Adult neurogenesis and the pathogenesis of Alzheimer's disease

Medical Science Monitor

Volumn 15, Issue 3, 2009, Pages

  Taupin, Philippe ^a  

^a DUBLIN CITY UNIVERSITY   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID PRECURSOR PROTEIN; TAU PROTEIN;

ALZHEIMER DISEASE; ANEUPLOIDY; BRAIN DEGENERATION; BRAIN NERVE CELL; CELL CYCLE; CELL POPULATION; CHROMOSOME 17; CHROMOSOME 21; DENTATE GYRUS; DNA REPLICATION; HIPPOCAMPUS; HUMAN; LETTER; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; PATHOGENESIS; STEM CELL; ADULT; BRAIN; PATHOLOGY;

ADULT; ALZHEIMER DISEASE; ANEUPLOIDY; BRAIN; HUMANS; NEUROGENESIS;

EID: 65349111854     PISSN: 12341010     EISSN: 16433750     Source Type: Journal    
DOI: None     Document Type: Letter

References (7)

1. Taupin P: Adult neurogenesis pharmacology in neurological diseases and disorders. Ex Rev of Neurother, 2008; 8: 311-20
2. Jin K, Peel AL, Mao XO et al: Increased hippocampal neurogenesis in Alzheimer's disease. Proc Natl Acad Sci USA, 2004; 101: 343-47.
3. Migliore L, Botto N, Scarpato R et al: Preferential occurrence of chromosome 21 malsegregation in peripheral blood lymphocytes of Alzheimer disease patients. Cytogenet Cell Genet, 1999; 87: 41-46.
4. Potter H: Review and hypothesis: Alzheimer disease and Down syndrome - chromosome 21 nondisjunction may underlie both disorders. Am J Hum Genet, 1991; 48: 1192-200.
5. Herrup K, Arendt T: Re-expression of cell cycle proteins induces neuronal cell death during Alzheimer's disease. J Alzheimers Dis, 2002; 4: 243-47.
6. Yang Y, Mufson EJ, Herrup K: Neuronal cell death is preceded by cell cycle events at all stages of Alzheimer's disease. J Neurosci, 2003; 23: 2557-63.
7. Taupin P: Alzheimer's disease, aneuploidy and neurogenesis. Med Sci Monit, 2008; 14(5): LE6.