Arsenic trioxide suppresses paclitaxel-induced mitotic arrest

Cell Proliferation

Volumn 42, Issue 3, 2009, Pages 404-411

  Duan, Q ^a,b,c   Komissarova, E ^c   Dai, W ^c  

^a Shanghai Jiao Tong University Affiliated Sixth People s Hospital   (China)

^b SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^c NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARSENIC TRIOXIDE; BUB1 RELATED PROTEIN; CELL CYCLE PROTEIN 20; CELL CYCLE PROTEIN 27; PACLITAXEL; PROTEIN P53; TUBULIN; UNCLASSIFIED DRUG;

ARTICLE; CELL CYCLE ARREST; CELL CYCLE PROGRESSION; CELL CYCLE S PHASE; CELL STRAIN HCT116; COMPARATIVE STUDY; CONTROLLED STUDY; FEMALE; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; HELA CELL; HUMAN; HUMAN CELL; INHIBITION KINETICS; MICROTUBULE ASSEMBLY; MITOSIS INHIBITION; PHARMACOLOGICAL BLOCKING; PROTEIN PHOSPHORYLATION; WESTERN BLOTTING;

ARSENICALS; BLOTTING, WESTERN; CELL LINE; FLOW CYTOMETRY; HUMANS; MICROSCOPY, FLUORESCENCE; MITOSIS; OXIDES; PACLITAXEL;

EID: 65349121199     PISSN: 09607722     EISSN: 13652184     Source Type: Journal    
DOI: 10.1111/j.1365-2184.2009.00606.x     Document Type: Article

References (35)

1. Halicka HD, Smolewski P, Darzynkiewicz Z, Dai W, Traganos F (2002) Arsenic trioxide arrests cells early in mitosis leading to apoptosis. Cell Cycle 1, 201 209.
2. Huang X (2003) The revival of the ancient drug - arsenic. Chin. Med. J. (Engl.) 116, 1637 1638. (Pubitemid 38008227)
3. Shen ZX, Chen GQ, Ni JH, Li XS, Xiong SM, Qiu QY et al 1997b) Use of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia (APL): II. Clinical efficacy and pharmacokinetics in relapsed patients. Blood 89, 3354 3360. (Pubitemid 27229822)
4. Soignet SL, Maslak P, Wang ZG, Jhanwar S, Calleja E, Dardashti LJ et al 1998) Complete remission after treatment of acute promyelocytic leukemia with arsenic trioxide. N. Engl. J. Med. 339, 1341 1348. (Pubitemid 28509343)
5. Zhang TD, Chen GQ, Wang ZG, Wang ZY, Chen SJ, Chen Z (2001) Arsenic trioxide, a therapeutic agent for APL. Oncogene 20, 7146 7153. (Pubitemid 33105004)
6. Kitamura K, Yoshida H, Ohno R, Naoe T (1997) Toxic effects of arsenic (As3+) and other metal ions on acute promyelocytic leukemia cells. Int. J. Hematol. 65, 179 185. (Pubitemid 27102080)
7. 4 cell apoptosis with downregulation of Bcl-2 expression and modulation of PML-RAR α/PML proteins. Blood 88, 1052 1061. (Pubitemid 26333331)
8. Zhu XH, Shen YL, Jing YK, Cai X, Jia PM, Huang Y et al 1999) Apoptosis and growth inhibition in malignant lymphocytes after treatment with arsenic trioxide at clinically achievable concentrations. J. Natl. Cancer Inst. 91, 772 778. (Pubitemid 29239056)
9. Rousselot P, Labaume S, Marolleau JP, Larghero J, Noguera MH, Brouet JC et al 1999) Arsenic trioxide and melarsoprol induce apoptosis in plasma cell lines and in plasma cells from myeloma patients. Cancer Res. 59, 1041 1048. (Pubitemid 29135964)
10. Siu KP, Chan JY, Fung KP (2002) Effect of arsenic trioxide on human hepatocellular carcinoma HepG2 cells: inhibition of proliferation and induction of apoptosis. Life Sci. 71, 275 285. (Pubitemid 34597190)
11. Shen ZY, Shen J, Cai WJ, Hong C, Zheng MH (2000) The alteration of mitochondria is an early event of arsenic trioxide induced apoptosis in esophageal carcinoma cells. Int. J. Mol. Med. 5, 155 158.
12. Uslu R, Sanli UA, Sezgin C, Karabulut B, Terzioglu E, Omay SB et al 2000) Arsenic trioxide-mediated cytotoxicity and apoptosis in prostate and ovarian carcinoma cell lines. Clin. Cancer Res. 6, 4957 4964. (Pubitemid 32110442)
13. Maeda H, Hori S, Nishitoh H, Ichijo H, Ogawa O, Kakehi Y et al 2001) Tumor growth inhibition by arsenic trioxide (As2O3) in the orthotopic metastasis model of androgen-independent prostate cancer. Cancer Res. 61, 5432 5440. (Pubitemid 32694923)
14. Murgo AJ (2001) Clinical trials of arsenic trioxide in hematologic and solid tumors: overview of the National Cancer Institute Cooperative Research and Development Studies. Oncologist. 6 (Suppl. 2 22 28. (Pubitemid 32405846)
15. Huang C, Li J, Ding M, Wang L, Shi X, Castranova V et al 2001) Arsenic-induced NFB transactivation through Erks- and JNKs-dependent pathways in mouse epidermal JB6 cells. Mol. Cell. Biochem. 222, 29 34. (Pubitemid 32910317)
16. Cai X, Shen YL, Zhu Q, Jia PM, Yu Y, Zhou L et al 2000) Arsenic trioxide-induced apoptosis and differentiation are associated respectively with mitochondrial transmembrane potential collapse and retinoic acid signaling pathways in acute promyelocytic leukemia. Leukemia 14, 262 270. (Pubitemid 30095381)
17. Larochette N, Decaudin D, Jacotot E, Brenner C, Marzo I, Susin SA et al 1999) Arsenite induces apoptosis via a direct effect on the mitochondrial permeability transition pore. Exp. Cell. Res. 249, 413 421. (Pubitemid 29397949)
18. Kligerman AD, Tennant AH (2007) Insights into the carcinogenic mode of action of arsenic. Toxicol. Appl. Pharmacol. 222, 281 288. (Pubitemid 47198270)
19. Cai X, Yu Y, Huang Y, Zhang L, Jia PM, Zhao Q et al 2003) Arsenic trioxide-induced mitotic arrest and apoptosis in acute promyelocytic leukemia cells. Leukemia 17, 1333 1337. (Pubitemid 36857340)
20. 2/M growth arrest and apoptosis after caspase-3 activation and Bcl-2 phosphorylation in promonocytic U937 cells. Biochem. Biophys. Res. Commun. 286, 726 734. (Pubitemid 32912948)
21. Li YM, Broome JD (1999a) Arsenic targets tubulins to induce apoptosis in myeloid leukemia cells. Cancer Res. 59, 776 780. (Pubitemid 29086725)
22. Ling YH, Jiang JD, Holland JF, Perez-Soler R (2002b) Arsenic trioxide produces polymerization of microtubules and mitotic arrest before apoptosis in human tumor cell lines. Mol. Pharmacol. 62, 529 538. (Pubitemid 36329371)
23. Ramirez P, Eastmond DA, Laclette JP, Ostrosky-Wegman P (1997) Disruption of microtubule assembly and spindle formation as a mechanism for the induction of aneuploid cells by sodium arsenite and vanadium pentoxide. Mutat. Res. 386, 291 298. (Pubitemid 27286301)
24. Jordan MA, Wilson L (2004) Microtubules as a target for anticancer drugs. Nat. Rev. Cancer 4, 253 265. (Pubitemid 38525281)
25. Castedo M, Perfettini JL, Roumier T, Andreau K, Medema R, Kroemer G (2004) Cell death by mitotic catastrophe: a molecular definition. Oncogene 23, 2825 2837. (Pubitemid 38638845)
26. Guo W, Tang XD, Tang S, Yang Y (2006) [Preliminary report of combination chemotherapy including Arsenic trioxide for stage III osteosarcoma and Ewing sarcoma]. Zhonghua Wai Ke. Za Zhi. 44, 805 808 (in Chinese).
27. Carre M, Carles G, Andre N, Douillard S, Ciccolini J, Briand C et al 2002a) Involvement of microtubules and mitochondria in the antagonism of arsenic trioxide on paclitaxel-induced apoptosis. Biochem. Pharmacol. 63, 1831 1842. (Pubitemid 34603447)
28. Ouyang B, Pan H, Lu L, Li J, Stambrook P, Li B et al 1997) Human Prk is a conserved protein serine/threonine kinase involved in regulating M phase functions. J. Biol. Chem. 272, 28646 28651. (Pubitemid 27517819)
29. Taylor BF, McNeely SC, Miller HL, Lehmann GM, McCabe MJ Jr., States JC (2006) p53 Suppression of arsenite-induced mitotic catastrophe is mediated by p21CIP1/WAF1. J. Pharmacol. Exp. Ther. 318, 142 151. (Pubitemid 43920751)
30. McNeely SC, Xu X, Taylor BF, Zacharias W, McCabe MJ Jr., States JC (2006) Exit from arsenite-induced mitotic arrest is p53 dependent. Environ. Health Perspect. 114, 1401 1406. (Pubitemid 44314764)
31. Ochi T, Nakajima F, Nasui M (1999) Distribution of gamma-tubulin in multipolar spindles and multinucleated cells induced by dimethylarsinic acid, a methylated derivative of inorganic arsenics, in Chinese hamster V79 cells. Toxicology 136, 79 88. (Pubitemid 29425798)
32. Yih LH, Lee TC (2000) Arsenite induces p53 accumulation through an ATM-dependent pathway in human fibroblasts. Cancer Res. 60, 6346 6352.
33. Salazar AM, Ostrosky-Wegman P, Menendez D, Miranda E, Garcia-Carranca A, Rojas E (1997) Induction of p53 protein expression by sodium arsenite. Mutat. Res. 381, 259 265. (Pubitemid 28015421)
34. Wassmann K, Benezra R (2001) Mitotic checkpoints: from yeast to cancer. Curr. Opin. Genet. Dev. 11, 83 90. (Pubitemid 32119283)
35. Cahill DP, Lengauer C, Yu J, Riggins GJ, Willson JK, Markowitz SD et al 1998) Mutations of mitotic checkpoint genes in human cancers. Nature 392, 300 303. (Pubitemid 28155105)