Synergistic stabilization of nucleic acid assembly by 2'-O,4'-C-methylene- bridged nucleic acid modification and additions of comb-type cationic copolymers

Biochemistry

Volumn 48, Issue 15, 2009, Pages 3545-3553

  Torigoe, Hidetaka ^a   Maruyama, Atushi ^b,c   Obika, Satoshi ^d   Imanishi, Takeshi ^d   Katayama, Takuma ^a  

^a TOKYO UNIVERSITY OF SCIENCE   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^d OSAKA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACID MODIFICATIONS; ASSOCIATION RATE CONSTANTS; BINDING CONSTANTS; CATIONIC COPOLYMERS; CHEMICALLY MODIFIED; DISSOCIATION RATE CONSTANTS; KINETIC ANALYSIS; L LYSINES; MOLECULAR DESIGNS; ORDERS OF MAGNITUDES; POTENTIAL APPLICATIONS; SIDE CHAINS; STABILIZATION METHODS; STABILIZING EFFECTS; SYNERGISTIC EFFECTS; TRIPLEX FORMATIONS; TRIPLEX-FORMING OLIGONUCLEOTIDES;

AMINO ACIDS; BIOMOLECULES; COPOLYMERIZATION; DEXTRAN; DISSOCIATION; FORMING; GLUCOSE; GRAFTING (CHEMICAL); NUCLEIC ACIDS; OLIGONUCLEOTIDES; POLYMERS; RATE CONSTANTS;

STABILIZATION;

CARBENE; COPOLYMER; DEXTRAN; NUCLEIC ACID; OLIGONUCLEOTIDE; POLYLYSINE; POLYMER;

ARTICLE; BINDING AFFINITY; CHEMICAL REACTION; CHEMICAL STRUCTURE; DISSOCIATION CONSTANT; GEL MOBILITY SHIFT ASSAY; KINETICS; NUCLEIC ACID ANALYSIS; POLYMERIZATION; PRIORITY JOURNAL;

BASE PAIRING; DEXTRANS; DNA; DRUG SYNERGISM; KINETICS; NUCLEIC ACID CONFORMATION; NUCLEIC ACID HETERODUPLEXES; OLIGONUCLEOTIDES; POLYLYSINE;

EID: 65249139952     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi801795z     Document Type: Article

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