Synergetic effects of granulocyte-colony stimulating factor and cognitive training on spatial learning and survival of newborn hippocampal neurons

PLoS ONE

Volumn 4, Issue 4, 2009, Pages

  Diederich, Kai ^a   Schäbitz, Wolf Rüdiger ^a   Kuhnert, Katharina ^a   Hellström, Nina ^b   Sachser, Norbert ^a   Schneider, Armin ^c   Kuhn, Hans Georg ^b   Knecht, Stefan ^a  

^a UNIVERSITY OF MÜNSTER   (Germany)

^b UNIVERSITY OF GOTHENBURG   (Sweden)

^c SYGNIS Bioscience   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GRANULOCYTE COLONY STIMULATING FACTOR; LIGAND;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN NERVE CELL; CELL SURVIVAL; COGNITION; CONTROLLED STUDY; DRUG MECHANISM; HIPPOCAMPUS; LEARNING; MALE; MAZE TEST; MEMORY; NEWBORN; NONHUMAN; RAT; ANIMAL; BEHAVIOR; CYTOLOGY; DRUG EFFECT; GROWTH, DEVELOPMENT AND AGING; METABOLISM; NERVE CELL; NERVOUS SYSTEM DEVELOPMENT; WISTAR RAT;

RATTUS;

ANIMALS; CELL SURVIVAL; GRANULOCYTE COLONY-STIMULATING FACTOR; HIPPOCAMPUS; LIGANDS; MALE; MAZE LEARNING; MEMORY; NEUROGENESIS; NEURONS; RATS; RATS, WISTAR; SPATIAL BEHAVIOR;

EID: 65449152866     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0005303     Document Type: Article

References (42)

1. Schabitz WR, Schneider A (2007) New targets for established proteins: exploring G-CSF for the treatment of stroke. Trends Pharmacol Sci 28: 157-161.
2. Solaroglu I, Jadhav V, Zhang JH (2007) Neuroprotective effect of granulocyte-colony stimulating factor. Front Biosci 12: 712-724.
3. Schneider A, Kuhn HG, Schabitz WR (2005) A role for G-CSF (granulocyte-colony stimulating factor) in the central nervous system. Cell Cycle 4: 1753-1757.
4. Digicaylioglu M, Bichet S, Marti HH, Wenger RH, Rivas LA, et al. (1995) Localization of specific erythropoietin binding sites in defined areas of the mouse brain. Proc Natl Acad Sci U S A 92: 3717-3720.
5. Sosa L, Dupraz S, Laurino L, Bollati F, Bisbal M, et al. (2006) IGF-1 receptor is essential for the establishment of hippocampal neuronal polarity. Nat Neurosci 9: 993-995.
6. Ding Q, Vaynman S, Akhavan M, Ying Z, Gomez-Pinilla F (2006) Insulin-like growth factor I interfaces with brain-derived neurotrophic factor-mediated synaptic plasticity to modulate aspects of exercise-induced cognitive function. Neuroscience 140: 823-833.
7. Gilman CP, Perry T, Furukawa K, Grieg NH, Egan JM, et al. (2003) Glucagon-like peptide 1 modulates calcium responses to glutamate and membrane depolarization in hippocampal neurons. J Neurochem 87: 1137-1144.
8. Diano S, Farr SA, Benoit SC, McNay EC, da Silva I, et al. (2006) Ghrelin controls hippocampal spine synapse density and memory performance. Nat Neurosci 9: 381-388.
9. Schneider A, Kruger C, Steigleder T, Weber D, Pitzer C, et al. (2005) The hematopoietic factor G-CSF is a neuronal ligand that counteracts programmed cell death and drives neurogenesis. J Clin Invest 115: 2083-2098.
10. Mizuno K, Giese KP (2005) Hippocampus-dependent memory formation: do memory type-specific mechanisms exist? J Pharmacol Sci 98: 191-197.
11. Peters M, Mizuno K, Ris L, Angelo M, Godaux E, et al. (2003) Loss of Ca2+/ calmodulin kinase kinase beta affects the formation of some, but not all, types of hippocampus-dependent long-term memory. J Neurosci 23: 9752-9760.
12. Zhu DY, Lau L, Liu SH, Wei JS, Lu YM (2004) Activation of cAMP-response-element- binding protein (CREB) after focal cerebral ischemia stimulates neurogenesis in the adult dentate gyrus. Proc Natl Acad Sci U S A 101: 9453-9457.
13. Williams RW, Rakic P (1988) Three-dimensional counting: an accurate and direct method to estimate numbers of cells in sectioned material. J Comp Neurol 278: 344-352.
14. Kempermann G (2002) Why new neurons? Possible functions for adult hippocampal neurogenesis. J Neurosci 22: 635-638.
15. Maher P, Akaishi T, Abe K (2006) Flavonoid fisetin promotes ERK-dependent long-term potentiation and enhances memory. Proc Natl Acad Sci U S A 103: 16568-16573.
16. Sweatt JD (2004) Hippocampal function in cognition. Psychopharmacology (Berl) 174: 99-110.
17. Carlezon WA Jr, Duman RS, Nestler EJ (2005) The many faces of CREB. Trends Neurosci 28: 436-445.
18. Florian C, Mons N, Roullet P (2006) CREB antisense oligodeoxynucleotide administration into the dorsal hippocampal CA3 region impairs long- but not short-term spatial memory in mice. Learn Mem 13: 465-472.
19. Mizuno M, Yamada K, Maekawa N, Saito K, Seishima M, et al. (2002) CREB phosphorylation as a molecular marker of memory processing in the hippocampus for spatial learning. Behav Brain Res 133: 135-141.
20. Kempermann G, Gage FH (2002) Genetic determinants of adult hippocampal neurogenesis correlate with acquisition, but not probe trial performance, in the water maze task. Eur J Neurosci 16: 129-136.
21. Nottebohm F (2002) Neuronal replacement in adult brain. Brain Res Bull 57: 737-749.
22. Leuner B, Mendolia-Loffredo S, Kozorovitskiy Y, Samburg D, Gould E, et al. (2004) Learning enhances the survival of new neurons beyond the time when the hippocampus is required for memory. J Neurosci 24: 7477-7481.
23. Kempermann G, Kuhn HG, Gage FH (1997) More hippocampal neurons in adult mice living in an enriched environment. Nature 386: 493-495.
24. Gould E, Beylin A, Tanapat P, Reeves A, Shors TJ (1999) Learning enhances adult neurogenesis in the hippocampal formation. Nat Neurosci 2: 260-265.
25. Drapeau E, Montaron MF, Aguerre S, Abrous DN (2007) Learning-induced survival of new neurons depends on the cognitive status of aged rats. J Neurosci 27: 6037-6044.
26. Van Praag H, Schinder AF, Christie BR, Toni N, Palmer TD, et al. (2002) Functional neurogenesis in the adult hippocampus. Nature 415: 1030-1034.
27. Van Praag H, Kempermann G, Gage FH (1999) Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus. Nat Neurosci 2: 266-270.
28. Dobrossy MD, Drapeau E, Aurousseau C, Le Moal M, Piazza PV, et al. (2003) Differential effects of learning on neurogenesis: learning increases or decreases the number of newly born cells depending on their birth date. Mol Psychiatry 8: 974-982.
29. Ambrogini P, Orsini L, Mancini C, Ferri P, Ciaroni S, et al. (2004) Learning may reduce neurogenesis in adult rat dentate gyrus. Neurosci Lett 359: 13-16.
30. Epp JR, Spritzer MD, Galea LA (2007) Hippocampus-dependent learning promotes survival of new neurons in the dentate gyrus at a specific time during cell maturation. Neuroscience 149: 273-285.
31. Dupret D, Fabre A, Dobrossy MD, Panatier A, Rodriguez JJ, et al. (2007) Spatial learning depends on both the addition and removal of new hippocampal neurons. PLoS Biol 5: e214.
32. Couillard-Despres S, Winner B, Schaubeck S, Aigner R, Vroemen M, et al. (2005) Doublecortin expression levels in adult brain reflect neurogenesis. Eur J Neurosci 21: 1-14.
33. Greenough WT, Cohen NJ, Juraska JM (1999) New neurons in old brains: learning to survive? Nat Neurosci 2: 203-205.
34. Komine-Kobayashi M, Zhang N, Liu M, Tanaka R, Hara H, et al. (2006) Neuroprotective effect of recombinant human granulocyte colony-stimulating factor in transient focal ischemia of mice. J Cereb Blood Flow Metab 26: 402-413.
35. Solaroglu I, Tsubokawa T, Cahill J, Zhang JH (2006) Anti-apoptotic effect of granulocyte-colony stimulating factor after focal cerebral ischemia in the rat. Neuroscience 143: 965-974.
36. Schabitz WR, Kollmar R, Schwaninger M, Juettler E, Bardutzky J, et al. (2003) Neuroprotective effect of granulocyte colony-stimulating factor after focal cerebral ischemia. Stroke 34: 745-751.
37. Minnerup J, Heidrich J, Wellmann J, Rogalewski A, Schneider A, et al. (2008) Meta-analysis of the efficacy of granulocyte-colony stimulating factor in animal models of focal cerebral ischemia. Stroke 39: 1855-1861.
38. Meuer K, Pitzer C, Teismann P, Kruger C, Goricke B, et al. (2006) Granulocyte-colony stimulating factor is neuroprotective in a model of Parkinson's disease. J Neurochem 97: 675-686.
39. Cao XQ, Arai H, Ren YR, Oizumi H, Zhang N, et al. (2006) Recombinant human granulocyte colony-stimulating factor protects against MPTP-induced dopaminergic cell death in mice by altering Bcl-2/Bax expression levels. J Neurochem 99: 861-867.
40. Tsai KJ, Tsai YC, Shen CK (2007) G-CSF rescues the memory impairment of animal models of Alzheimer's disease. J Exp Med 204: 1273-1280.
41. Pitzer C, Kruger C, Plaas C, Kirsch F, Dittgen T, et al. (2008) Granulocyte-colony stimulating factor improves outcome in a mouse model of amyotrophic lateral sclerosis. Brain 131: 3335-3347.
42. Gibson CL, Bath PM, Murphy SP (2005) G-CSF reduces infarct volume and improves functional outcome after transient focal cerebral ischemia in mice. J Cereb Blood Flow Metab 25: 431-439.