Model clamp and its application to synchronization of rabbit sinoatrial node cells

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 271, Issue 5 40-5, 1996, Pages

  Wilders, Ronald ^a   Verheijck, E Etienne ^b   Kumar, Rajiv ^b   Goolsby, William N ^b   Van Ginneken, Antoni C G ^b   Joyner, Ronald W ^b   Jongsma, Habo J ^b  

^a UTRECHT UNIVERSITY   (Netherlands)

^b NONE

Author keywords

action potentials; computer simulation; electrophysiology; gap junctions; intercellular coupling

Indexed keywords

ACTION POTENTIAL; ANIMAL CELL; ARTICLE; CELL ISOLATION; CELL SYNCHRONIZATION; ELECTROPHYSIOLOGY; FEMALE; HEART MUSCLE CELL; MALE; MATHEMATICAL MODEL; NONHUMAN; PRIORITY JOURNAL; RABBIT; SINUS NODE;

EID: 33750708307     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.1996.271.5.h2168     Document Type: Article

References (36)

1. Anumonwo, J. M. B., M. Delmar, A. Vinet, D. C. Michaels, and J. Jalife. Phase resetting and entrainment of pacemaker activity in single sinus nodal cells. Circ. Res. 68: 1138-1153, 1991.
2. Anumonwo, J. M. B., H.-Z. Wang, E. Trabka-Janik, B. Dunham, R. D. Veenstra, M. Delmar, and J. Jalife. Gap junctional channels in adult mammalian sinus nodal cells: immunolocalization and electrophysiology. Circ. Res. 71: 229-239, 1992.
3. Beeler, G. W., and H. Reuter. Reconstruction of the action potential of ventricular myocardial fibres. J. Physiol. Lond. 268: 177-210, 1977.
4. Bukauskas, F. F., and R. Weingart. Temperature dependence of gap junction properties in neonatal rat heart cells. Pfluegers Arch. 423: 133-139, 1993.
5. Cai, D., R. L. Winslow, and D. Noble. Effects of gap junction conductance on dynamics of sinoatrial node cells: two-cell and large-scale networks. IEEE Trans. Biomed. Eng. 41: 217-231, 1994.
6. Clapham, D. E., A. Shrier, and R. L. DeHaan. Junctional resistance and action potential delay between embryonic heart cell aggregates. J. Gen. Physiol. 75: 633-654, 1980.
7. DeHaan, R. L. Synchronization of cardiac pacemaker cells by electrical coupling: a study with embryonic heart cell aggregates and pacemaker cell models. In: Cardiac Rate and Rhythm, edited by L. N. Bouman and H. J. Jongsma. The Hague: Martinus Nijhoff, 1982, p. 323-361.
8. DeHaan, R. L., and R. Hirakow. Synchronization of pulsation rates in isolated cardiac myocytes. Exp. Cell Res. 70: 214-220, 1972.
9. Demir, S. S., J. W. Clark, C. R. Murphey, and W. R. Giles. A mathematical model of a rabbit sinoatrial node cell Am. J. Physiol. 266 (Cell Physiol. 35): C832-C852, 1994.
10. f) to generation of spontaneous activity in rabbit sino-atrial node myocytes. J. Physiol. Lond. 434: 23-40, 1991.
11. f) in cells isolated from the rabbit sino-atrial node. J. Physiol. Lond. 377: 61-88, 1986.
12. Guevara, M. R. Chaotic Cardiac Dynamics (PhD thesis). Montreal, Quebec, Canada: McGill University, 1984.
13. Isenberg, G., and U. Klöckner. Calcium tolerant ventricular myocytes prepared by preincubation in a "KB medium." Pfluegers Arch. 395: 6-18, 1982.
14. Jalife, J. Mutual entrainment and electrical coupling as mechanisms of synchronous firing of rabbit sino-atrial pace-maker cells. J. Physiol. Lond. 356: 221-243, 1984.
15. Jongsma, H. J., M. Masson-Pévet, and L. Tsjernina. The development of beat-rate synchronization of rat myocyte pairs in cell culture. Basic Res. Cardiol. 82: 454-464, 1987.
16. Jongsma, H. J., L. Tsjernina, and J. de Bruijne. The establishment of regular beating in populations of pacemaker heart cells: a study with tissue-cultured rat heart cells. J. Mol. Cell. Cardiol. 15: 123-133, 1983.
17. Joyner, R. W., J. Picone, R. D. Veenstra, and D. Rawling. Propagation through electrically coupled cells: effects of regional changes in membrane properties. Circ. Res. 53: 526-534, 1983.
18. Michaels, D. C., E. P. Matyas, and J. Jalife. Dynamic interactions and mutual synchronization of sinoatrial node pacemaker cells: a mathematical model. Circ. Res. 58: 706-720, 1986.
19. Michaels, D. C., E. P. Matyas, and J. Jalife. Mechanisms of sinoatrial pacemaker synchronization: a new hypothesis. Circ. Res. 61: 704-714, 1987.
20. Nakayama, T., Y. Kurachi, A. Noma, and H. Irisawa. Action potential and membrane currents of single pacemaker cells of the rabbit heart. Pfluegers Arch. 402: 248-257, 1984.
21. Oei, H. I., A. C. G. van Ginneken, H. J. Jongsma, and L. N. Bouman. Mechanisms of impulse generation in isolated cells from the rabbit sinoatrial node. J. Mol. Cell. Cardiol. 21: 1137-1149, 1989.
22. Rae, J., K. Cooper, P. Gates, and M. Watsky. Low access resistance perforated patch recordings using amphotericin B. J. Neurosci. Methods 37: 15-26, 1991.
23. Rook, M. B., H. J. Jongsma, and A. C. G. van Ginneken, Properties of single gap junctional channels between isolated neonatal rat heart cells. Am. J. Physiol. 255 (Heart Circ. Physiol. 24): H770-H782, 1988.
24. Sano, T., T. Sawanobori, and H. Adaniya. Mechanism of rhythm determination among pacemaker cells of the mammalian sinus node. Am. J. Physiol. 235 (Heart Circ. Physiol. 4): H379-H384, 1978.
25. Scott, S. Stimulation Simulations of Young Yet Cultured Beating Hearts (PhD thesis). Buffalo, NY: State Univ. of New York, 1979.
26. Sharp, A. A., L. F. Abbott, and E. Marder. Artificial electrical synapses in oscillatory networks. J. Neurophysiol. 67: 1691-1694, 1992.
27. Sharp, A. A., M. B. O'Neil, L. F. Abbott, and E. Marder. Dynamic clamp: computer-generated conductances in real neurons. J. Neurophysiol. 69: 992-995, 1993.
28. Takens-Kwak, B. R., H. J. Jongsma, M. B. Rook, and A. C. G. van Ginneken. Mechanism of heptanol-induced uncoupling of cardiac gap junctions: a perforated-patch clamp study. Am. J. Physiol. 262 (Cell Physiol. 31): C1531-C1538, 1992.
29. Tan, R. C., and R. W. Joyner. Electrotonic influences on action potentials from isolated ventricular cells. Circ. Res. 67: 1071-1081, 1990.
30. Verheijck, E. E. Pacemaker Currents in the Sino-Atrial Node (PhD thesis). Amsterdam, The Netherlands: Univ. of Amsterdam, 1994.
31. Weingart, R., and P. Maurer. Action potential transfer in cell pairs isolated from adult rat and guinea pig ventricles. Circ. Res. 63: 72-80, 1988.
32. Wilders, R., and H. J. Jongsma. Beating irregularity of single pacemaker cells isolated from the rabbit sinoatrial node. Biophys. J. 65: 2601-2613, 1993.
33. Wilders, R., H. J. Jongsma, and A. C. G. van Ginneken. Pacemaker activity of the rabbit sinoatrial node: a comparison of mathematical models. Biophys. J. 60: 1202-1216, 1991.
34. Wilders, R., R. Kumar, R. W. Joyner, H. J. Jongsma, E. E. Verheijck, D. Golod, A. C. G. van Ginneken, and W. N. Goolsby. Action potential conduction between a ventricular cell model and an isolated ventricular cell. Biophys. J. 70: 281-295, 1996.
35. Ypey, D. L., W. P. M. van Meerwjjk, and R. L. DeHaan. Synchronization of cardiac pacemaker cells by electrical coupling: a study with embryonic heart cell aggregates and pacemaker cell models. In: Cardiac Rate and Rhythm, edited by L. N. Bouman and H. J. Jongsma. The Hague: Martinus Nijhoff, 1982, p. 363-395.
36. Ypey, D. L., W. P. M. van Meerwijk, C. Ince, and G. Groos. Mutual entrainment of two pacemaker cells: a study with an electronic parallel conductance model. J. Theor. Biol. 86: 731-755, 1980.