-
9
-
-
0141560467
-
-
(b) Qian, H. Biophys. Chem. 2003, 105, 585-593.
-
(2003)
Biophys. Chem
, vol.105
, pp. 585-593
-
-
Qian, H.1
-
13
-
-
0004178481
-
-
Herve, G, Ed, CRC Press: Boca Raton, FL
-
(c) Ricard, J. In Allosteric Enzymes; Herve', G., Ed.; CRC Press: Boca Raton, FL, 1989; pp 1-25.
-
(1989)
Allosteric Enzymes
, pp. 1-25
-
-
Ricard, J.1
-
14
-
-
46749083416
-
-
Qian, H Biophys. J. 2008, 95, 10-17.
-
(2008)
Biophys. J
, vol.95
, pp. 10-17
-
-
Qian, H.1
-
16
-
-
33644910749
-
-
(a) English, B. P.; Min, W.; van Oijen, A. M.; Lee, K. T.; Luo, G.; Sun, H.; Cherayil, B. J.; Kou, S. C.; Xie, S. X. Nat. Chem. Biol. 2006, 2, 87-94.
-
(2006)
Nat. Chem. Biol
, vol.2
, pp. 87-94
-
-
English, B.P.1
Min, W.2
van Oijen, A.M.3
Lee, K.T.4
Luo, G.5
Sun, H.6
Cherayil, B.J.7
Kou, S.C.8
Xie, S.X.9
-
17
-
-
27544450315
-
-
(b) Kou, S. C.; Cherayil, B. J.; Min, W.; English, B. P.; Xie, X. S. J. Phys. Chem. B 2005, 109, 19068-19081.
-
(2005)
J. Phys. Chem. B
, vol.109
, pp. 19068-19081
-
-
Kou, S.C.1
Cherayil, B.J.2
Min, W.3
English, B.P.4
Xie, X.S.5
-
19
-
-
33748096830
-
-
(b) Qian, H. J. Phys. Chem. B 2006, 110, 15063-15074.
-
(2006)
J. Phys. Chem. B
, vol.110
, pp. 15063-15074
-
-
Qian, H.1
-
20
-
-
27744499156
-
-
Eisenmesser, E. Z.; Millet, O.; Labeikovsky, W.; Korzhnev, D. M.; Wolf-Watz, M.; Bosco, D. A.; Skalicky, J. J.; Kay, L. E.; Kern, D. Nature 2005, 438, 117-121.
-
(2005)
Nature
, vol.438
, pp. 117-121
-
-
Eisenmesser, E.Z.1
Millet, O.2
Labeikovsky, W.3
Korzhnev, D.M.4
Wolf-Watz, M.5
Bosco, D.A.6
Skalicky, J.J.7
Kay, L.E.8
Kern, D.9
-
21
-
-
0004043557
-
-
Welch, G. R, Ed, John Wiley & Sons: New York
-
(a) The Fluctuating Enzyme; Welch, G. R., Ed.; John Wiley & Sons: New York, 1986.
-
(1986)
The Fluctuating Enzyme
-
-
-
22
-
-
0020014461
-
-
(b) Welch, G. R.; Somogyi, B.; Damjanovich, S. Prog. Biophys. Mol. Biol. 1982, 39, 109-146.
-
(1982)
Prog. Biophys. Mol. Biol
, vol.39
, pp. 109-146
-
-
Welch, G.R.1
Somogyi, B.2
Damjanovich, S.3
-
25
-
-
0035937443
-
-
Volkman, B. F.; Lipson, D.; Wemmer, D. E.; Kern, D. Science 2001, 291, 2429-2433.
-
(2001)
Science
, vol.291
, pp. 2429-2433
-
-
Volkman, B.F.1
Lipson, D.2
Wemmer, D.E.3
Kern, D.4
-
26
-
-
84906362860
-
-
Conformational changes, well studied at the time scale of milliseconds due to ligand bindings and/or chemical modifications, and conformational dynamics, as demonstrated by amide proton hydrogen exchange and molecular dynamic calculations occurring on the picosecond time scale, are often lumped together in most biochemical discussions. A more precise distinction perhaps can be made in terms of the single versus multiple states. For more discussion, see:
-
Conformational changes, well studied at the time scale of milliseconds due to ligand bindings and/or chemical modifications, and conformational dynamics, as demonstrated by amide proton hydrogen exchange and molecular dynamic calculations occurring on the picosecond time scale, are often lumped together in most biochemical discussions. A more precise distinction perhaps can be made in terms of the single versus multiple states. For more discussion, see:
-
-
-
-
27
-
-
0026320866
-
-
(a) Frauenfelder, H.; Sligar, S. G.; Wolynes, P. G. Science 1991, 254, 1598-1603.
-
(1991)
Science
, vol.254
, pp. 1598-1603
-
-
Frauenfelder, H.1
Sligar, S.G.2
Wolynes, P.G.3
-
28
-
-
0031582071
-
-
(b) Qian, H. J. Mol. Biol. 1997, 267, 198-206.
-
(1997)
J. Mol. Biol
, vol.267
, pp. 198-206
-
-
Qian, H.1
-
29
-
-
0013943915
-
-
Lumry, R.; Biltonen, R.; Brandts, J. F. Biopolymers 1966, 4, 917- 944.
-
(1966)
Biopolymers
, vol.4
, pp. 917-944
-
-
Lumry, R.1
Biltonen, R.2
Brandts, J.F.3
-
30
-
-
84906377093
-
-
In allosteric cooperativity, one of the differences between the Monod-Wyman-Changeux model and the Koshland-Nemethy-Filmer model is that the former has a two-state transition in response to ligand concentration while the latter has a single-state transition, see ref 1. In the MWC model, the T and R states always co-exist, irrespective of the ligand concentration. The ligand binding shifts the relative energy, and thus the relative population, between the T and R. In contrast, the KNF model has a gradual (in four steps) change of the tetramer structure with increasing ligand binding. There is a tighter coupling between the binding and the subunit structure in the KNF model
-
In allosteric cooperativity, one of the differences between the Monod-Wyman-Changeux model and the Koshland-Nemethy-Filmer model is that the former has a "two-state" transition in response to ligand concentration while the latter has a single-state transition, see ref 1. In the MWC model, the T and R states always co-exist, irrespective of the ligand concentration. The ligand binding shifts the relative energy, and thus the relative population, between the T and R. In contrast, the KNF model has a "gradual" (in four steps) change of the tetramer structure with increasing ligand binding. There is a tighter coupling between the binding and the subunit structure in the KNF model.
-
-
-
-
32
-
-
0031536149
-
-
(a) Jülicher, F.; Ajdari, A.; Prost, J. ReV. Mod. Phys. 1997, 69, 1269-1281.
-
(1997)
ReV. Mod. Phys
, vol.69
, pp. 1269-1281
-
-
Jülicher, F.1
Ajdari, A.2
Prost, J.3
-
33
-
-
0034310272
-
-
(b) Qian, H. J. Math. Chem. 2000, 27, 219-234.
-
(2000)
J. Math. Chem
, vol.27
, pp. 219-234
-
-
Qian, H.1
-
34
-
-
0004043557
-
-
Welch, G. R, Ed, John Wiley: New York
-
Volkenstein, M. V. In Fluctuating Enzyme; Welch, G. R., Ed.; John Wiley: New York, 1986; pp 403-419.
-
(1986)
Fluctuating Enzyme
, pp. 403-419
-
-
Volkenstein, M.V.1
-
36
-
-
38749105098
-
-
(b) Min, W.; Xie, X. S.; Bagchi, B. J. Phys. Chem. B 2008, 112, 454-466.
-
(2008)
J. Phys. Chem. B
, vol.112
, pp. 454-466
-
-
Min, W.1
Xie, X.S.2
Bagchi, B.3
-
43
-
-
33751265357
-
-
Min, W.; Gopich, I. V.; English, B. P.; Kou, S. C.; Xie, X. S.; Szabo, A. J. Phys. Chem. B 2006, 110, 20093-20097.
-
(2006)
J. Phys. Chem. B
, vol.110
, pp. 20093-20097
-
-
Min, W.1
Gopich, I.V.2
English, B.P.3
Kou, S.C.4
Xie, X.S.5
Szabo, A.6
-
50
-
-
0023661979
-
-
Mizraji, E.; Acerenza, L.; Lin, J. J. Theor. Biol. 1987, 129, 163- 175.
-
(1987)
J. Theor. Biol
, vol.129
, pp. 163-175
-
-
Mizraji, E.1
Acerenza, L.2
Lin, J.3
-
51
-
-
33748325882
-
-
Copeland, R. A.; Pompliano, D. L.; Meek, T. D. Nat. ReV. Drug DiscoVery 2006, 5, 730-739.
-
(2006)
Nat. ReV. Drug DiscoVery
, vol.5
, pp. 730-739
-
-
Copeland, R.A.1
Pompliano, D.L.2
Meek, T.D.3
-
52
-
-
84906377128
-
Phase diagram characterization of complex kinetics of fluctuating enzymes: Lessons from a minimal model
-
Manuscript in preparation
-
(a) Min, W.; Jiang, L.; Xie, X. S. Phase diagram characterization of complex kinetics of fluctuating enzymes: Lessons from a minimal model. Manuscript in preparation.
-
-
-
Min, W.1
Jiang, L.2
Xie, X.S.3
-
53
-
-
84906387243
-
Enzyme kinetics as a non-equilibrium steady-state cycle on a two-dimensional reaction free energy surface
-
Manuscript in preparation
-
(b) Min, W.; Xie, X. S.; Bagchi, B. Enzyme kinetics as a non-equilibrium steady-state cycle on a two-dimensional reaction free energy surface. Manuscript in preparation.
-
-
-
Min, W.1
Xie, X.S.2
Bagchi, B.3
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