메뉴 건너뛰기




Volumn 160, Issue 5, 2009, Pages 855-862

Genetic variation in exon 17 of INSR is associated with insulin resistance and hyperandrogenemia among lean Indian women with polycystic ovary syndrome

Author keywords

[No Author keywords available]

Indexed keywords

CYTOSINE; GENOMIC DNA; INSULIN RECEPTOR; THYMINE; INSR PROTEIN, HUMAN; LEUKOCYTE ANTIGEN;

EID: 65549096682     PISSN: 08044643     EISSN: 1479683X     Source Type: Journal    
DOI: 10.1530/EJE-08-0932     Document Type: Article
Times cited : (79)

References (42)
  • 1
    • 40349090138 scopus 로고    scopus 로고
    • Polycystic ovarian syndrome: Pathophysiology, molecular aspects and clinical implications
    • Diamanti-Kandarakis E. Polycystic ovarian syndrome: pathophysiology, molecular aspects and clinical implications. Expert Reviews in Molecular Medicine 2008 10 e3.
    • (2008) Expert Reviews in Molecular Medicine , vol.10
    • Diamanti-Kandarakis, E.1
  • 2
    • 0031456016 scopus 로고    scopus 로고
    • Insulin resistance and the polycystic ovary syndrome: Mechanism and implications for pathogenesis
    • Dunaif A. Insulin resistance and the polycystic ovary syndrome: mechanism and implications for pathogenesis. Endocrine Reviews 1997 18 774-800.
    • (1997) Endocrine Reviews , vol.18 , pp. 774-800
    • Dunaif, A.1
  • 5
    • 0032948363 scopus 로고    scopus 로고
    • Prevalence and predictors for risk for type 2 diabetes mellitus and impaired glucose tolerance in polycystic ovary syndrome: A prospective, controlled study in 254 affected women
    • Legro RS, Kunselman AR, DodsonWC & Dunaif A. Prevalence and predictors for risk for type 2 diabetes mellitus and impaired glucose tolerance in polycystic ovary syndrome: a prospective, controlled study in 254 affected women. Journal of Clinical Endocrinology and Metabolism 1999 84 165-169.
    • (1999) Journal of Clinical Endocrinology and Metabolism , vol.84 , pp. 165-169
    • Legro, R.S.1    Kunselman, A.R.2    DodsonWC3    Dunaif, A.4
  • 6
    • 33845889477 scopus 로고    scopus 로고
    • Insulin resistance in PCOS
    • Diamanti-Kandarakis E. Insulin resistance in PCOS. Endocrine 2006 30 13-17.
    • (2006) Endocrine , vol.30 , pp. 13-17
    • Diamanti-Kandarakis, E.1
  • 7
    • 21244465167 scopus 로고    scopus 로고
    • Changes in glucose tolerance over time in women with polycystic ovary syndrome: A controlled study
    • Legro RS, Finegood D & Dunaif A. Changes in glucose tolerance over time in women with polycystic ovary syndrome: a controlled study. Journal of Clinical Endocrinology and Metabolism 2005 90 3236-3242.
    • (2005) Journal of Clinical Endocrinology and Metabolism , vol.90 , pp. 3236-3242
    • Legro, R.S.1    Finegood, D.2    Dunaif, A.3
  • 11
    • 0027143817 scopus 로고    scopus 로고
    • Bjornthorp P. Hyperandrogenicity in women - a prediabetic condition? Journal of Internal Medicine 1993 234 609-613.
    • Bjornthorp P. Hyperandrogenicity in women - a prediabetic condition? Journal of Internal Medicine 1993 234 609-613.
  • 13
    • 0038369147 scopus 로고    scopus 로고
    • Glucose intolerance, insulin resistance, and hyperandrogenemia in first degree relatives of women with polycystic ovary syndrome
    • Yildiz BO, Yarali H, Oguz H & Bayraktar M. Glucose intolerance, insulin resistance, and hyperandrogenemia in first degree relatives of women with polycystic ovary syndrome. Journal of Clinical Endocrinology and Metabolism 2003 88 2031-2036.
    • (2003) Journal of Clinical Endocrinology and Metabolism , vol.88 , pp. 2031-2036
    • Yildiz, B.O.1    Yarali, H.2    Oguz, H.3    Bayraktar, M.4
  • 14
    • 17044370727 scopus 로고    scopus 로고
    • The molecular-genetic basis of functional hyperandrogenism and the polycystic ovary syndrome
    • Escobar-Morreale HF, Luque-Ramírez M & San Millán JL. The molecular-genetic basis of functional hyperandrogenism and the polycystic ovary syndrome. Endocrine Reviews 2005 26 251-282.
    • (2005) Endocrine Reviews , vol.26 , pp. 251-282
    • Escobar-Morreale, H.F.1    Luque-Ramírez, M.2    San Millán, J.L.3
  • 16
    • 0029119085 scopus 로고
    • Excessive insulin receptor serine phosphorylation in cultured fibroblasts and in skeletal muscle, A potential mechanism for insulin resistance in the polycystic ovary syndrome
    • Dunaif A, Xia J, Book CB, Schenker E & Tang Z. Excessive insulin receptor serine phosphorylation in cultured fibroblasts and in skeletal muscle, A potential mechanism for insulin resistance in the polycystic ovary syndrome. Journal of Clinical Investigation 1995 96 801-810.
    • (1995) Journal of Clinical Investigation , vol.96 , pp. 801-810
    • Dunaif, A.1    Xia, J.2    Book, C.B.3    Schenker, E.4    Tang, Z.5
  • 22
    • 0028047457 scopus 로고
    • Molecular scanning of the insulin receptor gene in syndromes of insulin resistance
    • Krook A, Kumar S, Laing I, Boulton AJ, Wass JA & O'Rahilly S. Molecular scanning of the insulin receptor gene in syndromes of insulin resistance. Diabetes 1994 43 357-368.
    • (1994) Diabetes , vol.43 , pp. 357-368
    • Krook, A.1    Kumar, S.2    Laing, I.3    Boulton, A.J.4    Wass, J.A.5    O'Rahilly, S.6
  • 24
    • 0030007155 scopus 로고    scopus 로고
    • SSCP analysis of the tyrosine kinase domain of the insulin receptor gene: Polymorphisms detected in South African black and white subjects
    • Panz VR, Ruff P, Joffe BI, Kedda MA & Seftel HC. SSCP analysis of the tyrosine kinase domain of the insulin receptor gene: polymorphisms detected in South African black and white subjects. Human Genetics 1996 7 438-440.
    • (1996) Human Genetics , vol.7 , pp. 438-440
    • Panz, V.R.1    Ruff, P.2    Joffe, B.I.3    Kedda, M.A.4    Seftel, H.C.5
  • 25
    • 0036902524 scopus 로고    scopus 로고
    • Siegel S, Futterweit W, Davies TF, Concepcion ES, Greenberg DA, Villanueva R & Tomer Y. A C/T single nucleotide polymorphism at the tyrosine kinase domain of the insulin receptor gene is associated with PCOS. Fertility and Sterility 2002 78 1240-1243.
    • Siegel S, Futterweit W, Davies TF, Concepcion ES, Greenberg DA, Villanueva R & Tomer Y. A C/T single nucleotide polymorphism at the tyrosine kinase domain of the insulin receptor gene is associated with PCOS. Fertility and Sterility 2002 78 1240-1243.
  • 26
    • 29244489787 scopus 로고    scopus 로고
    • Correlation between single nucleotide polymorphism of insulin receptor gene with polycystic ovary syndrome
    • Chen ZJ, Shi YH, Zhao YR, Li Y, Tang R, Zhao LX & Chang ZH. Correlation between single nucleotide polymorphism of insulin receptor gene with polycystic ovary syndrome. Zhonghua Fu Chan Ke Za Zhi 2004 39 582-585.
    • (2004) Zhonghua Fu Chan Ke Za Zhi , vol.39 , pp. 582-585
    • Chen, Z.J.1    Shi, Y.H.2    Zhao, Y.R.3    Li, Y.4    Tang, R.5    Zhao, L.X.6    Chang, Z.H.7
  • 27
    • 33746556803 scopus 로고    scopus 로고
    • Single nucleotide polymorphism in exon 17 of the insulin receptor gene is not associated with polycystic ovary syndrome in a Korean population
    • Lee EJ, Yoo KJ, Kim SJ, Lee SH, Cha KY & Baek KH. Single nucleotide polymorphism in exon 17 of the insulin receptor gene is not associated with polycystic ovary syndrome in a Korean population. Fertility and Sterility 2006 86 380-384.
    • (2006) Fertility and Sterility , vol.86 , pp. 380-384
    • Lee, E.J.1    Yoo, K.J.2    Kim, S.J.3    Lee, S.H.4    Cha, K.Y.5    Baek, K.H.6
  • 28
    • 33645838384 scopus 로고    scopus 로고
    • A novel SNP at exon 17 of INSR is associated with decreased insulin sensitivity in Chinese women with PCOS
    • Jin L, Zhu XM, Luo Q, Qian Y, Jin F & Huang HF. A novel SNP at exon 17 of INSR is associated with decreased insulin sensitivity in Chinese women with PCOS. Molecular Human Reproduction 2006 12 151-155.
    • (2006) Molecular Human Reproduction , vol.12 , pp. 151-155
    • Jin, L.1    Zhu, X.M.2    Luo, Q.3    Qian, Y.4    Jin, F.5    Huang, H.F.6
  • 29
    • 0346186090 scopus 로고    scopus 로고
    • The Rotterdam ESHRE/ASRM-sponsored PCOS consensus workshop group. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome (PCOS)
    • The Rotterdam ESHRE/ASRM-sponsored PCOS consensus workshop group. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome (PCOS). Human Reproduction 2004 19 41-47.
    • (2004) Human Reproduction , vol.19 , pp. 41-47
  • 31
    • 0016839114 scopus 로고
    • Plasma testosterone free index: A better indicator of plasma androgen activity?
    • Clark AF, Marcellus S, deLory B & Bird CE. Plasma testosterone free index: a better indicator of plasma androgen activity? Fertility and Sterility 1975 26 1001-1005.
    • (1975) Fertility and Sterility , vol.26 , pp. 1001-1005
    • Clark, A.F.1    Marcellus, S.2    deLory, B.3    Bird, C.E.4
  • 32
    • 0021813187 scopus 로고
    • Homeostasis model assessment: Insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man
    • Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF & Turner RC. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985 28 412-419.
    • (1985) Diabetologia , vol.28 , pp. 412-419
    • Matthews, D.R.1    Hosker, J.P.2    Rudenski, A.S.3    Naylor, B.A.4    Treacher, D.F.5    Turner, R.C.6
  • 34
    • 0043170938 scopus 로고    scopus 로고
    • Cutoff values for normal anthropometric variables in Asian Indian adults
    • Snehalatha C, Viswanathan V & Ramachandran A. Cutoff values for normal anthropometric variables in Asian Indian adults. Diabetes Care 2003 26 1380-1384.
    • (2003) Diabetes Care , vol.26 , pp. 1380-1384
    • Snehalatha, C.1    Viswanathan, V.2    Ramachandran, A.3
  • 35
    • 34547828961 scopus 로고    scopus 로고
    • The clinical biochemistry of obesity more than skin deep
    • Sikaris KA. The clinical biochemistry of obesity more than skin deep. Heart, Lung and Circulation 2007 16 S45-S50.
    • (2007) Heart, Lung and Circulation , vol.16
    • Sikaris, K.A.1
  • 38
    • 0024437305 scopus 로고
    • Profound peripheral insulin resistance, independent of obesity, in polycystic ovary syndrome
    • Dunaif A, Segal KR, Futterweit W & Dobrjansky A. Profound peripheral insulin resistance, independent of obesity, in polycystic ovary syndrome. Diabetes 1989 38 1165-1174.
    • (1989) Diabetes , vol.38 , pp. 1165-1174
    • Dunaif, A.1    Segal, K.R.2    Futterweit, W.3    Dobrjansky, A.4
  • 39
    • 42949093820 scopus 로고    scopus 로고
    • Evidence of subpopulations with different levels of insulin resistance in women with polycystic ovary syndrome
    • Vigil P, Contreras P, Alvarado JL, Godoy A, Salgado AM & Cortés ME. Evidence of subpopulations with different levels of insulin resistance in women with polycystic ovary syndrome. Human Reproduction 2007 11 2974-2980.
    • (2007) Human Reproduction , vol.11 , pp. 2974-2980
    • Vigil, P.1    Contreras, P.2    Alvarado, J.L.3    Godoy, A.4    Salgado, A.M.5    Cortés, M.E.6
  • 42
    • 0025946406 scopus 로고
    • Genetic variation in insulin receptor beta-chain exons among members of familial type 2 (non-insulin-dependent) diabetic pedigrees
    • Elbein SC & Sorensen LK. Genetic variation in insulin receptor beta-chain exons among members of familial type 2 (non-insulin-dependent) diabetic pedigrees. Diabetologia 1991 34 742-749.
    • (1991) Diabetologia , vol.34 , pp. 742-749
    • Elbein, S.C.1    Sorensen, L.K.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.