Human ubiquitin-protein ligase Nedd4: Expression, subcellular localization and selective interaction with ubiquitin-conjugating enzymes

Genes to Cells

Volumn 3, Issue 11, 1998, Pages 751-763

  Anan, Tadashi ^a   Nagata, Yoichi ^a   Koga, Hisashi ^a   Honda, Yoshiomi ^a   Yabuki, Nami ^b   Miyamoto, Chikara ^b   Kuwano, Akira ^c   Matsuda, Ichiro ^a   Endo, Fumio ^a   Saya, Hideyuki ^a   Nakao, Mitsuyoshi ^a  

^a KUMAMOTO UNIVERSITY   (Japan)

^b NIPPON ROCHE RESEARCH CENTER   (Japan)

^c EHIME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

LIGASE; UBIQUITIN;

ANIMAL CELL; ARTICLE; COVALENT BOND; DNA REPAIR; ENZYME ACTIVE SITE; ENZYME DEGRADATION; ENZYME LOCALIZATION; GENE DELETION; MEMBRANE TRANSPORT; NERVE CELL DIFFERENTIATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN EXPRESSION;

CELL DIFFERENTIATION; CELL NUCLEUS; CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 15; DOWN-REGULATION; HUMANS; LIGASES; NEURONS; PROTEIN BINDING; SEQUENCE DELETION; SUBCELLULAR FRACTIONS; TUMOR CELLS, CULTURED; UBIQUITIN-CONJUGATING ENZYMES; UBIQUITIN-PROTEIN LIGASES;

ANIMALIA;

EID: 6544291004     PISSN: 13569597     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2443.1998.00227.x     Document Type: Article

References (41)

1. Ciechanover, A. (1994) The ubiquitin-proteasome proteolytic pathway. Cell 79, 13-21.
2. Coux, O., Tanaka, K. & Goldberg, A.L. (1996) Structure and functions of the 20S and 26S proteasomes. Annu. Rev. Biochem. 65, 801-847.
3. Eisenmann, D.M., Arndt, K.M., Ricupero, S.L., Rooney, J.W. & Winston, E (1992) SPT3 interacts with TFIID to allow normal transcription in Saccharomyces cerevisiae. Genes Dev. 6, 1319-1331.
4. Galan, J.M., Moreau, V., Andre, B., Volland, C. & Haguenauer, T.R. (1996) Ubiquitination mediated by the Npi1p/Rsp5p ubiquitin-protein ligase is required for endocytosis of the yeast uracil permease. J Biol. Chem. 271, 10946-10952.
5. Gavva, N.R., Gavva, R., Ermekova, K., Sudol, M. & Shen, C.J. (1997) Interaction of WW domains with hematopoietic transcription factor p45/NF-E2 and RNA polymerase II. J. Biol. Chem. 272, 24105-24108.
6. Harvey, K.F., Harvey, N.L., Michael, J.M., et al. (1998) Caspase-mediated cleavage of the ubiquitin-protein ligase Nedd4 during apoptosis. J Biol. Chem. 273, 13524-13530.
7. Hatakeyama, S., Jensen, J.P. & Weissman, A.M. (1997) Subcellular localization and ubiquitin-conjugating enzyme (E2): interactions of mammalian HECT family ubiquitin protein ligases. J Biol. Chem. 272, 15085-15092.
8. Hein, C., Springael, J.Y., Volland, C., Haguenauer, T.R. & Andre, B. (1995) NPl1, an essential yeast gene involved in induced degradation of Gap1 and Fur4 permeases, encodes the R sp5 ubiquitin-protein ligase. Mol. Microbiol. 18, 77-87.
9. Hershko, A. & Ciechanover, A. (1992) The ubiquitin system for protein degradation. Annu. Rev. Biochem. 61, 761-807.
10. Hochstrasser, M. (1996a) Protein degradation or regulation: Ub the judge. Cell 84, 813-815.
11. Hochstrasser, M. (1996b) Ubiquitin-dependent protein degradation. Annu. Rev. Genet. 30, 405-439.
12. Hudson, T.J., Stein, L.D., Gerety, S.S., et al. (1995) An STS-based map of the human genome. Science 270, 1945-1954.
13. Huibregtse, J.M., Scheffner, M., Beaudenon, S. & Howley, P.M. (1995) A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase. Proc Natl. Acad. Sci. USA 92, 2563-2567.
14. Huibregtse, J.M., Scheffner, M. & Howley, P.M. (1993) Cloning and expression of the cDNA for E6:-AP, a protein that mediates the interaction of the human papillomavirus E6 oncoprotein with p53. Mol. Cell. Biol. 13, 775-784.
15. Huibregtse, J.M., Yang, J.C. & Beaudenon, S.L. (1997) The large subunit of RNA polymerase II is a substrate of the Rsp5 ubiquitin-protein ligase. Proc. Natl. Acad. Sci. USA 94, 3656-3661.
16. Imhof, M.O. & McDonnell, D.P. (1996) Yeast RSP5 and its human homolog hRPF1 potentiate hormone-dependent activation of transcription by human progesterone and glucocorticoid receptors. Mol. Cell. Biol. 16, 2594-2605.
17. Jennissen, H.P. (1995) Ubiquitin and the enigma of intracellular protein degradation. Eur. J. Biochem. 231, 1-30.
18. Jentsch, S. (1992) The ubiquitin-conjugation system. Annu. Rev. Genet. 26, 179-207.
19. Kumar, S., Harvey, K.F., Kinoshita, M., Copeland, N.G., Noda, M. & Jenkins, N.A. (1997a) cDNA cloning, expression analysis, and mapping of the mouse Nedd4 gene. Genomics 40, 435-443.
20. Kumar, S., Kao, W.H. & Howley P.M. (1997b) Physical interaction between specific E2 and Hect E3 enzymes determines functional cooperativity. J Biol. Chem. 272, 13548-13554.
21. Kumar, S., Tomooka, Y & Noda, M. (1992) Identification of a set of genes with developmentally down-regulated expression in the mouse brain. Biochem. Biophys. Res. Commun. 185, 1155-1161.
22. Kuwano, A., Ledbetter, S.A., Dobyns, W.B., Emanuel, B.S. & Ledbetter, D.H. (1991) Detection of deletions and cryptic translocations in Miller-Dieker syndrome by in situ hybridization. Am. J. Hum. Genet. 49, 707-714.
23. Mori, S., Tanaka, K., Kanaki, H., et al. (1997) Identification of an ubiquitin-ligation system for the epidermal-growth-factor receptor Herbimycin A induces in vitro ubiquitination in rabbit-reticulocyte lysate. Eur. J. Biochem. 247, 1190-1196.
24. Nagase, T., Miyajima, N., Tanaka, A., et al. (1995) Prediction of the coding sequences of unidentified human genes. III. The coding sequences of 40 new genes (KIAA0081-KIAA0120) deduced by analysis of cDNA clones from human cell line KG-1. DNA Res. 2, 37-43.
25. Nefsky B. & Beach, D. (1996) Pub1 acts as an E6-AP-like protein ubiquitin ligase in the degradation of cdc25. EMBO J. 15, 1301-1312.
26. Newton, A.C. (1995) Protein kinase C: structure, function, and regulation. J Biol. Chem. 270, 28495-28498.
27. van Nocker, S., Walker, J.M. & Vierstra, R.D. (1996) The Arabidopsis thdiana UBC7/13/14 genes encode a family of multiubiquitin chain-forming E2 enzymes. The Arabidopsis thaliana UBC7/13/14 genes encode a family of multiubiquitin chain-forming E2 enzymes. J Biol. Chem. 271, 12150-12158.
28. Nuber, U., Schwarz, S., Kaiser, P., Schneider, R. & Scheffner, M. (1996) Cloning of human ubiquitin-conjugating enzymes UbcH6 and UbcH7 (E2-F1) and characterization of their interaction with E6-AP and RSP5. J Biol. Chem. 271, 2795-2800.
29. Pagano, M., Tam, S.W., Theodoras, A.M., et al. (1995) Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27. Science 269, 682-685.
30. 18H mice. Nature Genet. 18, 143-146.
31. Pirozzi, G., McConnell, S.J., Uveges, A.J., et al. (1997) Identification of novel human WW domain- containing proteins by cloning of ligand targets. J Biol. Chem. 272, 14611-14616.
32. 2+-dependent plasma membranelocalization. J. Biol. Chem. 272, 32329-32336.
33. Scheffner, M., Huibregtse, J.M., Vierstra, R.D. & Howley, P.M. (1993) The HPV-16, E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53. Cell 75, 495-505.
34. Scheffner, M., Nuber, U. & Huibregtse, J.M. (1995) Protein ubiquitination involving an E1-E2-E3 enzyme ubiquitin thioester cascade. Nature 373, 81-83.
35. Staub, O., Dho, S., Henry, P., et al. (1996) WW domains of Nedd4 bind to the proline-rich PY motifs in the epithelial Na+ channel deleted in Liddle's syndrome. EMBO J. 15, 2371-2380.
36. Staub, O., Yeger, H., Plant, P.J., Kim, H., Ernst, S.A. & Rotin, D. (1997) Immunolocalization of the ubiquitin-protein ligase Nedd4 in tissues expressing the epithelial Na+ channel (ENaC). Am. J Physiol. 272(Cell Physiol. 41), C1871-C1880.
37. Sudol, M., Bork, P., Einbond, A., et al. (1995a) Characterization of the mammalian YAP (Yes-associated protein) gene and its role in defining a novel protein module, the WW domain. J. Biol. Chem. 270, 14733-14741.
38. Sudol, M., Chen, H.I., Bougeret, C., Einbond, A. & Bork, P. (1995b) Characterization of a novel protein-binding module - the WW domain. FEBS Lett. 369, 67-71.
39. Wiertz, E.J., Tortorella, D., Bogyo, M., et al. (1996) Sec61-mediated transfer of a membrane protein from the endoplasmic reticulum to the proteasome for destruction. Nature 384, 432-438.
40. Yamamoto, Y., Huibregtse, J.M. & Howley P.M. (1997) The human E6-AP gene (UBE3A) encodes three potential protein isoforms generated by differential splicing. Genomics 41, 263-266.
41. Yashiroda, H., Oguchi, T., Yasuda, Y., Toh, E.A. & Kikuchi, Y. (1996) Bull, a new protein that binds to the Rsp5 ubiquitin ligase in Saccharomyces cerevisiae. Mol. Cell. Biol. 16, 3255-3263.