Causes of transient instabilities in the dynamic clamp

IEEE Transactions on Neural Systems and Rehabilitation Engineering

Volumn 17, Issue 2, 2009, Pages 190-198

  Preyer, Amanda J ^a,b   Butera, Robert J ^c  

^a GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

^b AXION BIOSYSTEMS   (United States)

^c GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Action potential; Biological cells; Control systems; Nervous system

Indexed keywords

ACTION POTENTIAL; BIOLOGICAL CELLS; CAPACITANCE COMPENSATIONS; COMPUTATIONAL MODELS; FASTER RATES; ION CHANNELS; MEMBRANE VOLTAGES; NERVOUS SYSTEM; PHYSICAL EXPERIMENTS; SAMPLING EFFECTS; SAMPLING RATES; SERIES RESISTANCES; SINGLE ELECTRODES; TEMPORAL DYNAMICS; TRANSIENT INSTABILITIES;

CAPACITANCE; CELL MEMBRANES; DYNAMICS; SAMPLING;

SYSTEM STABILITY;

ANIMAL TISSUE; ARTICLE; CELL MEMBRANE POTENTIAL; CONDUCTANCE; ELECTRIC POTENTIAL; ELECTRODE; MATHEMATICAL MODEL; NERVE CELL; NERVE CELL NETWORK; NONHUMAN; PRIORITY JOURNAL; VOLTAGE CLAMP;

ACTION POTENTIALS; ANIMALS; APLYSIA; COMPUTER SIMULATION; ELECTROPHYSIOLOGY; GANGLIA, INVERTEBRATE; MEMBRANE POTENTIALS; MICROELECTRODES; MODELS, STATISTICAL; NERVOUS SYSTEM PHYSIOLOGICAL PHENOMENA; NEURAL CONDUCTION; NEURONS; PATCH-CLAMP TECHNIQUES; VERTEBRATES;

EID: 65249105455     PISSN: 15344320     EISSN: None     Source Type: Journal    
DOI: 10.1109/TNSRE.2009.2015205     Document Type: Article

References (48)

1. A. A. Sharp, M. B. O'Neil, L. F. Abbott, and E. Marder, "The dynamic clamp - Artificial conductances in biological neurons," Trends Neurosci., vol. 16, pp. 389-394, Oct. 1993.
2. A. A. Sharp, M. B. O'Neil, L. F. Abbott, and E. Marder, "Dynamic clamp - Computer-generated conductances in real neurons," J. Neurophysiol., vol. 69, pp. 992-995, Mar. 1993.
3. H. P. Robinson and N. Kawai, "Injection of digitally synthesized synaptic conductance transients to measure the integrative properties of neurons," J. Neurosci. Methods, vol. 49, pp. 157-65, Sep. 1993.
4. R. Wilders, E. E. Verheijck, R. Kumar, W. N. Goolsby, A. C. van Ginneken, R. W. Joyner, and H. J. Jongsma, "Model clamp and its application to synchronization of rabbit sinoatrial node cells," Amer. J. Physiol., vol. 271, pp. H2168-82, Nov. 1996.
5. T. A. Kinard, G. de Vries, A. Sherman, and L. S. Satin, "Modulation of the bursting properties of single mouse pancreatic b-cells by artificial conductances," Biophys. J., vol. 76, pp. 1423-35, Mar. 1999.
6. A. A. Prinz, L. F. Abbott, and E. Marder, "The dynamic clamp comes of age," Trends Neurosci., vol. 27, pp. 218-224, Apr. 2004.
7. R. Wilders, "Dynamic clamp: A powerful tool in cardiac electrophysi-ology," J. Physiol. (London), vol. 576, pp. 349-359, Oct. 2006.
8. J. M. Goaillard and E. Marder, "Dynamic clamp analyses of cardiac, endocrine, and neural function," Physiology, vol. 21, pp. 197-207, Jun. 2006.
9. D. Ulrich and J. R. Huguenard, "Gamma-aminobutyric acid type B receptor-dependent burst-firing in thalamic neurons: A dynamic clamp study," in Proc. Nat. Acad. Sci., Nov. 12, 1996, vol. 93, pp. 13245-9.
10. S. Gramoll, J. Schmidt, and R. L. Calabrese, "Switching in the activity state of an interneuron that controls coordination of the hearts in the medicinal leech (Hirudo medicinalis)," J. Exp. Biol., vol. 186, pp. 157-71, Jan. 1994.
11. + currents in frequency-dependent spike broadening in Aplysia R20 neurons: A dynamic-clamp analysis,"J. Neurosci., vol. 16, pp. 4089-101, Jul. 1996.
12. h) channel gene modifies the firing activity of identified motor neurons in a small neural network," J. Neurosci., vol. 23, pp. 9059-67, Oct. 2003.
13. A. A. Sharp, F. K. Skinner, and E. Marder, "Mechanisms of oscillation in dynamic clamp constructed two-cell half-center circuits," J. Neurophysiol., vol. 76, pp. 867-83, Aug. 1996.
14. A. J. Preyer and R. J. Butera, "Neuronal oscillators in aplysia californica that demonstrate weak coupling in vitro," Phys. Rev. Lett., vol. 95, p. 138103, Sep. 2005.
15. K. J. Suter and D. Jaeger, "Reliable control of spike rate and spike timing by rapid input transients in cerebellar stellate cells," Neuroscience, vol. 124, pp. 305-17, 2004.
16. L. Kreiner and D. Jaeger, "Synaptic shunting by a baseline of synaptic conductances modulates responses to inhibitory input volleys in cerebellar Purkinje cells," Cerebellum, vol. 3, pp. 112-25, 2004.
17. E. E. Verheijck, R. Wilders, R. W. Joyner, D. A. Golod, R. Kumar, H. J. Jongsma, L. N. Bouman, and A. C. van Ginneken, "Pacemaker synchronization of electrically coupled rabbit sinoatrial node cells," J. Gen. Physiol., vol. 111, pp. 95-112, Jan. 1998.
18. Y. Manor and F. Nadim, "Frequency regulation demonstrated by coupling a model and a biological neuron," Neurocomputing, vol. 38, pp. 269-278, Jun. 2001.
19. R. Wilders, R. Kumar, R. W. Joyner, H. J. Jongsma, E. E. Verheijck, D. Golod, A. C. van Ginneken, and W. N. Goolsby, "Action potential conduction between a ventricular cell model and an isolated ventricular cell," Biophys. J., vol. 70, pp. 281-95, Jan. 1996.
20. R. Kumar, R. Wilders, R. W. Joyner, H. J. Jongsma, E. E. Verheijck, D. A. Golod, A. C. van Ginneken, and W. N. Goolsby, "Experimental model for an ectopic focus coupled to ventricular cells," in Circulation, Aug. 15, 1996, vol. 94, pp. 833-41.
21. E. B. Merriam, T. I. Netoff, and M. I. Banks, "Bistable network behavior of layer I interneurons in auditory cortex," J. Neurosci., vol. 25, pp. 6175-86, Jun. 2005.
22. T. I. Netoff, M. I. Banks, A. D. Dorval, C. D. Acker, J. S. Haas, N. Kopell, and J. A. White, "Synchronization in hybrid neuronal networks of the hippocampal formation," J. Neurophysiol., vol. 93, pp. 1197-1208, Mar. 2005.
23. D. J. Huelsing, K. W. Spitzer, and A. E. Pollard, "Electrotonic suppression of early afterdepolarizations in isolated rabbit Purkinje myocytes," Am. J. Physiol. Heart Circ. Physiol., vol. 279, pp. H250-H259, Jul. 2000.
24. A. Strickholm, "A supercharger for single electrode voltage and current clamping," J. Neurosci. Methods, vol. 61, pp. 47-52, Oct. 1995.
25. S. F. Traynelis, "Software-based correction of single compartment series resistance errors," J. Neurosci. Methods, vol. 86, pp. 25-34, Dec. 1998.
26. A. J. Sherman, A. Shrier, and E. Cooper, "Series resistance compensation for whole-cell patch-clamp studies using a membrane state estimator," Biophys. J., vol. 77, pp. 2590-2601, Nov. 1999.
27. J. C. Bettencourt, K. P. Lillis, L. R. Stupin, and J. A. White, "Effects of imperfect dynamic clamp: Computational and experimental results," J. Neurosci. Methods, vol. 169, pp. 282-289, Apr. 2008.
28. T. Tateno and H. P. Robinson, "Rate coding and spike-time variablity in cortical neurons with two types of threshold dynamics," J. Neurophysiol., vol. 95, pp. 2650-2663, Apr. 2006.
29. A.J. Preyer, "A hardware implementation of the dynamic clamp," M.S. thesis, School Electrical Comput. Eng., Georgia Inst. Technol., Atlanta, GA, 2002.
30. G. Le Masson, "From conductances to neural network properties: Analysis of simple circuits using the hybrid network method," Prog. Biophys. Mol Biol., vol. 64, pp. 201-220, 1995.
31. C. C. Lien and P. Jonas, "Kv3 potassium conductance is necessary and kinetically optimized for high-frequency action potential generation in hippocampal interneurons," J. Neurosci., vol. 23, pp. 2058-2068, Mar. 2003.
32. H. P. Robinson, "A scriptable DSP-based system for dynamic conductance injection," J. Neurosci. Methods, vol. 169, pp. 271-281, Apr. 2008.
33. R. D. Pinto, R. C. Elson, A. Szucs, M. I. Rabinovich, A. I. Selverston, and H. D. I. Abarbanel, "Extended dynamic clamp: Controlling up to four neurons using a single desktop computer and interface," J. Neurosci. Methods, vol. 108, pp. 39-48, Jul. 2001.
34. R.J. Butera,C.G.Wilson, C. A.DelNegro, andJ. C. Smith,"Amethodology for achieving high-speed rates for artificial conductance injection in electrically excitable biological cells," IEEE Trans. Biomed. Eng., vol. 48, no. 12, pp. 1460-1470, Dec. 2001.
35. A.D.Dorval,D.J.Christini, andJ. A.White, "Real-time linux dynamic clamp:A fast and flexible wayto construct virtual ion channels inliving cells," Ann. Biomed. Eng., vol. 29, pp. 897-907, Oct. 2001.
36. I. Raikov, A. J. Preyer, and R. J. Butera, "MRCI: A flexible real-time dynamic clamp system for electrophysiology experiments," J. Neurosci. Methods, vol. 132, pp. 109-123, Jan. 2004.
37. R. J. Butera and M. L. McCarthy, "Analysis of real-time numerical integration methods applied to dynamic clamp experiments," J. Neural Eng., vol. 1, pp. 187-194, Dec. 2004.
38. R. L. Calabrese, private communication, 2008.
39. T. I. Netoff, private communication, 2008.
40. A. A. Prinz, private communication, 2008.
41. L. Brizzi, C. Meunier, D. Zytnicki, M. Donnet, D. Hansel, B. L. D'In-camps, and C. Van Vreeswijk, "How shunting inhibition affects the discharge of lumbar motoneurones: A dynamic clamp study in anaesthetized cats," J. Physiol., vol. 558, pp. 671-83, Jul. 2004.
42. A. J. Preyer and R. J. Butera, "The effect of residual electrode resistance and sampling delay on transient instability in the dynamic clamp system," in Conf. Proc. IEEE Eng. Med. Biol. Soc., 2007, vol. 2007, pp. 430-433.
43. T. Nowotny, V. P. Zhigulin, A. I. Selverston, H. D. I. Abarbanel, and M. I. Rabinovich, "Enhancement of synchronization in a hybrid neural circuit by spike-timing dependent plasticity," J. Neurosci., vol. 23, pp. 9776-9785, Oct. 2003.
44. C. J. Wilson and M. R. Park, "Capacitance compensation and bridge balance adjustment in intracellular recording from dendritic neurons," J. Neurosci. Methods, vol. 27, pp. 51-75, Feb. 1989.
45. J. W. Moore and F. Ramon, "On numerical integration of the Hodgkin and Huxley equations for a membrane action potential," J. Theor. Biol., vol. 45, pp. 249-73, May 1974.
46. S. Rush and H. Larsen, "A practical algorithm for solving dynamic membrane equations," IEEE Trans. Biomed. Eng., vol. 25, no. 4, pp. 389-92, Jul. 1978.
47. J. Magistretti, M.Mantegazza, M. de Curtis, and E. Wanke, "Modalities of distortionof physiological voltage signals by patch-clamp," Biophys. J., vol. 74, no. 2, pt. 1, pp. 831-842, Feb. 1998.
48. R. Brette, Z. Piwkowska, M. Rudolph, T. Bal, and A. Destexhe, "A non-parametric electrode model for intracellular recording," Neurocomputing, vol. 70, pp. 1597-1601, 2007.