Reactive oxygen species generated by thiopurine/UVA cause irreparable transcription-blocking DNA lesions

Nucleic Acids Research

Volumn 37, Issue 6, 2009, Pages 1951-1961

  Brem, Reto ^a   Li, Feng ^a   Karran, Peter ^a  

^a IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GUANINE 6 SULFONIC ACID; MERCAPTOPURINE; REACTIVE OXYGEN METABOLITE; RNA POLYMERASE II; SULFONIC ACID DERIVATIVE; TIOGUANINE; UNCLASSIFIED DRUG; ANTINEOPLASTIC ANTIMETABOLITE; DNA;

ARTICLE; COCKAYNE SYNDROME; CONTROLLED STUDY; DNA DAMAGE; DNA STRAND; EXCISION REPAIR; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IN VITRO STUDY; IN VIVO STUDY; PHOTOSENSITIVITY; PRIORITY JOURNAL; PROTEIN DNA INTERACTION; RADIATION INJURY; TRANSCRIPTION REGULATION; UBIQUITINATION; ULTRAVIOLET A RADIATION; CELL LINE; CHEMISTRY; DNA REPAIR; DRUG EFFECT; GENETIC TRANSCRIPTION; METABOLISM; RADIATION EXPOSURE; ULTRAVIOLET RADIATION;

ANTIMETABOLITES, ANTINEOPLASTIC; CELL LINE; DNA; DNA DAMAGE; DNA REPAIR; HUMANS; REACTIVE OXYGEN SPECIES; RNA POLYMERASE II; THIOGUANINE; TRANSCRIPTION, GENETIC; ULTRAVIOLET RAYS;

EID: 64549098978     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkp070     Document Type: Article

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