Extraction of membrane cholesterol disrupts caveolae and impairs serotonergic (5-HT2A) and histaminergic (H1) responses in bovine airway smooth muscle: Role of Rho-kinase

Canadian Journal of Physiology and Pharmacology

Volumn 87, Issue 3, 2009, Pages 180-195

  Sommer, Bettina ^a   Montaño, Luis M ^b   Carbajal, Verónica ^a   Flores Soto, Edgar ^b   Ortega, Alicia ^c   Ramírez Oseguera, Ricardo ^b   Irles, Claudine ^c   El Yazbi, Ahmed F ^d   Cho, Woo Jung ^d   Daniel, Edwin E ^d  

^a INSTITUTO NACIONAL DE ENFERMEDADES RESPIRATORIAS   (Mexico)

^b UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

^c INSTITUTO NACIONAL DE PERINATOLOGÍA   (Mexico)

^d UNIVERSITY OF ALBERTA   (Canada)

Author keywords

5 HT2a receptor; Airway smooth muscle; Caveolae; Histamine h1 receptor; Lipid rafts; Rho kinase activity

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; CAVEOLIN 1; CHOLESTEROL; HISTAMINE H1 RECEPTOR; METHYL BETA CYCLODEXTRIN; RHO KINASE; SEROTONIN 2A RECEPTOR;

ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CAVEOLA; CONTROLLED STUDY; COW; IMMUNOBLOTTING; NONHUMAN; PRIORITY JOURNAL; SEROTONINERGIC SYSTEM; SMOOTH MUSCLE;

ANIMALS; BETA-CYCLODEXTRINS; CALCIUM; CATTLE; CAVEOLAE; CAVEOLIN 1; CHOLESTEROL; MEMBRANE LIPIDS; MUSCLE, SMOOTH; RECEPTOR, SEROTONIN, 5-HT2A; RECEPTORS, HISTAMINE H1; RHO-ASSOCIATED KINASES; SIGNAL TRANSDUCTION; TRACHEA;

EID: 65249152994     PISSN: 00084212     EISSN: None     Source Type: Journal    
DOI: 10.1139/Y08-114     Document Type: Article

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