-
1
-
-
0025067462
-
Molecular genetics of the P-450 superfamily
-
Gonzalez FJ. Molecular genetics of the P-450 superfamily. Pharmac Ther. 1990;45:1-38.
-
(1990)
Pharmac Ther
, vol.45
, pp. 1-38
-
-
Gonzalez, F.J.1
-
2
-
-
0029025655
-
Recent advances: The cytochrome P450 enzymes
-
Slaughter RL, Edwards DJ. Recent advances: the cytochrome P450 enzymes. Ann Pharmacother. 1995;29: 619-624.
-
(1995)
Ann Pharmacother
, vol.29
, pp. 619-624
-
-
Slaughter, R.L.1
Edwards, D.J.2
-
3
-
-
0020434524
-
Purification and characterization of liver microsomal cytochrome P450: Electrophoretic, spectral, catalytic and immunochemical properties and inducibility of eight isozymes isolated from rats treated with phenobarbital or B-naphthoflavone
-
Guengerich FP, Dannan GA, Wright ST, et al. Purification and characterization of liver microsomal cytochrome P450: electrophoretic, spectral, catalytic and immunochemical properties and inducibility of eight isozymes isolated from rats treated with phenobarbital or B-naphthoflavone. Biochemistry. 1982;21:6019-6030.
-
(1982)
Biochemistry
, vol.21
, pp. 6019-6030
-
-
Guengerich, F.P.1
Dannan, G.A.2
Wright, S.T.3
-
4
-
-
0020374942
-
Phenobarbital-induced rat liver cytochrome P-450-purification and characterization of two closely related isozymic forms
-
Waxman DJ, Walsh C. Phenobarbital-induced rat liver cytochrome P-450-purification and characterization of two closely related isozymic forms. J Biol Chem. 1982;2257: 10446-10457.
-
(1982)
J Biol Chem
, vol.2257
, pp. 10446-10457
-
-
Waxman, D.J.1
Walsh, C.2
-
5
-
-
84869266326
-
-
P450 tables. Available at: March 25, 2007
-
P450 tables. Available at: http://medicine.iupui.edu/flockhart/table.htm Accessed March 25, 2007.
-
-
-
-
6
-
-
0026575955
-
The mechanism of the interaction between amiodarone and warfarin in humans
-
Heimark LD, Wienkers L, Dunze K, et al. The mechanism of the interaction between amiodarone and warfarin in humans. Clin Pharmacol Ther. 1992;51:398-407.
-
(1992)
Clin Pharmacol Ther
, vol.51
, pp. 398-407
-
-
Heimark, L.D.1
Wienkers, L.2
Dunze, K.3
-
7
-
-
0031892332
-
Effects of erythromycin or rifampin on losartan pharmacokinetics in healthy volunteers
-
Williamson KM, Patterson JH, McQueen RH, et al. Effects of erythromycin or rifampin on losartan pharmacokinetics in healthy volunteers. Clin Pharmacol Ther. 1998;63: 316-323.
-
(1998)
Clin Pharmacol Ther
, vol.63
, pp. 316-323
-
-
Williamson, K.M.1
Patterson, J.H.2
McQueen, R.H.3
-
8
-
-
0030724427
-
Effect of fluconazole on the pharmacokinetics of eprosartan and losartan in healthy male volunteers
-
Kazierad DJ, Martin DE, Blum RA, et al. Effect of fluconazole on the pharmacokinetics of eprosartan and losartan in healthy male volunteers. Clin Pharmacol Ther. 1997;62:417-425.
-
(1997)
Clin Pharmacol Ther
, vol.62
, pp. 417-425
-
-
Kazierad, D.J.1
Martin, D.E.2
Blum, R.A.3
-
9
-
-
0029025655
-
Recent advances: The cytochrome P450 enzymes
-
Slaughter RL, Edwards DJ. Recent advances: the cytochrome P450 enzymes. Ann Pharmacother. 1995;29:619-624.
-
(1995)
Ann Pharmacother
, vol.29
, pp. 619-624
-
-
Slaughter, R.L.1
Edwards, D.J.2
-
10
-
-
0026680545
-
Clinical relevance of cimetidine drug interctions
-
Shinn AF. Clinical relevance of cimetidine drug interctions. Drug Saf. 1992;7;245-67.
-
(1992)
Drug Saf
, vol.7
, pp. 245-267
-
-
Shinn, A.F.1
-
11
-
-
0028787051
-
Cytochrome P450 isoenzyme and antiepileptic drug interactions
-
Levy RH. Cytochrome P450 isoenzyme and antiepileptic drug interactions. Epilepsia. 1995;36(Suppl 5):S8-S13.
-
(1995)
Epilepsia
, vol.36
, Issue.SUPPL. 5
-
-
Levy, R.H.1
-
12
-
-
0026531077
-
Pharmacokinetic drug interactions with rifampin
-
Venkatesan K. Pharmacokinetic drug interactions with rifampin. Clin Pharmacokinet. 1992;22:47-65.
-
(1992)
Clin Pharmacokinet
, vol.22
, pp. 47-65
-
-
Venkatesan, K.1
-
13
-
-
0028876653
-
Possible inhibition of hepatic metabolism of quinidine by erythromycin
-
Spinier S, Cheng JWM, Kindwall KE, et al. Possible inhibition of hepatic metabolism of quinidine by erythromycin. Clin Pharmacol Ther. 1995;57:89-94.
-
(1995)
Clin Pharmacol Ther
, vol.57
, pp. 89-94
-
-
Spinier, S.1
Cheng, J.W.M.2
Kindwall, K.E.3
-
14
-
-
0025675909
-
Effect of phenytoin on the clinical pharmacokinetics of amiodarone
-
Nolan PE Jr, Marcus FL, Karol MD, et al. Effect of phenytoin on the clinical pharmacokinetics of amiodarone. J Clin Pharmacol. 1990;30:1112-1119.
-
(1990)
J Clin Pharmacol
, vol.30
, pp. 1112-1119
-
-
Nolan Jr, P.E.1
Marcus, F.L.2
Karol, M.D.3
-
16
-
-
0020514651
-
Drug interactions with amiodarone
-
Marcus FI. Drug interactions with amiodarone. Am Heart J. 1983;106:924-930.
-
(1983)
Am Heart J
, vol.106
, pp. 924-930
-
-
Marcus, F.I.1
-
17
-
-
0021183323
-
Effect of amiodarone on serum quinidine and procainamide levels
-
Saal AK, Werner JA, Greene HL, et al. Effect of amiodarone on serum quinidine and procainamide levels. Am J Cardiol. 1984;53:1264-1267.
-
(1984)
Am J Cardiol
, vol.53
, pp. 1264-1267
-
-
Saal, A.K.1
Werner, J.A.2
Greene, H.L.3
-
18
-
-
0031450583
-
Awareness of potential drug interactions may aid avoidance
-
DeVane CL, Gill HS, Markowitz JS, et al. Awareness of potential drug interactions may aid avoidance. Ther Drug Monit. 1997;19:366-367.
-
(1997)
Ther Drug Monit
, vol.19
, pp. 366-367
-
-
DeVane, C.L.1
Gill, H.S.2
Markowitz, J.S.3
-
19
-
-
0033678468
-
Identification and biological activity of the active metabolite of clopidogrel
-
Savi P, Pereillo JM, Uzabiaga MF, et al. Identification and biological activity of the active metabolite of clopidogrel. Throm. Haemost. 2000;84:891-896.
-
(2000)
Throm. Haemost
, vol.84
, pp. 891-896
-
-
Savi, P.1
Pereillo, J.M.2
Uzabiaga, M.F.3
-
20
-
-
24944503641
-
Stereoselective inhibition of human platelet aggregation by R-l38727, the active metabolite of CS-747 (prasugrel, LY640315), a novel P2Y12 receptor inhibitor
-
Hasegawa M, Sugidachi A, Ogawa T, et al. Stereoselective inhibition of human platelet aggregation by R-l38727, the active metabolite of CS-747 (prasugrel, LY640315), a novel P2Y12 receptor inhibitor. Thromb Haemost. 2005;94: 593-598.
-
(2005)
Thromb Haemost
, vol.94
, pp. 593-598
-
-
Hasegawa, M.1
Sugidachi, A.2
Ogawa, T.3
-
21
-
-
0037707248
-
Mechanism of production of pharmacologically active metabolites of CS-747, a new pro-drug ADP-receptor antagonist
-
Kazui M, Ishizuka T, Yamamura N, et al. Mechanism of production of pharmacologically active metabolites of CS-747, a new pro-drug ADP-receptor antagonist. Thromb Haemost. 2001;12(Suppl):P1916.
-
(2001)
Thromb Haemost
, vol.12
, Issue.SUPPL.
-
-
Kazui, M.1
Ishizuka, T.2
Yamamura, N.3
-
22
-
-
64549110134
-
-
Lau C, L. Waskell LA, Carville D, et al. The antiplatelet activity of clopidogrel is inhibited by atorvastatin but not by pravastatin. Circulation. 2000;102:2086.
-
Lau C, L. Waskell LA, Carville D, et al. The antiplatelet activity of clopidogrel is inhibited by atorvastatin but not by pravastatin. Circulation. 2000;102:2086.
-
-
-
-
23
-
-
0037422534
-
Atorvastatin reduces the ability of clopidogrel to inhibit platelet aggregation: A new drug-drug interaction
-
Lau C, Waskell LA, Watkins PB, et al. Atorvastatin reduces the ability of clopidogrel to inhibit platelet aggregation: a new drug-drug interaction. Circulation. 2003;107:32-37.
-
(2003)
Circulation
, vol.107
, pp. 32-37
-
-
Lau, C.1
Waskell, L.A.2
Watkins, P.B.3
-
24
-
-
0033503513
-
Effects of CYP3A inhibition on the metabolism of cilostazil
-
Suri A, Forbes WP, Bramer SL. Effects of CYP3A inhibition on the metabolism of cilostazil. Clin Pharma-cokinet. 1999;37(Suppl 2):61-68.
-
(1999)
Clin Pharma-cokinet
, vol.37
, Issue.SUPPL. 2
, pp. 61-68
-
-
Suri, A.1
Forbes, W.P.2
Bramer, S.L.3
-
25
-
-
0023923975
-
Drug interactions in hypertension
-
ll:II-l-II-3
-
Wood AJ. Drug interactions in hypertension. Hypertension. 1988;ll:II-l-II-3.
-
(1988)
Hypertension
-
-
Wood, A.J.1
-
27
-
-
0033670208
-
Drug interaction between cimetidine and timolol ophthalmic solution: Effect on heart rate and intraocular pressure in healthy Japanese volunteers
-
Ishii Y, Nakamura K, Tsutsumi K, et al. Drug interaction between cimetidine and timolol ophthalmic solution: effect on heart rate and intraocular pressure in healthy Japanese volunteers. J Clin Pharmacol. 2000;40: 193-199.
-
(2000)
J Clin Pharmacol
, vol.40
, pp. 193-199
-
-
Ishii, Y.1
Nakamura, K.2
Tsutsumi, K.3
-
28
-
-
0028809608
-
Pharmacogenetic explanation for excessive beta-blockade following timolol eye drops: Potential for oral-ophthalmic drug interaction
-
Edeki TI, He H, Wood AJ. Pharmacogenetic explanation for excessive beta-blockade following timolol eye drops: potential for oral-ophthalmic drug interaction. JAMA. 1995;274:1611-1613.
-
(1995)
JAMA
, vol.274
, pp. 1611-1613
-
-
Edeki, T.I.1
He, H.2
Wood, A.J.3
-
29
-
-
0028973416
-
The fate of naringin in humans: A key to grapefruit juice-drug interactions
-
Fuhr U, Dummert AL. The fate of naringin in humans: a key to grapefruit juice-drug interactions. Clin Pharmacol Ther. 1995;58:364-373.
-
(1995)
Clin Pharmacol Ther
, vol.58
, pp. 364-373
-
-
Fuhr, U.1
Dummert, A.L.2
-
30
-
-
0029133833
-
Grapefruit juice interactions with drugs
-
Abramowicz M, ed
-
Abramowicz M, ed. Grapefruit juice interactions with drugs. Med Lett. 1995;37:63-64.
-
(1995)
Med Lett
, vol.37
, pp. 63-64
-
-
-
31
-
-
0025944230
-
Erythromycin-felodipine interaction [Letter]
-
Nordine LH. Erythromycin-felodipine interaction [Letter]. Drug Intell Clin Pharm. 1991;25:1007-1008.
-
(1991)
Drug Intell Clin Pharm
, vol.25
, pp. 1007-1008
-
-
Nordine, L.H.1
-
32
-
-
0030898365
-
Itraconazole greatly increases plasma concentrations and effects of felodipine
-
Jalava KM, Olkkola KT, Neuvonen PJ. Itraconazole greatly increases plasma concentrations and effects of felodipine. Clin Pharmacol Ther. 1997;61:410-415.
-
(1997)
Clin Pharmacol Ther
, vol.61
, pp. 410-415
-
-
Jalava, K.M.1
Olkkola, K.T.2
Neuvonen, P.J.3
-
33
-
-
0023204413
-
Ranitidine and cimetidine drug interactions with single dose and steady-state nifedipine administration
-
Smith SR, Kendall MJ, Lobo J, et al. Ranitidine and cimetidine drug interactions with single dose and steady-state nifedipine administration. Br J Clin Pharmacol. 1987; 23:311-315.
-
(1987)
Br J Clin Pharmacol
, vol.23
, pp. 311-315
-
-
Smith, S.R.1
Kendall, M.J.2
Lobo, J.3
-
34
-
-
0023889182
-
Effect of cimetidine or ranitidine administration on nifedipine pharmacokinetics and pharmacodynamics
-
Schwartz JB, Upton RA, Lin ET, et al. Effect of cimetidine or ranitidine administration on nifedipine pharmacokinetics and pharmacodynamics. Clin Pharmacol Ther. 1988;43: 673-680.
-
(1988)
Clin Pharmacol Ther
, vol.43
, pp. 673-680
-
-
Schwartz, J.B.1
Upton, R.A.2
Lin, E.T.3
-
35
-
-
0029786432
-
Differential induction of prehepatic and hepatic metabolism of verapamil by rifampin
-
Fromm MF, Busse D, Kroemer HK, et al. Differential induction of prehepatic and hepatic metabolism of verapamil by rifampin. Hepatology. 1996;24:796-801.
-
(1996)
Hepatology
, vol.24
, pp. 796-801
-
-
Fromm, M.F.1
Busse, D.2
Kroemer, H.K.3
-
36
-
-
0027302305
-
The use of in vitro metabolism studies in the understanding of new drugs
-
Chiu SH. The use of in vitro metabolism studies in the understanding of new drugs. J Pharmacol Toxicol Methods. 1993;29:77-83.
-
(1993)
J Pharmacol Toxicol Methods
, vol.29
, pp. 77-83
-
-
Chiu, S.H.1
-
37
-
-
0032773854
-
Diltiazem inhibition of cytochrome P-450 3A activity is due to metabolite intermediate complex formation
-
Jones DR, Gorski JC, Hamman MA, et al. Diltiazem inhibition of cytochrome P-450 3A activity is due to metabolite intermediate complex formation. J Pharmacol Exp Ther. 1999;290:1116-1125.
-
(1999)
J Pharmacol Exp Ther
, vol.290
, pp. 1116-1125
-
-
Jones, D.R.1
Gorski, J.C.2
Hamman, M.A.3
-
38
-
-
0030665572
-
Diltiazem-cyclosporin pharmacokinetic interaction: Dose-response relationship
-
Jones TE, Morris RG, Mathew TH. Diltiazem-cyclosporin pharmacokinetic interaction: dose-response relationship. Br J Clin Pharmacol. 1997;44:499-504.
-
(1997)
Br J Clin Pharmacol
, vol.44
, pp. 499-504
-
-
Jones, T.E.1
Morris, R.G.2
Mathew, T.H.3
-
39
-
-
0030042485
-
Clinically significant drug interactions with cyclosporin: An update
-
Campana C, Regazzi MB, Buggia I, et al. Clinically significant drug interactions with cyclosporin: an update. Clin Pharmacokinet. 1996;30:141-179.
-
(1996)
Clin Pharmacokinet
, vol.30
, pp. 141-179
-
-
Campana, C.1
Regazzi, M.B.2
Buggia, I.3
-
40
-
-
0031670167
-
Erythromycin and verapamil considerably increase serum simvastatin and simvastatin acid concentrations
-
Kantola T, Kivisto KT, Neuvonen PJ. Erythromycin and verapamil considerably increase serum simvastatin and simvastatin acid concentrations. Clin Pharmacol Ther. 1998;64:177-182.
-
(1998)
Clin Pharmacol Ther
, vol.64
, pp. 177-182
-
-
Kantola, T.1
Kivisto, K.T.2
Neuvonen, P.J.3
-
41
-
-
79955454841
-
-
Available at:, Accessed April 24, 2007
-
Zocor prescribing information. Available at: http://www.zocor.com/zocor/ shared/documents/english/pi.pdf. Accessed April 24, 2007.
-
Zocor prescribing information
-
-
-
42
-
-
0032886788
-
Concomitant use of cytochrome P450 3A4 inhibitors and simvastatin
-
Gruer PJ, Vega JM, Mercuri MF, et al. Concomitant use of cytochrome P450 3A4 inhibitors and simvastatin. Am J Cardiol. 1999;84:811-815.
-
(1999)
Am J Cardiol
, vol.84
, pp. 811-815
-
-
Gruer, P.J.1
Vega, J.M.2
Mercuri, M.F.3
-
43
-
-
0029925714
-
Diltiazem enhances the effects of triazolam by inhibiting its metabolism
-
Varhe A, Olkkola KT, Neuvonen PJ. Diltiazem enhances the effects of triazolam by inhibiting its metabolism. Clin Pharmacol Ther. 1996;59:369-375.
-
(1996)
Clin Pharmacol Ther
, vol.59
, pp. 369-375
-
-
Varhe, A.1
Olkkola, K.T.2
Neuvonen, P.J.3
-
44
-
-
0030444880
-
Effect of diltiazem on midazolam and alfentanil disposition in patients undergoing coronary artery bypass grafting
-
Ahonen J, Olkkola KT, Salmenpera M, et al. Effect of diltiazem on midazolam and alfentanil disposition in patients undergoing coronary artery bypass grafting. Anesthesiology. 1996;85:1246-1252.
-
(1996)
Anesthesiology
, vol.85
, pp. 1246-1252
-
-
Ahonen, J.1
Olkkola, K.T.2
Salmenpera, M.3
-
45
-
-
0034082667
-
Diltiazem and mibefradil increase the plasma concentrations and greatly enhance the adrenal-suppressant effect of oral methyl-prednisolone
-
Varis T, Backman JT, Kivisto KT, et al. Diltiazem and mibefradil increase the plasma concentrations and greatly enhance the adrenal-suppressant effect of oral methyl-prednisolone. Clin Pharmacol Ther. 2000;67:215-221.
-
(2000)
Clin Pharmacol Ther
, vol.67
, pp. 215-221
-
-
Varis, T.1
Backman, J.T.2
Kivisto, K.T.3
-
46
-
-
1842779162
-
Prediction of in vivo drug interactions with eplerenone in man from in vitro metabolic inhibition data
-
Cook CS, Berry LM. Burton E. Prediction of in vivo drug interactions with eplerenone in man from in vitro metabolic inhibition data. Xenobiotica. 2004;34:215-228.
-
(2004)
Xenobiotica
, vol.34
, pp. 215-228
-
-
Cook, C.S.1
Berry, L.M.2
Burton, E.3
-
47
-
-
0026088892
-
Expanded clinical evaluation of lovastatin (EXCEL) study results. 1. Efficacy in modifying plasma lipoproteins and adverse event profile in modifying plasma lipoproteins and adverse event profile in 8245 patients with moderate hypercholesterolemia
-
Bradford RH, Shear CL, Chremos AN, et al. Expanded clinical evaluation of lovastatin (EXCEL) study results. 1. Efficacy in modifying plasma lipoproteins and adverse event profile in modifying plasma lipoproteins and adverse event profile in 8245 patients with moderate hypercholesterolemia. Arch Intern Med. 1991;151:43-49.
-
(1991)
Arch Intern Med
, vol.151
, pp. 43-49
-
-
Bradford, R.H.1
Shear, C.L.2
Chremos, A.N.3
-
48
-
-
0028096810
-
A review of clinical trials comparing HMG-CoA reductase inhibitors
-
Illingworth DR, Tobert JA. A review of clinical trials comparing HMG-CoA reductase inhibitors. Clin Ther. 1994;16:366-385.
-
(1994)
Clin Ther
, vol.16
, pp. 366-385
-
-
Illingworth, D.R.1
Tobert, J.A.2
-
50
-
-
0029166810
-
Interactions with hydroxymethylglutaryl-coenzyme A reductase inhibitor
-
Garnett WR. Interactions with hydroxymethylglutaryl-coenzyme A reductase inhibitor. Am J Health Syst Pharm. 1995;52:1639-1645.
-
(1995)
Am J Health Syst Pharm
, vol.52
, pp. 1639-1645
-
-
Garnett, W.R.1
-
51
-
-
0029996292
-
Warfarin-fluconazole. 1. Inhibition of human cytochrome P450-dependent metabolism of warfarin by fluconazole: In vitro studies
-
Kunze KL, Wienkers LC, Thummel KE, et al. Warfarin-fluconazole. 1. Inhibition of human cytochrome P450-dependent metabolism of warfarin by fluconazole: in vitro studies. Drug Metab Dispos. 1996;24:422-128.
-
(1996)
Drug Metab Dispos
, vol.24
, pp. 422-128
-
-
Kunze, K.L.1
Wienkers, L.C.2
Thummel, K.E.3
-
52
-
-
0029996292
-
Warfarin-fluconazole. II. A metabolically based drug interaction: In vitro studies
-
Black DJ, Kunze KL, Wienkers LC, et al. Warfarin-fluconazole. II. A metabolically based drug interaction: in vitro studies. Drug Metab Dispos. 1996;24:422-428.
-
(1996)
Drug Metab Dispos
, vol.24
, pp. 422-428
-
-
Black, D.J.1
Kunze, K.L.2
Wienkers, L.C.3
-
53
-
-
0027440142
-
Pharmacokinetic drug interactions with antimicrobial agents
-
Gillum JG, Isreal DS, Polk RE. Pharmacokinetic drug interactions with antimicrobial agents. Clin Pharmacokinet.1993;25:450-182.
-
(1993)
Clin Pharmacokinet
, vol.25
, pp. 450-182
-
-
Gillum, J.G.1
Isreal, D.S.2
Polk, R.E.3
-
54
-
-
0031919507
-
Delayed elevation of international normalized ratio with concurrent clarithromycin and warfarin therapy
-
Oberg KC. Delayed elevation of international normalized ratio with concurrent clarithromycin and warfarin therapy. Pharmacotherapy. 1998;18:386-391.
-
(1998)
Pharmacotherapy
, vol.18
, pp. 386-391
-
-
Oberg, K.C.1
-
55
-
-
0022398138
-
Omeprazole inhibits oxidative drug metabolism. Studies with diazepam and phenytoin in vivo and 7-ethoxycoumarin in vitro
-
Gugler R, Jensen JC. Omeprazole inhibits oxidative drug metabolism. Studies with diazepam and phenytoin in vivo and 7-ethoxycoumarin in vitro. Gastroenterolog.y 1985;89:1235-1241.
-
(1985)
Gastroenterolog.y
, vol.89
, pp. 1235-1241
-
-
Gugler, R.1
Jensen, J.C.2
-
56
-
-
0029976064
-
Newer antidepressants and the cytochrome P450 system
-
Nemeroff CB, DeVane L, Pollock BG. Newer antidepressants and the cytochrome P450 system. Am J Psychiatry. 1996;153:311-320.
-
(1996)
Am J Psychiatry
, vol.153
, pp. 311-320
-
-
Nemeroff, C.B.1
DeVane, L.2
Pollock, B.G.3
-
57
-
-
0029928537
-
Are pharmacokinetic drug interactions with SSRIs an issue?
-
Brosen K. Are pharmacokinetic drug interactions with SSRIs an issue? Int Clin Psychopharmaco.l 1996;ll(Suppl 1):23-27.
-
(1996)
Int Clin Psychopharmaco.l
, vol.100
, Issue.SUPPL. 1
, pp. 23-27
-
-
Brosen, K.1
-
58
-
-
0025222965
-
Torsades de pointes occurring in association with terfenidine use
-
Monahan BP, Ferguson CL, Killeavy ES, et al. Torsades de pointes occurring in association with terfenidine use. JAMA. 1990;264:2788-2790.
-
(1990)
JAMA
, vol.264
, pp. 2788-2790
-
-
Monahan, B.P.1
Ferguson, C.L.2
Killeavy, E.S.3
-
59
-
-
0036785060
-
Fluvoxamine augmentation of olanzapine in chronic schizophrenia: Pharmacokinetic interactions and clinical effects
-
Hiemke C, Avi P, Jabarin M, et al. Fluvoxamine augmentation of olanzapine in chronic schizophrenia: pharmacokinetic interactions and clinical effects. J Clin Psychopharmacol. 2002;22:502-506.
-
(2002)
J Clin Psychopharmacol
, vol.22
, pp. 502-506
-
-
Hiemke, C.1
Avi, P.2
Jabarin, M.3
-
60
-
-
0027468346
-
Terfenadine-ketoconazole interaction pharmacokinetic and electrocardiographic consequences
-
Honig PK, Woosley RL, Zamani K, et al. Terfenadine-ketoconazole interaction pharmacokinetic and electrocardiographic consequences. JAMA. 1993;269:1513-1518.
-
(1993)
JAMA
, vol.269
, pp. 1513-1518
-
-
Honig, P.K.1
Woosley, R.L.2
Zamani, K.3
-
61
-
-
0028298286
-
Inhibition of terfenidine metabolism: Pharmacokinetic and pharmacodynamic consequences
-
Kivisto KT, Neuvonen PJ, Klotz U. Inhibition of terfenidine metabolism: pharmacokinetic and pharmacodynamic consequences. Clin Pharmacokinet. 1994;7:1-5.
-
(1994)
Clin Pharmacokinet
, vol.7
, pp. 1-5
-
-
Kivisto, K.T.1
Neuvonen, P.J.2
Klotz, U.3
-
62
-
-
0027440142
-
Pharmacokinetic drug interactions with antimicrobial agents
-
Gillum JG, Isreal DS, Polk RE. Pharmacokinetic drug interactions with antimicrobial agents. Clin Pharmacokinet. 1993;25:450-482.
-
(1993)
Clin Pharmacokinet
, vol.25
, pp. 450-482
-
-
Gillum, J.G.1
Isreal, D.S.2
Polk, R.E.3
-
63
-
-
0028829791
-
QT interval prolongation and Torsades de pointes due to erythromycin lactobionate
-
Oberg K, Bauman JL. QT interval prolongation and Torsades de pointes due to erythromycin lactobionate. Pharmacotherapy. 1995;15:687-692.
-
(1995)
Pharmacotherapy
, vol.15
, pp. 687-692
-
-
Oberg, K.1
Bauman, J.L.2
-
64
-
-
0026671408
-
Changes in the pharmacokinetics and electrocardiographic pharmacodynamics of terfenidine with concomitant administration of erythromycin
-
Honig PK, Woosley RL, Zamani K, et al. Changes in the pharmacokinetics and electrocardiographic pharmacodynamics of terfenidine with concomitant administration of erythromycin. Clin Pharmacol Ther. 1992;52:213-218.
-
(1992)
Clin Pharmacol Ther
, vol.52
, pp. 213-218
-
-
Honig, P.K.1
Woosley, R.L.2
Zamani, K.3
-
65
-
-
0029092429
-
Macrolides versus azalides: A drug interaction update
-
Amsden GW. Macrolides versus azalides: a drug interaction update. Ann Pharmacother. 1995;29:906-917.
-
(1995)
Ann Pharmacother
, vol.29
, pp. 906-917
-
-
Amsden, G.W.1
-
66
-
-
0026758450
-
Tachycardia during cisapride treatment
-
Inman W, Kubota K. Tachycardia during cisapride treatment. BMJ. 1992;305:748-749.
-
(1992)
BMJ
, vol.305
, pp. 748-749
-
-
Inman, W.1
Kubota, K.2
-
67
-
-
84878057145
-
-
Arizona Center for Education and Research on Therapeutics, Available at:, Accessed March 25, 2007
-
Arizona Center for Education and Research on Therapeutics. Drugs with risk of Torsades de Pointes. Available at: http:/ /www.arizonacert.org/medical- pros/drug-lists/drug-lists.htm. Accessed March 25, 2007.
-
Drugs with risk of Torsades de Pointes
-
-
-
68
-
-
19244365446
-
Oral erythromycin and the risk of sudden death from cardiac causes
-
Ray WA, Murray KT, Meredith S, et al. Oral erythromycin and the risk of sudden death from cardiac causes. N Engl JMed. 2004;351:1089-1096.
-
(2004)
N Engl JMed
, vol.351
, pp. 1089-1096
-
-
Ray, W.A.1
Murray, K.T.2
Meredith, S.3
-
69
-
-
0034022551
-
Prolonged QT interval and torsades de pointes caused by the combination of fluconazole and amitriptyline
-
Dorsey ST, Biblo LA. Prolonged QT interval and torsades de pointes caused by the combination of fluconazole and amitriptyline. Am J Emerg Med. 2000;18:227-229.
-
(2000)
Am J Emerg Med
, vol.18
, pp. 227-229
-
-
Dorsey, S.T.1
Biblo, L.A.2
-
70
-
-
0001353072
-
Cardiac arrest associated with combination cisapride and itraconazole therapy
-
Hoover CA, Carmichael JK, Nolan PE Jr, et al. Cardiac arrest associated with combination cisapride and itraconazole therapy. J Cardiovasc Pharmacol Ther. 1996;1:255-258.
-
(1996)
J Cardiovasc Pharmacol Ther
, vol.1
, pp. 255-258
-
-
Hoover, C.A.1
Carmichael, J.K.2
Nolan Jr, P.E.3
-
71
-
-
0036896408
-
Probable case of torsades de pointes induced by fluconazole
-
Khazan M, Mathis AS. Probable case of torsades de pointes induced by fluconazole. Pharmacotherapy. 2002;22: 1632-1637.
-
(2002)
Pharmacotherapy
, vol.22
, pp. 1632-1637
-
-
Khazan, M.1
Mathis, A.S.2
-
72
-
-
0027267566
-
Itraconazole prevents terfenadine metabolism and increases risk of torsades de pointes ventricular tachycardia
-
Pohjola-Sintonen S, Viitasalo M, Toivonen L, et al. Itraconazole prevents terfenadine metabolism and increases risk of torsades de pointes ventricular tachycardia. Eur J Clin Pharmacol. 1993;45:191-193.
-
(1993)
Eur J Clin Pharmacol
, vol.45
, pp. 191-193
-
-
Pohjola-Sintonen, S.1
Viitasalo, M.2
Toivonen, L.3
-
73
-
-
0026752150
-
Torsades de pointes after treatment with terfenadine and ketocona-zole
-
Zimmermann M, Duruz H, Guinand O, et al. Torsades de pointes after treatment with terfenadine and ketocona-zole. Eur Heart J. 1992;13:1002-1003.
-
(1992)
Eur Heart J
, vol.13
, pp. 1002-1003
-
-
Zimmermann, M.1
Duruz, H.2
Guinand, O.3
-
75
-
-
0028951981
-
Long QT syndrome during high dose cisapride
-
Bran S, Murray W, Hirsch IB, et al. Long QT syndrome during high dose cisapride. Arch Intern Med. 1995;155:765-768.
-
(1995)
Arch Intern Med
, vol.155
, pp. 765-768
-
-
Bran, S.1
Murray, W.2
Hirsch, I.B.3
-
76
-
-
0029890375
-
Cisapride and fatal arrhythmia
-
Wysowski DK, Bacsanyi J. Cisapride and fatal arrhythmia. N Engl J Med. 1996;335:290-291.
-
(1996)
N Engl J Med
, vol.335
, pp. 290-291
-
-
Wysowski, D.K.1
Bacsanyi, J.2
-
77
-
-
0028280463
-
Possible interactions with terfenidine or astemizole
-
Zechnich AD, Hedges JR, Eiselt-Proteau D, et al. Possible interactions with terfenidine or astemizole. West J Med. 1994;160:321-325.
-
(1994)
West J Med
, vol.160
, pp. 321-325
-
-
Zechnich, A.D.1
Hedges, J.R.2
Eiselt-Proteau, D.3
-
79
-
-
0029947311
-
Drug interactions, cardiac toxicity, and terfenadine: From bench to clinic?
-
Flockhart DA. Drug interactions, cardiac toxicity, and terfenadine: from bench to clinic? J Clin Psychopharmacol. 1996;16:101-103.
-
(1996)
J Clin Psychopharmacol
, vol.16
, pp. 101-103
-
-
Flockhart, D.A.1
-
80
-
-
0028218139
-
Grapefruit juice inhibits 7-hydroxylation of coumarin in healthy volunteers
-
Merkel U, Sigusch H, Hoffman A. Grapefruit juice inhibits 7-hydroxylation of coumarin in healthy volunteers. Eur J Clin Pharmacol. 1994;46:175-177.
-
(1994)
Eur J Clin Pharmacol
, vol.46
, pp. 175-177
-
-
Merkel, U.1
Sigusch, H.2
Hoffman, A.3
-
81
-
-
28044463813
-
QT prolongation and torsades de pointes among methadone users: Reports to the FDA spontaneous reporting system
-
Pearson EC, Woosley RL. QT prolongation and torsades de pointes among methadone users: reports to the FDA spontaneous reporting system. Pharmacoepidemiol Drug Saf. 2005;14:747-753.
-
(2005)
Pharmacoepidemiol Drug Saf
, vol.14
, pp. 747-753
-
-
Pearson, E.C.1
Woosley, R.L.2
-
82
-
-
0037125849
-
Torsade de pointes associated with very high dose methadone
-
Krantz MJ, Lewkowiez L, Hays H, et al. Torsade de pointes associated with very high dose methadone. Ann Intern Med. 2002;137:501-504.
-
(2002)
Ann Intern Med
, vol.137
, pp. 501-504
-
-
Krantz, M.J.1
Lewkowiez, L.2
Hays, H.3
-
83
-
-
33746885502
-
Methadone associated Torsades de Pointes (polymorphic ventricular tachycardia) in opioid-dependent patients
-
Justo D, Gal-Oz A, Paran Y, et al. Methadone associated Torsades de Pointes (polymorphic ventricular tachycardia) in opioid-dependent patients. Addiction. 2006;101:1333-1338.
-
(2006)
Addiction
, vol.101
, pp. 1333-1338
-
-
Justo, D.1
Gal-Oz, A.2
Paran, Y.3
-
84
-
-
64549162267
-
Cardiovascular drug interactions
-
Frishman WH, Sonnenblick EH, Sica DA, eds, ed 2. New York: McGraw Hill
-
Opie LH. Cardiovascular drug interactions. In: Frishman WH, Sonnenblick EH, Sica DA, eds. Cardiovascular Pharmacotherapeutics, ed 2. New York: McGraw Hill, 2003: 875-891.
-
(2003)
Cardiovascular Pharmacotherapeutics
, pp. 875-891
-
-
Opie, L.H.1
|