The mechanism of henipavirus fusion: Examining the relationships between the attachment and fusion glycoproteins

Virologica Sinica

Volumn 24, Issue 2, 2009, Pages 110-120

  Hickey, Andrew C ^a   Broder, Christopher C ^a  

^a UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

Author keywords

Hendra virus; Henipavirus; Nipah virus; Paramyxovirus; Viral entry

Indexed keywords

EPHRIN RECEPTOR; GLYCOPROTEIN; HN PROTEIN; MONOCLONAL ANTIBODY; THROMBOSPONDIN; VIRUS ENVELOPE PROTEIN; VIRUS FUSION PROTEIN; VIRUS HEMAGGLUTININ; VIRUS RECEPTOR;

AMINO ACID SEQUENCE; ARTICLE; GENE MUTATION; GENETIC IDENTIFICATION; GENETIC SUSCEPTIBILITY; HENDRA VIRUS; HENIPAVIRUS; HUMAN; INCIDENCE; MORBIDITY; MORTALITY; NEUROLOGIC DISEASE; NIPAH VIRUS; NONHUMAN; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; RECEPTOR BINDING; RESPIRATORY DISTRESS SYNDROME; VIRUS ENTRY; VIRUS INFECTION; VIRUS MORPHOLOGY; VIRUS TRANSMISSION; VIRUS VIRULENCE;

HENDRA VIRUS; HENIPAVIRUS; NIPAH VIRUS; PARAMYXOVIRIDAE;

EID: 65249170902     PISSN: 16740769     EISSN: 1995820X     Source Type: Journal    
DOI: 10.1007/s12250-009-3027-2     Document Type: Article

References (59)

1. Anonymous. 2008. Hendra Virus, Human, Equine - Australia (Queensland). International Society for Infectious Diseases. Report No.: 20080821.2606.
2. Anonymous. 2007. Hendra Virus, Human, Equine Australia, (Queensland): correction. International Society for Infectious Diseases. Report No.: 20070903.2896.
3. Anonymous. 2008. Nipah Virus, Fatal - Bangladesh (Dhaka). International Society for Infectious Diseases. Report No.: 20080311.0979.
4. Bishop K A, Broder C C. 2008. Hendra and Nipah: Lethal Zoonotic Paramyxoviruses. In: Emerging Infections (Scheld W M, Hammer S M, Hughes J M, ed.). Washington, D.C.: American Society for Microbiology.
5. Bishop K A, Hickey A C, Khetawat D, et al. 2008. Residues in the stalk domain of the hendra virus g glycoprotein modulate conformational changes associated with receptor binding. J Virol, 82(22): 11398-11409.
6. Bishop K A, Stantchev T S, Hickey A C, et al. 2007. Identification of hendra virus g glycoprotein residues that are critical for receptor binding. J Virol. 81(11): 5893-5901.
7. Bonaparte M I, Dimitrov A S, Bossart K N, et al. 2005. Ephrin-B2 ligand is a functional receptor for Hendra virus and Nipah virus. Proc Natl Acad Sci USA, 102(30): 10652-10657.
8. Bossart K N, Broder C C. 2009. Paramyxovirus Entry. In: Viral Entry into Host Cells (Pählmann S, Simmons G, ed.). Austin: TX Landes Bioscience.
9. Bossart K N, Crameri G, Dimitrov A S, et al. 2005. Receptor binding, fusion inhibition, and induction of cross-reactive neutralizing antibodies by a soluble g glycoprotein of hendra virus. J Virol, 79(11): 6690-6702.
10. Bossart K N, McEachern J A, Hickey A C, et al. 2007. Neutralization assays for differential henipavirus serology using Bio-Plex Protein Array Systems. J Virol Methods, 142(1-2): 29-40.
11. Bossart K N, Wang L F, Eaton B T, et al. 2001. Functional expression and membrane fusion tropism of the envelope glycoproteins of Hendra virus. Virology, 290(1): 121-135.
12. Bossart K N, Wang L F, Flora M N, et al. 2002. Membrane fusion tropism and heterotypic functional activities of the nipah virus and hendra virus envelope glycoproteins. J Virol, 76(22): 11186-11198.
13. Bowden T A, Aricescu A R, Gilbert R J, et al. 2008. Structural basis of Nipah and Hendra virus attachment to their cell-surface receptor ephrin-B2. Nat Struct Mol Biol, 15(6): 567-572.
14. Chua K B. 2003. Nipah virus outbreak in Malaysia. J Clin Virol, 26(3): 265-275.
15. Chua K B, Goh K J, Wong K T, et al. 1999. Fatal encephalitis due to Nipah virus among pig-farmers in Malaysia [see comments]. Lancet, 354(9186): 1257-1259.
16. Corey E A, Iorio R M. 2007. Mutations in the stalk of the measles virus hemagglutinin protein decrease fusion but do not interfere with virus-specific interaction with the homologous fusion protein. J Virol, 81(18): 9900-9910.
17. Deng R, Wang Z, Mirza A M, et al. 1995. Localization of a domain on the paramyxovirus attachment protein required for the promotion of cellular fusion by its homologous fusion protein spike. Virology, 209(2): 457-469.
18. Drescher U. 2002. Eph family functions from an evolutionary perspective. Curr Opin Genet Dev, 12(4): 397-402.
19. Eaton B T, Broder C C, Middleton D, et al. 2006. Hendra and Nipah viruses: Different and dangerous. Nat Rev Microbiol, 4(1): 23-35.
20. Eaton B T, Broder C C, Wang L F. 2005. Hendra and Nipah viruses: pathogenesis and therapeutics. Curr Mol Med, 5(8): 805-816.
21. Eaton B T, Mackenzie J S, Wang L-F. 2007. Henipaviruses. In: Fields Virology (Knipe D M, Howley P M, ed.). 5 ed. Philadelphia: Lippincott Williams & Wilkins. p. 1587-1600.
22. Epstein J H, Prakash V, Smith C S, et al. 2008. Henipavirus infection in fruit bats (Pteropus giganteus), India. Emerg Infect Dis, 14(8): 1309-1311.
23. Guillaume V, Aslan H, Ainouze M, et al. 2006. Evidence of a potential receptor-binding site on the Nipah virus G protein (NiV-G): identification of globular head residues with a role in fusion promotion and their localization on an NiV-G structural model. J Virol, 80(15): 7546-7554.
24. Gurley E S, Montgomery J M, Hossain M J, et al. 2007. Person-to-person transmission of Nipah virus in a Bangladeshi community. Emerg Infect Dis, 13(7): 1031-1037.
25. Harcourt B H, Lowe L, Tamin A, et al. 2005. Genetic characterization of Nipah virus, Bangladesh, 2004. Emerg Infect Dis, 11(10): 1594-1597.
26. Harit A K, Ichhpujani R L, Gupta S, et al. 2006. Nipah/Hendra virus outbreak in Siliguri, West Bengal, India in 2001. Indian J Med Res. 123(4): 553-560.
27. Hayman D T, Suu-Ire R, Breed A C, et al. 2008. Evidence of henipavirus infection in West African fruit bats. PLoS ONE, 3(7): E2739.
28. Heroult M, Schaffner F, Augustin H G. 2006. Eph receptor and ephrin ligand-mediated interactions during angiogenesis and tumor progression. Exp Cell Res, 312(5): 642-650.
29. Iorio R M, Mahon P J. 2008. Paramyxoviruses: Different receptors - different mechanisms of fusion. Trends Microbiol, 16(4): 135-137.
30. Krishanan S, Biswas K. 2007. Nipah Outbreak in India and Bangladesh. Newsletter: World Health Organization-South East Asia regional office.
31. Lamb R A, Jardetzky T S. 2007. Structural basis of viral invasion: lessons from paramyxovirus F. Curr Opin Struct Biol. 17(4): 427-436.
32. Lamb R A, Parks G D. 2007. Paramyxoviridae: The Viruses and Their Replication. In: Fields Virology (Knipe D M, Howley P M, ed.). 5 ed. Philadelphia: Lippincott Williams & Wilkins. p 1449-1496.
33. Lamb R A, Paterson R G, Jardetzky T S. 2006. Paramyxovirus membrane fusion: Lessons from the F and HN atomic structures. Virology, 344(1): 30-37.
34. Lawrence M C, Borg N A, Streltsov V A, et al. 2004. Structure of the haemagglutinin-neuraminidase from human parainfluenza virus type III. J Mol Biol, 335(5): 1343-1357.
35. Li Y, Wang J, Hickey A C, et al. 2008. Antibodies to Nipah or Nipah-like viruses in bats, China. Emerg Infect Dis. 14(12): 1974-1976.
36. Luby S P, Rahman M, Hossain M J, et al. 2006. Foodborne transmission of Nipah virus, Bangladesh. Emerg Infect Dis, 12(12): 1888-1894.
37. Melanson V R, Iorio R M. 2006. Addition of N-glycans in the stalk of the Newcastle disease virus HN protein blocks its interaction with the F protein and prevents fusion. J Virol, 80(2): 623-633.
38. Melanson V R, Iorio R M. 2004. Amino acid substitutions in the F-specific domain in the stalk of the newcastle disease virus HN protein modulate fusion and interfere with its interaction with the F protein. J Virol, 78(23): 13053-13061.
39. Morrison T G. 2001. The three faces of paramyxovirus attachment proteins. Trends Microbiol, 9(3): 103-105.
40. Murray G. 2006. Miscellaneous: Hendra Virus Findings in Queensland, Australia. Paris, France: World Organisation for Animal Health (OIE), www.oie.int. Report No.: Vol. 19 - No. 26.
41. Negrete O A, Levroney E L, Aguilar H C, et al. 2005. EphrinB2 is the entry receptor for Nipah virus, an emergent emergent deadly paramyxovirus. Nature, 436(7049): 401-405.
42. Pager C T, Craft W W, Jr Patch J, et al. 2006. A mature and fusogenic form of the Nipah virus fusion protein requires proteolytic processing by cathepsin L. Virology, 346(2): 251-257.
43. Pager C T, Dutch R E. 2005. Cathepsin L is involved in proteolytic processing of the hendra virus fusion protein. J Virol, 79(20): 12714-12720.
44. Pasquale E B. 2004. Eph-ephrin promiscuity is now crystal clear. Nat Neurosci, 7(5): 417-418.
45. Plemper R K, Hammond A L, Gerlier D, et al. 2002. Strength of envelope protein interaction modulates cytopathicity of measles virus. J Virol, 76(10): 5051-5061.
46. Poliakov A, Cotrina M, Wilkinson D G. 2004. Diverse roles of eph receptors and ephrins in the regulation of cell migration and tissue assembly. Dev Cell, 7(4): 465-480.
47. Reynes J M, Counor D, Ong S, et al. 2005. Nipah virus in Lyle's flying foxes, Cambodia. Emerg Infect Dis, 11(7): 1042-1047.
48. Russell C J, Jardetzky T S, Lamb R A. 2001. Membrane fusion machines of paramyxoviruses: Capture of intermediates of fusion. Embo J, 20(15): 4024-4034.
49. Stone-Hulslander J, Morrison T G. 1997. Detection of an interaction between the HN and F proteins in Newcastle disease virus-infected cells. J Virol, 71(9): 6287-6295.
50. Stone-Hulslander J, Morrison T G. 1999. Mutational analysis of heptad repeats in the membrane-proximal region of Newcastle disease virus HN protein. J Virol, 73(5): 3630-3637.
51. Takimoto T, Taylor G L, Connaris H C, et al. 2002. Role of the hemagglutinin-neuraminidase protein in the mechanism of paramyxovirus-cell membrane fusion. J Virol, 76(24): 13028-13033.
52. Tanabayashi K, Compans R W. 1996. Functional interaction of paramyxovirus glycoproteins: Identification of a domain in Sendai virus HN which promotes cell fusion. J Virol, 70(9): 6112-6118.
53. Tsurudome M, Kawano M, Yuasa T, et al. 1995. Identification of regions on the hemagglutinin-neuraminidase protein of human parainfluenza virus type 2 important for promoting cell fusion. Virology, 213(1): 190-203.
54. Wang B, Zhang N, Qian K X, et al. 2005. Conserved molecular players for axon guidance and angiogenesis. Curr Protein Pept Sci, 6(5): 473-478.
55. Wong K T, Shieh W J, Kumar S, et al. 2002. Nipah virus infection: pathology and pathogenesis of an emerging paramyxoviral zoonosis. Am J Pathol, 161(6): 2153-2167.
56. Xu K, Rajashankar K R, Chan Y P, et al. 2008. Host cell recognition by the henipaviruses: Crystal structures of the Nipah G attachment glycoprotein and its complex with ephrin-B3. Proc Natl Acad Sci USA, 105(29): 9953-9958.
57. Yu M, Hansson E, Langedijk J P, et al. 1998. The attachment protein of Hendra virus has high structural similarity but limited primary sequence homology compared with viruses in the genus Paramyxovirus. Virology, 251(2): 227-233.
58. Yuan P, Thompson T B, Wurzburg B A, et al. 2005. Structural studies of the parainfluenza virus 5 hemagglutinin-neuraminidase tetramer in complex with its receptor, sialyllactose. Structure (Camb), 13(5): 803-815.
59. Zhang J, Hughes S. 2006. Role of the ephrin and Eph receptor tyrosine kinase families in angiogenesis and development of the cardiovascular system. J Pathol, 208(4): 453-461.