Air pollution and survival within the Washington University-EPRI veterans cohort: Risks based on modeled estimates of ambient levels of hazardous and criteria air pollutants

Journal of the Air and Waste Management Association

Volumn 59, Issue 4, 2009, Pages 473-489

  Lipfert, Frederick W ^a   Wyzga, Ronald E ^b   Baty, Jack D ^c   Miller, J Philip ^c  

^a Environmental Consultant   (United States)

^b ELECTRIC POWER RESEARCH INSTITUTE   (United States)

^c WASHINGTON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AIR QUALITY; COAL COMBUSTION; DIESEL ENGINES; FOG; HAZARDS; METAL WORKING; NITROGEN OXIDES; NOISE POLLUTION; RISK ANALYSIS; RISK PERCEPTION; SENSITIVITY ANALYSIS; SULFUR DIOXIDE;

AMBIENT MEASUREMENT; ATMOSPHERIC DISPERSION MODELS; CRITERIA AIR POLLUTANTS; HAZARDOUS AIR POLLUTANTS; POLLUTANT EXPOSURES; STATISTICAL SIGNIFICANCE; TRAFFIC-RELATED POLLUTANTS; WASHINGTON UNIVERSITY;

ATMOSPHERIC MOVEMENTS;

CARBON; NITROGEN OXIDE; SULFATE; SULFUR DIOXIDE;

AIR POLLUTANT; AIR POLLUTION; AMBIENT AIR; ARTICLE; ATMOSPHERIC DISPERSION; COMBUSTION; EXHAUST GAS; METAL INDUSTRY; MORTALITY; PRIORITY JOURNAL; SMELTER; SURVIVAL; TRAFFIC; VETERAN;

EID: 65449123572     PISSN: 10962247     EISSN: 21622906     Source Type: Journal    
DOI: 10.3155/1047-3289.59.4.473     Document Type: Article

References (81)

1. Pope, C.A., III; Thun, M.J.; Namboodiri, M.M.; Dockery, D.W.; Evans, J.S.; Speizer, F.E.; Heath, C.W., Jr. Particulate Air Pollution as a Predictor of Mortality in a Prospective Study of U.S. Adults; Am. J. Respir. Crit. Care Med. 1995, 151, 669-674.
2. Jerrett, M.; Newbold. K.B.; Burnett, R.T.; Thurston, G.; Lall, R.; Pope, C.A., III; Ma, R.; De Luca, P.; Thun, M.; Calle, J.; Krewski, D. Geographies of Uncertainty in the Health Benefits of Air Quality Improvements; Stoch. Environ. Res. Risk Assess. 2007, 21, 511-522.
3. Krewski, D.; Burnett, R.T.; Goldberg, M.S.; Hoover, K.; Siemiatycki, J.; Abrahamowicz, M.; White, W.H. Reanalysis of the Harvard Six Cities Study and the American Cancer Society Study of Particulate Air Pollution and Mortality: Special Report Part I. Replication and Validation; Health Effects Institute: Cambridge, MA, 2000; http://www.healtheffects.org/Pubs/Rean-part1.pdf (accessed September 10, 2007).
4. Krewski, D.; Burnett, R.T.; Goldberg, M.S.; Hoover, K.; Siemiatycki, J.; Abrahamowicz, M.; White, W.H. Reanalysis of the Harvard Six Cities Study and the American Cancer Society Study of Particulate Air Pollution and Mortality: Special Report Part II. Sensitivity Analyses; Health Effects Institute: Cambridge, MA, 2000; http://www.healtheffects.org/Pubs/Rean-part2.pdf (accessed September 10, 2007).
5. Jerrett, M.; Burnett, R.T.; Ma, R.; Pope, C.A., III; Krewski, D.; Newbold, K.B.; Thurston, G.; Shi, Y.; Finkelstein, N.; Calle, E.E.; Thun, M.J. Spatial Analysis of Air Pollution and Mortality in Los Angeles; Epidemiology 2005, 16, 727-736.
6. Jerrett, M.; Burnett, R.; Ma, R.; Pope, C.A., III; Thun, M.; Calle, J.; Thurston, G.; Ito, K.; Ross, Z.; Krewski, D. Air Pollution and Mortality in New York City. Presented at the Annual Meeting of the Health Effects Institute, San Francisco, CA, 2006.
7. Krewski, D.; Jerrett, M.; Burnett, R.T.; Ma, R.; Hughes, E.; Shi, Y.; Turner, M.C.; Pope, C.A., III; Thurston, G.; Calle, E.E.; Thun, M.J. Available at: http://www.healtheffects.org/Slides/AnnConf/2008/Krewski.pdf (accessed November 5, 2008).
8. Lipfert, F.W.; Perry, H.M., Jr.; Miller, J.P.; Baty, J.D.; Wyzga, R.E.; Carmody, S.E. The Washington University-EPRI Veterans Cohort Mortality Study: Preliminary Results; Inhal. Toxicol. 2000, 12(Suppl 4), 41-73.
9. 2.5 Constituents and Related Air Quality Variables as Predictors of Survival in a Cohort of U.S. Military Veterans; Inhal. Toxicol. 2006, 18, 645-657.
10. Lipfert, F.W.; Wyzga, R.E.; Baty, J.D.; Miller, J.P. Traffic Density as a Surrogate Measure of Environmental Exposures in Studies of Air Pollution Health Effects: Long-Term Mortality in a Cohort of U.S. Veterans; Atmos. Environ. 2006, 40, 154-169.
11. Lipfert, F.W.; Wyzga, R.E.; Baty, J.D.; Miller, J.P. Vehicular Traffic Effects on Survival within the Washington University-EPRI Veterans Cohort: New Estimates and Sensitivity Studies; Inhal. Toxicol. 2008, 20, 949-960.
12. 1996 National Air Toxics Assessment; U.S. Environmental Protection Agency; available at http://www.epa.gov/ttn/atw/nata (accessed June 5, 2007).
13. 1999 National Air Toxics Assessment; U.S. Environmental Protection Agency; available at http://www.epa.gov/ttn/atw/nata1999/ (accessed June 5, 2007).
14. Rosenbaum, A.S.; Axelrad, D.A.; Woodruff, T.J.; Wei, Y.-H.; Ligocki, M.P.; Cohen, J.P. National Estimates of Outdoor Air Toxics Concentrations; J. Air & Waste Manage. Assoc. 1999, 49, 1138-1152.
15. Karamchandani, P.K.; Vijayaraghavan, K.; Seigneur, C. CMAQ-MADRID-APT Version 4.5.1 User's Guide; Electrical Power Research Institute: Palo Alto, CA, 2006.
16. Karamchandani, P.; Vijayaraghavan, K.; Chen, S.-Y.; Seigneur, C.; Edgerton, E.S. Plume-in-Grid Modeling for Particulate Matter; Atmos. Environ. 2006, 40, 7280-7297.
17. Pun, B.K.; Seigneur, C.; Bailey, E.M.; Gautney, L.L.; Douglas, S.G.; Haney, J.L.; Kumar, N. Response of Atmospheric Particulate Matter to Changes in Precursor Emissions: a Comparison of Three Air Quality Models; Environ. Sci. Technol. 2008, 42, 831-837.
18. Lipfert, F.W.; Wyzga, R.E. Statistical Considerations in Determining the Health Significance of Constituents of Airborne Particulate Matter; J. Air & Waste Manage. Assoc. 1999, 49, 182-189.
19. The Toxic Air Contamination Identification Process: Toxic Air Contaminants from Diesel-Fueled Engines, Fact Sheet; California Air Resources Board: Sacramento, CA, 1998; available at http://www.arb.ca.gov/ toxics/dieseltac/factsht1.pdf (accessed December 12, 2007).
20. Sexton, K.; Linder, S.H.; Marko, D.; Bethel, H.; Lupo, P.J. Comparative Assessment of Air Pollution-Related Health Risks in Houston; Environ. Health Perspect. 2007, 115, 1388-1393.
21. Somers, J. U.S. Environmental Protection Agency. Personal communication, November 14, 2007.
22. Vijayaraghavan, K.; Karamchandani, P.; Seigneur, C. Plume-in-Grid Modeling of Summer Air Pollution in Central California; Atmos. Environ. 2006, 40, 5097-5109.
23. 2.5 Sulfate and Nitrate Measurements in New York State: Evaluation and Comparison with Filter-Based Measurements; Atmos. Environ. 2006, 40, 192-205.
24. 3, in New York, NY; Atmos. Environ. 2003, 37, 2837-2844.
25. Wheeler, A.J.; Smith-Doiron, M.; Xu, X.; Gilbert, N.L.; Brook, J.R. Intra-Urban Variability of Air Pollution in Windsor, Ontario-Measurement and Modeling for Human Exposure Assessment; Environ. Res. 2008, 106, 7-16.
26. Restrepo, C.; Zimmerman, R.; Thurston, G.; Clemente, J.; Gorczynski, J.; Mianhua, Z.; Blaustein, M; Lung, C.C A Comparison of Ground-Level Air Quality Data with New York State Department of Environmental Conservation Monitoring Stations in South Bronx, New York; Atmos. Environ. 2004, 38, 5295-5304.
27. Comparison of ASPEN Modeling System Results to Monitored Concentrations; U.S. Environmental Protection Agency; available at http://www.epa.gov/ttn/atw/nata/draft6.html (accessed August 13, 2008).
28. DPM Model-To-Measurement Comparison, EPA 420-D-02-004; Prepared for U.S. Environmental Protection Agency by ICF Consulting: Fairfax, VA, 2002.
29. Lipfert, F.W. Air Pollution and Community Health; van Nostrand, Wiley: New York, 1994; pp 71-73.
30. Lipfert, F.W.; Wyzga, R.E. Effects of Exposure Error on Environmental Epidemiology. In Proceedings of the International Symposium on the Health Effects of Particulate Matter, Prague; VIP-80; A&WMA, Pittsburgh, PA, 1998; pp 155-166.
31. Lipfert, F.W. The Use and Misuse of Surrogate Variables in Environmental Epidemiology; J. Environ. Med. 1999, 1, 267-278.
32. National Air Quality and Emission Trends Report, 1999; Report EPA 454/R-01-004; U.S. Environmental Protection Agency; Washington, DC, 2001; Appendix A.
33. Mallick, R.; Fung, K.; Krewski, D. Adjusting for Measurement Error in the Cox Proportional Hazards Regression Model; J. Cancer Epidemiol. Prev. 2002, 7, 155-164.
34. HEI Air Toxics Review Panel, Mobile-Source Air Toxics: a Critical Review of the Literature on Exposure and Health Effects; HEI Special Report 16; Health Effects Institute, Boston, MA, 2007.
35. Touma, J.S.; Cox, W.M.; Tikvart, J.A. Spatial and Temporal Variability of Ambient Air Toxics Data; J. Air & Waste Manage. Assoc. 2006, 56, 1716-1725.
36. Baker, A.K.; Beyersdorf, A.J.; Doezema, L.A.; Katzenstein, A.; Meinardi, S.; Simpson, I.J.; Blake, D.R.; Rowland, F.S. Measurements of Non-methane Hydrocarbons in 28 United States Cities; Atmos. Environ. 2008, 42, 170-182.
37. Marshall, J.D.; Teoh S.-K.; Nzaroff, W.W. Intake Fraction of Nonreactive Vehicle Emissions in U.S. Urban Areas; Atmos. Environ. 2005, 39, 1363-1371.
38. Greco, S.L.; Wildon, A.M.; Spengler, J.D.; Levy, J.I. Spatial Patterns of Mobile Source Particulate Matter Emissions-to-Exposure Relationships across the United States; Atmos. Environ. 2007, 41, 1011-1025.
39. Ozkaynak, H.; Palma, T.; Touma, J.S.; Thurman, J. Modeling Population Exposures to Outdoor Sources of Hazardous Air Pollutants; J. Expo. Sci. Environ. Epidemiol. 2008, 18, 45-58.
40. Fruin, S.; Westerdahl, D.; Sax, T.; Sioutas, C.; Fine, P.M. Measurements and Predictors of On-Road Ultrafine Particle Concentrations and Associated Pollutants in Los Angeles; Atmos. Environ. 2008, 42, 207-219.
41. Karakitsios, S.P.; Papaloukas, C.L.; Kassomenos, P.A.; Pilidis, G.A. Assessment and Prediction of Exposure to Benzene of Filling Station Employees; Atmos. Environ. 2007, 41, 9555-9569.
42. Edgerton, S.A.; Holdren, M.W.; Smith, D.L.; Shah, J.J. Inter-Urban Comparison of Ambient Volatile Organic Compound Concentrations in U.S. Cities; J. Air Pollut. Control Assoc. 1989, 39, 729-732.
43. Ban-Weiss, G.A.; McLaughlin, J.P.; Harley, R.A.; Lunden, M.M.; Kirchstetter, T.W.; Kean, A.J.; Strawa, A.W.; Stevenson, E.D.; Kendall, G.R. Long-Term Changes in Emissions of Nitrogen Oxides and Particulate Matter from On-Road Gasoline and Diesel Engines; Atmos. Environ. 2008, 42, 220-232.
44. Louchouarn, P.; Chillrud, S.N.; Houel, S.; Yan, B.; Chaky, D.; Rumpel, C.; Largeau, C.; Bardoux, G.; Walsh, D.; Bopp, R.F. Elemental and Molecular Evidence of Soot- and Char-Derived Black Carbon Inputs to New York City's Atmosphere during the 20th Century; Environ. Sci. Technol. 2007, 41, 82-87.
45. Wakeham, S.G.; Forrest, J.; Masiello, C.A.; Gelinas, Y.; Alexander, C.R.; Leavitt, P.R. Hydrocarbons in Lake Washington Sediments. a 25-Year Retrospective in an Urban Lake; Environ. Sci. Technol. 2004, 38, 431-439.
46. Cook, R.; Strum, M.; Touma, J.S.; Palma, T.; Thurman, J.; Ensley, D.; Smith, R. Inhalation Exposure and Risk from Mobile Source Air Toxics in Future Years; J. Expo. Sci. Environ. Epidemiol. 2007, 17, 95-105.
47. Beckerman, B.; Jerrett, M.; Brook, J.R.; Verma, D.K.; Arain, M.A.; Finkelstein, M.M. Correlation of Nitrogen Dioxide with Other Traffic Pollutants near a Major Expressway; Atmos. Environ. 2008, 42, 275-290.
48. Scherer, G.; Urban, M.; Engl, J.; Hagedorn, H.W.; Riedel, K. Influence of Smoking Charcoal Filter Tipped Cigarettes on Various Biomarkers of Exposure; Inhal. Toxicol. 2006, 18, 821-829.
49. Berthoin, K.; Broekaert, F.; Robin, M.; Haufroid, V.; de Burbere, C.; Bernard, A. Serum Pneumoproteins and Biomarkers of Exposure to Urban Air Pollution: a Cross-Sectional Comparison of Policemen and Foresters; Biomarkers 2004, 9, 341-352.
50. Glass, G.E.; Sorensen, J.A.; Schemidt, K.W.; Rapp, G.R., Jr. New Source Identification of Mercury Contamination in the Great Lakes; Environ. Sci Technol. 1990, 24, 1059-1069.
51. Nadim, F.; Perkins, C.; Liu, S.; Carley, R.J.; Hoag, G.E. Long-Term Investigation of Atmospheric Mercury Contamination in Connecticut; Chemosphere 2001, 45, 1033-1043.
52. Landis, M.S.; Vette, A.F.; Keeler, G.J. Atmospheric Mercury in the Lake Michigan Basin: Influence of the Chicago/Gary Urban Area; Environ. Sci Technol. 2002, 36, 4508-4517.
53. Landis, M.S.; Lewis, C.W.; Stevens, R.K.; Keeler, G.J.; Dvonch, J.T.; Tremblay, R.T. Ft. McHenry Tunnel Study: Source Profiles and Mercury Emissions from Diesel and Gasoline Powered Vehicles; Atmos. Environ. 2007, 41, 8711-8724.
54. Wilhelm, S.M.; Kirchgessner, D. Mercury in U.S. Crude Oil: a Study by U.S. EPA, API, and NPRA; Society of Petroleum Engineers (SPE) Paper 80573; SPE: Richardson, TX, 2003.
55. Won, J.H.; Park, J.Y.; Lee, T.G. Mercury Emissions from Automobiles Using Gasoline, Diesel, and LPG; Atmos. Environ. 2007, 41, 7547-7552.
56. Huggins, F.E.; Huffman, G.P.; Linak, W.P.; Miller, C.A. Quantifying Hazardous Species in Particulate Matter Derived from Fossil-Fuel Combustion; Environ. Sci. Technol. 2004, 38, 1836-1842.
57. Lippmann, M.; Ito, K.; Hwang, J.-S.; Maciejczyk, P.; Chen, L.-C. Cardiovascular Effects of Nickel in Ambient Air; Environ. Health Perspect. 2006, 114, 1662-1669.
58. 2.5 in Tokyo, Japan; Atmos. Environ. 2007, 41, 7642-7668.
59. Meij, R.; te Winkel, H. The Emissions of Heavy Metals and Persistent Organic Pollutants from Modern Coal-Fired Power Stations; Atmos. Environ. 2007, 41, 9262-9272.
60. Schlesinger, R.B.; Kunzli, N.; Hidy, G.M.; Gotschi, T.; Jerrett, M. The Health Relevance of Ambient Particulate Matter Characteristics: Coherence of Toxicological and Epidemiological Inferences; Inhal. Toxicol. 2006, 18, 95-125.
61. Grahame, T.; Schlesinger, R. Evaluating the Health Risk from Secondary Sulfates in Eastern North American Regional Ambient Air Particulate Matter; Inhal. Toxicol. 2005, 17, 15-27.
62. Schlesinger, R.B.; Cassee, F. Atmospheric Secondary Inorganic Particulate Matter: the Toxicological Perspective as a Basis for Health Effects Risk Assessment; Inhal. Toxicol. 2003, 15, 197-235.
63. 2.5) in Ambient Air: a Critical Review; Inhal. Toxicol. 2007, 19, 811-832.
64. Cooke, R.M.; Wilson, A.M.; Tuomisto, J.T.; Moarales, O.; Taino, M.; Evans, J.S. A Probabilistic Characterization of the Relationship between Fine Particulate Matter and Mortality: Elicitation of European Experts; Environ. Sci. Technol. 2007, 41, 6598-6605.
65. 2.5 Concentration Extremes in New York City; Atmos. Environ. 2004, 38, 1547-1558.
66. Woodruff, T.J.; Axelrad, D.A.; Caldwell, J.; Morello-Frosch, R.; Rosenbaum, A. Public Health Implications of 1990 Air Toxics Concentrations across the United States; Environ. Health Perspect. 1998, 106, 245-251.
67. Wu, C.Y.; Pratt, G.C. Analysis of Air Toxics Emission Inventory: Inhalation Toxicity-Based Ranking; J. Air & Waste Manage. Assoc. 2001, 51, 1129-1141.
68. Ayres, J.G.; Borm, P.; Cassee, F.R.; Castranova, V.; Donaldson, K.; Ghio, A.; Harrison, R.M.; Hider, R.; Kelly, F.; Kooter, I.M.; Marano, F.; Maynard, R.L.; Mudway, I.; Nel, A.; Sioutas, C.; Smith, S.; Baeza-Squiban, A.; Cho, A.; Duggan, S.; Froines, J. Evaluating the Toxicity of Airborne Particulate Matter and Nanoparticles by Measuring Oxidative Stress Potential - a Workshop Report and Consensus Statement; Inhal. Toxicol. 2008, 20, 75-99.
69. Borm, P.J.; Kelly, F.; Kunzli, N.; Schins, R.P.; Donaldson, K. Oxidant Generation by Particulate Matter: from Biologically Effective Dose to a Promising, Novel Metric; Occup. Environ. Med. 2007, 64, 73-74.
70. Chang, C.C.; Hwang, J.S.; Chan, C.C.; Cheng, T.J. Interaction Effects of Ultrafine Carbon Black with Iron and Nickel on Heart Rate Variability in Spontaneously Hypertensive Rats; Environ. Health Perspect. 2007, 115, 1012-1017.
71. Chen, L.C.; Hwang, J.S. Effects of Subchronic Exposures to Concentrated Ambient Particles (CAPs) in Mice. IV. Characterization of Acute and Chronic Effects of Ambient Air Fine Particulate Matter Exposures on Heart-Rate Variability; Inhal. Toxicol. 2005, 17, 209-216.
72. Schwarze, P.E.; Ovrevik, J.; Lag, M.; Refsnes, M.; Nafstad, P.; Hetland, R.B.; Dybing, E. Particulate Matter Properties and Health Effects: Consistency of Epidemiological and Toxicological Studies; Hum Expos. Toxicol. 2006, 25, 559-579.
73. Elder, A.; Gelein, R.; Finkelstein, J.; Phipps, R.; Frampton, M.; Utell, M.; Kittelson, D.B.; Watts, W.F.; Hopke, P.; Jeong, C.H.; Kim, E.; Liu, W.; Zhao, W.; Zhuo, L.; Vincent, R.; Kumarathasan, P.; Oberdorster, G. On-Road Exposure to Highway Aerosols. 2. Exposures of Aged, Compromised Rats; Inhal. Toxicol. 2004, 16(Suppl 1), 41-53.
74. Kleinman, M.T.; Hamade, A.; Meacher, D.; Oldham, M.; Sioutas, C.; Chakrabarti, B.; Stram, D.; Froines, J.R.; Cho, A.K. Inhalation of Concentrated Ambient Particulate Matter near a Heavily Trafficked Road Stimulates Antigen-Induced Airway Responses in Mice; J. Air & Waste Manage. Assoc. 2005, 55, 1277-1288.
75. Campen, M.J.; McDonald, J.D.; Gigliotti, A.P.; Seilkop, S.K.; Reed, M.D.; Benson, J.M. Cardiovascular Effects of Inhaled Diesel Exhaust in Spontaneously Hypertensive Rats; Cardiovasc. Toxicol. 2003, 3, 353-361.
76. Campen, M.J.; Babu, N.S.; Helms, G.A.; Pett, S.; Wernly, J.; Mehran, R.; McDonald, J.D. Nonparticulate Components of Diesel Exhaust Promote Constriction in Coronary Arteries from ApoE-/- Mice; Toxicol. Sci. 2005, 88, 95-102.
77. Lund, A.K.; Knuckles, T.L.; Obot Akata, C.; Shohet, R.; McDonald, J.D.; Gigliotti, A.; Seagrave, J.C.; Campen, M.J. Gasoline Exhaust Emissions Induce Vascular Remodeling Pathways Involved in Atherosclerosis; Toxicol Sci. 2007, 95, 485-494.
78. Wellenius, G.A.; Coull, B.A.; Godleski, J.J.; Koutrakis, P.; Okabe, K.; Savage, S.T.; Lawrence, J.E.; Murthy, G.G.; Verrier, R.L. Inhalation of Concentrated Ambient Air Particles Exacerbates Myocardial Ischemia in Conscious Dogs; Environ. Health Perspect. 2003, 111, 402-408.
79. Steerenberg, P.A.; van Amelsvoort, L.; Lovik, M., Hetland, R.B.; Alberg, T.; Halatek, T.; Bloemen, H.J.; Rydzynski, K.; Swaen, G.; Schwarze, P.; Dybing, E.; Cassee, F.R. Relation between Sources of Particulate Air Pollution and Biological Effect Parameters in Samples from Four European cities: an Exploratory Study; Inhal. Toxicol. 2006, 18, 333-346.
80. Ovrevik, J.; Myran, T.; Refsnes, M.; Lag, M.; Becher, R.; Hetland, R.B.; Schwarze, P.E. Mineral Particles of Varying Composition Induce Differential Chemokine Release from Epithelial Lung Cells: Importance of Physico-Chemical Characteristics; Ann. Occup. Hyg. 2005, 49, 219-31.
81. Chang, C.C.; Hwang, J.S.; Chan, C.C.; Wang, P.Y.; Cheng, T.J. Effects of Concentrated Ambient Particles on Heart Rate, Blood Pressure, and Cardiac Contractility in Spontaneously Hypertensive Rats during a Dust Storm Event; Inhal. Toxicol. 2007, 19, 973-978.