Identification of novel peptide ligands for the cancer-specific receptor mutation EFGRvIII using a mixture-based synthetic combinatorial library

Biopolymers

Volumn 91, Issue 3, 2009, Pages 201-206

  Denholt, Charlotte Lund ^a   Hansen, Paul Robert ^b   Pedersen, Nina ^a   Poulsen, Hans Skovgaard ^a   Gillings, Nic ^a   Kjær, Andreas ^a,b  

^a Rigshospitalet   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Cancer; Combinatorial library; Epidermal growth factor tyrosine kinase receptor mutation variant III (EGFRvIII)

Indexed keywords

AMINO ACID RESIDUES; BIOTIN-STREPTAVIDIN; BREAST CANCERS; CANCER; CANCER-SPECIFIC RECEPTORS; COMBINATORIAL LIBRARY; EPIDERMAL GROWTH FACTOR TYROSINE KINASE RECEPTOR MUTATION VARIANT III (EGFRVIII); EQUIMOLAR MIXTURES; GLIOBLASTOMAS; IMAGING AGENTS; NORMAL TISSUES; PEPTIDE LIGANDS; POSITRON EMISSIONS; PROTEINOGENIC AMINO ACIDS; SELECTIVE BINDINGS;

AMINATION; AMINO ACIDS; BIOACTIVITY; CHELATION; DIAGNOSTIC RADIOGRAPHY; LIGANDS; MIXTURES; ORGANIC ACIDS; PEPTIDES; POSITRON EMISSION TOMOGRAPHY; SCANNING; SYNTHESIS (CHEMICAL);

AMINES;

BIOTIN; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR TYROSINE KINASE RECEPTOR; STREPTAVIDIN; TUMOR MARKER; TYROSINE KINASE RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BREAST CANCER; COMBINATORIAL LIBRARY; CONTROLLED STUDY; GENE MUTATION; GENE TARGETING; GLIOBLASTOMA; ISOTOPE LABELING; LIGAND BINDING; MOUSE; MUTATIONAL ANALYSIS; NONHUMAN; OVARY CANCER; POSITRON EMISSION TOMOGRAPHY; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; RECEPTOR BINDING;

ANIMALS; CELL LINE; COMBINATORIAL CHEMISTRY TECHNIQUES; LIGANDS; MICE; MUTANT PROTEINS; MUTATION; NEOPLASMS; PEPTIDES; PROTEIN BINDING; RECEPTOR, EPIDERMAL GROWTH FACTOR;

EID: 65249133513     PISSN: 00063525     EISSN: 10970282     Source Type: Journal    
DOI: 10.1002/bip.21117     Document Type: Article

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