Infiltrating cells and IFNγ production in the injected eye after uniocular anterior chamber inoculation of HSV-1

Investigative Ophthalmology and Visual Science

Volumn 50, Issue 5, 2009, Pages 2269-2275

  Cathcart, Heather M ^a   Fields, Mark A ^a   Zheng, Mei ^a   Marshall, Brendan ^a   Atherton, Sally S ^a  

^a MEDICAL COLLEGE OF GEORGIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA2 INTEGRIN; ANTIGEN F4; CD11B ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; CELL ANTIGEN; GAMMA INTERFERON; GLYCOPROTEIN P 15095; UNCLASSIFIED DRUG; BIOLOGICAL MARKER; DIFFERENTIATION ANTIGEN; LEUKOCYTE ANTIGEN; MONOCYTE MACROPHAGE DIFFERENTIATION ANTIGEN; MONOCYTE-MACROPHAGE DIFFERENTIATION ANTIGEN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTERIOR EYE CHAMBER; ARTICLE; CELL COUNT; CELL INFILTRATION; CELL SUSPENSION; CELLULAR DISTRIBUTION; CILIARY BODY; CONTROLLED STUDY; ENUCLEATION; FEMALE; FLOW CYTOMETRY; HERPES SIMPLEX VIRUS 1; INOCULATION; INTERFERON PRODUCTION; IRIS; NONHUMAN; PRIORITY JOURNAL; VIRAL EYE INFECTION; ANIMAL; BAGG ALBINO MOUSE; BIOSYNTHESIS; FLUORESCENT ANTIBODY TECHNIQUE; HERPES SIMPLEX; IMMUNOELECTRON MICROSCOPY; IMMUNOLOGY; IMMUNOPHENOTYPING; IRIDOCYCLITIS; MACROPHAGE; METABOLISM; MOUSE; PATHOLOGY; PHYSIOLOGY; VIROLOGY;

ANIMALS; ANTERIOR CHAMBER; ANTIGENS, CD; ANTIGENS, DIFFERENTIATION; BIOLOGICAL MARKERS; EYE INFECTIONS, VIRAL; FEMALE; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; HERPES SIMPLEX; HERPESVIRUS 1, HUMAN; IMMUNOPHENOTYPING; INTEGRIN ALPHA2; INTERFERON-GAMMA; MACROPHAGE-1 ANTIGEN; MACROPHAGES; MICE; MICE, INBRED BALB C; MICROSCOPY, IMMUNOELECTRON; UVEITIS, ANTERIOR;

EID: 65549108375     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.08-2874     Document Type: Article

References (42)

1. Holland GN. Standard diagnostic criteria for the acute retinal necrosis syndrome: executive committee of the American Uveitis Society. Am J Ophthalmol. 1996;117:663-667.
2. Duker JS, Blumenkranz MS. Diagnosis and management of the acute retinal necrosis (ARN) syndrome. Surv Ophthalmol. 1991; 35:327-343.
3. Whittum J, McCulley J, Niederkorn JY, Streilein J. Ocular disease induced in mice by anterior chamber inoculation of herpes simplex virus. Invest Ophthalmol Vis Sci. 1984;25:1065-1073.
4. Vann VR, Atherton SS. Neural spread of herpes simplex virus after anterior chamber inoculation. Invest Ophthalmol Vis Sci. 1991;32: 2462-2472.
5. Bosem ME, Harris R, Atherton SS. Optic nerve involvement in viral spread in herpes simplex virus type 1 retinitis. Invest Ophthalmol Vis Sci. 1990;31:1683-1689.
6. Atherton S. Acute retinal necrosis: Insights into pathogenesis from the mouse model. Herpes. 2001;8:69-73.
7. Atherton S, Altman N, Streilein J. Histopathologic study of herpes virus-induced retinitis in athymic BALB/c mice: evidence for an immunopathogenic process. Curr Eye Res. 1989;8:1179-1191.
8. Atherton S, Vann V. Immunologic control of neural spread of herpes simplex virus type 1 (HSV-1) following anterior chamber inoculation. Proceedings of the Third International Symposium on Uveitis. Brussels, Belgium, May 24-27. Amsterdam: Kugler; 1992:23-28.
9. Matsubara S, Atherton SS. Spread of HSV-1 to the suprachiasmatic nuclei and retina in T-cell-depleted BALB/c mice. J Neuroimmunol. 1997;80:165-171.
10. Azumi A, Atherton SS. Sparing of the ipsilateral retina after anterior chamber inoculation of HSV-1: Requirement for either CD4 or CD8 T cells. Invest Ophthalmol Vis Sci. 1994;35:3251-3259.
11. Tanigawa M, Bigger JE, Kanter MY, Atherton SS. Natural killer cells prevent direct anterior-to-posterior spread of herpes simplex virus type 1 in the eye. Invest Ophthalmol Vis Sci. 2000;41:132-137.
12. Schroder K, Hertzog PJ, Ravasi T, Hume DA. Interferon-gamma: an overview of signals, mechanism and functions. J Leukoc Biol. 2004;75:163-189.
13. Takaoka A, Yanai H. Interferon signaling network in innate defense. Cell Microbiol. 2006;8:907-922.
14. Zheng M, Atherton SS. Cytokine profiles and inflammatory cells during HSV-1 induced acute retinal necrosis. Invest Ophthalmol Vis Sci. 2005;46:1356-1363.
15. Munder M, Mallo M, Eichmann K, Modolell M. Murine macrophages secrete interferon gamma upon combined stimulation with interleukin (IL)-12 and IL-18: a novel pathway of autocrine macrophage activation. J Exp Med. 1998;12:2103-2108.
16. Ethuin F, Gerard B, Benna JE, et al. Human neutrophils produce interferon gamma upon stimulation by interleukin-12. Lab Invest. 2004;84:1363-1371.
17. Theofilopoulos AN, Baccala R, Beutler B, Kono DH. Type I interferons (alpha/beta) in immunity and autoimmunity. Ann Rev Immunol. 2005;23:307-336.
18. Geiger K, Howes E, Sarvetnick N. Ectopic expression of gamma interferon in the eyes protects transgenic mice from intraocular herpes simplex virus type 1 infections. J Virol. 1994;68:5556-5567.
19. Bouley D, Kanangat S, Wire W, Rouse B. Characterization of herpes simplex virus type-1 infection and herpetic stromal keratitis development in IFN-gamma knockout mice. J Immunol. 1995;155: 3964-3971.
20. Geiger K, Nash T, Sawyer S, et al. Interferon-gamma protects against herpes simplex virus type 1-mediated neuronal death. Virology. 1997;238:189-197.
21. Hooks J, Wang Y, Detrick B. The critical role of IFN-gamma in experimental coronavirus retinopathy. Invest Ophthalmol Vis Sci. 2003;44:3402-3408.
22. Cantin E, Tanamachi B, Openshaw H, Mann J, Clarke K. Gamma interferon (IFNG) receptor null-mutant mice are more susceptible to herpes simplex virus type 1 infection than IFNG ligand nullmutant mice. J Virol. 1999;73:5196-5200.
23. Niemialtowski M, Rouse B. Phenotypic and functional studies on ocular T cells during herpetic infections of the eye. J Immunol. 1992;148:864-1870.
24. Zheng M, Fields MA, Liu Y, Cathcart HM, Richter E, Atherton SS. Neutrophils protect the retina from infection after anterior chamber inoculation of HSV-1 in BALB/c mice. Invest Ophthalmol Vis Sci. 2008;9:4018-4025.
25. Bogdan C, Schleicher U. Production of interferon-gamma by myeloid cells-fact or fancy? Trends Immunol. 2006;27:282-290.
26. Kawanokuchi J, Mizuno T, Takeuchi H, et al. Production of interferon-gamma by microglia. Mult Scler. 2006;12:558-564.
27. Atherton S, Streilein J. Two waves of virus following anterior chamber inoculation of HSV-1. Invest Ophthalmol Vis Sci. 1987; 28:571-579.
28. Roizman B, Knipe D. Fields Virology. 4th ed. Philadelphia, PA: Lippincott, Williams and Wilkins; 2001:2399-2459.
29. Nolte J. The Human Brain: an Introduction to Its Functional Anatomy. 5th ed. St. Louis, MO: Mosby; 2002:37-52.
30. Archin NM, van den Boom L, Perelygina L, Hilliard JM, Atherton SS. Delayed spread and reduction in virus titer after anterior chamber inoculation of a recombinant of HSV-1 expressing IL-16. Invest Ophthalmol Vis Sci. 2003;44:3066-3076.
31. Langmann T. Microglia activation in retinal degeneration. J Leukoc Biol. 2007;31:1345-1351.
32. Chen L, Yang P, Kijlstra A. Distribution, markers, and functions of retinal microglia. Ocul Immunol Inflamm. 2002;10:27-39.
33. Springer T, Galfre G, Secher DS, Milstein C. Mac-1: A macrophage differentiation antigen identified by monoclonal antibody. Eur J Immunol. 1979;9:301-306.
34. Ault KA, Springer TA. Cross-reaction of a rat-anti-mouse phagocytespecific monoclonal antibody (anti-Mac-1) with human monocytes and natural killer cells. J Immunol. 1981;126:359-364.
35. Kantor AB, Stall AM, Adams S, Herzenberg LA, Herzenberg LA. Differential development of progenitor activity for three B-cell lineages. Proc Natl Acad Sci U S A. 1992;89:3320-3324.
36. Lagasse E, Weissman IL. Flow cytometric identification of murine neutrophils and monocytes. J Immunol Methods. 1996;197:139-150.
37. Kerr E, Raveney B, Copland D, Dick A, Nicholson L. Analysis of retinal cellular infiltrate in experimental autoimmune uveoretinitis reveals multiple regulatory cell populations. J Autoimmun. 2008; 31(4):354-361.
38. Reading PC, Whitney PG, Barr DP, Smyth MJ, Brooks AG. NK cells contribute to the early clearance of HSV-1 from the lung but cannot control replication in the central nervous system following intranasal infection. Eur J Immunol. 2006;36:897-905.
39. Vollstedt S, Arnold S, Schwerdel C, et al. Interplay between alpha/ beta and gamma interferons with B, T, and natural killer cells in defense against herpes simplex virus type 1. J Virol. 2004;78: 3846-3850.
40. McMenamin PG. Dendritic cells and macrophages in the uveal tract of the normal mouse eye. Br J Ophthalmol. 1999;83:598-604.
41. Streilein JW. Ocular immune privilege: the eye takes a dim but practical view of immunity and inflammation. J Leukoc Biol. 2003; 74:179-185.
42. Colonna M, Trinchieri G, Liu Y-J. Plasmacytoid dendritic cells in immunity. Nat Immunol. 2004;5:1219-1226