Reflux changes in adenoidal hyperplasia: A controlled prospective study to investigate its aetiology

Clinical Otolaryngology

Volumn 34, Issue 2, 2009, Pages 120-126

  Harris, P K ^a   Hussey, D J ^a,b   Watson, D I ^b   Mayne, G C ^b   Bradshaw, A ^a   Joniau, S ^a   Tan, L W ^c   Wormald, P J ^b,c   Carney, A S ^a,b  

^a FLINDERS MEDICAL CENTRE   (Australia)

^b FLINDERS UNIVERSITY   (Australia)

^c UNIVERSITY OF ADELAIDE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CARBONATE DEHYDRATASE III; CYCLOOXYGENASE 2; MUCIN 5AC; PEPSIN A;

ADENOID; ADENOID HYPERPLASIA; ADENOIDECTOMY; ARTICLE; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; DENTAL SURGERY; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LARYNGOPHARYNGEAL REFLUX; LYMPHOID HYPERPLASIA; MALE; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ADENOIDECTOMY; ADENOIDS; BIOPSY; CARBONIC ANHYDRASE III; CHILD; CHILD, PRESCHOOL; CYCLOOXYGENASE 2; FEMALE; GASTROESOPHAGEAL REFLUX; GENE EXPRESSION; HUMANS; HYPERPLASIA; MALE; MUCIN 5AC; PEPSIN A; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RISK FACTORS; STATISTICS AS TOPIC;

EID: 64549087685     PISSN: 17494478     EISSN: 17494486     Source Type: Journal    
DOI: 10.1111/j.1749-4486.2008.01852.x     Document Type: Article

References (28)

1. Shatz A. (2004) Indications and outcomes of adenoidectomy in infancy. Ann. Otol. Rhinol. Laryngol. 113, 835 838
2. Robb P.J. (2007) Adenoidectomy: does it work? J. Laryngol. Otol. 121, 209 214
3. Keles B., Ozturk K., Arbag H. et al. (2005) Frequency of pharyngeal reflux in children with adenoid hyperplasia. Int. J. Pediatr. Otorhinolaryngol. 69, 1103 1107
4. Abd El-Fattah A.M., Abdul Maksoud G.A., Ramadan A.S. et al. (2007) Pepsin assay: a marker for reflux in pediatric glue ear. Otolaryngol. Head Neck Surg. 136, 464 470
5. Tasker A., Dettmar P.W., Panetti M. et al. (2002) Is gastric reflux a cause of otitis media with effusion in children? Laryngoscope 112, 1930 1934
6. Lieu J.E., Muthappan P.G. Uppaluri R. (2005) Association of reflux with otitis media in children. Otolaryngol. Head Neck Surg. 133, 357 361
7. He Z., O'Reilly R.C., Bolling L. et al. (2007) Detection of gastric pepsin in middle ear fluid of children with otitis media. Otolaryngol. Head Neck Surg. 137, 59 64
8. Kadhim A.L., Spilsbury K., Semmens J.B. et al. (2007) Adenoidectomy for middle ear effusion: a study of 50,000 children over 24 years. Laryngoscope 117, 427 433
9. Joniau S., Bradshaw A., Esterman A. et al. (2007) Reflux and laryngitis: a systematic review. Otolaryngol. Head Neck Surg. 136, 686 692
10. Mandell D.L. Yellon R.F. (2007) Synchronous airway lesions and esophagitis in young patients undergoing adenoidectomy. Arch. Otolaryngol. Head Neck Surg. 133, 375 378
11. Johnston N., Bulmer D., Gill G.A. et al. (2003) Cell biology of laryngeal epithelial defenses in health and disease: further studies. Ann. Otol. Rhinol. Laryngol. 112, 481 491
12. Johnston N., Dettmar P.W., Lively M.O. et al. (2006) Effect of pepsin on laryngeal stress protein (Sep70, Sep53, and Hsp70) response: role in laryngopharyngeal reflux disease. Ann. Otol. Rhinol. Laryngol. 115, 47 58
13. Johnston N., Knight J., Dettmar P.W. et al. (2004) Pepsin and carbonic anhydrase isoenzyme III as diagnostic markers for laryngopharyngeal reflux disease. Laryngoscope 114, 2129 2134
14. Gill G.A., Johnston N., Buda A. et al. (2005) Laryngeal epithelial defenses against laryngopharyngeal reflux: investigations of E-cadherin, carbonic anhydrase isoenzyme III, and pepsin. Ann. Otol. Rhinol. Laryngol. 114, 913 921
15. Johnston N., Dettmar P.W., Bishwokarma B. et al. (2007) Activity/stability of human pepsin: implications for reflux attributed laryngeal disease. Laryngoscope 117, 1036 1039
16. Knight J., Lively M.O., Johnston N. et al. (2005) Sensitive pepsin immunoassay for detection of laryngopharyngeal reflux. Laryngoscope 115, 1473 1478
17. Ylitalo R. Thibeault S.L. (2006) Relationship between time of exposure of laryngopharyngeal reflux and gene expression in laryngeal fibroblasts. Ann. Otol. Rhinol. Laryngol. 115, 775 783
18. Sung M.W., Roh J.L., Park B.J. et al. (2003) Bile acid induces cyclo-oxygenase-2 expression in cultured human pharyngeal cells: a possible mechanism of carcinogenesis in the upper aerodigestive tract by laryngopharyngeal reflux. Laryngoscope 113, 1059 1063
19. Muller P.Y., Janovjak H., Miserez A.R. et al. (2002) Processing of gene expression data generated by quantitative real-time RT-PCR. Biotechniques 32, 1372 1374 1376, 1378-1379
20. Lurje G., Vallbohmer D., Collet P.H. et al. (2007) COX-2 mRNA expression is significantly increased in acid-exposed compared to nonexposed squamous epithelium in gastroesophageal reflux disease. J. Gastrointest. Surg. 11, 1105 1111
21. Peng J.P., Su C.Y., Chang H.C. et al. (2002) Overexpression of cyclo-oxygenase 2 in squamous cell carcinoma of the hypopharynx. Hum. Pathol. 33, 100 104
22. Ali M.S., Wilson J.A., Bennett M. et al. (2007) Mucin gene expression in hypertrophic adenoids. Acta Otolaryngol. 127, 1080 1085
23. Kerschner J.E. (2007) Mucin gene expression in human middle ear epithelium. Laryngoscope 117, 1666 1676
24. Lin J., Tsuprun V., Kawano H. et al. (2001) Characterization of mucins in human middle ear and Eustachian tube. Am. J. Physiol. Lung Cell Mol. Physiol. 280, L1157 L1167
25. Elsheikh M.N. Mahfouz M.E. (2006) Up-regulation of MUC5AC and MUC5B mucin genes in nasopharyngeal respiratory mucosa and selective up-regulation of MUC5B in middle ear in pediatric otitis media with effusion. Laryngoscope 116, 365 369
26. Lopez-Ferrer A., Curull V., Barranco C. et al. (2001) Mucins as differentiation markers in bronchial epithelium. Squamous cell carcinoma and adenocarcinoma display similar expression patterns. Am. J. Respir. Cell Mol. Biol. 24, 22 29
27. Gryczynska D., Kobos J. Zakrzewska A. (1999) Relationship between passive smoking, recurrent respiratory tract infections and otitis media in children. Int. J. Pediatr. Otorhinolaryngol. 49 (Suppl. 1 S275 S278
28. Modrzynski M. Zawisza E. (2007) An analysis of the incidence of adenoid hypertrophy in allergic children. Int. J. Pediatr. Otorhinolaryngol. 71, 713 719