Radiofrequency ablation of airway smooth muscle for sustained treatment of asthma: Preliminary investigations

European Respiratory Journal

Volumn 24, Issue 4, 2004, Pages 659-663

  Cox, P G ^a   Miller, J ^b   Mitzner, W ^c   Leff, A R ^d,e  

^a MCMASTER UNIVERSITY   (Canada)

^b MCMASTER UNIVERSITY   (Canada)

^c DEPARTMENT OF PATHOLOGY   (United States)

^d UNIVERSITY OF CHICAGO   (United States)

^e UNIVERSITY OF CHICAGO MEDICAL CENTER   (United States)

Author keywords

Asthma airway smooth muscle; Asthma treatment

Indexed keywords

BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; BRONCHODILATING AGENT; CORTICOSTEROID; METHACHOLINE;

AIRWAY; ARTICLE; ASTHMA; BRONCHOSCOPY; BRONCHOSPASM; BRONCHUS HYPERREACTIVITY; DOG; EUROPE; FEASIBILITY STUDY; HEALTH CARE ORGANIZATION; HEAT TREATMENT; HUMAN; LUNG FIBROSIS; NONHUMAN; NORTH AMERICA; PATIENT ATTITUDE; PATIENT COMPLIANCE; PRIORITY JOURNAL; RADIOFREQUENCY; RESEARCH ETHICS; RESPIRATORY TRACT INJURY; SAFETY; SMOOTH MUSCLE; SYMPTOM; TREATMENT OUTCOME;

ANIMALS; ASTHMA; BRONCHI; CATHETER ABLATION; CLINICAL TRIALS; HUMANS; MUSCLE, SMOOTH;

EID: 6444236644     PISSN: 09031936     EISSN: None     Source Type: Journal    
DOI: 10.1183/09031936.04.00054604     Document Type: Article

References (25)

1. Murray PT, Corbridge T. Pharmacotherpy of Asthma. In: Hall JB, Corbridge TC, Rodrigo C, Rodrigo G, eds. Acute Asthma: Assessment and Management. New York, McGraw-Hill Companies Inc., 2000; pp. 139-160.
2. National Institutes of Health, National Heart and Lung Institute. Practical Guide for the Diagnosis and Management of Asthma. US Department of Health and Human Services, NIH Publication No. 97-4053, October, 1997.
3. O'Byrne P, Barnes PJ, Rodriguez-Roisin R, et al. Low dose inhaled budesonide and formoterol in mild persistent asthma. Am J Respir Crit Care Med 2001; 164: 1392-1397.
4. 2-adrenergic receptor on the response to regular use of albuterol in asthma. Am J Respir Crit Care Med 2000; 162: 75-80.
5. Carroll N, Elliot J, Morton A, James A. The structure of large and small airways in nonfatal and fatal asthma. Am Rev of Respir Dis 1993; 147: 405-410.
6. Nadel JA, Busse WW. Asthma. Am J Respir Crit Care Med 1998; 157: S130-S138.
7. Drazen JM. Asthma therapy with agents preventing leukotriene synthesis or action. Proc Assoc Am Physicians 1999; 111: 547-559.
8. Leckie MN, ten Brinke A, Knan J, et al. Effect of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyperesponiveness and the late asthmatic response. Lancet 2000; 356: 2144-2148.
9. Busse W, Corren J, Lanier BQ et al. Omalizumab, anti-IgE recombinant humanized monoclonal antibody, and the treatment of severe allergic asthma. J Allergy Clin Immunol 2001; 108: 184-190.
10. Weibel ER. Morphometry of the Human Lung. New York: Academic Press, 1963.
11. Horsfield K, Cumming G. Morphology of the bronchial tree in man. J Appl Physiol 1968; 24: 373-383.
12. Horsfield K, Cumming G. Morphology of the bronchial tree in the dog. Respir Physiol 1976; 26: 173-182.
13. Pedley TJ, Schroter RC, Sudlow MF. Gas flow and mixing in the airways. In: West JB, ed. Bioengineering Aspects of the Lung. New York: Marcel Dekker Inc., 1977, pp. 163-265.
14. Brown RH, Mitzner W. The myth of maximal airway responsiveness in vivo. J Appl Physiol 1998; 85: 2012-2017.
15. Pellegrino R, Biggi A, Papaleo A, Gianfranco C, Rodarte JR, Brusasco V. Regional expiratory flow limitation studied with Technegas in asthma. J Appl Physiol 2001; 91: 2190-2198.
16. Mitzner W. Airway smooth muscle: the appendix of the lung. Am J Respir Crit Care Med 2004; 169: 1-4.
17. Seow CY, Fredberg JJ. Historical perspective on airway smooth muscle: the saga of a frustrated cell. J Appl Physiol 2001; 91: 938-952.
18. Macklin CC. The musculature of the bronchi and lungs. Physiol Reviews 1929; 9: 1-60.
19. Danek CJ, Lombard CM, Dungworth DL, et al. Reduction in airway hyperresponsiveness to methacholine by the application of RF energy in dogs. J Appl Physiol 2004; (In press).
20. Miller P, Danek CJ, Cox G, Miller J. Development of a bronchoscopic technique for airway diameter measurement. Chest 2001; 120: 229s.
21. Cox G, Miller J, McWilliams A, Fitzgerald M, Lam S. Bronchial thermoplasty: one-year update. Am J Respir Crit Care Med 2004; 169: A313.
22. Miller JD, Cox G, Vincic L, Lombard CM, Loomas BE, Danek CJ. Bronchial thermoplasty is well tolerated by non-asthmatic patients requiring lobectomy. Am J Respir Crit Care Med 2002; 165: A216.
23. Lombard CM, Vincic L, Cox G, et al. Histological effects of bronchial thermoplasty of canine and human airways. Am J Respir Crit Care Med 2002; 165: A779.
24. Cox G, Miller JD, Noth I, et al. Early clinical experience with bronchial thermoplasty for the treatment of asthma. Am J Respir Crit Care Med 2002; 165: A187.
25. Laviolette M, Thomson N, Niven R, et al. Asthma intervention research (AIR) trial: early safety assessment of bronchial thermoplasty. Am J Respir Crit Care Med 2004; 169: A314.