Purification and immunological characterization of a 12-kDa allergen from Epicoccum purpurascens

FEMS Immunology and Medical Microbiology

Volumn 56, Issue 1, 2009, Pages 32-40

  Kukreja, Neetu ^a   Sridhara, Susheela ^a   Singh, Bhanu Pratap ^a   Gaur, Shailendra Nath ^b   Arora, Naveen ^a  

^a CSIR INSTITUTE OF GENOMICS AND INTEGRATIVE BIOLOGY   (India)

^b UNIVERSITY OF DELHI   (India)

Author keywords

Allergenicity; Epicoccum purpurascens; Fungal allergens; Purification

Indexed keywords

ALLERGEN; CONCANAVALIN A; IMMUNOGLOBULIN E; INTERLEUKIN 4; SEPHAROSE;

ALLERGIC ASTHMA; ALLERGIC RHINITIS; ARTICLE; BASOPHIL; CELL PROLIFERATION; CONTROLLED STUDY; DUST; ENZYME LINKED IMMUNOSORBENT ASSAY; EPICOCCUM PURPURASCENS; FUNGUS; GEL FILTRATION CHROMATOGRAPHY; HISTAMINE RELEASE; HUMAN; IMMUNOBLOTTING; IMMUNOLOGICAL PARAMETERS; IMMUNOREACTIVITY; MAJOR CLINICAL STUDY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MYCELIAL GROWTH; PERIPHERAL BLOOD MONONUCLEAR CELL; POLLEN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN PURIFICATION; SKIN MANIFESTATION; SKIN TEST; TH2 CELL;

ALLERGENS; ASCOMYCOTA; FUNGAL PROTEINS; HEMAGGLUTINATION INHIBITION TESTS; HISTAMINE RELEASE; HUMANS; HYPERSENSITIVITY; IMMUNOGLOBULIN E; INTRADERMAL TESTS; LYMPHOCYTE ACTIVATION; MOLECULAR WEIGHT; TANDEM MASS SPECTROMETRY;

EID: 65449124593     PISSN: 09288244     EISSN: 1574695X     Source Type: Journal    
DOI: 10.1111/j.1574-695X.2009.00542.x     Document Type: Article

References (37)

1. Akiyama K, Shida T, Yasueda H, Mita H, Yanagihara Y, Hasegawa M, Maeda Y, Yamamoto T, Takesako K Yamaguchi H (1996) Allergenicity of acid protease secreted by Candida albicans. Allergy 51 : 887 892. (Pubitemid 27077242)
2. Asturias JA, Ibarrola I, Ferrer A, Andreu C, López-Pascual E, Quiralte J, Florido F Martínez A (2005) Diagnosis of Alternaria alternata sensitization with natural and recombinant Alt a 1 allergens. J Allergy Clin Immun 115 : 1210 1217. (Pubitemid 40824591)
3. Ball T, Sperr WR, Valent P, Lidholm J, Spitzauer S, Ebner C, Kraft D Valenta R (1999) Induction of antibody responses to new B cell epitopes indicates vaccination character of allergen immunotherapy. Eur J Immunol 29 : 2026 2036. (Pubitemid 29265559)
4. Bisht V, Singh BP, Arora N, Sridhara S Gaur SN (2000) Allergens of Epicoccum nigrum grown in different media for quality source material. Allergy 55 : 274 280. (Pubitemid 30146124)
5. Bisht V, Singh BP, Arora N, Gaur SN Sridhara S (2002) Antigenic and allergenic cross-reactivity of Epicoccum nigrum with other fungi. Ann Allerg Asthma Im 89 : 285 291. (Pubitemid 36188028)
6. Bisht V, Arora N, Singh BP, Gaur SN Sridhara S (2004a) Purification and characterization of a major cross-reactive allergen from Epicoccum purpurascens. Int Arch Allergy Imm 133 : 217 224. (Pubitemid 38529213)
7. Bisht V, Arora N, Singh BP, Pasha S, Gaur SN Sridhara S (2004b) Epi p 1, an allergenic glycoprotein of Epicoccum purpurascens is a serine protease. FEMS Immunol Med Mic 42 : 205 211. (Pubitemid 39208548)
8. Bublin M, Radauer C, Wilson IB, Kraft D, Scheiner O, Breiteneder H Hoffmann-Sommergruber K (2003) Cross-reactive N-glycans of Api g 5, a high molecular weight glycoprotein allergen from celery, are required for immunoglobulin E binding and activation of effector cells from allergic patients. FASEB J 17 : 1697 1699.
9. Chou H, Lai HY, Tam MF, Chou MY, Wang SR, Han SH Shen HD (2002) cDNA cloning, biological and immunological characterization of the alkaline serine protease major allergen from Penicillium chrysogenum. Int Arch Allergy Imm 127 : 15 26. (Pubitemid 34224949)
10. Dhyani A, Arora N, Gaur SN, Jain VK, Sridhara S Singh BP (2006) Analysis of IgE binding proteins of Mesquite (Prosopis juliflora) pollen and cross-reactivity with predominant tree pollens. Immunobiology 211 : 733 740. (Pubitemid 44467741)
11. Dixit AB, Lewis WH Wedner HJ (1992) The allergens of Epicoccum nigrum Link. I. Identification of the allergens by immunoblotting. J Allergy Clin Immun 90 : 11 20.
12. Frostad AB, Grimmer O, Sandvik L, Moxnes A Aas K (1983) Clinical effects of hyposensitization using a purified allergen preparation from Timothy pollen as compared to crude aqueous extracts from Timothy pollen and a four-grass pollen mixture respectively. Clin Allergy 13 : 337 357.
13. Gupta R, Sharma V, Sridhara S, Singh BP Arora N (2004) Identification of serine protease as a major allergen of Curvularia lunata. Allergy 59 : 421 427. (Pubitemid 38406731)
14. Hino K, Yamamoto S, Sano O, Taniguchi Y, Kohno K, Usui M, Fukuda S, Hanzawa H, Haruyama H Kurimoto M (1995) Carbohydrate structures of the glycoprotein allergen Cry j I from japanese cedar (Cryptomeria japonica) pollen. J Biochem 117 : 289 295.
15. Hogan MB, Patterson R, Pore RS, Corder WT Wilson NW (1996) Basement shower hypersensitivity pneumonitis secondary to Epicoccum nigrum. Chest 110 : 854 856. (Pubitemid 27009323)
16. Hussein HS Brasel JM (2001) Toxicity, metabolism, and impact of mycotoxins on humans and animals. Toxicology 167 : 101 134. (Pubitemid 32916159)
17. Kleine Budde I, de Heer PG, van der Zee JS Aalberse RC (2001) The stripped basophil histamine release bioassay as a tool for the detection of allergen-specific IgE in serum. Int Arch Allergy Imm 126 : 277 285. (Pubitemid 34124193)
18. Kukreja N, Singh BP, Arora N, Gaur SN Sridhara S (2008a) Identification of Epicoccum purpurascens allergens by two-dimensional immunoblotting and mass spectrometry. Immunobiology 213 : 65 73.
19. Kukreja N, Sridhara S, Singh BP Arora N (2008b) Effect of proteolytic activity of Epicoccum purpurascens major allergen, Epi p 1 in allergic inflammation. Clin Exp Immunol 154 : 162 171.
20. Kurup VP, Sussman GL, Yeang HY, Elms N, Breiteneder H, Arif SA, Kelly KJ, Bansal NK Fink JN (2005) Specific IgE response to purified and recombinant allergens in latex allergy. Clin Mol Allergy 3 : 11. (Pubitemid 41522341)
21. Mari A, Schneider P, Wally V, Breitenbach M Simon-Nobbe B (2003) Sensitization to fungi: epidemiology, comparative skin tests, and IgE reactivity of fungal extracts. Clin Exp Allergy 33 : 1429 1438. (Pubitemid 37289941)
22. Moverare R, Elfman L, Vesterinen E, Metso T Haahtela T (2002) Development of new IgE specificities to allergenic components in birch pollen extract during specific immunotherapy studied with immunoblotting and Pharmacia CAP system. Allergy 57 : 423 430. (Pubitemid 34442156)
23. Niederberg TePas EC, Hoyte EG, McIntire JJ Umetsu DT (2004) Clinical efficacy of microencapsulated timothy grass pollen extract in grass-allergic individuals. Ann Allerg Asthma Im 92 : 25 31. (Pubitemid 38113628)
24. Noble JA, Crow SA, Ahearn DG Kuhn FA (1997) Allergic fungal sinusitis in the southeastern USA: involvement of a new agent Epicoccum nigrum Ehrenb. ex Schlecht. 1824. J Med Vet Mycol 35 : 405 409. (Pubitemid 28037532)
25. Okano M, Kino K, Takishita T, Hattori H, Ogawa T, Yoshino T, Yokoyama M Nishizaki K (2001) Roles of carbohydrates on Cry j 1, the major allergen of Japanese cedar pollen, in specific T-cell responses. J Allergy Clin Immun 108 : 101 108. (Pubitemid 32662239)
26. Rolland JM, Douglass J O'Hehir RE (2000) Allergen immunotherapy: current and new therapeutic strategies. Expert Opin Inv Drug 9 : 515 527. (Pubitemid 30119690)
27. Shankar J, Singh BP, Gaur SN Arora N (2006) Recombinant glutathione-S-transferase a major allergen from Alternaria alternata for clinical use in allergy patients. Mol Immunol 43 : 1927 1932.
28. Shore PA, Burkhalter A Cohn Jr. VH (1959) A method for the fluorometric assay of histamine in tissues. J Pharmacol Exp Ther 127 : 182 186.
29. Singh BP, Sridhara S, Arora N Gangal SV (1992) Evaluation of protein assay methods for pollen and fungal spore extracts. Biochem Int 27 : 477 484.
30. Stoscheck CM (1990) Quantitation of Protein. Method Enzymol 182 : 50 69. (Pubitemid 20154379)
31. Su NY, Yu CJ, Shen HD, Pan FM Chow LP (1999) Pen c 1, a novel enzymatic allergen protein from Penicillium citrinum. Purification, characterization, cloning and expression. Eur J Biochem 261 : 115 123 (erratum in: Eur J Biochem 1999 261: 821). (Pubitemid 29166075)
32. Towbin H, Staehelin T Gordon J (1979) Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. P Natl Acad Sci USA 76 : 4350 4354. (Pubitemid 9256559)
33. Verma J, Sridhara S, Rai D Gangal SV (1998) Isolation and immunobiochemical characterization of a major allergen (65 kDa) from Fusarium equiseti. Allergy 58 : 311 315. (Pubitemid 28125937)
34. Verma J, Singh BP, Sridhara S, Gaur SN Arora N (2003) Purification and characterization of a cross-reactive 45-kD major allergen of Fusarium solani. Int Arch Allergy Imm 130 : 193 199. (Pubitemid 36359522)
35. Vijay HM, Adebe M Kurup VP (2005) Alternaria and Cladosporium allergens and allergy. Mold Allergy, Biology and Pathogenesis (Kurup VP, ed), pp. 51 67. Research Signpost, India.
36. Yunginger JW, Jones RT, Nesheim ME Geller M (1980) Studies on Alternaria allergens. III. Isolation of a major allergenic fraction (ALT-I). J Allergy Clin Immun 66 : 138 147. (Pubitemid 10087514)
37. Zimmermann I, Bugalho de Almeida AA, Ulmer WT Park SH (1983) Histamine release into tracheal lumen and bronchial reactivity. Effect of local allergen administration on histamine release and bronchial reactivity. Res Exp Med 182 : 153 166.