Heteroplasmy level of the mitochondrial tRNALeu(UUR) A3243G mutation in a chinese family is positively associated with earlier age-of-onset and increasing severity of diabetes

Chinese Medical Sciences Journal

Volumn 24, Issue 1, 2009, Pages 20-25

  Zhang, Shi ^a   Tong, An Li ^a   Zhang, Yun ^a   Nie, Min ^a   Li, Yu Xiu ^a   Wang, Heng ^a  

^a PEKING UNION MEDICAL COLLEGE HOSPITAL   (China)

Author keywords

Heteroplasmy; Maternally inherited diabetes and deafness; tRNALeu(UUR) A3243G mutation

Indexed keywords

ACARBOSE; ARGININE; GENOMIC DNA; GUANINE; INSULIN; LEUCINE; MITOCHONDRIAL DNA; MITOCHONDRIAL RNA; TRANSFER RNA;

ADULT; AGED; ARTICLE; CHINESE; CLINICAL ARTICLE; DIABETES MELLITUS; DISEASE SEVERITY; DNA ISOLATION; EXTRACHROMOSOMAL INHERITANCE; FEMALE; GENE AMPLIFICATION; GENE MUTATION; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC VARIABILITY; HETEROPLASMY; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; ONSET AGE; PATHOGENESIS; PEDIGREE ANALYSIS; POLYMERASE CHAIN REACTION;

EID: 64949105223     PISSN: 10019294     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1001-9294(09)60053-5     Document Type: Article

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