Ultraviolet B radiation generated platelet-activating factor receptor agonist formation involves EGF-R-mediated reactive oxygen species

Journal of Immunology

Volumn 182, Issue 5, 2009, Pages 2842-2848

  Yao, Yongxue ^a   Wolverton, Jay E ^a   Zhang, Qiwei ^a   Marathe, Gopal K ^b   Al Hassani, Mohammed ^a   Konger, Raymond L ^a   Travers, Jeffrey B ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MYSORE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

1 FLUORO 2,4 DINITROBENZENE; 1 HEXADECYL 2 N 1 HEXADECYL 2 N METHYLCARBAMOYL; ACETYLCYSTEINE; ANTIOXIDANT; ASCORBIC ACID; EPIDERMAL GROWTH FACTOR RECEPTOR; N [4 (3 BROMOANILINO) 6 QUINAZOLINYL]ACRYLAMIDE; REACTIVE OXYGEN METABOLITE; THROMBOCYTE ACTIVATING FACTOR RECEPTOR; THROMBOCYTE ACTIVATING FACTOR RECEPTOR AFFECTING AGENT; UNCLASSIFIED DRUG; FIBRINOGEN RECEPTOR; G PROTEIN COUPLED RECEPTOR; THROMBOCYTE ACTIVATING FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DELAYED HYPERSENSITIVITY; DRUG EFFECT; EPIDERMIS CELL; HUMAN; HUMAN CELL; IMMUNOSUPPRESSIVE TREATMENT; MOUSE; NONHUMAN; PRIORITY JOURNAL; SKIN; SYNTHESIS; ULTRAVIOLET B RADIATION; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CELL STRAIN KB; CONTACT DERMATITIS; DRUG POTENTIATION; EPITHELIUM CELL; HAIRLESS MOUSE; IMMUNOLOGY; METABOLISM; PHYSIOLOGY; RADIATION EXPOSURE; ULTRAVIOLET RADIATION;

ANIMALS; DERMATITIS, CONTACT; EPITHELIAL CELLS; HUMANS; IMMUNOSUPPRESSION; KB CELLS; MICE; MICE, HAIRLESS; MICE, INBRED C57BL; PLATELET ACTIVATING FACTOR; PLATELET MEMBRANE GLYCOPROTEINS; REACTIVE OXYGEN SPECIES; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTORS, G-PROTEIN-COUPLED; SKIN; ULTRAVIOLET RAYS;

EID: 64849110232     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0802689     Document Type: Article

References (46)

1. Boring, C. C., T. S. Squires, and T. Tong. 1992. Cancer statistics, 1992. CA Cancer J. Clin. 42: 19-38.
2. Fisher, G. J., S. C. Datta, H. S. Talwar, Z. Q. Wang, J. Varani, S. Kang, and J. J. Voorhees. 1996. Molecular basis of sun-induced premature skin ageing and retinoid antagonism. Nature 379: 335-339.
3. Kripke, M. L. 1977. Latency, histology, and antigenicity of tumors induced by ultraviolet light in three inbred mouse strains. Cancer Res. 37: 1395-1400.
4. Ullrich, S. E. 2002. Photoimmune suppression and photocarcinogenesis. Front. Biosci. 7: d684-d703.
5. Ullrich, S. E. 2005. Mechanisms underlying UV-induced immune suppression. Mutat. Res. 571: 185-205.
6. Fisher, M. S., and M. L. Kripke. 1982. Suppressor T lymphocytes control the development of primary skin cancers in ultraviolet-irradiated mice. Science 216: 1133-1134.
7. Noonan, F. P., E. C. De Fabo, and M. L. Kripke. 1981. Suppression of contact hypersensitivity by ultraviolet radiation: an experimental model. Springer Semin. Immunopathol. 4: 293-304.
8. Prescott, S. M., G. A. Zimmerman, D. M. Stafforini, and T. M. McIntyre. 2000. Platelet-activating factor and related lipid mediators. Annu. Rev. Biochem. 69: 419-445.
9. Izumi, T., and T. Shimizu. 1995. Platelet-activating factor receptor: gene expression and signal transduction. Biochim. Biophys. Acta 1259: 317-333.
10. Travers, J. B., K. A. Harrison, C. A. Johnson, K. L. Clay, and J. G. Morelli. 1996. Platelet-activating factor biosynthesis induced by various stimuli in human Ha-CaT keratinocytes. J. Invest. Dermatol. 107: 88-94.
11. Marathe, G. K., K. A. Harrison, R. C. Murphy, S. M. Prescott, G. A. Zimmerman, and T. M. McIntyre. 2000. Bioactive phospholipid oxidation products. Free Radical Biol. Med. 28: 1762-1770.
12. Stafforini, D. M., T. M. McIntyre, G. A. Zimmerman, and S. M. Prescott. 1997. Platelet-activating factor acetylhydrolases. J. Biol. Chem. 272: 17895-17898.
13. Zhang, Q., Y. Yao, R. L. Konger, A. L. Sinn, S. Cai, K. E. Pollok, and J. B. Travers. 2008. UVB radiation-mediated inhibition of contact hypersensitivity reactions is dependent on the platelet-activating factor system. J. Invest. Dermatol. 128: 1780-1787.
14. Marathe, G. K., C. Johnson, S. D. Billings, M. D. Southall, Y. Pei, D. Spandau, R. C. Murphy, G. A. Zimmerman, T. M. McIntyre, and J. B. Travers. 2005. Ultraviolet B radiation generates platelet-activating factor-like phospholipids underlying cutaneous damage. J. Biol. Chem. 280: 35448-35457.
15. Pei, Y., L. A. Barber, R. C. Murphy, C. A. Johnson, S. W. Kelley, L. C. Dy, R. H. Fertel, T. M. Nguyen, D. A. Williams, and J. B. Travers. 1998. Activation of the epidermal platelet-activating factor receptor results in cytokine and cyclo-oxygenase-2 biosynthesis. J. Immunol. 161: 1954-1961.
16. Barber, L. A., D. F. Spandau, S. C. Rathman, R. C. Murphy, C. A. Johnson, S. W. Kelley, S. A. Hurwitz, and J. B. Travers. 1998. Expression of the platelet-activating factor receptor results in enhanced ultraviolet B radiation-induced apoptosis in a human epidermal cell line. J. Biol. Chem. 273: 18891-18897.
17. Travers, J. B., H. J. Edenberg, Q. Zhang, M. Al-Hassani, Q. Yi, S. Baskaran, and R. L. Konger. 2008. Augmentation of UVB radiation-mediated early gene expression by the epidermal platelet-activating factor receptor. J. Invest. Dermatol. 128: 455-460.
18. Walterscheid, J. P., S. E. Ullrich, and D. X. Nghiem. 2002. Platelet-activating factor, a molecular sensor for cellular damage, activates systemic immune suppression. J. Exp. Med. 195: 171-179.
19. Alappatt, C., C. A. Johnson, K. L. Clay, and J. B. Travers. 2000. Acute keratinocyte damage stimulates platelet-activating factor production. Arch. Dermatol. Res. 292: 256-259.
20. Wolf, P., D. X. Nghiem, J. P. Walterscheid, S. Byrne, Y. Matsumura, Y. Matsumura, C. Bucana, H. N. Ananthaswamy, and S. E. Ullrich. 2006. Platelet-activating factor is crucial in psoralen and ultraviolet A-induced immune suppression, inflammation, and apoptosis. Am. J. Pathol. 169: 795-805.
21. Zhang, Q., N. Mousdicas, Q. Yi, M. Al-Hassani, S. D. Billings, S. M. Perkins, K. M. Howard, S. Ishii, T. Shimizu, and J. B. Travers. 2005. Staphylococcal lipoteichoic acid inhibits delayed-type hypersensitivity reactions via the platelet-activating factor receptor. J. Clin. Invest. 115: 2855-2861.
22. Kulms, D., and T. Schwarz. 2002. Independent contribution of three different pathways to ultraviolet-B-induced apoptosis. Biochem. Pharmacol. 64: 837-841.
23. Peus, D., R. A. Vasa, A. Meves, M. Pott, A. Beyerle, K. Squillace, and M. R. Pittelkow. 1998. H2O2 is an important mediator of UVB-induced EGF-receptor phosphorylation in cultured keratinocytes. J. Invest. Dermatol. 110: 966-971.
24. Herrlich, P., and F. D. Bohmer. 2000. Redox regulation of signal transduction in mammalian cells. Biochem. Pharmacol. 59: 35-41.
25. Wan, Y., Z. Wang, Y. Shao, Y. Xu, J. Voorhees, and G. Fisher. 2000. UV-induced expression of GADD45 is mediated by an oxidant sensitive pathway in cultured human keratinocytes and in human skin in vivo. Int. J. Mol. Med. 6: 683-688.
26. Nakamura, T., S. R. Pinnell, D. Darr, I. Kurimoto, S. Itami, K. Yoshikawa, and J. W. Streilein. 1997. Vitamin C abrogates the deleterious effects of UVB radiation on cutaneous immunity by a mechanism that does not depend on TNF-α. J. Invest. Dermatol. 109: 20-24.
27. Steenvoorden, D. P., and G. Beijersbergen van Henegouwen. 1999. Protection against UV-induced systemic immunosuppression in mice by a single topical application of the antioxidant vitamins C and E. Int. J. Radiat. Biol. 75: 747-755.
28. Steenvoorden, D. P., and G. M. Beijersburgen van Henegouwen. 1998. Glutathione synthesis is not involved in protection by N-acetylcysteine against UVB-induced systemic immunosuppression in mice. Photochem. Photobiol. 68: 97-100.
29. Mascia, F., V. Mariani, G. Girolomoni, and S. Pastore. 2003. Blockade of the EGF receptor induces a deranged chemokine expression in keratinocytes leading to enhanced skin inflammation. Am. J. Pathol. 163: 303-312.
30. Bligh, E. G., and W. J. Dyer. 1959. A rapid method of total lipid extraction and purification. Can. J. Biochem. Physiol. 37: 911-917.
31. Travers, J. B., J. C. Huff, M. Rola-Pleszczynski, E. W. Gelfand, J. G. Morelli, and R. C. Murphy. 1995. Identification of functional platelet-activating factor receptors on human keratinocytes. J. Invest. Dermatol. 105: 816-823.
32. 2+ channels in human B lymphocytes. Cell 54: 229-234.
33. Lehr, H. A., A. S. Weyrich, R. K. Saetzler, A. Jurek, K. E. Arfors, G. A. Zimmerman, S. M. Prescott, and T. M. McIntyre. 1997. Vitamin C blocks inflammatory platelet-activating factor mimetics created by cigarette smoking. J. Clin. Invest. 99: 2358-2364.
34. Wang, H., and J. A. Joseph. 1999. Quantifying cellular oxidative stress by dichlorofluorescein assay using microplate reader. Free Radical Biol. Med. 27: 612-616.
35. Petersen, J. E., T. S. Hiran, W. S. Goebel, C. Johnson, R. C. Murphy, F. H. Azmi, A. F. Hood, J. B. Travers, and M. C. Dinauer. 2002. Enhanced cutaneous inflammatory reactions to Aspergillus fumigatus in a murine model of chronic granulomatous disease. J. Invest. Dermatol. 118: 424-429.
36. Rockel, N., C. Esser, S. Grether-Beck, U. Warskulat, U. Flogel, A. Schwarz, T. Schwarz, D. Yarosh, D. Haussinger, and J. Krutmann. 2007. The osmolyte taurine protects against ultraviolet B radiation-induced immunosuppression. J. Immunol. 179: 3604-3612.
37. Matsumura, Y., S. N. Byrne, D. X. Nghiem, Y. Miyahara, and S. E. Ullrich. 2006. A role for inflammatory mediators in the induction of immunoregulatory B cells. J. Immunol. 177: 4810-4817.
38. Aruoma, O. I., B. Halliwell, B. M. Hoey, and J. Butler. 1989. The antioxidant action of N-acetylcysteine: its reaction with hydrogen peroxide, hydroxyl radical, superoxide, and hypochlorous acid. Free Radical Biol. Med. 6: 593-597.
39. Halvey, P. J., W. H. Watson, J. M. Hansen, Y. M. Go, A. Samali, and D. P. Jones. 2005. Compartmental oxidation of thiol-disulphide redox couples during epidermal growth factor signalling. Biochem. J. 386: 215-219.
40. Bertling, C. J., F. Lin, and A. W. Girotti. 1996. Role of hydrogen peroxide in the cytotoxic effects of UVA/B radiation on mammalian cells. Photochem. Photobiol. 64: 137-142.
41. Wang, H. Q., T. Quan, T. He, T. F. Franke, J. J. Voorhees, and G. J. Fisher. 2003. Epidermal growth factor receptor-dependent, NF-κB- independent activation of the phosphatidylinositol 3-kinase/Akt pathway inhibits ultraviolet irradiation-induced caspases-3, -8, and -9 in human keratinocytes. J. Biol. Chem. 278: 45737-45745.
42. Xu, Y., Y. Shao, J. J. Voorhees, and G. J. Fisher. 2006. Oxidative inhibition of receptor-type protein-tyrosine phosphatase κ by ultraviolet irradiation activates epidermal growth factor receptor in human keratinocytes. J. Biol. Chem. 281: 27389-27397.
43. Sreevidya, C. S., N. M. Khaskhely, A. Fukunaga, P. Khaskina, and S. E. Ullrich. 2008. Inhibition of photocarcinogenesis by platelet-activating factor or serotonin receptor antagonists. Cancer Res. 68: 3978-3984.
44. Frankel, E. N. 1984. Chemistry of free radical and singlet oxidation of lipids. Prog. Lipid Res. 23: 197-221.
45. Heery, J. M., M. Kozak, D. M. Stafforini, D. A. Jones, G. A. Zimmerman, T. M. McIntyre, and S. M. Prescott. 1995. Oxidatively modified LDL contains phospholipids with platelet-activating factor-like activity and stimulates the growth of smooth muscle cells. J. Clin. Invest. 96: 2322-2330.
46. Schade, N., C. Esser, and J. Krutmann. 2005. Ultraviolet B radiation-induced immunosuppression: molecular mechanisms and cellular alterations. Photochem. Photobiol. Sci. 4: 699-708.