Inhalation of concentrated ambient air particles exacerbates myocardial ischemia in conscious dogs

Environmental Health Perspectives

Volumn 111, Issue 4, 2003, Pages 402-408

  Wellenius, Gregory A ^a   Coull, Brent A ^a   Godleski, John J ^a,b   Koutrakis, Petros ^a   Okabe, Kazunori ^a,c   Savage, Sara T ^a   Lawrence, Joy E ^a   Murthy, G G Krishna ^a   Verrier, Richard L ^a,b,d  

^a HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

^d BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

Author keywords

Air particles; Air pollution; Cardiovascular disease; ECG; Myorcardial ischemia

Indexed keywords

SILICON DIOXIDE;

AMBIENT AIR; ANIMAL EXPERIMENT; ANIMAL MODEL; CARDIOVASCULAR RISK; CLIP; CONCENTRATION (PARAMETERS); CONSCIOUSNESS; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE EXACERBATION; DOG; DUST EXPOSURE; ELECTROCARDIOGRAM; ENVIRONMENTAL EXPOSURE; FEMALE; FILTRATION; HEART ARRHYTHMIA; HEART INFARCTION; HEART MUSCLE ISCHEMIA; HEART RATE; IMPLANTATION; NONHUMAN; PARTICLE SIZE; PARTICULATE MATTER; PRIORITY JOURNAL; RANDOMIZATION; REVIEW; ST SEGMENT ELEVATION; STATISTICAL SIGNIFICANCE; THORACOTOMY; URBAN AREA;

ANIMALIA; CANIS FAMILIARIS;

EID: 0037732821     PISSN: 00916765     EISSN: None     Source Type: Journal    
DOI: 10.1289/ehp.5775     Document Type: Review

References (49)

1. Ardehali A, Ports TA. 1990. Myocardial oxygen supply and demand. Chest 98:699-705.
2. Batalha JRF, Saldiva PHN, Clarke RW, Coull BA, Stearns RC, Lawrence J, et al. 2002. Concentrated ambient air particles induce vasoconstriction of small pulmonary arteries in rats. Environ Health Perspect 110:1191-1197.
3. Bouthillier L, Vincent R, Goegan P, Adamson IY, Bjarnason S, Stewart M, et al. 1998. Acute effects of inhaled urban particles and ozone: lung morphology, macrophage activity, and plasma endothelin-1. Am J Pathol 153:1873-1884.
4. Brooke RD, Brook JR, Urch B, Vincent R, Rajagopalan S, Silverman F. 2002. Inhalation of fine particulate pollution and ozone causes acute arterial vasoconstriction in healthy adults. Circulation 105:1534-1536.
5. Calderon-Garciduenas L, Gambling TM, Acuna H, Garcia R, Osnaya N, Monroy S, et al. 2001. Canines as sentinel species for assessing chronic exposures to air pollutants. II. Cardiac pathology. Toxicol Sci 61:356-367.
6. Chow JC, Watson JG, Pritchett LC, Pierson WR, Frazier CA, Purcell RG. 1993. The DRO thermal/optical reflectance carbon analysis system: description, evaluation and applications in US air quality studies. Atmos Environ 27A:1185-1201.
7. Clarke RW, Coull B, Reinisch U, Catalano P, Killingsworth CR, Koutrakis P, et al. 2000. Inhaled concentrated ambient particles are associated with hematologic and bronchoalveolar lavage changes in canines. Environ Health Perspect 108:1179-1187.
8. Dzubay TG, Stevens RK. 1975. Ambient air analysis with dichotomous sampler and x-ray fluorescence spectrometer. Environ Sci Technol 9:663-668.
9. Fisch C. 1997. Electrocardiography. In: Heart Disease: A Textbook of Cardiovascular Medicine (Brauwald E, ed). Philadelphia:W.B. Saunders Co., 108-152.
10. Galecki AT. 1994. General class of covariance structures for two or more repeated factors in longitudinal data analysis. Comm Stat Theory 23:3105-3119.
11. Godleski JJ, Verrier RL, Koutrakis P, Catalano P, Coull B, Reinisch U, et al. 2000. Mechanisms of morbidity and mortality from exposure to ambient air particles. Res Rep Health Eff Inst 91:5-88. Available: http://www.healtheffects.org/Pubs/Godleski.pdf [accessed 22 May 2002].
12. Hansen ADA, Rosen H, Novakov T. 1984. The aethalometer: an instrument for real-time measurement of optical absorption by aerosol particles. Sci Total Environ 36:191-196.
13. Heng MK, Singh BN, Norris R, John MB, Elliot R. 1976. Relationship between epicardial ST-segment elevation and myocardial ischemic damage after experimental coronary artery occlusion in dogs. J Clin Invest 58:1317-1326.
14. Irvin RG, Cobb FR. 1977. Relationship between epicardial ST-segment elevation, regional myocardial blood flow, and the extent of myocardial infarction in awake dogs. Circulation 55:825-832.
15. Kjekshus JK, Maroko PR, Sobel BE. 1972. Distribution of myocardial injury and its relation to epicardial ST-segment changes after coronary artery occlusion in the dog. Cardiovasc Res 6:490-499.
16. Kléber AG. 2000. ST-segment elevation in the electrocardiogram: a sign of myocardial ischemia. Cardiovasc Res 45:111-118.
17. Kobzik L, Goldsmith CW, Ning YY, Qin G, Morgan B, Imrich A, et al. 2001. Effects of combined ozone and air pollution particle exposure in mice. Res Rep Health Eff Inst 106:5-29. Available: http://www.healtheffects.org/Pubs/Kobzik.pdf [accessed 22 May 2002].
18. Koutrakis P, Sioutas C, Wolfson JM, Ferguson S. 1993. Development and evaluation of a glass honeycomb denuder/filter pack sampler to collect atmospheric gases and particles. Environ Sci Technol 27:2496-2501.
19. Koutrakis P, Wolfson JM, Spengler JD. 1988. An improved method for measuring aerosol acidity: results from a nine-month study in St. Louis MO, and Kingston TN. Atmos Environ 22:157-163.
20. Maroko PR, Kjekshus JK, Sobel BE, Watanabe T, Covell JW, Ross J Jr, et al. 1971. Factors influencing infarct size following experimental coronary artery occlusions. Circulation 43:67-82.
21. Marple VA, Rubow KL, Behm SM. 1991. A micro orifice uniform deposit impactor (MOUDI): description, calibration, and use. Aerosol Sci Technol 14:434-446.
22. Miguel AG, Cass GR, Glovsky MM, Weiss J. 1999. Allergens in paved road dust and airborne particles. Environ Sci Toxicol 33:4159-4168.
23. Oh JA, Suh HH, Lawrence JE, Allen GA, Koutrakis P. 1997. Characterization of particulate mass concentrations in South Boston, MA. In: Proceedings of AWMA/EPA Symposium on Measurement of Toxic and Related Air Pollutants, 29 April-1 May, Research Triangle Park, NC. AWMA publication VIP-74. Pittsburgh, PA:Air and Waste Management Association, 397-407.
24. Orton CE. 1995. Small Animal Thoracic Surgery. Baltimore, MD:Williams & Wilkins.
25. Patterson E, Burow RD, Hung CY, Scherlab BJ. 1993. Coronary vascular injury after transient coronary artery occlusion. Lab Invest 69:471-482.
26. Pekkanen J, Peters A, Hoek G, Tittanen P, Brunekreef B, de Hartog J. 2002. Particulate air pollution and risk of ST-segment depression during repeated submaximal exercise tests among subjects with coronary heart disease: The Exposure and Risk Assessment for Fine and Ultrafine Particles in Ambient Air (ULTRA) Study. Circulation 106:933-938.
27. Peters A, Dockery DW, Muller JE, Mittleman MA. 2001. Increased particulate air pollution and the triggering of myocardial infarction. Circulation 103:2810-2815.
28. Peters A, Liu E, Verrier RL, Schwartz J, Gold DR, Mittleman M, et al. 2000. Air pollution and incidence of cardiac arrhythmia. Epidemiology 11:11-17.
29. Poloniecki JD, Atkinson RW, de Leon AP, Anderson HR. 1997. Daily time series for cardiovascular hospital admissions and previous day's air pollution in London, UK. Occup Environ Med 54:535-540.
30. Rogge WF, Hildemann LM, Mazurek MA, Cass GR, Simoneit BRT. 1993. Sources of fine organic aerosol. III. Road dust, tire debris and organometallic brake lining dust - roads as sources and sinks. Environ Sci Technol 27:1892-1904.
31. Rooke GA, Feigl EO. 1982. Work as a correlate of canine left ventricular oxygen consumption, and the problem of catecholamine oxygen wasting. Circ Res 50:273-286.
32. SAS Institute, Inc. 1999. SAS/STAT User's Guide, Version 8. Cary, NC:SAS Institute, Inc.
33. Saldiva PHN, Clarke RW, Coull BA, Stearns RC, Lawrence J, Krishna Murthy GG, et al. 2002. Lung inflammation induced by concentrated ambient air particles is related to particle composition. Am J Respir Crit Care Med 165:1610-1617.
34. Santos UP, Lin CA, Pereira LAA, Vieira T, Braga ALF, Saldiva PHN, et al. 2001. Association between air pollution and cardiac arrhythmia in São Paulo, Brazil [Abstract]. Am J Respir Crit Care Med 163:A236.
35. Savage S, Lawrence J, Coull B, Okabe K, Wolde-Mariam W, Wellenius G, et al. 2002. Hematologic responses to inhalation of concentrated air particles (CAPs) and transient myocardial ischemia (MI) [Abstract]. Am J Respir Crit Care Med 165:A304.
36. Schauer JJ, Rogge WF, Hidemann LM, Mazurek MA, Cass GR, Simmoneit BRT. 1996. Source apportionment of airborne particulate matter using organic compounds as tracers. Atmos Environ 30:3837-3855.
37. Seaton A, Soutar A, Crawford V, Elton R, McNerlan S, Cherrie J, et al. 1999. Particulate air pollution and the blood. Thorax 54:1027-1032.
38. Sioutas C, Koutrakis P, Burton RM. 1995. A technique to expose animals to concentrated fine ambient aerosols. Environ Health Perspect 103:172-177.
39. Sioutas C, Koutrakis P, Godleski JJ, Ferguson ST, Kim CS, Burton RM. 1997. Fine particle concentrators for inhalation exposure- effect of particle size and composition. J Aerosol Sci 28:1057-1071.
40. Spengler J, Thurston G. 1983. Mass and elemental composition of fine and course particles in six US cities. J Air Pollut Control Assoc 3:1162-1171.
41. van Vliet P, Knape M, de Hartog J, Janssen N, Harssema H, Brunekreef B. 1997. Motor vehicle exhaust and chronic respiratory symptoms in children living near freeways. Environ Res 74:122-132.
42. Venables W, Ripley BD. 1994. Modern Applied Statistics with S-Plus. New York:Springer.
43. Venn AJ, Lewis SA, Cooper M, Hubbard R, Britton J. 2001. Living near a main road and the risk of wheezing illness in children. Am J Respir Crit Care Med 164:2177-2180.
44. Vincent R, Kumarathasan P, Goegan P, Bjarnason SG, Guenette J, Berube D, et al. 2001a. Inhalation toxicology of urban ambient particulate matter: acute cardiovascular effects in rats. Res Rep Health Eff Inst 104:5-54. Available: http://www.healtheffects.org/Pubs/Vincent.pdf [accessed 22 May 2002].
45. 2.5) causes elevations of the plasma vasopeptides endothelin ET-1 and ET-3 in humans [Abstract]. Am J Respir Crit Care Med 163:A313.
46. Watkinson WP, Campen MJ, Costa DL. 1998. Cardiac arrhythmia induction after exposure to residual oil fly ash particles in a rodent model of pulmonary hypertension. Toxicol Sci 41:209-216.
47. Wégria R, Segers M, Keating RP, Ward HP. 1949. Relationship between the reduction in coronary flow and the appearance of electrocardiographic changes. Am Heart J 38:90-96.
48. Wellenius GA, Saldiva PH, Batalha JR, Krishna Murthy GG, Coull BA, Verrier RL, et al. 2002. Electrocardiographic changes during exposure to residual oil fly ash (ROFA) particles in a rat model of myocardial infarction. Toxicol Sci 66:327-335.
49. Zar JH. 1996. Biostatistical Analysis. 3rd ed. Upper Saddle River, NJ:Prentice-Hall.