Impact of whole-body CT screening on the costeffectiveness of CT colonography

Radiology

Volumn 251, Issue 1, 2009, Pages 156-165

  Hassan, Cesare ^a   Pickhardt, Perry J ^b   Laghi, Andrea ^c   Zullo, Angelo ^a   Kim, David H ^b   Iafrate, Franco ^c   Di Giulio, Lorenzo ^d   Morini, Sergio ^a  

^a NUOVO REGINA MARGHERITA HOSPITAL   (Italy)

^b UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^c POLICLINICO UMBERTO I   (Italy)

^d UNIVERSITY OF ROME TOR VERGATA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ABDOMINAL AORTA ANEURYSM; ABDOMINAL CANCER; ADULT; AGED; ARTICLE; CANCER RISK; CARDIOVASCULAR RISK; COHORT ANALYSIS; COLORECTAL CANCER; COMPUTED TOMOGRAPHIC COLONOGRAPHY; CORONARY ARTERY DISEASE; COST EFFECTIVENESS ANALYSIS; HUMAN; LUNG CANCER; MAJOR CLINICAL STUDY; MATHEMATICAL MODEL; PELVIS CANCER; PRIORITY JOURNAL; SCREENING TEST; SENSITIVITY ANALYSIS; SIMULATION; WHOLE BODY CT; COMPUTER ASSISTED TOMOGRAPHY; COMPUTER SIMULATION; COST BENEFIT ANALYSIS; ECONOMICS; HEALTH CARE COST; MASS SCREENING; STATISTICAL MODEL; STATISTICS; THORAX RADIOGRAPHY; UNITED STATES; WHOLE BODY IMAGING;

COLONOGRAPHY, COMPUTED TOMOGRAPHIC; COMPUTER SIMULATION; COST-BENEFIT ANALYSIS; HEALTH CARE COSTS; HUMANS; MASS SCREENING; MODELS, ECONOMIC; RADIOGRAPHY, THORACIC; TOMOGRAPHY, X-RAY COMPUTED; UNITED STATES; WHOLE BODY IMAGING;

EID: 64949153420     PISSN: 00338419     EISSN: 15271315     Source Type: Journal    
DOI: 10.1148/radiol.2511080590     Document Type: Article

References (88)

1. Winawer SJ, Fletcher RH, Miller L, et al. Colorectal cancer screening: clinical guidelines and rationale. Gastroenterology 1997;112:594-642.
2. Fleming C, Whitlock EP, Beil TL, Lederle FA. Screening for abdominal aortic aneurysm: a best-evidence systematic review for the U.S. Preventive Services Task Force. Ann Intern Med 2005;142:203-211.
3. Pickhardt PJ, Hassan C, Laghi A, et al. Is there sufficient MDCT capacity to provide colorectal cancer screening with CT colonography for the US population? AJR Am J Roentgenol 2008;190:1044-1049.
4. Brant-Zawadzki M. CT screening: why I do it. AJR Am J Roentgenol 2002;179:319-326.
5. Beinfeld MT, Wittenberg E, Gazelle GS. Cost-effectiveness of whole-body CT screening. Radiology 2005;234:415-422. (Pubitemid 40139911)
6. Hunink MG, Gazelle GS. CT screening: a trade-off of risks, benefits, and costs. J Clin Invest 2003;111:1612-1619. (Pubitemid 38057740)
7. Pickhardt PJ, Choi JR, Hwang I, et al. Computed tomographic virtual colonoscopy to screen for colorectal neoplasia in asymptomatic adults. N Engl J Med 2003;349:2191-2200.
8. Pickhardt PJ, Taylor AJ, Kim DH, Reichelderfer M, Gopal DV, Pfau PR. Screening for colorectal neoplasia with CT colonography: initial experience from the first year of coverage by third-party payers. Radiology 2006;241:417-425. (Pubitemid 44632887)
9. Kim DH, Pickhardt PJ, Taylor AJ, et al. CT colonography versus colonoscopy for the detection of advanced neoplasia. N Engl J Med 2007;357:1403-1412.
10. Levin B, Lieberman DA, McFarland B, et al. Screening and surveillance for the early detection of colorectal cancer and adenomatous polyps, 2008: a joint guideline from the American Cancer Society, the US Multi-Society Task Force on Colorectal Cancer, and the American College of Radiology. Gastroenterology 2008;134:1570-1595.
11. Hassan C, Pickhardt PJ, Laghi A, et al. CT colonography to screen for colorectal cancer, extracolonic cancer, and aortic aneurysm: model simulation with cost-effectiveness analysis. Arch Intern Med 2008;168:696-705.
12. Marshall D, Simpson KN, Earle CC, Chu CW. Economic decision analysis model of screening for lung cancer. Eur J Cancer 2001;37:1759-1767. (Pubitemid 32817050)
13. Mahadevia PJ, Fleisher LA, Frick KD, Eng J, Goodman SN, Powe NR. Lung cancer screening with helical computed tomography in older adult smokers. JAMA 2003;289:313-322.
14. U.S. Census Bureau. International Data Base. U.S. Census Bureau web site. http://www.factfinder.census.gov. Accessed June 5, 2008.
15. United States Life Tables, 2004. In: National vital statistics reports. Hyattsville, Md: National Center for Health Statistics, 2008-11120
16. National Center for Health Statistics. National vital statistics report 2004. Centers for Disease Control web site. http://www.cdc.gov. Accessed April 24, 2008.
17. Mulhall BP, Veerappan GR, Jackson JL. Meta-analysis: computed tomographic colonography. Ann Intern Med 2005;142:635-650.
18. Halligan S, Altman DG, Taylor SA, et al. CT colonography in the detection of colorectal polyps and cancer: systematic review, meta-analysis, and proposed minimum data set for study level reporting. Radiology 2005;237:893-904.
19. Pickhardt PJ, Lee AD, McFarland EG, Taylor AJ. Linear polyp measurement at CT colonography: in vitro and in vivo comparison of two-dimensional and three-dimensional displays. Radiology 2005;236:872-878. (Pubitemid 41170850)
20. Wanhainen A, Lundkvist J, Bergqvist D, Bjorck M. Cost-effectiveness of different screening strategies for abdominal aortic aneurysm. J Vasc Surg 2005;41:741-751. (Pubitemid 40693791)
21. Wilmink AB, Quick CR, Hubbard CS, Day NE. Effectiveness and cost of screening for abdominal aortic aneurysm: results of a population screening program. J Vasc Surg 2003;38:72-77. (Pubitemid 41123290)
22. Shepherd J, Cobbe SM, Ford I, et al. Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia. N Engl J Med 1995;333:1301-1307.
23. Brenner DJ, Elliston CD. Estimated radiation risks potentially associated with fullbody CT screening. Radiology 2004;232:735-738. (Pubitemid 39100257)
24. Bureau of Labor Statistics. Consumer price index. U.S. Department of Labor. http://www.bls.gov/cpi/home.htm. Published November, 2007. Accessed December 14, 2007.
25. Bureau of Labor Statistics. National compensation survey. U.S. Department of Labor http://www.bls.gov/ncs/home.htm. Published March, 2007. Accessed April 14, 2007.
26. Heitman SJ, Manns BJ, Hilsden RJ, Fong A, Dean S, Romagnuolo J. Cost-effectiveness of computerized tomographic colonography versus colonoscopy for colorectal cancer screening. CMAJ 2005;173:877-881. (Pubitemid 41505003)
27. Pignone M, Saha S, Hoerger T, Mandelblatt J. Cost-effectiveness analyses of colorectal cancer screening: a systematic review for the U.S. Preventive Services Task Force. Ann Intern Med 2002;137:96-104.
28. Tengs TO, Wallace A. One thousand health-related quality-of-life estimates. Med Care 2000;38:583-637.
29. Groot Koerkamp B, Nikken JJ, Oei EH, Stijnen T, Ginai AZ, Hunink MG. Value of information analysis used to determine the necessity of additional research: MR imaging in acute knee trauma as an example. Radiology 2008;246:420-425.
30. IMV Medical Information Division 2006 CT benchmark report. Des Plaines, Ill: IMV Medical Information Division, 2006.
31. Henschke CI, McCauley DI, Yankelevitz DF, et al. Early Lung Cancer Action Project: overall design and findings from baseline screening. Lancet 1999;354:99-105.
32. Sone S, Li F, Yang ZG, et al. Results of 3-year mass screening programme for lung cancer using mobile low-dose spiral computed tomography scanner. Br J Cancer 2001;84:25-32.
33. Newcomb PA, Storer BE, Morimoto LM, Templeton A, Potter JD. Long-term efficacy of sigmoidoscopy in the reduction of colorectal cancer incidence. J Natl Cancer Inst 2003;95:622-625. (Pubitemid 36553509)
34. Soetikno RM, Kaltenbach T, Rouse RV, et al. Prevalence of nonpolypoid (flat and depressed) colorectal neoplasms in asymptomatic and symptomatic adults. JAMA 2008;299:1027-1035.
35. Winawer SJ, Zauber AG, Ho MN, et al. Prevention of colorectal cancer by colonoscopic polypectomy: The National Polyp Study Workgroup. N Engl J Med 1993;329:1977-1981.
36. Citarda F, Tomaselli G, Capocaccia R, et al. Efficacy in standard clinical practice of colonoscopic polypectomy in reducing colorectal cancer incidence. Gut 2001;48:812-815.
37. DiSario JA, Foutch PG, Mai HD, Pardy K, Manne RK. Prevalence and malignant potential of colorectal polyps in asymptomatic, average- risk men. Am J Gastroenterol 1991;86:941-945.
38. Vatn MH, Stalsberg H. The prevalence of polyps of the large intestine in Oslo: an autopsy study. Cancer 1982;49:819-825. (Pubitemid 12165443)
39. Rickert RR, Auerbach O, Garfinkel L, Hammond EC, Frasca JM. Adenomatous lesions of the large bowel: an autopsy survey. Cancer 1979;43:1847-1857. (Pubitemid 9203736)
40. Arminski TC, McLean MD. Incidence and distribution of adenomatous polyps of the colon and rectum based on 1,000 autopsy examinations. Dis Colon Rectum 1964;7:249-261.
41. Stemmermann GN, Heilbrun LK, Nomura A, Yano K, Hayashi T. Adenomatous polyps and atherosclerosis: an autopsy study of Japanese men in Hawaii. Int J Cancer 1986;38:789-794. (Pubitemid 17228976)
42. Eide TJ. The age-, sex-, and site-specific occurrence of adenomas and carcinomas of the large intestine within a defined population. Scand J Gastroenterol 1986;21:1083-1088. (Pubitemid 17179097)
43. Johnson DA, Gurney MS, Volpe RJ, et al. A prospective study of the prevalence of colonic neoplasms in asymptomatic patients with an age-related risk. Am J Gastroenterol 1990;85:969-974.
44. Yee J, Akerkar GA, Hung RK, Steinauer-Gebauer A, Wall SD, McQuaid KR. Colorectal neoplasia: performance characteristics of CT colonography for detection in 300 patients. Radiology 2001;219:685-692. (Pubitemid 32476258)
45. Williams AR, Balasooriya BA, Day DW. Polyps and cancer of the large bowel: a necropsy study in Liverpool. Gut 1982;23:835-842. (Pubitemid 12018511)
46. Clark JC, Collan Y, Eide TJ, et al. Prevalence of polyps in an autopsy series from areas with varying incidence of large-bowel cancer. Int J Cancer 1985;36:179-186.
47. Koretz RL. Malignant polyps: are they sheep in wolves' clothing? Ann Intern Med 1993;118:63-68.
48. Imperiale TF, Wagner DR, Lin CY, Larkin GN, Rogge JD, Ransohoff DF. Risk of advanced proximal neoplasms in asymptomatic adults according to the distal colorectal findings. N Engl J Med 2000;343:169-174. (Pubitemid 30489213)
49. Lieberman DA, Weiss DG, Bond JH, Ahnen DJ, Garewal H, Chejfec G. Use of colonoscopy to screen asymptomatic adults for colorectal cancer: Veterans Affairs Cooperative Study Group 380. N Engl J Med 2000;343:162-168.
50. Loeve F, Boer R, Zauber AG, et al. National Polyp Study data: evidence for regression of adenomas. Int J Cancer 2004;111:633-639.
51. Hofstad B, Vatn M, Larsen S, Osnes M. Growth of colorectal polyps: redetection and evaluation of unresected polyps for a period of 3 years. Gut 1996;39:449-456. (Pubitemid 26338537)
52. Hoff G, Foerster A, Vatn MH, Sauar J, Larsen S. Epidemiology of polyps in the rectum and colon: recovery and evaluation of unresected polyps 2 years after detection. Scand J Gastroenterol 1986;21:853-862. (Pubitemid 16015074)
53. Ries LA, Kosary CL, Hankey BF, Miller BA, Harras A, Edwards BK, eds. Surveillance Epidemiology and End Results cancer statistics review, 1973-1994: National Institutes of Health publication no. 97-2789. Bethesda, Md: National Institutes of Health, National Cancer Institute, 1997.
54. National Cancer Institute. Surveillance, Epidemiology and End Results program: fast stats. National Institutes of Health. http://seer.cancer.gov/ faststats/. Published November, 2007. Accessed April 24, 2008.
55. Chen CD, Yen MF, Wang WM, Wong JM, Chen TH. A case-cohort study for the disease natural history of adenoma-carcinoma and de novo carcinoma and surveillance of colon and rectum after polypectomy: implication for efficacy of colonoscopy. Br J Cancer 2003;88:1866-1873.
56. Scott RA, Vardulaki KA, Walker NM, Day NE, Duffy SW, Ashton HA. The long-term benefits of a single scan for abdominal aortic aneurysm (AAA) at age 65. Eur J Vasc Endovasc Surg 2001;21:535-540. (Pubitemid 32624588)
57. Vazquez C, Sakalihasan N, D'Harcour JB, Limet R. Routine ultrasound screening for abdominal aortic aneurysm among 65- and 75-year-old men in a city of 200,000 inhabitants. Ann Vasc Surg 1998;12:544-549. (Pubitemid 28522928)
58. Scott RA, Bridgewater SG, Ashton HA. Randomized clinical trial of screening for abdominal aortic aneurysm in women. Br J Surg 2002;89:283-285. (Pubitemid 34227024)
59. Ashton HA, Buxton MJ, Day NE, et al. The Multicentre Aneurysm Screening Study (MASS) into the effect of abdominal aortic aneurysm screening on mortality in men: a randomised controlled trial. Lancet 2002;360:1531-1539. (Pubitemid 35356366)
60. Lindholt JS, Juul S, Fasting H, Henneberg EW. Hospital costs and benefits of screening for abdominal aortic aneurysms: results from a randomised population screening trial. Eur J Vasc Endovasc Surg 2002;23:55-60. (Pubitemid 41079208)
61. Scott RA, Wilson NM, Ashton HA, Kay DN. Influence of screening on the incidence of ruptured abdominal aortic aneurysm: 5-year results of a randomized controlled study. Br J Surg 1995;82:1066-1070.
62. Heart disease and stroke statistics 2007. American Heart Association. http://www.americanheart.org. Published February, 2007. Accessed April 24, 2008.
63. Kurtz AB, Tsimikas JV, Tempany CM, et al. Diagnosis and staging of ovarian cancer: comparative values of Doppler and conventional US, CT, and MR imaging correlated with surgery and histopathologic analysis - report of the Radiology Diagnostic Oncology Group. Radiology 1999;212:19-27.
64. Kreft BP, Muller-Miny H, Sommer T, et al. Diagnostic value of MR imaging in comparison to CT in the detection and differential diagnosis of renal masses: ROC analysis. Eur Radiol 1997;7:542-547. (Pubitemid 127538673)
65. Niederau C, Grendell J. Diagnosis of pancreatic carcinoma: imaging techniques and tumor markers. Pancreas 1992;7:66-86.
66. Miller WJ, Baron RL, Dodd GD 3rd, Federle MP. Malignancies in patients with cirrhosis: CT sensitivity and specificity in 200 consecutive transplant patients. Radiology 1994;193:645-650.
67. Sobue T, Moriyama N, Kaneko M, et al. Screening for lung cancer with low-dose helical computed tomography: anti-lung cancer association project. J Clin Oncol 2002;20:911-919.
68. Department of Health & Human Services. Centers for Medicare & Medicaid services: physician fee schedule look-up. http://www.cms.hhs.gov/ pfslookup. Published September, 2007. Accessed September 15, 2007.
69. Seare S, Speirs L, Bernard SP, Turner K, Neeshan C. Diagnosis-related group guide. Salt Lake City, Utah: Medicode, 1997.
70. Taplin SH, Barlow W, Urban N, et al. Stage, age, comorbidity, and direct costs of colon, prostate, and breast cancer care. J Natl Cancer Inst 1995;87:417-426.
71. Fireman BH, Quesenberry CP, Somkin CP, et al. Cost of care for cancer in a health maintenance organization. Health Care Financ Rev 1997;18:51-76.
72. Brown ML, Riley GF, Potosky AL, Etzioni RD. Obtaining long-term disease specific costs of care: application to Medicare enrolees diagnosed with colorectal cancer. Med Care 1999;37:1249-1259.
73. Lee TY, Korn P, Heller JA, et al. The cost-effectiveness of a "quick-screen" program for abdominal aortic aneurysms. Surgery 2002;132:399-407.
74. Bosch JL, Kaufman JA, Beinfeld MT, Adriaensen ME, Brewster DC, Gazelle GS. Abdominal aortic aneurysms: cost-effectiveness of elective endovascular and open surgical repair. Radiology 2002;225:337-344. (Pubitemid 35239231)
75. Etzioni R, Urban N, Baker M. Estimating the costs attributable to a disease with application to ovarian cancer. J Clin Epidemiol 1996;49:95-103. (Pubitemid 26089555)
76. Shekarriz B, Upadhyay J, Shekarriz H, et al. Comparison of costs and complications of radical and partial nephrectomy for treatment of localized renal cell carcinoma. Urology 2002;59:211-215.
77. Du W, Touchette D, Vaitkevicius VK, Peters WP, Shields AF. Cost analysis of pancreatic carcinoma treatment. Cancer 2000;89:1917-1924.
78. Sarasin FP, Giostra E, Hadengue A. Costeffectiveness of screening for detection of small hepatocellular carcinoma in western patients with Child-Pugh class A cirrhosis. Am J Med 1996;101:422-434. (Pubitemid 26392861)
79. Riley GF, Potosky AL, Lubitz JD, Kessler LG. Medicare payments from diagnosis to death for elderly cancer patients by stage at diagnosis. Med Care 1995;33:828-841.
80. D'Agostino RB Sr, Grundy S, Sullivan LM, Wilson P; CAD Risk Prediction Group. Validation of the Framingham coronary heart disease prediction scores: results of a multiple ethnic groups investigation. JAMA 2001;286:180-187. (Pubitemid 32640849)
81. Brenner H, Arndt V, Sturmer T, Stegmaier C, Ziegler H, Dhom G. Long-lasting reduction of risk of colorectal cancer following screening endoscopy. Br J Cancer 2001;85:972-976. (Pubitemid 33015999)
82. Muller AD, Sonnenberg A. Prevention of colorectal cancer by flexible endoscopy: a case-control study of 32,702 veterans. Ann Intern Med 1995;123:904-910.
83. Sonnenberg A, Delco F, Inadomi JM. Costeffectiveness of colonoscopy in screening for colorectal cancer. Ann Intern Med 2000;133:573-584.
84. Ladabaum U, Song K. Projected national impact of colorectal cancer screening on clinical and economic outcomes and health services demand. Gastroenterology 2005;129:1151-1162. (Pubitemid 41446855)
85. Vijan S, Hwang EW, Hofer TP, Hayward RA. Which colon cancer screening test? a comparison of costs, effectiveness, and compliance. Am J Med 2001;111:593-601. (Pubitemid 34088068)
86. Ness RM, Holmes AM, Klein R, Dittus R. Cost-utility of one-time colonoscopic screening for colorectal cancer at various ages. Am J Gastroenterol 2000;95:1800-1811. (Pubitemid 30485022)
87. Vardulaki KA, Walker NM, Couto E, et al. Late results concerning feasibility and compliance from a randomized trial of ultrasonographic screening for abdominal aortic aneurysm. Br J Surg 2002;89:861-864.
88. Bengtsson H, Bergqvist D, Ekberg O, Ranstam J. Expansion pattern and risk of rupture of abdominal aortic aneurysms that were not operated on. Eur J Surg 1993;159:461-467. (Pubitemid 23299430)