Inositol 1,4,5-trisphosphate 3-kinase B is a negative regulator of BCR signaling that controls B cell selection and tolerance induction

Journal of Immunology

Volumn 182, Issue 8, 2009, Pages 4696-4704

  Miller, Andrew T ^a   Beisner, Daniel R ^a   Liu, Daorong ^a   Cooke, Michael P ^a  

^a GENOMICS INSTITUTE OF THE NOVARTIS RESEARCH FOUNDATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; B LYMPHOCYTE RECEPTOR; BIM PROTEIN; BREAKPOINT CLUSTER REGION PROTEIN; CALCIUM CHANNEL; CALCIUM CHANNEL SOC; HEN EGG LYSOZYME; INOSITOL 1,3,4,5 TETRAKISPHOSPHATE; INOSITOL TRISPHOSPHATE 3 KINASE; INOSITOL TRISPHOSPHATE 3 KINASE B; LYSOZYME; UNCLASSIFIED DRUG; APOPTOSIS REGULATORY PROTEIN; BCL 2 LIKE PROTEIN 11; BCL-2-LIKE PROTEIN 11; CALCIUM; INOSITOL 1,4,5-TRISPHOSPHATE 3-KINASE; INOSITOL PHOSPHATE; INOSITOL-1,3,4,5-TETRAKISPHOSPHATE; LYMPHOCYTE ANTIGEN RECEPTOR; MEMBRANE PROTEIN; ONCOPROTEIN; PHOSPHOTRANSFERASE; PROTEIN KINASE INHIBITOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; B LYMPHOCYTE; BONE MARROW; CALCIUM SIGNALING; CELL SELECTION; CLONAL ANERGY; CONTROLLED STUDY; IMMUNOBLOTTING; IMMUNOLOGICAL TOLERANCE; MOUSE; NONHUMAN; PHENOTYPE; PRE B LYMPHOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; ANIMAL; C57BL MOUSE; CELL CULTURE; CELL DIFFERENTIATION; CYTOLOGY; DRUG EFFECT; ENZYMOLOGY; GENE DELETION; GENETICS; IMMUNOLOGY; METABOLISM; MOUSE MUTANT; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS REGULATORY PROTEINS; B-LYMPHOCYTES; BONE MARROW; CALCIUM; CELL DIFFERENTIATION; CELLS, CULTURED; GENE DELETION; IMMUNE TOLERANCE; INOSITOL PHOSPHATES; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS; RECEPTORS, ANTIGEN, B-CELL; SIGNAL TRANSDUCTION;

EID: 65249186856     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0802850     Document Type: Article

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