A.3
Wang, L.4
Barrett, P.H.5
Attie, A.D.6
-
25
-
-
0029808272
-
Role of the low density lipoprotein (LDL) receptor pathway in the metabolism of chylomicron remnants. A quantitative study in knockout mice lacking the LDL receptor, apolipoprotein E, or both
-
Ishibashi S, Perrey S, Chen Z, Osuga J, Shimada M, Ohashi K, Harada K, Yazaki Y, Yamada N. Role of the low density lipoprotein (LDL) receptor pathway in the metabolism of chylomicron remnants. A quantitative study in knockout mice lacking the LDL receptor, apolipoprotein E, or both. J Biol Chem. 1996;271:22422-22427.
-
(1996)
J Biol Chem
, vol.271
, pp. 22422-22427
-
-
Ishibashi, S.1
Perrey, S.2
Chen, Z.3
Osuga, J.4
Shimada, M.5
Ohashi, K.6
Harada, K.7
Yazaki, Y.8
Yamada, N.9
-
26
-
-
0842281358
-
Lack of evidence for reduced plasma apo B48 catabolism in patients with heterozygous familial hypercholesterolemia carrying the same null LDL receptor gene mutation
-
Tremblay AJ, Lamarche B, Ruel I, Hogue JC, Bergeron J, Gagne C, Couture P. Lack of evidence for reduced plasma apo B48 catabolism in patients with heterozygous familial hypercholesterolemia carrying the same null LDL receptor gene mutation. Atherosclerosis. 2004;172:367-373.
-
(2004)
Atherosclerosis
, vol.172
, pp. 367-373
-
-
Tremblay, A.J.1
Lamarche, B.2
Ruel, I.3
Hogue, J.C.4
Bergeron, J.5
Gagne, C.6
Couture, P.7
|