Pharmacokinetic modeling of perfluorooctanoic acid during gestation and lactation in the mouse

Reproductive Toxicology

Volumn 27, Issue 3-4, 2009, Pages 373-386

  Rodriguez, Chester E ^a   Setzer, R Woodrow ^a   Barton, Hugh A ^a  

^a U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

Author keywords

Developmental toxicity; Gestation; Lactation; Mice; Modeling; Perfluorooctanoic acid; Pharmacokinetics; Rats

Indexed keywords

PERFLUOROOCTANOIC ACID;

ANALYTIC METHOD; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD LEVEL; COMPARTMENT MODEL; DEVELOPMENTAL TOXICITY; DOSE RESPONSE; FEMALE; HALF LIFE TIME; LACTATION; MATHEMATICAL ANALYSIS; MOUSE; NONHUMAN; PARTITION COEFFICIENT; PERINATAL PERIOD; PLACENTA CIRCULATION; PREGNANCY; PRENATAL PERIOD; PUP (RODENT); RAT; RISK ASSESSMENT; SPECIES DIFFERENCE; TISSUE GROWTH; TOXICITY; TOXICOKINETICS;

ANIMALS; AREA UNDER CURVE; BODY WEIGHT; COMPUTER SIMULATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ENVIRONMENTAL POLLUTANTS; FEMALE; FLUOROCARBONS; GESTATIONAL AGE; HALF-LIFE; LACTATION; METABOLIC CLEARANCE RATE; MICE; MICE, INBRED STRAINS; MODELS, STATISTICAL; OCTANOIC ACIDS; PREDICTIVE VALUE OF TESTS; PREGNANCY;

ANIMALIA; MUS; RATTUS; RODENTIA;

EID: 64949089752     PISSN: 08906238     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.reprotox.2009.02.009     Document Type: Article

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