Claudin-1 protein is a major factor involved in the tumorigenesis of colorectal cancer

Anticancer Research

Volumn 29, Issue 3, 2009, Pages 851-858

  Qun, Huo ^a   Kinugasa, Tetsushi ^a   Lin, Wang ^a   Huang, Jian ^a   Jun, Zhao ^a   Shibaguchi, Hirotomo ^a   Kuroki, Motomu ^a   Tanaka, Toshihiro ^a   Yamashita, Yuichi ^a   Nabeshima, Kazuki ^a   Iwasaki, Hiroshi ^a   Kuroki, Masahide ^a  

^a FUKUOKA UNIVERSITY   (Japan)

Author keywords

Claudin; Clinicopathological factor; Colorectal cancer; Marker

Indexed keywords

CARCINOEMBRYONIC ANTIGEN; CLAUDIN 1; MESSENGER RNA; TRYPSIN;

ADENOCARCINOMA; ADULT; AGED; CANCER CELL CULTURE; CANCER PATIENT; CARCINOGENESIS; CELL AGGREGATION; CELL STRAIN T84; CLINICAL ARTICLE; COLON CANCER; COLORECTAL CANCER; CONFERENCE PAPER; CONTROLLED STUDY; FEMALE; GENE OVEREXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; MUCOSA; PATHOPHYSIOLOGY; PREOPERATIVE PERIOD; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SYNTHESIS;

ADENOCARCINOMA; AGED; AGED, 80 AND OVER; BLOTTING, WESTERN; CELL PROLIFERATION; COLON; COLORECTAL NEOPLASMS; FEMALE; HUMANS; IMMUNOENZYME TECHNIQUES; LYMPHATIC METASTASIS; MALE; MEMBRANE PROTEINS; MIDDLE AGED; RECTUM; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TUMOR CELLS, CULTURED;

EID: 64949140964     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (43)

1. Jankowski JA, Bedford FK, Boulton RA et al Alterations in classical cadherins associated with progression in ulcerative and Crohn's colitis. Lab Invest 78: 1155-1167, 1998.
2. Kinugasa T, Sakaguchi T, Gu X et al Claudins regulate the intestinal barrier in response to immune mediators. Gastroenterology 118: 1001-1011, 2000.
3. Mitic LL and Anderson JM: Molecular architecture of tight junctions. Annu Rev Physiol 60: 121-142, 1998.
4. Mitic LL, Van Itallie CM and Anderson JM: Molecular physiology and pathophysiology of tight junctions I. Tight junction structure and function: lessons from mutant animals and proteins. Am J Physiol Gastrointest Liver Physiol 279: G250-254, 2000.
5. North AJ, Bardsley WG, Hyam J et al Molecular map of the desmosomal plaque. J Cell Sci 112(Pt 23): 4325-4336, 1999.
6. Stevenson BR and Keon BH: The tight junction: morphology to molecules. Annu Rev Cell Dev Biol 14: 89-109, 1998.
7. Swisshelm K, Macek R and Kubbies M: Role of claudins in tumorigenesis. Adv Drug Deliv Rev 57: 919-928, 2005.
8. Tsukita S, Furuse M and Itoh M: Multifunctional strands in tight junctions. Nat Rev Mol Cell Biol 2: 285-293, 2001.
9. Furuse M and Tsukita S: Claudins in occluding junctions of humans and flies. Trends Cell Biol 16: 181-188, 2006.
10. Schneeberger EE and Lynch RD: The tight junction: a multifunctional complex. Am J Physiol Cell Physiol 286: C1213- 1228, 2004.
11. Furuse M, Hirase T, Itoh M et al Occludin: a novel integral membrane protein localizing at tight junctions. J Cell Biol 123: 1777-1788, 1993.
12. Saitou M, Fujimoto K, Doi Y et al Occludin- deficient embryonic stem cells can differentiate into polarized epithelial cells bearing tight junctions. J Cell Biol 141: 397-408, 1998.
13. Furuse M, Fujita K, Hiiragi T et al Claudin-1 and -2: novel integral membrane proteins localizing at tight junctions with no sequence similarity to occludin. J Cell Biol 141: 1539-1550, 1998.
14. Tsukita S and Furuse M: Pores in the wall: claudins constitute tight junction strands containing aqueous pores. J Cell Biol 149: 13-16, 2000.
15. Itoh M, Furuse M, Morita K et al Direct binding of three tight junction-associated MAGUKs, ZO-1, ZO-2, and ZO-3, with the COOH termini of claudins. J Cell Biol 147: 1351-1363, 1999.
16. Hamazaki Y, Itoh M, Sasaki H et al Multi -PDZ domain protein 1 (MUPP1) is concentrated at tight junctions through its possible interaction with claudin-1 and junctional adhesion molecule. J Biol Chem 277: 455-461, 2002.
17. Hewitt KJ, Agarwal R and Morin PJ: The claudin gene family: expression in normal and neoplastic tissues. BMC Cancer 6: 186, 2006.
18. Osanai M, Murata M, Nishikiori N et al: Epigenetic silencing of occludin promotes tumorigenic and metastatic properties of cancer cells via modulations of unique sets of apoptosis- associated genes. Cancer Res 66: 9125-9133, 2006.
19. Resnick MB, Konkin T, Routhier J et al: Claudin-1 is a strong prognostic indicator in stage II colonic cancer: a tissue microarray study. Mod Pathol 18: 511-518, 2005.
20. Sanada Y, Oue N, Mitani Y et al: Down-regulation of the claudin-18 gene, identified through serial analysis of gene expression data analysis, in gastric cancer with an intestinal phenotype. J Pathol 208: 633-642, 2006.
21. Cheung ST, Leung KL, Ip YC et al: Claudin-10 expression level is associated with recurrence of primary hepatocellular carcinoma. Clin Cancer Res 11: 551-556, 2005.
22. Howe HL, Wu X, Ries LA et al: Annual report to the nation on the status of cancer, 1975-2003, featuring cancer among U.S. Hispanic/Latino populations. Cancer 107: 1711-1742, 2006.
23. Peto J: Cancer epidemiology in the last century and the next decade. Nature 411: 390-395, 2001.
24. Tobioka H, Isomura H, Kokai Y et al: Polarized distribution of carcinoembryonic antigen is associated with a tight junction molecule in human colorectal adenocarcinoma. J Pathol 198: 207-212, 2002.
25. Kinugasa T, Huo Q, Higashi D et al: Selective up-regulation of claudin-1 and claudin-2 in colorectal cancer. Anticancer Res 27: 3729-3734, 2007.
26. de Oliveira SS, de Oliveira IM, de Souza W et al: Claudins upregulation in human colorectal cancer. FEBS Lett 579: 6179- 6185, 2005.
27. Grone J, Weber B, Staub E et al: Differential expression of genes encoding tight junction proteins in colorectal cancer: frequent dysregulation of claudin-1, -8 and -12. Int J Colorectal Dis 22: 651-659, 2006.
28. Dhawan P, Singh AB, Deane NG et al: Claudin-1 regulates cellular transformation and metastatic behavior in colon cancer. J Clin Invest 115: 1765-1776, 2005.
29. Japanese Society for Cancer of the Colon and Rectum (JSCCR): General Rules for Clinical and Pathological Studies on Cancer of the Colon, Rectum and Anus. 7th Edition. Tokyo, Japan: Kanehara Shuppan, 2006.
30. Kinugasa T, Kuroki M, Yamanaka T et al: Non-proteolytic release of carcinoembryonic antigen from normal human colonic epithelial cells cultured in collagen gel. Int J Cancer 58: 102- 107, 1994.
31. Soler AP, Miller RD, Laughlin KV et al: Increased tight junctional permeability is associated with the development of colon cancer. Carcinogenesis 20: 1425-1431, 1999.
32. Swift JG, Mukherjee TM and Rowland R: Intercellular junctions in hepatocellular carcinoma. J Submicrosc Cytol 15: 799-810, 1983.
33. Mullin JM: Epithelial barriers, compartmentation, and cancer. Sci STKE 216: pe2, 2004.
34. Martin TA and Jiang WG: Tight junctions and their role in cancer metastasis. Histol Histopathol 16: 1183-1195, 2001.
35. Hirohashi S and Kanai Y: Cell adhesion system and human cancer morphogenesis. Cancer Sci 94: 575-581, 2003.
36. Matsuda Y, Semba S, Ueda J et al: Gastric and intestinal claudin expression at the invasive front of gastric carcinoma. Cancer Sci 98: 1014-1019, 2007.
37. Ueda J, Semba S, Chiba H et al: Heterogeneous expression of claudin-4 in human colorectal cancer: decreased claudin-4 expression at the invasive front correlates cancer invasion and metastasis. Pathobiology 74: 32-41, 2007.
38. Michl P, Barth C, Buchholz M et al: Claudin-4 expression decreases invasiveness and metastatic potential of pancreatic cancer. Cancer Res 63: 6265-6271, 2003.
39. Kominsky SL, Argani P, Korz D et al: Loss of the tight junction protein claudin-7 correlates with histological grade in both ductal carcinoma in situ and invasive ductal carcinoma of the breast. Oncogene 22: 2021-2033, 2003.
40. Dorudi S, Sheffield JP, Poulsom R et al: E- cadherin expression in colorectal cancer. An immunocytochemical and in situ hybridization study. Am J Pathol 142: 981-986, 1993.
41. Hollande F, Lee DJ, Choquet A et al: Adherens junctions and tight junctions are regulated via different pathways by progastrin in epithelial cells. J Cell Sci 116: 1187-1197, 2003.
42. Agarwal R, D'Souza T and Morin PJ: Claudin-3 and claudin-4 expression in ovarian epithelial cells enhances invasion and is associated with increased matrix metalloproteinase-2 activity. Cancer Res 65: 7378-7385, 2005.
43. Weinstein RS, Merk FB and Alroy J: The structure and function of intercellular junctions in cancer. Adv Cancer Res 23: 23-89, 1976.